Abstract: An integrated, self-contained microrefrigeration apparatus, in a dimension small enough to fit inside small appliances, such as electronic cases and portable equipment is described. The microrefrigerator employs a working fluid that circulates between evaporator, compressor, condenser and turbine-expander components in a closed loop. Two configurations are claimed: one with the compressor and turbine operating on independent shafts, and the other with the turbine and compressor both operating on the motor shaft.

Abstract: A method and apparatus for actively cooling a device, space or circuit board are disclosed. The device may be an electrical or electronic component that includes an integrated circuit or embedded control. The apparatus employs a fluid in a closed loop, at least two heat exchangers and a fluid driver.

Abstract: The present invention provides a means for the recovery of any residual specialty oil from a cake using a compressed solvent, preferably carbon dioxide. The present invention also allows for the cake to be pretreated before extraction. The compressed solvent can be recycled and the process is continuous.

Abstract: The present invention provides a method and apparatus for fraction collection from a chromatographic system. One or more substances of interest from a sample are collected in high concentration with high efficiency.

Abstract: The present invention provides a means for the recovery of residual specialty oils from cake using a compressed solvent, preferably carbon dioxide. The present invention also allows for the cake to be toasted before extraction. The compressed solvent can be recycled and the process is continuous.

Abstract: The present invention provides methods for and compositions of anticancer medicaments. These compositions are comprised of nanoparticles or microparticles produced by antisolvent technology. The particles can be used to treat cancerous tissues in humans or animals.

Abstract: A thin-plate microchannel structure of channel depth of 500 microns or less and capable of withstanding pressure up to 6,000 psi inch is disclosed. The thin-plate microchannel structure may be formed from metal, ceramic or polymeric materials. It can be employed to facilitate the exchange of heat between a single fluid in liquid, gaseous or supercritical state and another device, such as an integrated circuit, with which it is near or in contact.

Abstract: A cooling cycle is disclosed employing carbon dioxide in a supercritical state throughout the cycle. Heat absorption depends solely on the heat capacity of the fluid as it flows through the hot zone. Consequently, there is no change of state, as would be the case in evaporative heat absorption. The supercritical carbon dioxide is maintained above the dew point that could be expected for devices operating indoors or outdoors.

Abstract: Methods and apparatuses for cooling a device are disclosed. The device may be an electrical or electronic component that includes an integrated circuit or embedded control. The apparatus employs a fluid that near or above its critical pressure and at least one heat exchanger. At least two configurations are disclosed: one with a pump and another without a pump.

Abstract: The present invention provides a method and apparatus for producing polymorphs of a desired substance providing a plurality of enclosed spaces. The temperature and pressure of the enclosed spaces can be controlled. Various crystal identification means can be used to identify the polymorphic form of the solidified substance.

Abstract: The present invention provides a means for constructing a brushless canned motor that is compact enough to be suitable for use in small appliances, such as electronic devices. The rotating parts of the motor are encapsulated within a can such that the motor can be hermetically connected to a driven device.

Abstract: The present invention provides methods and apparatuses for the continuous processing and solids handling in near-critical and supercritical fluids. The present invention also allows for treatment of the starting material with the near-critical or supercritical fluid. The remaining raffinate is then continuously transferred and may be collected in a barrier fluid.

Abstract: The present invention provides a method and device for collecting and concentrating a desired compound from a chromatographic column exit stream. The collection chamber can be heated or cooled and washed in a forward or backward direction for efficient removal.

Abstract: The present invention provides a method and apparatus for the recovery of desired substances from a feed material having a given solubility in carbon dioxide. The present invention also provides a means for increasing energy efficiency in the recovery of desired substances by adding a compressor into the recovery process, as well as using tap water to cool the extraction fluid. The present invention also provides a means for energy reduction in high pressure recycling by replacing the expansion valve with a turbine. The present invention also provides a means of energetically coupling the turbine to the pump.

Abstract: The present invention provides a method and an apparatus for separating soluble substances from a starting material using a compressed fluid. The present invention also provides a means for reducing the solvent to feed ratio and breakup of the starting material stream into fine droplets by refluxing a portion of the outlet stream from the extraction vessel. The present invention also provides a means for transferring and collecting the insoluble substances that are left in the extraction vessel. The present invention also provides for a phospholipid composition produced from the process of using a compressed fluid for the removal of residual alcohol. The residual alcohol content in the phospholipid composition is less than 0.5%.

Abstract: The present invention provides a method and device for collecting and concentrating a desired compound from a chromatographic column exit stream. The collection chamber can be heated or cooled and washed in a forward or backward direction for efficient removal.

Abstract: The present invention provides a novel method of actuation for valve-less positive displacement reciprocating pumps. It also allows for variation of pumping volume by altering the speed of the motor, typically by adjusting the voltage. Use of the valve-less piston allows for compact design and it simplifies the construction, thereby ensuring reliable service.

Abstract: The present invention provides a means for the recovery of residual specialty oils from cake using a compressed solvent, preferably carbon dioxide. The present invention also allows for the cake to be toasted before extraction. The compressed solvent can be recycled and the process is continuous.

Abstract: The present invention provides a method and device for collecting and concentrating a desired compound from a chromatographic column exit stream. The collection chamber can be heated or cooled and washed in a forward or backward direction for efficient removal.

Abstract: Methods and apparatuses for cooling a device are disclosed. The device may be an electrical or electronic component that includes an integrated circuit or embedded control. The apparatus employs a fluid that near or above its critical pressure and at least one heat exchanger. At least two configurations are disclosed: one with a pump and another without a pump.