Abstract: The invention provides methods for improving efficiency of fermentation by arginine supplementation, and genetically modified bacterium for use therefor. More particularly the invention provides methods for (i) increasing the production ATP intensive products with arginine supplementation, (ii) increasing utilization of arginine by a C1-fixing bacterium; and (iii) providing C1-fixing bacterium with optimized arginine de-aminase pathways.

Abstract: The invention provides methods for improving efficiency of fermentation by arginine supplementation, and genetically modified bacterium for use therefor. More particularly the invention provides methods for (i) increasing the production ATP intensive products with arginine supplementation, (ii) increasing utilization of arginine by a C1-fixing bacterium; and (iii) providing C1-fixing bacterium with optimized arginine de-aminase pathways.

Abstract: The invention provides methods for improving efficiency of fermentation by arginine supplementation, and genetically modified bacterium for use therefor. More particularly the invention provides methods for (i) increasing the production ATP intensive products with arginine supplementation, (ii) increasing utilization of arginine by a C1-fixing bacterium; and (iii) providing C1-fixing bacterium with optimized arginine de-aminase pathways.

Abstract: Disclosed herein are new strains of Propionibacterium and methods for the biosynthetic production of propionic acid.

Abstract: Disclosed herein are new strains of Propionibacterium and methods for the biosynthetic production of propionic acid.

Abstract: The invention provides methods for improving efficiency of fermentation by arginine supplementation, and genetically modified bacterium for use therefor. More particularly the invention provides methods for (i) increasing the production ATP intensive products with arginine supplementation, (ii) increasing utilization of arginine by a C1-fixing bacterium; and (iii) providing C1-fixing bacterium with optimized arginine de-aminase pathways.

Abstract: A fiber optic assembly includes first and second fiber optic ribbons and a splice protector. Each of the first and second fiber optic ribbons includes a plurality of optical fibers coupled in a substantially flat arrangement, where the optical fibers are aligned side-by-side with one another. The optical fibers of the first ribbon are fusion spliced with the optical fibers of the second ribbon such that the spliced ribbons at the splice have a common lengthwise axis, widthwise axis orthogonal to the lengthwise axis, and thickness axis orthogonal to the lengthwise and widthwise axes. The splice protector supports the optical fibers of the first and second fiber optic ribbons that are spliced to one another at the splice. The splice protector includes an ultra-violet light (UV-) curable adhesive that provides a flexible support for the splice, and is at least half as flexible when cured over the splice as the first and second ribbons in bending about the widthwise axis.

Abstract: A fiber optic cable assembly includes a fiber optic cable, a tether, and an overmold. The fiber optic cable includes an optical fiber, a strength member, and a jacket, where the jacket includes an interior portion contacting the strength member and an exterior portion adjoining the interior portion. The interior and exterior portions of the jacket both include polyethylene, and the exterior portion further includes an additive that is not in the interior portion. The tether is coupled to the fiber optic cable at an attachment point. The optical fiber or another optical fiber spliced to the optical fiber, diverges from the fiber optic cable via the tether. The overmold encloses the attachment point and is attached directly to a discrete section of the exterior portion of the jacket proximate to the attachment point. The additive facilitates bonding of the overmold to the discrete section.

Abstract: A fiber optic assembly includes first and second fiber optic ribbons and a splice protector. Each of the first and second fiber optic ribbons includes a plurality of optical fibers coupled in a substantially flat arrangement, where the optical fibers are aligned side-by-side with one another. The optical fibers of the first ribbon are fusion spliced with the optical fibers of the second ribbon such that the spliced ribbons at the splice have a common lengthwise axis, widthwise axis orthogonal to the lengthwise axis, and thickness axis orthogonal to the lengthwise and widthwise axes. The splice protector supports the optical fibers of the first and second fiber optic ribbons that are spliced to one another at the splice. The splice protector includes an ultra-violet light (UV-) curable adhesive that provides a flexible support for the splice, and is at least half as flexible when cured over the splice as the first and second ribbons in bending about the widthwise axis.

Abstract: A method is provided for producing a population of post-mitotic cells of the neutrophil lineage, which method comprises the ex vivo steps of: (a) providing a population of cells comprising neutrophil progenitor cells; and (b) culturing the population of cells in an animal cell culture medium comprising (i) one or more early acting cytokines and (ii) one or more cytokines that differentiate said progenitor cells into a neutrophil specific lineage, under conditions of low oxidative stress, the culture medium being agitated when the cells are at a cell density at which oxygen transfer via the surface of the culture medium is insufficient for growth of the progenitor cells and the progeny thereof under static conditions, to produce a population of post-mitotic cells of the neutrophil lineage. The resulting population of cells can be used to increase the number of neutrophils in a patient.

Abstract: Flexible closures and other flexible optical assemblies that are installed within a factory, or in the field, and then deployed using cable installation methods, wherein the flexible closures and assemblies have the ability to bend and twist without incurring physical damage to their structure, optical fibers and splices disposed within, and without significant attenuation in the optical fibers when exposed to conventional installation stresses. Flexible closures that replace conventional substantially rigid closures in order to facilitate pre-engineered and assembled distribution cable installation within an optical network, and the physical, bending and material properties of such closures, and methods of manufacturing and installing the same.

Abstract: A pre-connectorized fiber optic distribution cable assembly includes a plurality of optical fibers and at least one mid-span access location along the length of the distribution cable. At least one of the optical fibers is accessed, terminated and then connectorized at the mid-span access location to an optical connector disposed within a receptacle. The mid-span access location, the accessed, terminated and connectorized optical fiber, the optical connector and at least a portion of the receptacle are encapsulated with a protective overmolded shell. A tether including at least one optical fiber connectorized at a first end of the tether is optically connected to the optical connector through the receptacle. A second end of the tether opposite the first end terminates in a network optical connection terminal, thereby compensating for a span length measurement difference between the actual location of the mid-span access and the desired location of the optical connection terminal.

Abstract: A fiber optic cable assembly comprising a first fiber optic cable having pre-selected optical fibers pre-terminated and branched at a cable access point, a second cable optically connected to the pre-terminated optical fibers, and a flexible body encapsulating the cable access point. A method for manufacturing a fiber optic cable assembly comprising providing a fiber optic cable, making an opening in the cable for access, pre-terminating pre-selected optical fibers, optically connecting the pre-selected optical fibers with optical fibers of a tether cable, and encapsulating at least a portion of the cable access location within a flexible overmolded body.

Abstract: A cable assembly comprising a first fiber optic cable, a second fiber optic cable attached to the first fiber optic cable, and an apparatus for remotely releasing at least a portion of the second fiber optic cable from attachment to the first fiber optic cable. A cable assembly comprising a distribution cable, a tether cable attached and optically interconnected to the distribution cable at a first position, and removably attached to the distribution cable at one or more second positions, and a tether cable release apparatus for remotely releasing at least a portion of the tether cable from the distribution cable to allow the tether and a tethered assembly to be pulled to a predetermined location within a network.

Abstract: A fiber optic cable assembly comprising a first fiber optic cable having pre-selected optical fibers pre-terminated and branched at a cable access point, a second cable optically connected to the pre-terminated optical fibers, and a flexible body encapsulating the cable access point. A method for manufacturing a fiber optic cable assembly comprising providing a fiber optic cable, making an opening in the cable for access, pre-terminating pre-selected optical fibers, optically connecting the pre-selected optical fibers with optical fibers of a tether cable, and encapsulating at least a portion of the cable access location within a flexible overmolded body.

Abstract: A fiber optic cable assembly comprising a first fiber optic cable having pre-selected optical fibers pre-terminated and branched at a cable access point, a second cable optically connected to the pre-terminated optical fibers, and a flexible body encapsulating the cable access point. A method for manufacturing a fiber optic cable assembly comprising providing a fiber optic cable, making an opening in the cable for access, pre-terminating pre-selected optical fibers, optically connecting the pre-selected optical fibers with optical fibers of a tether cable, and encapsulating at least a portion of the cable access location within a flexible overmolded body.

Abstract: A cable assembly comprising a first fiber optic cable, a second fiber optic cable attached to the first fiber optic cable, and an apparatus for remotely releasing at least a portion of the second fiber optic cable from attachment to the first fiber optic cable. A cable assembly comprising a distribution cable, a tether cable attached and optically interconnected to the distribution cable at a first position, and removably attached to the distribution cable at one or more second positions, and a tether cable release apparatus for remotely releasing at least a portion of the tether cable from the distribution cable to allow the tether and a tethered assembly to be pulled to a predetermined location within a network.

Abstract: Flexible closures and other flexible optical assemblies that are installed within a factory, or in the field, and then deployed using cable installation methods, wherein the flexible closures and assemblies have the ability to bend and twist without incurring physical damage to their structure, optical fibers and splices disposed within, and without significant attenuation in the optical fibers when exposed to conventional installation stresses. Flexible closures that replace conventional substantially rigid closures in order to facilitate pre-engineered and assembled distribution cable installation within an optical network, and the physical, bending and material properties of such closures, and methods of manufacturing and installing the same.

Abstract: An overmolded multi-port optical connection terminal for a fiber optic distribution cable includes a tether cable containing a plurality of optical fibers optically connected to a corresponding plurality of optical fibers terminated from the fiber optic distribution cable at a first end of the tether cable, an overmolded housing a the second end of the tether cable, at least one connector port, and plenum means for accommodating excess fiber length (EFL) caused by shrinkage of the tether cable and/or pistoning of the optical fibers of the tether cable during connector mating. In one embodiment, a centralized plenum means is defined by an internal cavity within the overmolded housing sufficient for accommodating the EFL without micro bending. In another embodiment, a distributed plenum means is defined by an oversized tubular portion of the tether cable having an inner diameter sufficient for accommodating the EFL without micro bending.

Abstract: A pre-connectorized fiber optic distribution cable assembly includes a plurality of optical fibers and at least one mid-span access location along the length of the distribution cable. At least one of the optical fibers is accessed, terminated and then connectorized at the mid-span access location to an optical connector disposed within a receptacle. The mid-span access location, the accessed, terminated and connectorized optical fiber, the optical connector and at least a portion of the receptacle are encapsulated with a protective overmolded shell. A tether including at least one optical fiber connectorized at a first end of the tether is optically connected to the optical connector through the receptacle. A second end of the tether opposite the first end terminates in a network optical connection terminal, thereby compensating for a span length measurement difference between the actual location of the mid-span access and the desired location of the optical connection terminal.