Abstract: The present disclosure discloses a fibroblast growth factor receptor (FGFR)-targeting antagonistic short peptide, namely a short peptide compound P48 with the amino acid sequence of Ser-Pro-Pro-Arg-Tyr-Pro-Gly-Gly-Gly-Ser-NH2, where the short peptide compound P48 inhibits an FGFR pathway to inhibit cell proliferation and migration.

Abstract: The present disclosure relates to a two-plasmid system for prime editing in yeast, use thereof, and a method for gene prime editing in yeast. The two-plasmid system includes a first plasmid and a second plasmid. The first plasmid includes a sequence encoding for an epegRNA. The epegRNA is an RNA molecule including a motif at a 3?-terminus of a pegRNA, and the motif having a sequence as set forth in SEQ ID NO. 12. The second plasmid includes a sequence encoding for a fusion protein of a nucleic acid nickase nCas9 fused with a reverse transcriptase M-MLV RT. The two-plasmid expression system can be used in gene editing in yeast.

Abstract: A system adapted to detect rotation of at least two spray arms of a household appliance spaced along a longitudinal axis of the appliance includes a first detection magnet, a second detection magnet and a magnetic sensor. The first detection magnet is arranged on a first spray arm of the at least two spray arms. The second detection magnet is arranged on a second spray arm of the at least two spray arms. A magnetic field direction of the second detection magnet is different from a magnetic field direction of the first detection magnet. The magnetic sensor is arranged in the household appliance and is adapted to sense a motion status of the first detection magnet and the second detection magnet.

Abstract: Disclosed is a fluorescent PCR method for detecting HLA-B*15:02 allele and a specific primer probe combination. In the present disclosure, a set of primers and probes are designed based on an HLA-B*15:02 specific SNP gene locus by using TaqMan probe technology, combining another set of primers and probes corresponding to the internal reference gene ?-Actin, and a set of primer probe for non-HLA-B*15:02 genes are designed to detect whether a DNA sample contains an HLA-B*15:02 gene and whether a sample is homozygous or heterozygous. Compared with the similar detection methods in the past, the technical scheme in the present disclosure inherits the advantages of high specificity, high throughput, high resolution, low cost, simple and convenient operation, process controllability and the like of the fluorescent PCR, and may detect whether a sample is homozygous or heterozygous.

Abstract: A metasurface unit includes a first metal layer, a first dielectric layer, a second metal layer, a second dielectric layer, and a third metal layer. The first metal layer includes a first dipole arm pair and a second dipole arm pair, the first dipole arm pair is disposed in a first direction, and the second dipole arm pair is disposed in a second direction perpendicular to the first direction. The second metal layer includes at least one of the following: metal unit structures arranged at an equal distance in a third direction, metal unit structures arranged at an equal distance in a fourth direction perpendicular to the third direction, and metal unit structures arranged at an equal distance in the third direction and the fourth direction. The third direction and the first direction or the second direction are parallel or have a first included angle.

Abstract: A mattress centrifugal dehydration device which includes a frame body, a dehydration assembly, and a second driving structure. The dehydration assembly has a dehydration rack, a stop member, and a first driving structure. The dehydration rack is rotatably arranged on the frame body, and a loading member of a mattress is arranged on the dehydration rack, and the loading member has a loading surface. The stop member is arranged above the loading member, the stop member has a stop surface, and an accommodating space of the mattress is formed between the stop surface and the loading surface; the first driving structure is arranged on the dehydration rack and acts on the stop member to drive it to be close to or away from the loading member so as to reduce or enlarge the accommodating space.

Abstract: A method for intelligently measuring vehicle speed based on a binocular stereo vision system includes: training a Single Shot Multibox Detector neural network to obtain a license plate recognition model; calibrating the binocular stereo vision system to acquire parameters of two cameras; detecting the license plates in the captured video frames with the license plate recognition model, locating the license plate position; performing feature point extraction and stereo matching by a feature-based matching algorithm; screening and eliminating the matching point pairs, and reserving the coordinates of the matching point pair closest to the license plate center; performing stereo measurement on the screened matching point pair to get the spatial coordinates of the position; calculating and obtaining the speed of the target vehicle.

Abstract: A patch antenna structure is disclosed. The patch antenna structure includes a radome; a metal substrate disposed on one side of the radome and kept at a distance from the radome, a side wall of the radome facing to the metal substrate connecting with a feeding patch, or a side wall of the metal substrate facing to the radome connecting with a feeding patch; an antenna radiating patch attached to a side wall of the radome facing to the metal substrate, wherein the antenna radiating patch is kept at a certain distance from the metal substrate to maintain the radio frequency characteristics of the patch antenna.

Abstract: A combined bio-artificial liver support system, includes branch tubes that are connected in sequence: a blood input branch tube, an upstream tail end, a first plasma separation branch tube comprising at least a first plasma separator, a non-biological purification branch tube comprising at least a plasma perfusion device and a bilirubin adsorber, a biological purification branch tube comprising at least a hepatocyte culture cartridge assembly, and a plasma return branch tube, a downstream tail end of which is set as a blood output end.

Abstract: Provided is a fusion protein for a biosensing element; the fusion protein includes glucose oxidase (GOD) and a carbohydrate-binding module (CBM); and the GOD is linked to the CBM by means of a linker peptide. The biosensing element specifically binds to cellulose based on CBM.

Abstract: The optical module disclosed herein has a first lens, a second lens and an array lens arranged sequentially along the main optical axis. The first lens shapes a beam along the first direction of the main optical axis. The second lens shapes the beam along the second direction of the main optical axis. The array of array lenses is arranged along the second direction. A laser beam enters the second lens after passing through the first lens. The second lens diffuses the laser beam along the second direction. After the laser beam is converted from a Gaussian distribution to a flat-top distribution in the second direction, the laser beam is emitted through the array lens. The first direction and the second direction are perpendicular to each other.

Abstract: The present invention relates to an illumination module for a microscope apparatus, comprising a plurality of monochromatic sources and a control device, wherein the control device is configured to control states of the plurality of the monochromatic sources, and the control device includes a selecting and switching module which realizes a switch among the plurality of monochromatic sources in response to an operation of the user. The design of the illumination module makes the microscope apparatus compact in structure, highly reliable, convenient in use, and extremely enhancing the work efficiency of the user. The present invention also relates to a method for controlling the illumination module, and a microscope apparatus comprising the illumination module.

Abstract: The invention discloses an optical module and a laser system, and relates to the technical field of optics. The optical module comprises a first light emitting assembly, a second light emitting assembly, and a homogenizing lens group arranged on the light emitting sides of the first light emitting assembly and the second light emitting assembly; Light beams emitted by the first light emitting assembly and the second light emitting assembly are respectively and vertically incident on the light incident side of the homogenizing lens group, and the homogenizing lens group homogenizes and emits the light beams incident by the first light emitting assembly and the second light emitting assembly to form light spots. The optical module and the laser system are small and compact in structure, and can realize diversified forms of output light spots, so that the optical module and the laser system can meet different requirements.

Abstract: A computer-implemented method for graph structure based anomaly detection on a dynamic graph is provided. The method includes detecting anomalous edges in the dynamic graph by learning graph structure changes in the dynamic graph with respect to target edges to be evaluated in a given time window repeatedly applied to the dynamic graph. The target edges correspond to particular different timestamps. The method further includes predicting a category of each of the target edges as being one of anomalous and non-anomalous based on the graph structure changes. The method also includes controlling a hardware based device to avoid an impending failure responsive to the category of at least one of the target edges.

Abstract: The light-absorbing composition according to the present invention includes: a light absorber made of a phosphonic acid represented by the following formula (A) and copper ion; and a curable resin. Alight-absorbing film having desired properties can be provided by curing a coating film of the light-absorbing composition. In the formula (A), R1 to R5 are each independently a hydrogen atom, a halogen atom, a hydroxy group, or a nitro group, and n represents an integer of 1 to 3.

Abstract: Power module includes transformer unit including primary and secondary windings and magnetic core; first and second capacitor units coupled to first terminal of primary winding of transformer unit through first node; first and second external pins respectively coupled to first terminal of first capacitor unit and second terminal of second capacitor unit; first and second switch units coupled to second terminal of primary winding of transformer unit thorough second node; third and fourth external pins respectively coupled to first terminal of first switch unit and second terminal of second switch unit; secondary-side circuit coupled to secondary winding; and fifth and sixth external pins electrically coupled to first and second output terminals of secondary-side circuit, respectively. First external pin is coupled to one of third and fourth external pins selectively.

Abstract: A light-absorbing composition according to the present invention includes: a light absorber; a curable resin; and an alkoxysilane. The alkoxysilane includes a dialkoxysilane. Since the alkoxysilane of the light-absorbing composition includes the dialkoxysilane, desired flexibility is likely to be imparted to a light-absorbing layer owing to an organic functional group of the dialkoxysilane while a strong skeleton having a siloxane bond is formed in the light-absorbing layer.

Abstract: Power module includes transformer unit including primary and secondary windings and magnetic core; first and second capacitor units coupled to first terminal of primary winding of transformer unit through first node; first and second external pins respectively coupled to first terminal of first capacitor unit and second terminal of second capacitor unit; first and second switch units coupled to second terminal of primary winding of transformer unit thorough second node; third and fourth external pins respectively coupled to first terminal of first switch unit and second terminal of second switch unit; secondary-side circuit coupled to secondary winding; and fifth and sixth external pins electrically coupled to first and second output terminals of secondary-side circuit, respectively. First external pin is coupled to one of third and fourth external pins selectively.