Abstract: Described herein are human antibody agents and multi-specific binding agents that specifically bind human CD 19, in particular, native human CD 19. Also provided herein are methods of using the same or compositions thereof for the detection, prevention and/or therapeutic treatment of diseases characterized by CD 19 expression, in particular, B cell lymphomas and leukemias.

Abstract: The disclosure discloses stabilized rice aleurone and a preparation method, using the technology of classifying a rice aleurone layer by a tangential injection airflow impeller classifier combined with an ultrasonic vibrating screen for the first time, and simultaneously uses steam treatment coupled with thermal enzyme inactivation by drum drying as a stabilization method to prepare the stabilized rice aleurone for the first time. The drum drying equipment realizes the two purposes of enzyme inactivation and drying, and the method has the advantages of short process flow, simple equipment, high utilization rate, small floor space, low investment, low energy consumption and no pollution, and is suitable for industrial promotion. The stabilized rice aleurone has high nutritional value, is rich in functional ingredients, and can be used as a raw material for functional food development in industrial production and food applications.

Abstract: Provided herein are methods of treating B7-H1-expressing tumors comprising administering an effective amount of MEDI4736 or an antigen-binding fragment thereof.

Abstract: A semiconductor device structure is provided. The semiconductor device structure includes a chip structure including a substrate and a wiring structure over a first surface of the substrate. The semiconductor device structure includes a first seed layer over the wiring structure, a first inner wall of the first enlarged portion, and a second inner wall of the neck portion. The semiconductor device structure includes a second seed layer over a second surface of the substrate, a third inner wall of the second enlarged portion, and the first seed layer over the second inner wall of the neck portion. The second seed layer is in direct contact with the first seed layer.

Abstract: An outdoor moving device includes a main body, a first energy storage device, a second energy storage device, and a connection assembly. The first energy storage device is capable of supplying power to the outdoor moving device and includes at least one first energy storage unit. The second energy storage device is capable of supplying power to the outdoor moving device and includes at least one second energy storage unit. The connection assembly is used for mounting the second energy storage device to the main body. The first energy storage device is detachably mounted to the main body, the first energy storage device is detachable from the main body to supply power to another power tool, the first energy storage unit includes a first positive electrode made of a first material, and the second energy storage unit includes a second positive electrode made of a second material.

Abstract: A method of treating an aortopathy is disclosed, including identifying a subject having or at risk of developing the aortopathy and reducing the expression of and/or activity of gasdermin D (GSDMD) in the subject. The method may include administering to the subject an effective amount of a GSDMD inhibitor. The GSDMD inhibitor may reduce the expression of GSDMD in the subject and/or may reduce the activity of GSDMD in the subject.

Abstract: Provided is a cup lid with a retractable drinking spout and drinking cup, including a cup lid body provided with a through hole; a base fixedly connected to the cup lid body and located at a bottom of the through hole; a drinking spout movably installed in the through hole and capable of stretching out from a top of the through hole or retracting into the through hole; and an elastic part arranged in the through hole and having one end in butting connection with the base and the other end in butting connection with the drinking spout, the elastic part pushing the drinking spout to stretch out when popping up, and the elastic part being compressed to accumulate force when the drinking spout retracts.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for realizing a multimodal image classifier. In an aspect, a method includes, for each image of a plurality of images: processing the image by a textual generator model to obtain a set of phrases that are descriptive of the content of the image, wherein each phrase is one or more terms, processing the set of phrases by a textual embedding model to obtain an embedding of predicted text for the image, and processing the image using an image embedding model to obtain an embedding of image pixels of the image. Then a multimodal image classifier is trained on the embeddings of predicted text for the images and the embeddings of image pixels for the images to produce, as output, labels of an output taxonomy to classify an image based on the image as input.

Abstract: This disclosure relates to an organic electroluminescent structure and a display device. The organic electroluminescent structure includes a base substrate; a passivation protective layer provided at a side of the base substrate, in which the passivation protective layer is provided with a plurality of inner cutting portions arranged at intervals at a side facing away from the base substrate, each of the inner cutting portions has a first surface towards the base substrate and a second surface away from the base substrate, an orthographic projection of the first surface on the base substrate is within an orthographic projection of the second surface on the base substrate, and a groove is provided between two adjacent inner cutting portions and is formed as an inner cutting structure; an anode layer including a plurality of anodes arranged at intervals; an organic light-emitting functional layer having a hole injection layer.

Abstract: Methods and structures of a three-dimensional memory device are disclosed. In an example, the disclosed method comprises forming a plurality of dielectric stacks stacked on one another over a substrate to create a multiple-stack staircase structure. Each one of the plurality of dielectric stacks comprises a plurality of dielectric pairs arranged along a direction perpendicular to a top surface of the substrate. The method further comprises forming a filling structure that surrounds the multiple-stack staircase structure, forming a semiconductor channel extending through the multiple-staircase structure, wherein the semiconductor channel comprises unaligned sidewall surfaces, and forming a supporting pillar extending through at least one of the multiple-staircase structure and the filling structure, wherein the supporting pillar comprises aligned sidewall surfaces.

Abstract: The photovoltaic system includes an inverter, a fan, and a controller. A photovoltaic string and a direct current bus capacitor are connected between a positive input end and negative input end of the inverter. The controller receives a fast shutdown instruction and sends a drive signal to a switching transistor in the inverter, so that the switching transistor performs a switching action under the action of the drive signal, and the switching transistor consumes electric energy during the switching action; or the controller turns on the fan after receiving the fast shutdown instruction to consume electric energy by using the fan; or the controller may send the drive signal to the switching transistor and also control the fan to be turned on, so that both the switching transistor and the fan consume electric energy.

Abstract: Disclosed are a target LED chip with a reflective layer and a manufacturing method. The method comprises providing a target substrate to a bottom of an initial LED chip, to obtain a first LED chip; depositing a first target liquid onto a top surface of the first LED chip to form a target protective layer, so as to obtain a second LED chip; etching the second LED chip from the target protective layer, to obtain a third LED chip; treating the third LED chip according to a first target method to form reflective layers, so as to obtain a fourth LED chip; and removing top reflective layers, second side wall reflective layers and first sub-protective layers of the plurality of second LED sub-units, to obtain the target LED chip comprising the plurality of target LED sub-units and the target substrate.

Abstract: The present application provides a semiconductor device and the method of making the same. The method includes recessing a fin extending from a substrate, forming a base epitaxial feature on the recessed fin, forming a bar-like epitaxial feature on the base epitaxial feature, and forming a conformal epitaxial feature on the bar-like epitaxial feature. The forming of the bar-like epitaxial feature includes in-situ doping the bar-like epitaxial feature with an n-type dopant at a first doping concentration. The forming of the conformal epitaxial feature includes in-situ doping the conformal epitaxial feature with a second doping concentration greater than the first doping concentration.

Abstract: Systems and methods of generating a security key for an integrated circuit device include generating a plurality of key bits with a physically unclonable function (PUF) device. The PUF can include a random number generator that can create random bits. The random bits may be stored in a nonvolatile memory. The number of random bits stored in the nonvolatile memory allows for a plurality of challenge and response interactions to obtain a plurality of security keys from the PUF.

Abstract: Gas bubble migration can be managed in liquids. In one example, a system can execute wellbore-simulation software to simulate changes in gas dissolution in a liquid over time. This may involve dividing the wellbore into segments spanning from the well surface to the downhole location, each segment spanning a respective depth increment between the well surface and the downhole location. Next, for each time, the system can determine a respective multiphase-flow regime associated with each segment of the plurality of segments based on a simulated pressure level, a simulated temperature, a simulated pipe eccentricity, and a simulated fluid velocity at the segment. The system can also determine how much of the gas is dissolved in the liquid at each segment based on the respective multiphase-flow regime at the segment. The system can display a graphical user interface representing the gas dissolution in the liquid over time.

Abstract: An electronic component assembly having thermal pads with thermal vias coupling an image sensor and a camera board fab is provided for heat dissipation. The electronic component assembly can include: a circuit board having at least one thermal pad disposed on a top surface of the circuit board; and an image sensor disposed on the top surface of the circuit board, having at least one conductive pad disposed at at least one corner of the image sensor. The at least one thermal pad is coupled to the at least one conductive pad of the image sensor and the at least one thermal pad is formed with a plurality of first thermal vias penetrating the thermal pad and the circuit board for transfer of heat of the image sensor.

Abstract: Methods and systems are provided for improving user authentication and access control by a network file system service in a multi-tenant public cloud environment by receiving a request for a connection to a file system from a file system client (client), sending an identification request for identification authentication of the client to a control system, receiving a response from the control system, establishing the connection to the file system upon determining that the connection to the file system is allowed based on cloud tenant information associated with the client, receiving an attempt to access the file system from the client by a sub-user, authenticating the sub-user based on the cloud tenant information, issuing a security token including a globally unique sub-user identifier of the sub-user, and using the security token to determine access rights of the sub-user to the file system for a subsequent request.

Abstract: Provided is an automatic air-release box lid, including: a box lid body provided with an air hole, the air hole being configured as a through-hole structure, openings at two ends of the air hole being located on an upper surface and a lower surface of the box lid body respectively; and a fastening lug having a rotating shaft part by which the fastening lug is hinged to the upper surface of the box lid body, the rotating shaft part and one opening of the air hole being arranged corresponding to each other and one above the other, the rotating shaft part having a blocking surface. Further provided is a preservation box, including: an automatic air-release box lid and a box body. The box lid is fitted to cover the box body.

Abstract: A method includes forming a first low-dimensional layer over an isolation layer, forming a first insulator over the first low-dimensional layer, forming a second low-dimensional layer over the first insulator, forming a second insulator over the second low-dimensional layer, and patterning the first low-dimensional layer, the first insulator, the second low-dimensional layer, and the second insulator into a protruding fin. Remaining portions of the first low-dimensional layer, the first insulator, the second low-dimensional layer, and the second insulator form a first low-dimensional strip, a first insulator strip, a second low-dimensional strip, and a second insulator strip, respectively. A transistor is then formed based on the protruding fin.