Abstract: A technique, and its applications, for high resolution, rapid, and simple nanopatterning. The general method has been demonstrated in several forms and applications. One is patterning nanophotonic structures at an optical fiber tip for refractive index sensing. Another is patterning nanoresonator structures on a sensor substrate for plasmonic effect related detection of VOCs. In the latter example, a graphene oxide coated plasmonic crystal as a gas sensor capable of identifying different gas species using an array of such structures. By coating the surface of multiple identical plasmonic crystals with different thicknesses of Graphene-Oxide (GO) layer, the effective refractive index of the GO layer on each plasmonic crystal is differently modulated when exposed to a specific gas. Identification of various gas species is accomplished using pattern recognition algorithm.

Abstract: The invention provides a controlled release oral solid formulation comprising (a) a controlled release component comprising core comprising levodopa and/or an ester of levodopa or salts thereof, wherein the core is coated with a layer of a muco-adhesive polymer and externally coated with a layer of an enteric coated polymer; and (b) a decarboxylase inhibitor component.

Abstract: A method, system, and/or computer program product adjust values of a plurality of conditions. A processor receives a user input, which is a movement across a user interface. A tendency of the movement, which describes a direction and velocity of the movement, is determined. According to the tendency of the movement, a processor adjusts a value of at least one of the plurality of conditions by using a plurality of graphs representing the plurality of conditions, where the plurality of conditions describe search criteria, and where the user input describes the search criteria.

Abstract: There is provided an imidazole derivative, wherein the structural formula of the imidazole derivative is as represented by formula There is further provided a material containing the imidazole derivative and an organic light-emitting device containing the imidazole derivative. The imidazole derivative has an excellent carrier transport capacity, and the organic light-emitting device produced by using the material has obviously reduced starting voltage and improved luminous efficiency and luminance; and due to the features such as relatively good film-forming performance and simple material synthesis and purification methods which are applicable to mass production, the imidazole derivative is an ideal option for an electron transport material of organic light-emitting devices.

Abstract: A modular quality improvement process and quality improvement system for high density coal measures oil shale. The process comprises: performing separation on the material with a particle size larger than 13 mm by an air dense medium fluidized bed, performing separation on the material with a particle size equal to or less than 13 mm and larger than 6 mm by an air dense medium fluidized bed, performing separation on the material with a particle size equal to or less than 6 mm and larger than 3 mm by a vibrated dense medium fluidized bed, and performing separation on the material with a particle size equal to or less than 3 mm by a vibrated fluidized bed, and recovery of a medium by magnetic separation for use as a circulating medium.

Abstract: A process for optimizing the design of a semi-open centrifugal pump impeller involves the steps of, reducing the number of long blades and adding a medium length splitter blade and a short length splitter blade having varying circumferential distances between any two optimized long blades. Each medium length and short length splitter blade have the same outlet position, profile and thickness as the optimized long blade; however, the medium length and short length splitter blades have different inlet positions relative to the optimized long blade. The long blade, medium length splitter blade and short length splitter blade are arranged in circumferential sequence along the direction of rotation of the impeller. This optimization improves various problems arising from the original semi-open centrifugal pumps, including low efficiency, significant loss at the inlet, inlet cavitation, separation of boundary layers at the blade inlets, narrow lift range of the dead point and excessive noise.

Abstract: The present disclosure relates to a belt driven system. The belt driven system may include a master pulley, a slave pulley, a belt around the master pulley and the slave pulley, a tension pulley configured to tension the belt, and a position adjusting device configured to automatically adjust a position of the tension pulley based on an interaction of the tension pulley and the belt.

Abstract: An electrophoresis chip-based setup for detection of different ions in buffer solution. The device is able to differentiate ions in, e.g., real soil or other solutions, and to detect concentration of a specific ion in the solution. Fabrication of the electrophoresis chip can use a soft lithography based molding process. The chip can be made out of PDMS on a glass substrate where on-chip valves were used to control timing of injecting sample and buffer solutions. Detection electrodes are used to detect the presence of ions over a period of several minutes. A controllable high voltage power supply system and related signal acquisition, processing and detection setup can be implemented with the sensor in a system. A microfluidic system for automated collection of soil sample through a porous ceramic and using vacuum suction can be used.

Abstract: The invention provides a controlled release oral solid formulation comprising (a) a controlled release component comprising core comprising levodopa and/or an ester of levodopa or salts thereof, wherein the core is coated with a layer of a muco-adhesive polymer and externally coated with a layer of an enteric coated polymer; and (b) a decarboxylase inhibitor component.

Abstract: A disclosed system quantifies the power distribution of a wireless signal within a constrained environment using non-sequential ray tracing. For each ray, one or more ray-reflecting surface is prescreened to identify collision-eligible surfaces and identify a collision surface from the collision-eligible surfaces, wherein the collision surface is the first ray-reflecting surface that a ray collides with. A power distribution component, indicating the position and power of a ray at a particular elevation within the environment, is added to a cumulative power distribution. If a reflected ray corresponding to each collision is calculated and satisfies ray eligibility conditions, a collision surface may be determined for the reflected ray. Collision surfaces may be identified by evaluating a target function for a number of ray positions, where the target function evaluates to zero when displacement between the ray and the ray-reflecting surface is zero.

Abstract: A disclosed system quantifies the power distribution of a wireless signal within a constrained environment using non-sequential ray tracing. For each ray, one or more ray-reflecting surface is prescreened to identify collision-eligible surfaces and identify a collision surface from the collision-eligible surfaces, wherein the collision surface is the first ray-reflecting surface that a ray collides with. A power distribution component, indicating the position and power of a ray at a particular elevation within the environment, is added to a cumulative power distribution. If a reflected ray corresponding to each collision is calculated and satisfies ray eligibility conditions, a collision surface may be determined for the reflected ray. Collision surfaces may be identified by evaluating a target function for a number of ray positions, where the target function evaluates to zero when displacement between the ray and the ray-reflecting surface is zero.

Abstract: The invention relates to a rapidly disintegrating oral dosage form that contains a drug/polymer solid solution and methods of using the oral dosage form.

Abstract: Systems, methods, and apparatus for large scale, high throughput phenotyping of items including plants to derive environment/genetics correlations based on controlled variation of environment. Spatial and temporal resolution is improved by an integrated system that can use space efficiently yet concurrently process a large number of replicates but in varying environments. This is accomplished by using an array of miniature greenhouses, each in communication with one or more generators or regulators of an environmental factor that can be independently supplied and controlled to each miniature greenhouse. The controller also controls acquisition of data from each greenhouse as well as processing of that data into phenomic/genomic correlations.

Abstract: A system, method, and apparatus for the fermentation of a beverage by use of continuous flow is provided. The fermented beverage can be any of a wine, beer, mead, ale, soda, cider, or other. The invention provides for small-scale fermentation that can be done in a much shorter time than previous batch fermentations. The small-scale and shortened time allows for variables to be introduced and tested to produce new varieties, flavors, qualities, and other combinations that are inputs of the fermented beverage.

Abstract: The invention provides a controlled release oral solid formulation comprising (a) a controlled release component comprising core comprising levodopa and/or an ester of levodopa or salts thereof, wherein the core is coated with a layer of a muco-adhesive polymer and externally coated with a layer of an enteric coated polymer; and (b) a decarboxylase inhibitor component.

Abstract: Methods, systems, and apparatus for high-resolution patterning of various substrates with functional materials, including nanomaterials. A technique of preparing a patterned substrate in a high-resolution mold for stick and transfer process is disclosed with promotes integrity of the high-resolution pattern onto the substrate. One example of a substrate is an adhesive tape. The transferred pattern(s) are scalable and can be implemented in different fabrication processes. One example is a roll-to-roll processes. In one embodiment, the transferred pattern comprises nanomaterials and the substrate comprises a flexible substrate for use in flexible and conformal assemblies for a wide variety of applications including, but not limited to, electrical-based sensors on non-planar inanimate surfaces, plant body surface, or human or animal skin.

Abstract: A gas-liquid-solid three-phase slurry bed industrial reactor capable of achieving continuous operation comprises an inlet gas distribution component composed of a false bottom and inlet gas distribution tubes, one or more layers of heat exchange tube components used for heating/cooling the bed, one or more layers of liquid-solid separator components capable of being cleaned automatically, an outlet gas-liquid-solid entrainment separation component located in the upper portion of the interior of the reactor and used for removing liquid foam and solid entrainments, a plurality of layers of solid concentration uniform distribution devices used for reducing the catalyst concentration gradient and the inlet-outlet temperature difference of the reactor, a flow guiding device located on a component support beam and used for preventing catalyst accumulation, and auxiliary systems including a filter-backflush system and a washing system.

Abstract: Embodiments of optical fiber may include cladding features that include a material (e.g., fluorine-doped silica glass) that may produce a very low relative refractive index difference with respect to cladding material in which the cladding features are disposed. This relative refractive index difference may be characterized by (n1?n2)/n1, where n1 is the index of refraction of the cladding material in which the cladding features are included, and n2 is the index of refraction of the cladding features. In certain embodiments, the relative refractive index difference may be less than about 4.5×10?3. In various embodiments, the configuration of the cladding features including, for example, the size and spacing of the cladding features, can be selected to provide for confinement of the fundamental mode yet leakage for the second mode and higher modes, which may provide mode filtering, single mode propagation, and/or low bend loss.

Abstract: Holey fibers provide optical propagation. In various embodiments, a large core holey fiber comprises a cladding region formed by large holes arranged in few layers. The number of layers or rows of holes about the large core can be used to coarse tune the leakage losses of the fundamental and higher modes of a signal, thereby allowing the non-fundamental modes to be substantially eliminated by leakage over a given length of fiber. Fine tuning of leakage losses can be performed by adjusting the hole dimension and/or spacing to yield a desired operation with a desired leakage loss of the fundamental mode. Resulting holey fibers have a large hole dimension and spacing, and thus a large core, when compared to traditional fibers and conventional fibers that propagate a single mode. Other loss mechanisms, such as bend loss and modal spacing can be utilized for selected modes of operation of holey fibers.

Abstract: Disclosed is an information query method and apparatus. The method includes: obtaining a query word input by a user through a terminal, identifying a target entity in the query word and determining a globally unique identifier (GUID) of the target entity for a knowledge map; determining a target entity type corresponding to the target entity according to a corresponding relationship between an entity and the entity type. The target entity type is used to indicate the target attribute and/or target entity relationship to be queried of the target entity; according to the GUID and an identifier of the target attribute and/or an identifier of the target entity relationship, querying an attribute value and/or a related entity corresponding to the identity of the target attribute and/or an identifier of the target entity relationship in the knowledge map; returning a search result to the terminal.