Abstract: An assembled jade activation material is assembled and synthesized by the sol-gel method, and contains 55-59% tetraethyl orthosilicate, 4-8% calcium nitrate tetrahydrate, 26-30% magnesium nitrate hexahydrate, 1-8% zinc nitrate, 0-3% yeast selenium, 0-1% manganese nitrate and 0-1% copper nitrate by molar ratio, and the sum of the mole percentages of each component is 100%. The assembly method draws on the main components of natural jade materials that exert their effects, and synthesizes the assembling jade activation materials through self-assembly of sol-gel technology, uniquely increases silicon, calcium, magnesium ions, etc., and adjusts the amount of trace elements according to needs, adding zinc, selenium, manganese, copper and other elements.

Abstract: A method for improving a skin condition of a subject in need thereof includes administering to the subject a composition including a bioactive compound. The bioactive compound is a peptide, and includes at least one amino acid sequence as set forth in SEQ ID NO: 1 to SEQ ID NO: 11. Each of the amino acid sequence is a peptide of fish skin.

Abstract: The present disclosure provides an optical sensor, a manufacturing method thereof, a display device, and a display apparatus, and relates to the display technology. The optical sensor includes a thin film transistor and a PIN diode on a surface of a drain of the thin film transistor. A material of a P region of the PIN diode, a material of an I region of the PIN diode, and a material of an N region of the PIN diode are oxides. Since the PIN diode is made of oxides rather than amorphous silicon, hydrogen is not introduced. Therefore, the performance of the thin film transistor will not be affected, thereby achieving the improvement of the performance of the display device and the display effect.

Abstract: Disclosed are a compound of formula I as a toll-like receptor 7 (TLR7) agonist or a pharmaceutically acceptable salt thereof for treating colorectal cancer, a pharmaceutical combination for treating colorectal cancer comprising the TLR7 agonist and a tyrosine kinase inhibitor, and the use of the compound of formula I or the pharmaceutically acceptable salt thereof and the pharmaceutical combination for treating colorectal cancer.

Abstract: A method for treating eye inflammation by using an anti-inflammatory composition is provided. The bioactive compound in the anti-inflammatory composition is a peptide having an amino acid sequence as set forth in SEQ ID NO.: 1. The amino acid sequence is a peptide fragment derived from cowhide. The composition may be administered to the eye of a human subject for reducing the expression of vascular endothelial growth factor A (VEGFA) gene, interleukin-1 beta (IL-1?) gene, and/or interleukin-8 (IL-8) gene.

Abstract: Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.

Abstract: The present invention relates to the field of medical biology, and discloses a high-resolution crystal structure of a complex of PD-L1-blocking heavy-chain single-domain antibody KN035 binding with PD-L1, and the use of the crystal structure. The invention also relates to novel PD-L1 binding polypeptides or compounds developed based on the crystal structure and uses thereof.

Abstract: A non-invasive method for measuring the motion characteristics of myocardial tissue includes transmitting a plurality of generated synchronous orthogonal, phase controllable and adjustable alternating currents with different frequencies to an organism so as to generate a plurality of synchronous periodic AC voltage signals with different frequencies; receiving the periodic AC voltage signals modulated by changes in the organism's heart tissue to obtain the organism's frequency responses; calculating resistances and capacitances of the heart tissue according to the frequency responses; estimating motion characteristics of myocardial tissue according to the resistances and the capacitances. By means of introducing the average longitudinal length of the myocardial cells, and calculating changes in the average longitudinal length of the myocardial cells according to the capacitances, the overall longitudinal elasticity of the heart is described.

Abstract: This application relates to a technique that enables efficient indexing and querying of a set of documents stored at a computing device. The technique assigns a rank to each term of a set of terms based on a historical occurrence of each term to produce a set of ranked terms. The technique also creates subsets that include terms from the set of ranked terms to produce ranked term subsets that are encoded in accordance with an allocated bit size. The technique generates an index for each document of the set of documents through: (1) the identification of the ranked term subsets within the document, (2) the generation of arrays to store each ranked term subset identified within the document, and (3) the embedding of metadata within the document. The metadata includes: (i) one or more arrays and (ii) one or more counts corresponding to each array.

Abstract: The present disclosure discloses a pixel circuit, a driving method thereof, a display panel, and a display device, which belong to the technical field of display. The pixel circuit includes a data writing sub-circuit, a compensation sub-circuit, a storage sub-circuit, and a driving sub-circuit. Since the compensation sub-circuit may output a first power signal to a first node, the storage sub-circuit may adjust the potential of a second node according to the potential of the first node.

Abstract: An organic light emitting diode display substrate includes a light emitting unit layer, a first band gap layer and a color conversion layer. The first band gap layer and the color conversion layer are on a light exit path of the light emitting unit layer. The light emitting unit layer includes first, second and third light emitting units periodically arranged on a driving substrate and emitting light of a first color. The color conversion layer converts a part of the light of the first color into light of a second color and a third color. The first band gap layer is between the light emitting unit layer and the color conversion layer. The first band gap layer transmits the light of the first color in a light exit direction, and reflects the light of the second color and the light of the third color.

Abstract: Provided herein are KRAS G12C inhibitors, such as composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.

Abstract: Embodiments of the present disclosure provide a thin film transistor, a method of manufacturing the same, and a display device. The thin film transistor includes a metal conductive pattern layer, an interlayer insulating layer, and a metal oxide layer; and the metal conductive pattern layer includes: a light shielding pattern, a source signal line, and/or a drain signal line; the metal oxide layer includes: a source electrode, a drain electrode, and an active layer. An orthographic projection of the active layer on the base substrate has an overlapping region with that of the light shielding pattern; the source electrode extends through the interlayer insulating layer to connect to the source signal line, and/or the drain electrode extends through the interlayer insulating layer to connect to the drain signal line.

Abstract: Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.

Abstract: A system, method and computer readable storage medium are disclosed to provide dynamic network resource management in a telecommunications network where at least a portion of the network resources are located at an edge of the telecommunications network. The capacity available, the aggregate demand of resources at a given time, and the cost of the network resource demanded as well as each customers upper price limit may be considered and adjusted in real-time by different network resource allocation models.

Abstract: The present disclosure provides a display device, including: a display panel, a main circuit board, and a plurality of chip-on-films bonded between the display panel and the main circuit board. The wiring area is provided with a plurality of first binding regions; the plurality of first binding regions are distributed along the wiring area. The main circuit board is provided with a plurality of second binding regions which are corresponding to the first binding regions in a one-to-one manner. A shape of the main circuit board is the same as a shape of the wiring area. A first end of each chip-on-film is bonded to one corresponding first binding region; a second end of each chip-on-film is bonded to one corresponding second binding region.

Abstract: The pixel circuit includes a data-writing module, a drive module, a storage module, a first light emission control module, a second light emission control module, a light-emitting module and a first initialization module. A first terminal of the first initialization module is electrically connected to a second light emission control signal input terminal, a second terminal of the first initialization module is electrically connected to a control terminal of the drive module; or the pixel circuit includes an initialization voltage input terminal, the first terminal of the first initialization module is electrically connected to the initialization voltage input terminal, the second terminal of the first initialization module is electrically connected to the control terminal of the drive module. The first initialization module is configured to initialize the control terminal of the drive module under a control of a control signal input into a control terminal of the first initialization module.

Abstract: A fan dynamic pressure structure having a plastic frame integrally formed around an oil-containing sintered metal powder bearing includes an oil-containing sintered metal powder bearing, a plastic frame having a middle tube integrally formed around a peripheral of a bushing body of the oil-containing sintered metal powder bearing, a blade assembly having an axial shaft penetrating through a shaft hole of the oil-containing sintered metal powder bearing, the axial shaft protruding downwardly and having an annular groove, and an annular dynamic pressure piece having an insertion hole and an annular body surrounding the insertion hole. The insertion hole is engaged with the annular groove of the fan assembly, the annular body has a plurality of curved radial dynamic pressure ditches on a surface adjacent to the oil-containing sintered metal powder bearing, of the annular body.

Abstract: Provided herein are methods of using KRAS G12C inhibitors. These methods of using the inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.

Abstract: The embodiment of the present disclosure discloses an array substrate, a fabrication method thereof, and a display device. The array substrate includes: a base substrate and a plurality of pixel units on the base substrate, wherein the pixel unit includes a plurality of sub-pixels; and the sub-pixel includes an electroluminescent component, a pixel circuit and a photo detection circuit; the pixel circuit includes a drive transistor for driving the electroluminescent component to emit light, and the drive transistor is a low temperature poly-si thin film transistor; and the photo detection circuit includes a detection switch transistor and a PIN-type photodiode, and the detection switch transistor is a metal oxide transistor.