Abstract: There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compound and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the invention.

Abstract: Described herein are compounds and compositions for electrolytes based on bidentate and monodentate fluorinated alcohols. Also described are batteries that include the compounds and electrolytes described herein.

Abstract: There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the invention.

Abstract: There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the invention.

Abstract: The present invention provides compounds of formula (I), formula (II) or formula (III), wherein all of the variables are as defined herein. These compounds are inhibitors of indoleamine 2,3-dioxygenase (IDO), which may be used as medicaments for the treatment of proliferative disorders, such as cancer, viral infections and/or autoimmune diseases.

Abstract: In one aspect, a method of forming a semiconducting device can comprise forming, on a substrate surface, a stack comprising semiconductor material sheets and a bottom semiconductor nanosheet; forming a trench through the stack vertically down through the bottom semiconductor nanosheet, thereby separating the stack into two substacks; selectively removing the bottom semiconductor nanosheet, thereby forming a bottom space extending under the substacks; and filling the bottom space and the trench with a dielectric material to provide a bottom isolation and formation of a dielectric wall between the substacks.

Abstract: A method implemented by a network device in a communication network is provided. The network device is operable to communicate with a User Equipment UE and a Narrow Band Internet Of Things NB-IoT terminal device in the communication network. Said method may comprise configuring NB-IoT Physical Resource Blocks PRBs. Said method may further comprise when scheduling said UE, if said configured NB-IoT PRBs have not been allocated to said NB-IoT terminal device and if available PRBs other than said configured NB-IOT PRBs are not enough for said UE, attempting to allocate said configured NB-IoT PRBs for said UE. A network device performing said method is also provided. Further, a communication network comprising said network device is also provided.

Abstract: A train, comprising a train formation consisting of a head car, a power car and an intermediate car, end walls of the head car, power car and intermediate car having thereon oppositely disposed connectors 2 extending perpendicular to a direction of travel of the train; all connectors 2 on the end walls of the train are connected by means of wiring; the head car, power car and intermediate car connect electric power wiring of the whole train by means of the connectors when in any formation state; the train has disposed thereon two parallel power supply wires penetrating the entire train and multiple auxiliary power supply systems. The present invention can decrease different voltage standard conversion equipment of a multiple unit, lowering in-vehicle equipment costs.

Abstract: The disclosure discloses a phosphorus-nitrogen-zinc two-dimensional supramolecular coated molybdenum disulfide hybrid flame retardant and application thereof, and belongs to the technical field of halogen-free flame retardant. Components of the phosphorus-nitrogen-zinc two-dimensional supramolecular coated molybdenum disulfide hybrid material in the disclosure include, by weight, 1-2 parts of molybdenum disulfide, 1-1.5 parts of zinc salt, 5-8 parts of a nitrogen-containing compound and 5-10 parts of a phosphorus-containing compound. As a flame retardant, the hybrid material of the disclosure effectively exerts an organic-inorganic synergistic flame retardant effect; the flame retardant efficiency of molybdenum disulfide is improved; the addition amount of the flame retardant in a matrix is reduced; the mechanical properties of the matrix can be improved at the same time; and the material has a very good application prospect.

Abstract: Disclosed is a method for preparing self-dispersing nano carbon black based on a thiol-ene click reaction. A sol-gel technique is used to graft a coupling agent containing a carbon-carbon double bond onto the surface of the carbon black, and a functional molecular chain is grafted onto the surface of the carbon black by a thiol-ene click reaction with a mercapto compound. The self-dispersing nano carbon black is obtained after centrifugation, washing and drying. The method is simple and easy to operate, has a high grafting rate, and can prepare self-dispersing nano carbon black adaptable to different systems by selecting mercapto compounds with different functional groups.

Abstract: The invention discloses a preparation method of pH/reduction responsive polyamino acid zwitterionic nanoparticles, which belongs to the technical field of polymer synthesis and biomedical materials. In the invention aliphatic amines are used to initiate ring-opening polymerization of ?-benzyl-L-glutamate-N-carboxylic anhydride, and the obtained poly(?-benzyl-L-glutamate) reacts with L-lysine to form azwitterionic polymer. The zwitterionic polymer is crosslinked by cysteamine, producing pH/reduction responsive polyamino acid zwitterionic nanoparticles after purification. The nanoparticles are pH responsive and resistant to non-specific protein adsorption. Because cysteamine contains disulfide bonds, the nanoparticles have sensitive reductive responsiveness and can load anticancer drugs for controlled release at the target site of cancer.

Abstract: A method for making xanthan gum copolymer nanomicelles comprising: 1) degrading xanthan gum in aqueous solution to obtain degraded xanthan gum; 2) preparing xanthan gum bromide from the degraded xanthan gum; 3) preparing xanthan gum copolymer from the xanthan gum bromide and 4) making the gum copolymer nanomicelles from the xanthan gum copolymer. The xanthan gum copolymer nanomicelles have good morphological regularity, good biocompatibility and stable performance as an anticancer drug carriers.

Abstract: The present invention discloses modified epoxy acrylates and the solder resist containing the epoxy modified acrylates, belonging to the synthetic resin field. In this invention, modified epoxy acrylates are prepared by introducing long fatty hydrocarbon chain as the branched chain into the carboxylated epoxy acrylates. The as-prepared solder resist containing this modified epoxy acrylates maintains the excellent property of photosensitive solder resist such as good adhesion, hardness, solvent resistance and weather resistance which facilities sensitivity and alkaline development during exposure simultaneously. This has led to good water resistance, electrical insulation of the cured products. Furthermore, the cured product also shows good flexibility which improves its application in photosensitive imaging ink materials.

Abstract: A humidifier includes a shell, a fixing bracket, an atomizer, and a control circuit assembly, and the fixing bracket is disposed in a containing cavity of the shell and divides the containing cavity into a first isolating cavity and a second isolating cavity opposite to each other; the control circuit assembly is disposed in the first isolating cavity, and a solution is contained in the second isolating cavity; the atomizer is positioned in the solution of the second isolating cavity and electrically connected to the control circuit assembly. The control circuit assembly controls the atomizer to atomize the solution.

Abstract: The present invention discloses modified epoxy acrylates and the solder resist containing the epoxy modified acrylates, belonging to the synthetic resin field. In this invention, modified epoxy acrylates are prepared by introducing long fatty hydrocarbon chain as the branched chain into the carboxylated epoxy acrylates. The as-prepared solder resist containing this modified epoxy acrylates maintains the excellent property of photosensitive solder resist such as good adhesion, hardness, solvent resistance and weather resistance which facilities sensitivity and alkaline development during exposure simultaneously. This has led to good water resistance, electrical insulation of the cured products. Furthermore, the cured product also shows good flexibility which improves its application in photosensitive imaging ink materials.

Abstract: Embodiments described herein provide a solution for optimizing a generating of query search results. A filtering search term (e.g., a search term that is used in a query to perform filtering aggregations of the query search results) is identified. A filtering bitmap that has a plurality of mapped locations corresponding to data values for the filtering search term is created. As a data value in the filtering search term is encountered during a scan of the query search results, the corresponding mapped location is updated. Each mapped location in the filtering bitmap is read to determine whether the value corresponding to the mapped location satisfies the filtering aggregation. The filtering aggregation can then be performed (e.g., prior to any grouping aggregation) by removing any of the query search results determined, based on the filtering bitmap, as having data values for which the filtering aggregation is not satisfied.

Abstract: A method and system for true product word recognition using a computing device. The method includes: obtaining title words from titles of products; determining word vectors based on a word matrix, where the word matrix is constructed based on a number of cooccurrence of each of the title words and all the other title words; determining title vectors based on a title matrix, where the title matrix is constructed based on the number of cooccurrence of each of the title words and all the other title words, and the title words in each of the titles; calculating scores for the title words in corresponding one of the titles based on the corresponding word vector and title vector; and recognizing true product words of the corresponding one of the titles based on the scores.

Abstract: A localized topical hyperbaric therapeutic instrument, comprising: a primary airbag, which is a chamber with an opening at an end; an oxygen generating device, which comprises an oxygen generator and a first pressure controller, wherein the oxygen generator has an oxygen outlet which communicates with the primary airbag through a first air inlet line and supplies oxygen into the primary airbag, and wherein the first pressure controller controls an amount of oxygen supplied to the primary airbag by the oxygen generator; a massage device; a heating piece, which is arranged in the primary airbag and generates heat; a treatment unit, which is arranged in the primary airbag in a detachable manner, disposed at a position corresponding to the heating piece, and comprises medical ingredients which are volatile upon heating.

Abstract: Provided herein are techniques for processing a database query aggregating data. Data tuples of a database object each including a grouping element and a data element are analyzed to determine a length of the data element for each data tuple. A plurality of tables each accommodate a successively greater length for the data element. A corresponding table of the plurality of tables to store each data tuple is determined based on the length of the data element of that data tuple relative to the accommodated lengths of the plurality of tables. Each data tuple in the determined corresponding table is stored to group the data tuples within each of the plurality of tables based on the grouping element, and an indication of corresponding tables containing members for each group is provided. The groups are combined across the plurality of tables to aggregate the data tuples for a database query.