Patents by Inventor Lisa M. Schultze

Lisa M. Schultze has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tetracyclic compounds as PDE5-inhibitors
    Patent number: 7105506
    Abstract: Compounds of structural formula (I) and use of the compounds and salts and solvates thereof, as therapeutic agents.
    Type: Grant
    Filed: May 2, 2002
    Date of Patent: September 12, 2006
    Assignee: Lilly Icos LLC
    Inventors: Mark W. Orme, Jason S. Sawyer, Lisa M. Schultze
  • Pyrazino [1'2':1,6 ] pyrido [3, 4-b] indole-1,4-dione derivatives
    Patent number: 7098209
    Abstract: Compounds of the general structural formula (I), and use of the compounds and salts and solvates thereof, as thereapeutic agents.
    Type: Grant
    Filed: April 15, 2002
    Date of Patent: August 29, 2006
    Assignee: Lilly Icos LLC
    Inventors: Mark W. Orme, Jason S. Sawyer, Lisa M. Schultze
  • Fused heterocyclic derivatives as phosphodiesterase inhibitors
    Patent number: 7034027
    Abstract: Compounds of general structural formula (I) and use of the compounds and salts and solvates thereof, as therapeutic agents.
    Type: Grant
    Filed: July 9, 2001
    Date of Patent: April 25, 2006
    Assignee: Lilly Icos LLC
    Inventors: Mark W. Orme, Jason Scott Sawyer, Lisa M. Schultze
  • Carboline derivatives as PDE5 inhibitors
    Patent number: 6984641
    Abstract: Selective inhibitors of cGMP-specific PDE, and use of the compounds and salts and solvates thereof as therapeutic agents, are disclosed.
    Type: Grant
    Filed: May 2, 2002
    Date of Patent: January 10, 2006
    Assignee: Lilly Icos LLC.
    Inventors: Mark W. Orme, Jason S. Sawyer, Alain C. Daugan, Agnes Bombrun, Françoise Gellibert, Lisa M. Schultze, Raymond F. Brown, Romain L. Gosmini
  • Hexahydropyrazino[1'2';1,6]pyrido[3,4-b]indole-1,4-diones for the treatment of cardiovascular disorders and erectile dysfunction
    Patent number: 6962918
    Abstract: Compounds of the general structural formula (I), and use of the compounds and salts and solvates thereof, as therapeutic agents.
    Type: Grant
    Filed: September 17, 2001
    Date of Patent: November 8, 2005
    Assignee: Lilly Icos LLC.
    Inventors: Mark W. Orme, Lisa M. Schultze, Jason Scott Sawyer, Alain Claude-Marie Daugan, Raymond Brown
  • Condensed pyrazindione derivatives as PDE inhibitors
    Patent number: 6960587
    Abstract: Compounds of the general structural formula (I), and use of the compounds and salts and solvates thereof, as therapeutic agents.
    Type: Grant
    Filed: October 9, 2001
    Date of Patent: November 1, 2005
    Assignee: Lilly Icos LLC
    Inventors: Mark W. Orme, Lisa M. Schultze, Jason Scott Sawyer
  • Pyrazino[1?,2?:1,6]pyrido[3,4b]indole derivatives
    Patent number: 6911542
    Abstract: Compounds of the general structural formula (I) and use of the compounds and salts and solvates thereof, as therapeutic agents.
    Type: Grant
    Filed: May 15, 2001
    Date of Patent: June 28, 2005
    Assignee: Lilly Icos LLC.
    Inventors: Mark W. Orme, Jason Scott Sawyer, Lisa M. Schultze, Alain Claude-Marie Daugan, Francoise Gellibert
  • Condensed pyrazindione derivatives
    Patent number: 6903099
    Abstract: Compounds of the general structural formula (I) and use of the compounds and salts and solvates thereof, as therapeutic agents.
    Type: Grant
    Filed: May 15, 2001
    Date of Patent: June 7, 2005
    Assignee: Lilly Icos LLC
    Inventors: Mark W. Orme, Jason Scott Sawyer, Lisa M. Schultze
  • Indole derivatives as PDE5-inhibitors
    Patent number: 6878711
    Abstract: Compounds of the general structural formula and use of the compounds and salts and solvates thereof, as therapeutic agents.
    Type: Grant
    Filed: October 9, 2001
    Date of Patent: April 12, 2005
    Assignee: Lilly Icos LLC
    Inventors: Mark W. Orme, Jason Scott Sawyer, Lisa M. Schultze
  • Condensed pyridoindole derivatives
    Patent number: 6858620
    Abstract: Compounds of general structural formula (I), and use of the compounds or salts or solvates thereof as therapeutic agents, are disclosed
    Type: Grant
    Filed: September 17, 2001
    Date of Patent: February 22, 2005
    Assignee: Lilly ICOS, LLC
    Inventors: Mark W. Orme, Jason Scott Sawyer, Alain Claude-Marie Daugan, Romain Luc Marie Gosmini, Lisa M. Schultze
  • Carboline derivatives as pdev inhibitors
    Publication number: 20040171830
    Abstract: Selective inhibitors of cGMP-specific PDE, and use of the compounds and salts and solvates thereof as therapeutic agents, are disclosed.
    Type: Application
    Filed: November 25, 2003
    Publication date: September 2, 2004
    Inventors: Mark W Orme, Jason S Sawyer, Alain C Daugan, Agnes Bombrun, Francois Gellibert, Lisa M Schultze, Raymond E Brown, Romain L Gosmini
  • Tetracyclic compounds as pde5-inhibitors
    Publication number: 20040162291
    Abstract: Compounds of structural formula (I) and use of the compounds and salts and solvates thereof, as therapeutic agents.
    Type: Application
    Filed: November 25, 2003
    Publication date: August 19, 2004
    Inventors: Mark W. Orme, Jason S. Sawyer, Lisa M. Schultze
  • Pyrazino 1',2':1,6 pyrido 3,4-b indole1,4-dione derivatives
    Publication number: 20040152705
    Abstract: Compounds of the general structural formula (I), and use of the compounds and salts and solvates thereof, as thereapeutic agents. In particular, the invention relates to compounds that are potent and selective inhibitors of cyclic guanosine 3′, 5′-monophosphate specific phosphodiesterase (cGMP-specific PDE), in particular PDE5, and have utility in a variety of therapeutic areas wherein such inhibition is considered beneficial, including the treatment of cardiovascular disorders and erectile dysfunction.
    Type: Application
    Filed: November 24, 2003
    Publication date: August 5, 2004
    Inventors: Mark W. Orme, Jason S. Sawyer, Lisa M. Schultze
  • Chemical compounds
    Publication number: 20040082787
    Abstract: Compounds of general structural formula (I), and use of the compounds or salts or solvates thereof as therapeutic agents, are disclosed.
    Type: Application
    Filed: March 3, 2003
    Publication date: April 29, 2004
    Inventors: Mark W Orme, Jason Scott Sawyer, Alain Claude-Marie Daugan, Romain Luc Marie Gosmini, Lisa M Schultze
  • Chemical compounds
    Publication number: 20040038978
    Abstract: Compounds of the general structural formula (I), and use of the compounds and salts and solvates thereof, as therapeutic agents.
    Type: Application
    Filed: April 9, 2003
    Publication date: February 26, 2004
    Inventors: Mark W. Orme, Lisa M. Schultze, Jason Scott Sawyer
  • Chemical compounds
    Publication number: 20030236263
    Abstract: Compounds of the general structural formula (I), and use of the compounds and salts and solvates thereof, as therapeutic agents.
    Type: Application
    Filed: February 27, 2003
    Publication date: December 25, 2003
    Inventors: Mark W. Orme, Lisa M. Schultze, Jason Scott Sawyer, Alain Claude-Marie Daugan, Raymond Brown
  • Indole derivatives as pde5-inhibitors
    Publication number: 20030229080
    Abstract: Compounds of the general structural formula and use of the compounds and salts and solvates thereof, as therapeutic agents.
    Type: Application
    Filed: April 9, 2003
    Publication date: December 11, 2003
    Inventors: Mark W Orme, Jason Scott Sawyer, Lisa M Schultze
  • Chemical compounds
    Publication number: 20030225094
    Abstract: Compounds of the general structural formula (I) and use of the compounds and salts and solvates thereof, as therapeutic agents.
    Type: Application
    Filed: December 6, 2002
    Publication date: December 4, 2003
    Inventors: Mark W Orme, Jason scott Sawyer, LIsa M Schultze, Alain Claude-Marie Daugan, Francoise Gellibert
  • Fused heterocyclic derivatives as phosphodiesterase inhibitors
    Publication number: 20030207867
    Abstract: Compounds of general structural formula (I) and use of the compounds and salts and solvates thereof, as therapeutic agents.
    Type: Application
    Filed: January 15, 2003
    Publication date: November 6, 2003
    Inventors: Mark W. Orme, Jason Scott Sawyer, Lisa M Schultze
  • Nucleotide analog compositions
    Patent number: 6451340
    Abstract: The invention provides crystalline forms of adefovir dipivoxil and methods to prepare the crystals. The compositions and methods of the present invention have desirable properties for large scale synthesis of crystalline adefovir dipivoxil or for its formulation into therapeutic dosages. Invention compositions include an anhydrous crystal form of adefovir dipivoxil.
    Type: Grant
    Filed: September 10, 2001
    Date of Patent: September 17, 2002
    Assignee: Gilead Sciences, Inc.
    Inventors: Murty N. Arimilli, Daphne E. Kelly, Thomas T. K. Lee, Lawrence V. Manes, John D. Munger, Jr., Ernest J. Prisbe, Lisa M. Schultze