Patents by Inventor Lisa M. Schultze

Lisa M. Schultze has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleotide analog compositions
    Publication number: 20020045599
    Abstract: The invention provides crystalline forms of adefovir dipivoxil and methods to prepare the crystals. The compositions and methods of the present invention have desirable properties for large scale synthesis of crystalline adefovir dipivoxil or for its formulation into therapeutic dosages. Invention compositions include an anhydrous crystal form of adefovir dipivoxil.
    Type: Application
    Filed: September 10, 2001
    Publication date: April 18, 2002
    Applicant: Gilead Sciences, Inc.
    Inventors: Murty N. Arimilli, Daphne E. Kelly, Thomas T.K. Lee, Lawrence V. Manes, John D. Munger, Ernest J. Prisbe, Lisa M. Schultze
  • Nucleotide analog composition and synthesis method
    Patent number: 5935946
    Abstract: The invention provides a composition comprising bis(POC)PMPA and fumaric acid (1:1). The composition is useful as an intermediate for the preparation of antiviral compounds, or is useful for administration to patients for antiviral therapy or prophylaxis. The composition is particularly useful when administered orally. The invention also provides methods to make PMPA and intermediates in PMPA synthesis. Embodiments include lithium t-butoxide, 9-(2-hydroxypropyl) adenine and diethyl p-toluenesulfonylmethoxyphosphonate in an organic solvent such as DMF. The reaction results in diethyl PMPA preparations containing an improved by-product profile compared to diethyl PMPA made by prior methods.
    Type: Grant
    Filed: July 25, 1997
    Date of Patent: August 10, 1999
    Assignee: Gilead Sciences, Inc.
    Inventors: John D. Munger, Jr., John C. Rohloff, Lisa M. Schultze
  • Hydrocarbylphenyl diaminodithiol radionuclide complexes and their use in imaging
    Patent number: 5080884
    Abstract: An agent for imaging organs using a radioactive complex of a radioactive metal with a benzene ring having two 2-mercapto-2-methylpropylamino substituents where one of these mercapto substituents is substituted with a hydrocarbyl group.
    Type: Grant
    Filed: February 22, 1991
    Date of Patent: January 14, 1992
    Assignee: Medi-Physics, Inc.
    Inventors: William J. McBride, Ronald M. Baldwin, Janice M. Kerr, Lisa M. Schultze, Nilda Salazar, James M. Chinitz
  • Hydrocarbylphenyl diaminodithiol derivatives
    Patent number: 5026913
    Abstract: An agent for imaging organs using a radioactive complex of a radioactive metal with a benzene ring having two 2-mercapto-2-methylpropylamino substitutents where one of these mercapto substituents is substituted with a hydrocarbyl group.
    Type: Grant
    Filed: August 30, 1990
    Date of Patent: June 25, 1991
    Assignee: Medi-Physics, Inc.
    Inventors: William J. McBride, Ronald M. Baldwin, Janice M. Kerr, Lisa M. Schultze, Nilda Salazar