Abstract: A contact lens comprising one or more microchannels for transport of liquid through the lens is provided. The contact lens can be made by contacting a curable composition with a microfiber that is insoluble in the curable composition; curing the curable composition to provide a polymeric lens body with the microfiber embedded therein; and contacting the polymeric lens body with a solvent to dissolve the microfiber.

Abstract: Technologies for supporting customizations of a database schema are disclosed. In an embodiment, an application programming interface includes an aliasing component and a mapping component, which cooperate to constrain modifications to front-end software to the aliasing component and to constrain modifications to back-end database schema to the mapping component.

Abstract: Technologies for supporting customizations of a database schema are disclosed. In an embodiment, an application programming interface includes an aliasing component and a mapping component, which cooperate to constrain modifications to front-end software to the aliasing component and to constrain modifications to back-end database schema to the mapping component.

Abstract: A method for evaluating a planned well trajectory for avoidance of collision with an existing wellbore includes constructing a bounding box about the planned well trajectory and a bounding box for a trajectory of at least one existing wellbore. If there is no intersection between the bounding boxes, the planned well trajectory is used for drilling a well.

Abstract: The present invention discloses a method and system for collaborative scheduling of production and transportation in supply chains based on improved particle swarm optimization. The method includes the following steps: 1. setting algorithm parameters; 2. randomly generating an initial population; 3. correcting codes; 4. calculating fitness values and updating the speed and the position of particles; 5. performing tournament selection; 6. performing crossover mutation; 7. updating the population; and 8. determining whether a termination condition is satisfied; if so, outputting a globally optimal solution; if not, returning to the step 3. In the present invention, an approximately optimal solution can be obtained in view of the collaborative scheduling problem of production and transportation considering distributed storage, so that the cost is reduced for supply chains and the service level of supply chains is enhanced.

Abstract: A method and system for batch scheduling uniform parallel machines with different capacities based on an improved genetic algorithm are provided. The method is to solve the batch scheduling problem of uniform parallel machines with different capacities. Jobs are distributed to machines by an improved genetic algorithm, and a corresponding batching strategy and a batch scheduling strategy are proposed according to the natural of the problem to obtain a fitness value of a corresponding individual; then, the quality of the solution is improved by a local search strategy; and, a crossover operation is performed on a population based on the fitness of the solution, and the population is continuously updated by repetitive iteration to eventually obtain an optimal solution.

Abstract: Provided is use of a pyrimidine compound or a pharmaceutically acceptable salt thereof in preparation of an anti-cervical cancer medicament. Research of the present invention has found that the above-mentioned pyrimidine compound can be effective against cervical cancer, and has a good inhibition effect on E6 and E7 of HPV16, and indicates that the above-mentioned pyrimidine compound also has a good anti-human papilloma virus effect, providing a new choice for clinical medication.

Abstract: A plug connector includes a case and a securing portion located in the case. The case is configured to receive a coupling end of a socket connector and includes two opposite sidewalls. The securing portion has a plurality of resilient pins configured to electronically couple to the socket connector. An inner surface of each sidewall is configured to abut against a side surface of the coupling end. Each sidewall defines a positioning slot extending outwardly from the inner surface of the sidewall. The positioning slot is configured to engage a positioning block extending from the coupling end. A socket connector matched to the plug connector and a connector assembly including the plug connector and the socket connector are further provided.

Abstract: The present invention provides a conjugate and preparation method thereof, a pharmaceutical composition comprising the conjugate and use of the pharmaceutical composition in the manufacture of a medicament for the treatment or prevention of a disease.

Abstract: Provided is use of a pyrimidine compound or a pharmaceutically acceptable salt thereof in preparation of an anti-cervical cancer medicament. Research of the present invention has found that the above-mentioned pyrimidine compound can be effective against cervical cancer, and has a good inhibition effect on E6 and E7 of HPV16, and indicates that the above-mentioned pyrimidine compound also has a good anti-human papilloma virus effect, providing a new choice for clinical medication.

Abstract: A plug connector includes a case and a securing portion located in the case. The case is configured to receive a coupling end of a socket connector and includes two opposite sidewalls. The securing portion has a plurality of resilient pins configured to electronically couple to the socket connector. An inner surface of each sidewall is configured to abut against a side surface of the coupling end. Each sidewall defines a positioning slot extending outwardly from the inner surface of the sidewall. The positioning slot is configured to engage a positioning block extending from the coupling end. A socket connector matched to the plug connector and a connector assembly including the plug connector and the socket connector are further provided.

Abstract: A method for evaluating a planned well trajectory for avoidance of collision with an existing wellbore includes constructing a bounding box about the planned well trajectory and a bounding box for a trajectory of at least one existing wellbore. If there is no intersection between the bounding boxes, the planned well trajectory is used for drilling a well.

Abstract: Provided is a Lactobacillus salivarius belonging to Lactobacillus salivarius subsp. Salivarius and deposited in China General Microbiological Culture Collection Center with an accession number CGMCC No: 3606. Further provided is a method for preparing a metabolite of the Lactobacillus salivarius, wherein the Lactobacillus salivarius is as described above. Further provided is a composition, comprising viable strains of the Lactobacillus salivarius and/or the metabolite of the Lactobacillus salivarius prepared as described above. Further provided is a use of the composition in preparation of drugs for prevention and/or treatment of cancers and a method for treating and/or preventing cancers. The viable strains of Lactobacillus salivarius and the metabolite of Lactobacillus salivarius provided in the present invention can both remove the genotoxicity of 4-NQQ in vivo, thus exerting an effect of effectively preventing and/or treating cancers.

Abstract: An electronic device containing a polythiophene wherein R represents a side chain, m represents the number of R substituents; A is a divalent linkage; x, y and z represent, respectively, the number of Rm substituted thienylenes, unsubstituted thienylenes, and divalent linkages A, respectively, in the monomer segment subject to z being 0 or 1, and n represents the number of repeating monomer segments in the polymer or the degree of polymerization.

Abstract: An electronic device containing a polythiophene wherein R represents a side chain, m represents the number of R substituents; A is a divalent linkage; x, y and z represent, respectively, the number of Rm substituted thienylenes, unsubstituted thienylenes, and divalent linkages A, respectively, in the monomer segment subject to z being 0 or 1, and n represents the number of repeating monomer segments in the polymer or the degree of polymerization.

Abstract: A method for forwarding packets is disclosed herein. After packets are received, the packets are forwarded to the corresponding transmission channels according to the packet type, or according to the packet type and the message type and/or service type. A system and an apparatus for forwarding packets are disclosed herein to forward important packets and packets with higher priorities more rapidly and more reliably at higher QoS, especially when the resources are not enough or the network is congested.

Abstract: An electronic device containing a polythiophene wherein R represents a side chain, m represents the number of R substituents; A is a divalent linkage; x, y and z represent, respectively, the number of Rm substituted thienylenes, unsubstituted thienylenes, and divalent linkages A, respectively, in the monomer segment subject to z being 0 or 1, and n represents the number of repeating monomer segments in the polymer or the degree of polymerization.

Abstract: An electronic device containing a polythiophene wherein R represents a side chain, m represents the number of R substituents; A is a divalent linkage; x, y and z represent, respectively, the number of Rm substituted thienylenes, unsubstituted thienylenes, and divalent linkages A, respectively, in the monomer segment subject to z being 0 or 1, and n represents the number of repeating monomer segments in the polymer or the degree of polymerization.

Abstract: The present invention relates to a peptide derivative represented by the general formula (I) or a salt thereof: Z-(CH2)n—CO—NH-Leu-Ile-Gly-AA1-AA2-CO—R (I) wherein Z represents an aryl group which may or may not have a substituent or a heteroaryl group which may or may not have a substituent; n represents 0, 1 or 2: AA1-AA2 represents Lys-Val or Arg-Leu; and R represents —OH or —NH2, and relates to a pharmaceutical composition comprising a peptide derivative represented by the general formula (I) or a salt thereof, and a pharmaceutically acceptable carrier thereof. The peptide derivative is useful as a prophylactic and therapeutic agent of dysfunction of masticatory, dysphagia, dysgeusia, ozostomia, intra-oral cavity dysphoria, intra-oral cavity infections, intra-oral cavity inflammations, dry eye, ectocornea detachment, keratitis, corneal ulcer, conjunctivitis, stomach ulcer, duodenal ulcer, gastritis, diarrhea, enteritis or Sjogren's syndrome.

Abstract: Polythiophenes of the formula wherein R is a side chain; m is the number of substituents; A is a divalent linkage; x, y and z represent, respectively, the numbers of R substituted thienylene, unsubstituted thienylene, and divalent linkages A in the monomer segment with z being either 0 or 1; and n represents the number of the repeating monomer segments in the polymer chain or the degree of polymerization.