Patents by Inventor Maksym A. Vodyanyk

Maksym A. Vodyanyk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Generation of mature myelomonocytic cells through expansion and differentiation of pluripotent stem cell-derived lin-CD34+CD43+CD45+progenitors
    Publication number: 20100081199
    Abstract: A method for efficient generation of neutrophils, eosinophils, macrophages, osteoclasts, dendritic cells an Langerhans cells from human embryonic stem cells is disclosed.
    Type: Application
    Filed: September 24, 2009
    Publication date: April 1, 2010
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Igor I. Slukvin, Kyung-Dal Choi, Maksym A. Vodyanyk
  • Generation of Clonal Mesenchymal Progenitors and Mesenchymal Stem Cell Lines Under Serum-Free Conditions
    Publication number: 20100015705
    Abstract: Methods for obtaining multipotent mesenchymal stem cells under serum-free conditions and methods for identifying multipotent mesenchymal progenitor cells are disclosed.
    Type: Application
    Filed: September 4, 2009
    Publication date: January 21, 2010
    Inventors: Maksym A. Vodyanyk, Junying Yu, James A. Thomson
  • Generation of clonal mesenchymal progenitors and mesenchymal stem cell lines under serum-free conditions
    Patent number: 7615374
    Abstract: Methods for obtaining multipotent mesenchymal stem cells under serum-free conditions and methods for identifying multipotent mesenchymal progenitor cells are disclosed.
    Type: Grant
    Filed: February 1, 2008
    Date of Patent: November 10, 2009
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Maksym A. Vodyanyk, Junying Yu, James A. Thomson, Igor I. Slukvin
  • GENERATION OF CLONAL MESENCHYMAL PROGENITORS AND MESENCHYMAL STEM CELL LINES UNDER SERUM-FREE CONDITIONS
    Publication number: 20090081784
    Abstract: Methods for obtaining multipotent mesenchymal stem cells under serum-free conditions and methods for identifying multipotent mesenchymal progenitor cells are disclosed.
    Type: Application
    Filed: February 1, 2008
    Publication date: March 26, 2009
    Inventors: Maksym A. Vodyanyk, Junying Yu, James A. Thomson, Igor I. Slukvin
  • ERYTHROID CELLS PRODUCING ADULT-TYPE Beta-HEMOGLOBIN GENERATED FROM HUMAN EMBRYONIC STEM CELLS
    Publication number: 20080003674
    Abstract: Methods and compositions of erythroid cells that produce adult ?-hemoglobin, generated by culturing CD31+, CD31+/CD34+ or CD34+ cells from embryonic stem cells under serum-free culture conditions.
    Type: Application
    Filed: February 8, 2007
    Publication date: January 3, 2008
    Inventors: Igor Slukvin, James Thomson, Maksym Vodyanyk, Maryna Gumenyuk
  • Multipotent lymphohematopoietic progenitor cells
    Publication number: 20070072295
    Abstract: This invention relates to hematopoietic precursors derived from human embryonic stem cells. In the culture of differentiated cells from human ES cells, the fully committed hematopoietic precursors are CD34+ and CD43+ but not CD45+. If the cells are cultured until they express CD45, then the cells lose the ability to produce differentiated cells of the lymphoid lineages.
    Type: Application
    Filed: September 14, 2006
    Publication date: March 29, 2007
    Inventors: Igor Slukvin, Maksym Vodyanyk, James Thomson
  • Method of forming dendritic cells from embryonic stem cells
    Publication number: 20060275901
    Abstract: This invention relates to the culture of dendritic cells from human embryonic stem (ES) cells. Human ES cells are first cultured into hematopoietic cells by co-culture with stromal cells. The cells now differentiated into the hematopoietic lineage are then cultured with GM-CSF to create a culture of myeloid precursor cells. Culture of the myeloid precursor cells with the cytokines GM-CSF and IL-4 causes functional dendritic cells to be generated. The dendritic cells have a unique phenotype, as indicated by their combination of cell surface markers.
    Type: Application
    Filed: May 31, 2006
    Publication date: December 7, 2006
    Inventors: Igor Slukvin, James Thomson, Maksym Vodyanyk, Maryna Gumenyuk