Patents by Inventor Manfred Weigele

Manfred Weigele has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS, COMPOSITIONS AND METHODS OF USE AGAINST STRESS GRANULES
    Publication number: 20180305334
    Abstract: Herein, compounds, compositions and methods for modulating inclusion formation and stress granules in cells related to the onset of neurodegenerative diseases, musculoskeletal diseases, cancer, ophthalmological diseases, and viral infections are described.
    Type: Application
    Filed: October 14, 2016
    Publication date: October 25, 2018
    Inventors: Glenn R. Larsen, Manfred Weigele, Joseph P. Vacca, Duane A. Burnett, Amy Ripka
  • METHODS AND COMPOSITIONS FOR TREATING DISORDERS
    Publication number: 20180133170
    Abstract: Compounds and compositions for treating disorders related to TRPA1 are described herein.
    Type: Application
    Filed: June 30, 2017
    Publication date: May 17, 2018
    Inventors: Manfred Weigele, Jayhong A. Chong, Glenn R. Larsen, Neil J. Hayward, Amy Ripka, Howard Ng, Magdalene M. Moran, Christopher Fanger, Donato Del Camino, Steven P. Adams
  • COMPOUNDS, COMPOSITIONS AND METHODS OF USE
    Publication number: 20170369474
    Abstract: Herein, compounds, compositions and methods for modulating inclusion formation and stress granules in cells related to the onset of neurodegenerative diseases, musculoskeletal diseases, cancer, ophthalmological diseases, and viral infections are described.
    Type: Application
    Filed: December 4, 2015
    Publication date: December 28, 2017
    Inventors: Glenn R. Larsen, Manfred Weigele, Joseph P. Vacca
  • COMPOUNDS, COMPOSITIONS AND METHODS OF USE
    Publication number: 20170360726
    Abstract: Herein, compounds, compositions and methods for modulating inclusion formation and stress granules in cells related to the onset of neurodegenerative diseases, musculoskeletal diseases, cancer, ophthalmological diseases, and viral infections are described.
    Type: Application
    Filed: December 4, 2015
    Publication date: December 21, 2017
    Inventors: Glenn R. Larsen, Manfred Weigele, Joseph P. Vacca
  • COMPOUNDS FOR MODULATING TRPV3 FUNCTION
    Publication number: 20170224687
    Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
    Type: Application
    Filed: September 16, 2016
    Publication date: August 10, 2017
    Inventors: Jayhong A. Chong, Christopher Fanger, Glenn R. Larsen, Magdalene M. Moran, Howard Ng, Amy Ripka, Dennis John Underwood, Manfred Weigele, Xiaoguang Zhen
  • COMPOUNDS FOR MODULATING TRPV3 FUNCTION
    Publication number: 20170020858
    Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
    Type: Application
    Filed: February 24, 2016
    Publication date: January 26, 2017
    Inventors: Jayhong A. Chong, Christopher Fanger, Glenn R. Larsen, William C. Lumma, JR., Magdalene M. Moran, Amy Ripka, Dennis John Underwood, Manfred Weigele, Xiaoguang Zhen
  • Compounds for modulating TRPV3 function
    Patent number: 9486455
    Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
    Type: Grant
    Filed: March 4, 2011
    Date of Patent: November 8, 2016
    Assignee: HYDRA BIOSCIENCES, INC.
    Inventors: Jayhong A. Chong, Christopher Fanger, Glenn R. Larsen, Magdalene M. Moran, Howard Ng, Amy Ripka, Dennis John Underwood, Manfred Weigele, Xiaoguang Zhen
  • COMPOUNDS FOR MODULATING TRPV3 FUNCTION
    Publication number: 20160256447
    Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
    Type: Application
    Filed: October 7, 2015
    Publication date: September 8, 2016
    Inventors: Magdalene M. Moran, Jayhong A. Chong, Christopher Fanger, Amy Ripka, Glenn R. Larsen, Xiaoguang Zhen, Dennis John Underwood, Manfred Weigele
  • Compounds of modulating TRPV3 function
    Patent number: 9181219
    Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
    Type: Grant
    Filed: January 29, 2013
    Date of Patent: November 10, 2015
    Assignee: HYDRA BIOSCIENCES, INC.
    Inventors: Magdalene M. Moran, Jayhong A. Chong, Christopher Fanger, Amy S. Ripka, Glenn R. Larsen, Xiaoguang Zhen, Dennis John Underwood, Manfred Weigele
  • COMPOUNDS FOR MODULATING TRPV3 FUNCTION
    Publication number: 20150299225
    Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
    Type: Application
    Filed: November 14, 2014
    Publication date: October 22, 2015
    Applicant: HYDRA BIOSCIENCES, INC.
    Inventors: Jayhong A. Chong, Christopher Fanger, Glenn R. Larsen, William C. Lumma, JR., Magdalene M. Moran, Amy Ripka, Dennis John Underwood, Manfred Weigele, Xiaoguang Zhen, Anu Mahadevan, Peter Meltzer
  • Compounds, compositions, and methods for the treatment of ?-amyloid diseases and synucleinopathies
    Patent number: 8916598
    Abstract: Dihydroxyaryl compounds and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of synucleinopathies, such as observed in Parkinson's disease, and the manufacture of medicaments for such treatment.
    Type: Grant
    Filed: August 11, 2011
    Date of Patent: December 23, 2014
    Assignee: Proteotech Inc
    Inventors: Luke A. Esposito, F. Michael Hudson, Thomas Lake, Joel Cummings, Manfred Weigele, Alan D. Snow
  • Compounds for modulating TRPV3 function
    Patent number: 8916550
    Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
    Type: Grant
    Filed: November 15, 2006
    Date of Patent: December 23, 2014
    Assignee: Hydra Biosciences, Inc.
    Inventors: Jayhong A. Chong, Christopher Fanger, Glenn R. Larsen, William C. Lumma, Jr., Magdalene M. Moran, Amy Ripka, Dennis John Underwood, Manfred Weigele, Xiaoguang Zhen, Anu Mahadevan, Peter Meltzer
  • Compounds, compositions and methods for the treatment of beta-amyloid diseases and synucleinopathies
    Patent number: 8829198
    Abstract: Dihydroxyaryl compounds and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of ?-amyloid diseases, such as observed in Alzheimer's disease, and synucleinopathies, such as observed in Parkinson's disease, and the manufacture of medicaments for such treatment.
    Type: Grant
    Filed: October 3, 2008
    Date of Patent: September 9, 2014
    Assignee: Proteotech Inc
    Inventors: Luke A. Esposito, F. Michael Hudson, Thomas Lake, Joel Cummings, Manfred Weigele, Alan D. Snow, Lesley Larsen
  • COMPOUNDS FOR MODULATING TRPV3 FUNCTION
    Publication number: 20140155417
    Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
    Type: Application
    Filed: August 30, 2013
    Publication date: June 5, 2014
    Applicant: HYDRA BIOSCIENCES, INC.
    Inventors: Jayhong A. Chong, Christopher Fanger, Glenn R. Larsen, William C. Lumma, JR., Anu Mahadevan, Peter Meltzer, Magdalene M. Moran, Amy Ripka, Dennis Underwood, Manfred Weigele, Xiaoguang Zhen
  • Compounds of Modulating TRPV3 Function
    Publication number: 20140011840
    Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
    Type: Application
    Filed: January 29, 2013
    Publication date: January 9, 2014
    Applicant: Hydra Biosciences, Inc.
    Inventors: Magadalene M. Moran, Jayhong A. Chong, Christopher Fanger, Amy S. Ripka, Glenn R. Larsen, Xiaoguang Zhen, Dennis John Underwood, Manfred Weigele
  • Compounds, compositions, and methods for the treatment of ?-amyloid diseases and synucleinopathies
    Patent number: 8592476
    Abstract: Dihydroxyaryl compounds and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of ?-amyloid diseases, such as observed in Alzheimer's disease, and synucleinopathies, such as observed in Parkinson's disease, and the manufacture of medicaments for such treatment.
    Type: Grant
    Filed: April 26, 2012
    Date of Patent: November 26, 2013
    Assignee: ProteoTech, Inc.
    Inventors: Luke A. Esposito, F. Michael Hudson, Thomas Lake, Joel Cummings, Manfred Weigele, Alan Snow, Lesley Larsen
  • Substituted pyrimido 4.5-d pyrimidin-4-one compounds for modulating TRPV3 function
    Patent number: 8552009
    Abstract: The present application relates to compounds of Formula I as defined herein, and methods for treating pain and other conditions related to TRPV3.
    Type: Grant
    Filed: February 7, 2011
    Date of Patent: October 8, 2013
    Inventors: Jayhong A. Chong, Christopher Fanger, Glenn R. Larsen, William C. Lumma, Jr., Magdalene M. Moran, Amy S. Ripka, Dennis John Underwood, Manfred Weigele, Xiaoguang Zhen, Anu Mahadevan, Peter Meltzer
  • METHODS AND COMPOSITIONS FOR TREATING DISORDERS
    Publication number: 20130059869
    Abstract: Compounds and compositions for treating disorders related to TRPA1 are described herein.
    Type: Application
    Filed: February 22, 2012
    Publication date: March 7, 2013
    Inventors: Howard Ng, Manfred Weigele, Magdalene Moran, Jayhong Chong, Christopher Fanger, Glenn R. Larsen, Donato Del Camino, Neil Hayward, Steven P. Adams, Amy Ripka
  • Compounds for modulating TRPV3 function
    Patent number: 8389546
    Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
    Type: Grant
    Filed: July 1, 2011
    Date of Patent: March 5, 2013
    Assignee: Hydra Biosciences, Inc.
    Inventors: Magdalene M. Moran, Jayhong A. Chong, Christopher Fanger, Amy Ripka, Glenn R. Larsen, Xiaoguang Zhen, Dennis John Underwood, Manfred Weigele
  • COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF BETA-AMYLOID DISEASES AND SYNUCLEINOPATHIES
    Publication number: 20120252858
    Abstract: Dihydroxyaryl compounds and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of ?-amyloid diseases, such as observed in Alzheimer's disease, and synucleinopathies, such as observed in Parkinson's disease, and the manufacture of medicaments for such treatment.
    Type: Application
    Filed: April 26, 2012
    Publication date: October 4, 2012
    Inventors: Luke A. Esposito, F. Michael Hudson, Thomas Lake, Joel Cummings, Manfred Weigele, Alan D. Snow, Lesley Larsen