Abstract: A surface cleaner and a method for using the surface cleaner are disclosed. The surface cleaner comprises a cleaner body with a lid, a hand gripping post and a thumb rest, The cleaning may be performed by a pad attached to the bottom of the cleaner body. Alternatively a sheet, such as a cloth or a paper towel, folded into the inside of the surface cleaner may be used. To hold the surface cleaner, the hand gripping post is inserted between the middle and ring fingers and the thumb is rested on the thumb rest.

Abstract: A method by which an orthodontic appliance is automatically designed and manufactured from digital lower jaw and tooth shape data of a patient provides for the scanning of the mouth of a patient to produce a three-dimensional digitized model of the shapes of the patient's teeth and their positions in the patient's mouth. The appliance is automatically designed according to the final design, which also can be interactively modified and approved by the orthodontist, with the computer recalculating the effects on the treatment as a result of the doctor's changes. Brackets are fabricated as an integrated set, either by cutting slots therein or by building the brackets in layers. Three-dimensional custom jigs are automatically made to exactly position the brackets on a patient's teeth.

Abstract: Embodiments provide systems and methods for maintaining immutable data in an archiving system using random access memory. To ensure data is immutable, novel pointers are maintained in the hardware/firmware of the drive ports and on the removable disk drives. For example, a hardware/firmware in a modular drive bay maintains a pointer to a memory address in the removable disk drive memory that cannot write to a memory block that precedes the pointer. Data may only be stored after the pointer in the removable disk drive. As such, once data is written to the removable disk drive, the data cannot be overwritten although the removable disk drive employs random access memory.

Abstract: Tissue expanders and their methods of use.

Abstract: Tissue expanders and their methods of use.

Abstract: Embodiments provide unique and novel systems and methods for deleting data on removable disk drives. In embodiments, the removable disk drives store data that may be erased such that the data is considered destroyed but that allows the removable disk drive to be reused. The archiving system can determine which data should be erased. Then, the data is digitally shredded on sector boundaries of the removable disk drives such that the reclaimed memory cannot be read to decipher the erased data. In alternative embodiments, data is written across sector boundaries such that two or more files may occupy a single sector. A journal area, in embodiments, allows for copying the data in a sector with two or more files, digitally shredding the sectors in the removable disk drive, and rewriting the data that was not to be digitally shredded to the original location of the data.

Abstract: A thermally conductive polymeric drinking surface for a beverage container is provided. The thermally conductive polymeric drinking surface may be an insert for a bottle or other covering configured to be formed around the mouth of a drinking container, such as a cup. The high thermal conductivity of the drinking surface contributes to the transfer of the temperature of the contents of the container to the mouth or lips of the consumer by reducing the time and energy consumption of the chilling processes being applied via the beverage or an external cooling mechanism.

Abstract: A conjugate comprises: (a) a mitochondrial membrane-permeant peptide; (b) an active agent or compound of interest such as a detectable group or mitochondrial protein or peptide; and (c) a mitochondrial targeting sequence linking said mitochondrial membrane-permeant peptide and said active mitochondrial protein or peptide. The targeting sequence is one which is cleaved within the mitochondrial matrix, and not cleaved within the cellular cytoplasm, of a target cell into which said compound is delivered. Methods of use of such compounds are also described.

Abstract: Embodiments provide unique and novel systems and methods for deleting data on removable disk drives. In embodiments, the removable disk drives store data that may be erased such that the data is considered destroyed but that allows the removable disk drive to be reused. The archiving system can determine which data should be erased. Then, the data is digitally shredded on sector boundaries of the removable disk drives such that the reclaimed memory cannot be read to decipher the erased data. In alternative embodiments, data is written across sector boundaries such that two or more files may occupy a single sector. A journal area, in embodiments, allows for copying the data in a sector with two or more files, digitally shredding the sectors in the removable disk drive, and rewriting the data that was not to be digitally shredded to the original location of the data.

Abstract: A conjugate comprises: (a) a mitochondrial membrane-permeant peptide; (b) an active agent or compound of interest such as a detectable group or mitochondrial protein or peptide; and (c) a mitochondrial targeting sequence linking said mitochondrial membrane-permeant peptide and said active mitochondrial protein or peptide. The targeting sequence is one which is cleaved within the mitochondrial matrix, and not cleaved within the cellular cytoplasm, of a target cell into which said compound is delivered. Methods of use of such compounds are also described.

Abstract: An acetyl xylan esterase variant having perhydrolytic activity is provided for producing peroxycarboxylic acids from carboxylic acid esters and a source of peroxygen. More specifically, a Thermotoga maritima acetyl xylan esterase gene was modified using error-prone PCR and site-directed mutagenesis to create an enzyme catalyst characterized by an increase in the ratio of peracetic acid formation to peracetic acid hydrolysis specific activities (PAAF/PAAH ratio). The variant acetyl xylan esterase may be used to produce peroxycarboxylic acids suitable for use in a variety of applications such as cleaning, disinfecting, sanitizing, bleaching, wood pulp processing, and paper pulp processing applications.

Abstract: Tissue expanders and their methods of use.

Abstract: Stopper rod having an elongated body of refractory material, a passageway extending longitudinally in the body from an end thereof which is uppermost in use, a carrier rod having a part fixedly received in the passageway and a further part outside of the passageway for attachment to a lifting device for the stopper rod. The passageway has an enlarged part which defines a sealing surface spaced from the end of the body, an insert around the carrier rod having at least a part thereof received in the enlarged part, a retention element on the carrier rod, and an expandable element disposed between the insert and the retention element. The material of the insert has a co-efficient of thermal expansion no greater than that of the carrier rod. Expansion of the expandable element, in use, is greater than that of the carrier rod.

Abstract: A covering apparatus or play tent is designed to sit disposed around a suspended platform swing. The tent is attached to a platform swing. The swing which is suspended by a rope from the ceiling has the ability to move forward, backward, laterally, and to rotate in both directions. Thus, the occupants have the ability to experience all of these movements while remaining inside the tent that is attached to the swing. The tent can be made of light weight canvas and has four isosceles trapezoidal sides with one side acting as a door. The door has a small inset window made of mesh with a material flap for closure. The tent may have both a ceiling and a floor. The outside of the tent has three small panels of felt which are attached to the tent for use with stories and literacy concepts.

Abstract: A medical device and procedure is described for sterilizing a female. A two-part procedure includes an immediate sterilization part and a permanent sterilization part. The immediate sterilization part provides immediate sterility that endures at least until the permanent effects of a tubal occlusion procedure provide permanent sterility.

Abstract: A process is provided for producing peroxycarboxylic acids from carboxylic acid esters. More specifically, carboxylic acid esters are reacted with an inorganic peroxide, such as hydrogen peroxide, in the presence of an enzyme catalyst having perhydrolysis activity. The present perhydrolase catalysts are classified as members of the carbohydrate esterase family 7 (CE-7) based on the conserved structural features. Further, disinfectant formulations comprising the peracids produced by the processes described herein are provided.

Abstract: A process is provided for producing peroxycarboxylic acids from carboxylic acid esters. More specifically, carboxylic acid esters are reacted with an inorganic peroxide, such as hydrogen peroxide, in the presence of an enzyme catalyst having perhydrolysis activity. The present perhydrolase catalysts are classified as members of the carbohydrate esterase family 7 (CE-7) based on the conserved structural features. Further, disinfectant formulations comprising the peracids produced by the processes described herein are provided.

Abstract: A surface cleaner and a method for using the surface cleaner are disclosed. The surface cleaner comprises a cleaner body with a lid, a hand gripping post and a thumb rest. The cleaning may be performed by a pad attached to the bottom of the cleaner body. Alternatively a sheet, such as a cloth or a paper towel, folded into the inside of the surface cleaner may be used. To hold the surface cleaner, the hand gripping post is inserted between the middle and ring fingers and the thumb is rested on the thumb rest.

Abstract: The invention is a beverage container that provides a flavor delivery system capable of delivering a burst of flavor when a drinker places her mouth to portions of the beverage container. The flavor delivery system can provide visual and fragrance cues to indicate the type of flavor to be expected from a flavored beverage resident within the beverage container or from flavor components included within the flavor delivery system.

Abstract: A thermally conductive polymeric drinking surface for a beverage container is provided. The thermally conductive polymeric drinking surface may be an insert for a bottle or other covering configured to be formed around the mouth of a drinking container, such as a cup. The high thermal conductivity of the drinking surface contributes to the transfer of the temperature of the contents of the container to the mouth or lips of the consumer by reducing the time and energy consumption of the chilling processes being applied via the beverage or an external cooling mechanism.