Abstract: Methods and systems for generating a model to be used for evaluating credit and loan applications are provided. The method includes: training a first model by using all features included in a universe of candidate features; measuring a first metric that relates to an accuracy of the first model and a second metric that relates to a disparity of the first model; constructing a graph based on pairwise correlations of the features; clustering the features into feature sets; estimating a respective disparity contribution associated with each feature set; selecting feature sets to be included in a second model; training, the second model; measuring the first metric and the second metric with respect to the second model; and determining whether the second model satisfies a predetermined accuracy level and a predetermined disparity reduction with respect to the first model.

Abstract: Systems and methods for frequency management, including: an online media service configured to: receive a request for a media item, the request including a recipient identifier; identify a set of candidate media items ranked by a set of matching criteria; a frequency management service configured to: perform a query against a lookup service, where the query includes (i) an entity identifier of at least one candidate media item of the set of candidate media items, and (ii) the recipient identifier; receive a response from the lookup service including a quantity of impressions associated with the entity identifier and the recipient identifier; identify a predefined frequency threshold; determine that the frequency threshold is exceeded and exclude the at least one candidate media item from a result set based on the determination; and provide the result set including an identifier of at least one other candidate media item.

Abstract: The invention provides novel inhibitors of hedgehog signaling that are useful as a therapeutic agents for treating malignancies where the compounds have the general formula I: wherein A, X, Y R1, R2, R3, R4, m and n are as described herein.

Abstract: A pancreatin preparation having reduced viral infectivity includes one or more pancreatin enzymes and peracetic acid (PAA). At least one pancreatin enzyme may be derived from an animal source such as a porcine pancreas gland. In a particular embodiment, the one or more pancreatin enzymes are selected from the group consisting of lipases, proteases, and amylases.

Abstract: A food recycler can include a case having a case volume between 8.79 liters and 35 liters, a control system, a user interface in electrical communication with the control system, and a bucket being configured with a bucket volume, wherein a ratio of the bucket volume to the case volume is between 0.0717 and 0.2857. The recycler can include a motor in communication with the control system, the motor being configured adjacent at least in part to the bucket, a gearbox configured below the bucket and in mechanical communication with the motor, a filter system having at least one filter and configured to receive air from a top portion of the bucket and a drying component configured to remove water from waste food items.

Abstract: The invention provides anti-CfaE antibodies and methods of using the same.

Abstract: Systems and methods are described for generating record clusters. The methods comprise receiving a plurality of records from data sources and providing at least a subset of the records to a scoring model that determines scores for various pairings of the records, a score for a given pair of the records representing a probability that the given pair of records contain data elements about the same entity. The method further comprises generating a graph data structure that includes a plurality of nodes, individual nodes representing a different record from the records. The method also comprises assigning a different unique identifier to individual clusters of the final clusters and responding to a request for data regarding a given entity by providing aggregated data elements from those records of the records associated with a cluster of the final clusters having an identifier that represents the given entity.

Abstract: There is disclosed squaraine compounds of formula I: wherein each of Y1 and Y2 is independently chosen from an optionally substituted amino group and an optionally substituted aryl group. Also described are organic optoelectronic devices comprising a Donor-Acceptor heterojunction that is formed from one or more of the squaraine compounds. A method of making the disclosed device, which may include one or more sublimation step for depositing said squaraine compound, is also disclosed.

Abstract: Various embodiments disclosed herein describe photonic passive delay lines that have a waveguide wound into a plurality of straight segments and bends. The photonic passive delay lines are configured to reduce losses from parasitic modes of light generated at the bends. Embodiments of the photonic passive delay lines vary the dimensions of the straight segments to provide different amounts of dephasing between a mode of input light received by the photonic passive delay line and one or more parasitic modes.

Abstract: Offshore systems and methods may be configured for offshore power generation and carbon dioxide injection for enhanced gas recovery for gas reservoirs. For example, a method may include: providing an offshore facility including a gas turbine, and a gas separator; producing a produced gas from a gas reservoir to the offshore facility; combusting the produced gas in a gas turbine to produce power and a flue gas; at least partially removing nitrogen from the flue gas in a gas separator to produce a carbon dioxide-enriched flue gas and a nitrogen-enriched flue gas; compressing the carbon dioxide-enriched flue gas in a gas compressor to produce a compressed gas; and injecting the compressed gas from the gas compressor into the gas reservoir, wherein 80 mol % or more of hydrocarbon in the produced gas is combusted and/or injected into the gas reservoir.

Abstract: A damped compressor used in mobile appliances. The appliances may comprise a compressor which is disposed within a housing and is in fluid communication with a refrigerant system. Within the housing there is an improved damping or stabilizer system which limits movement of electric or mechanical portions, or both, of the compressor within the housing. At startup and shutdown, when oscillations of the components within the housing are generally maximized, the components are limited from contacting the housing internal structure so as to inhibit damage to the compressor and reduce the noise associated with such contact. The components are also damped from movement associated with the mobile application of the compressor.

Abstract: Disclosed herein is a method and a data processing system for environment evaluation, and a computer-readable storage medium with a computer program for executing the aforementioned method stored thereon. A data processing system according to one aspect comprises: at least one processor; at least one memory; and a computer program stored on the memory and executable on the processor, wherein execution of the computer program on the processor results in the following operations: obtaining user evaluations of an environment and environmental parameter measurements from a plurality of mobile devices; and generating evaluation information about the environment from the user evaluations and the environmental parameter measurements.

Abstract: A lateral flow assay device of the present disclosure has numerous features to ensure correct operation of the device under gravity, such as vent pockets for enabling the flow of sample fluid from one chamber to the next when the vent pocket is unsealed. The vent pockets have protrusions to help prevent accidental resealing. The device also can have a gasket to ensure free air movement between open vent pockets. Flow control features that protrude horizontally into a chamber proximal to an outlet act to deflect the flow to the side of the chamber opposite from the outlet, prior to the flow entering the outlet. Such features can reduce the flow velocity of the sample fluid and increase the effective fluid flow path length, enhance mixing of reagents with a sample, and enabling more accurate control of fluid flow in the device.

Abstract: An automated method for performing an assay of the present disclosure can be performed in a microfluidic device that is a lateral flow device having numerous features to ensure correct operation of the device under gravity, such as vent pockets for enabling the flow of sample fluid from one chamber to the next when the vent pocket is unsealed. Each chamber can have a reagent recess proximal to an inlet end of the chamber. A reagent pellet formed in a reagent recess can be effectively mixed with a sample as the sample flows into the chamber. A flexible circuit with patterned metallic electrical components disposed on a heat stable material can be in direct contact with fluid in the chambers and has resistive heating elements aligned with, for example, a chamber for performing an amplification reaction.

Abstract: Friction material that is substantially free of elemental metals, metal alloys, and antimony trisulfide, wherein the solid lubricant includes a metal sulfide. The disclosed compositions of the friction material are believed to be more environment-friendly than conventional compositions. However, the substantial elimination of elemental metals, metal alloys, and antimony trisulfide from the disclosed compositions is performed in a manner that does not appear to substantially impact the friction performance and noise behavior of the corresponding brake components. Moreover, it is believed that at least some of the disclosed compositions increase the useful lifespan of the brake components and reduce wear of the rotors. The longer brake-components lifespan and lower rotor wear provide additional benefits in terms of reducing non-exhaust-related vehicle emissions, which further alleviates the environmental impact of traffic emissions.

Abstract: A chiller includes an evaporator, a compressor including a prime mover, a first pressure sensor that detects a first pressure in the evaporator, a second pressure sensor that detects a second pressure in a condenser, and a controller. The controller determines a predicted energy level of the compressor based on the first pressure and the second pressure, the predicted energy level associated with liquid droplet flow into the compressor, compares the predicted energy level to an operating energy level, and modifies the at least one of the input power and the input current to the prime mover based on the comparison satisfying a modification condition.

Abstract: The present invention provides a heating, ventilation, and air-conditioning (HVAC) system using an A2L refrigerant and a method of installing the HVAC system in a building. The HVAC system includes an indoor unit having a heat exchanger that uses an A2L refrigerant, a blower, an outdoor unit, an A2L control board, and one or more A2L sensors configured to detect an amount of A2L refrigerant. In one or more embodiments, the indoor unit is electrically coupled to the blower, the A2L control board, and the outdoor unit. Also, in one or more embodiments, the A2L control board is also electrically coupled to the blower and the one or more A2L sensors.

Abstract: A multi-assistant speech-processing system that centrally determines multiple execution plans to respond to a user input. A central component determines whether a particular input should be processed using a requested assistant or a different assistant or should be terminated. Assistant handoff may be determined based on system policies as well as user input-specific data. A ranked list of execution options may be supplemented by augmented data corresponding to messages to a user. The system may attempt to execute plans in the ranked order until a plan succeeds.

Abstract: The present disclosure provides isolated promoters, transgene expression cassettes, vectors, kits, and methods for treatment of C9ORF72 associated diseases, including ALS and FTD.

Abstract: Techniques for specifying and implementing a software application targeted for execution on a multiprocessor array (MPA). The MPA may include a plurality of processing elements, supporting memory, and a high bandwidth interconnection network (IN), communicatively coupling the plurality of processing elements and supporting memory. In some embodiments, software code may specify one or more cell definitions that include: program instructions executable to perform a function and one or more language constructs. The software code may further instantiate first, second, and third cell instances, each of which is an instantiation of one of the one or more cell definitions, where the instantiation includes configuration of the one or more language constructs such that: the first and second cell instances communicate via respective communication ports and the first and second cell instances are included in the third cell instance.