Abstract: The present invention is directed to novel compositions and methods utilizing delivery agents comprising protein cages, medical imaging agents and therapeutic agents.

Abstract: A retroreflective laminate sheeting has a viewing surface having a retroreflective layer which has a first cap-Y value of a viewing surface side thereof. A plurality of discrete pigmented indicia are disposed on the viewing surface side of the retroreflective layer. The pigmented indicia define a second cap-Y value of the viewing surface of the sheeting, the second cap-Y value being less than the first cap-Y value. One method of making a retroreflective sheeting includes forming a retroreflective layer on a web, the web moving in a web direction. The method includes applying a pigmented material proximate the retroreflective layer, the pigmented material preferably forming a plurality of parallel stripes oriented substantially in at least one of the web direction and a direction orthogonal to the web direction.

Abstract: An optical interface device is provided for use in an undersea optical transmission system that includes an undersea optical transmission path, a plurality of optical repeaters located along the optical transmission path, and a selected one of any of a plurality of different vendor supplied optical transmission terminals each of which has a vendor-specific interface. The optical interface device includes a signal processing unit providing signal conditioning to optical signals received from the vendor-specific interface of the selected optical transmission terminal so that the optical signals are suitable for transmission through the undersea optical transmission path. A gain monitoring arrangement is also provided for determining a change in gain provided by any one of the optical repeaters.

Abstract: The present invention is directed to novel compositions and methods utilizing delivery agents comprising protein cages, medical imaging agents and therapeutic agents.

Abstract: A memory management system provides microcode instructions that are divided into multiple tuned phases and stored as separate modules inside a phase code depository. A microcode manager, containing a mode detector, sequence identifier, code loader, drawing data processor and phase executor, interacts with a microcode processor and the phase code depository. The mode detector evaluates a user request for a desired mode. In response to a command from the mode detector, the sequence identifier selects a correct phase sequence that is needed to implement the desired mode. The code loader transfers the phase sequence from the phase code depository to the microcode processor where it is stored in a microcode instruction memory. The memory address for each module within the phase sequence is written to a microcode data memory.

Abstract: In an optical communication system that includes a transmitting terminal, a receiving terminal, and an optical transmission path optically coupling the transmitting and receiving terminals and having at least one rare-earth doped optical amplifier therein, a second optical amplifier is provided The second optical amplifier includes a first portion of the optical transmission path having a first end coupled to the transmitting terminal and a second end coupled to a first of the rare-earth doped optical amplifiers. In addition, the second optical amplifier includes a pump source providing pump energy to the first portion of the optical transmission path at one or more wavelengths that is less than a signal wavelength to provide Raman gain in the first portion at the signal wavelength.

Abstract: A method of developing a software product, including steps of: receiving sets of parameters (e.g., manifests) describing computing environments for a plurality of customers, at least some of said sets of parameters for some customers differing from others of said sets of parameters for other customers; receiving an indication from at least one of said customers of a bug or condition that occurs with said software product running under one of said sets of parameters; and testing said software product in a computing environment configured in accordance with said sets of parameters including at least said one of said sets of parameters indicated by said one of said customers. The sets of parameters can also be sent back to customers to help with disaster recovery. Also, a method of distributing said software product and servers that perform these methods.

Abstract: The present invention discloses a bicycle as an advertising and graphic display medium encompassing the frame and wheel disks as a whole. The bicycle and non-rotating wheel displays, front and back, traverse the landscape as one unit and while in a motionless state. The bicycle becomes a solid unit, frame and non-rotating display wheels become one surface.

Abstract: An undersea WDM optical transmission system is provided. The system includes first and second land-based cable stations, at least one of the cable stations includes power feed equipment (PFE) supplying electrical power to the cable at a voltage of no more than about 6 kv or less. The PFE is located in at least one of the cable stations. The system also includes an undersea WDM optical transmission cable having a length corresponding to those required in the undersea regional market. The cable includes at least one optical fiber pair for supporting bidirectional communication between the first and second cable stations. At least one repeater is located along the optical transmission cable. The repeater includes at least two optical amplifiers each providing optical gain to one of the optical fibers in the optical fiber pairs. The optical gain is in a range from about 12 to 20 dB.

Abstract: A retroreflective laminate sheeting has a viewing surface having a retroreflective layer which has a first cap-Y value of a viewing surface side thereof. A plurality of discrete pigmented indicia are disposed on the viewing surface side of the retroreflective layer. The pigmented indicia define a second cap-Y value of the viewing surface of the sheeting, the second cap-Y value being less than the first cap-Y value. One method of making a retroreflective sheeting includes forming a retroreflective layer on a web, the web moving in a web direction. The method includes applying a pigmented material proximate the retroreflective layer, the pigmented material preferably forming a plurality of parallel stripes oriented substantially in at least one of the web direction and a direction orthogonal to the web direction.

Abstract: The present invention describes a non-rotating display bicycle wheel cover assembly that remains absolutely upright in relation to the rotation of the bicycle wheel and in relation to a parked bicycle wheel. The invention consists of twin disk assemblies mounted to both sides of a conventional bicycle wheel and inturn to the front and rear of a bicycle frame. The disk assemblies are manufactured of lightweight inexpensive material that is formed to the convex shape of the outer surface of a bicycle wheel and includes an overmolded, captive friction bearing made of a high density, self lubricating plastic. A plastic retaining mechanism is secured to the outer disk fascia and a bicycle frame member to hold the disk in an upright position at all times whether the bicycle is in motion or in repose.

Abstract: An optical amplifier module is provided that contains at least one optical amplifier. The module includes an internal housing having an outer dimension substantially equal to an outer dimension of an internal fiber splice housing of an undersea optical fiber cable joint. The internal housing includes a pair of opposing end faces each having a retaining element for retaining the internal housing within an outer housing of the undersea optical fiber cable joint. The internal housing also includes a sidewall interconnecting the opposing end faces, which extends between the opposing end faces in a longitudinal direction. The sidewall, which is formed from a thermally conductive material, includes a receptacle portion having a plurality of thru-holes each being sized to receive a passive optical component employed in an optical amplifier.

Abstract: An undersea optical repeater is provided that includes a pressure vessel for use in an undersea environment. The pressure vessel has at least two cable-receiving elements for respectively receiving ends of optical cables that each includes an electrical conductor therein. At least one optical amplifier is located in the pressure vessel. The optical amplifier includes at least one electrical component adapted to receive electrical power from the electrical conductors in the optical cables. A dielectric envelope surrounds the pressure vessel to provide a hermetic seal therewith. The envelope includes a dielectric overmold surrounding at least a portion of the pressure vessel.

Abstract: The present invention is a Virtual Mail House System that is an Internet-based management of direct mail campaigns from creation through completion that enables real time status reporting for customers. It entails online storage of Databases (a list of addresses to which physical mailers are sent), an online Library (a list of either predefined or user-uploaded documents), a process for creating, managing and tracking the campaign that also maintains a complete history of all activities for both the customer and each record in the database, and fulfillment management and acknowledgement system. The system also provides online contact management which includes the function of maintaining a contact history. When utilizing the present virtual mail house system a user can create a contact database, create a mail campaign, and manage and track the campaign from beginning to end.

Abstract: The present invention describes a internally geared display bicycle wheel covers that rotate upon a gear cluster in relation to the rotation of the bicycle wheel. The invention consists of twin disk assemblies mounted to both sides of a conventional bicycle wheel and inturn to the front and rear of a bicycle frame. The disk assemblies are manufactured of lightweight inexpensive material that is formed to the convex shape of the outer surface of a bicycle wheel and includes an internal gear mechanism made of a high density, self lubricating plastic. Gear ratios may be changed to achieve a desired rotation of the outer display disk or geared as such to hold the disk in an upright position at all times whether the bicycle is in motion or in repose.

Abstract: An undersea optical repeater is provided. The repeater includes at least first and second pressure vessels for use in an undersea environment. Each of the pressure vessels includes a pressure housing and at least two cable receiving elements disposed on opposing ends of the pressure housing for respectively receiving ends of optical cables that each include an electrical conductor therein. The cable receiving elements are adapted to be in electrical contact with the respective electrical conductors in the optical cables. The pressure housing is adapted to provide electrical isolation between the respective cable receiving elements attached thereto. At least one optical amplifier is located in each of the pressure vessels. Each of the optical amplifiers includes at least one electrical component adapted to receive electrical power from the electrical conductors in the optical cables.

Abstract: An optical amplifier module is provided that contains at least one optical amplifier. The module includes an internal housing having an outer dimension substantially equal to an outer dimension of an internal fiber splice housing of an undersea optical fiber factory cable joint. The internal housing includes a pair of opposing end faces each having a retaining element for retaining the internal housing within an outer housing of the undersea optical fiber cable joint. The internal housing also includes a sidewall interconnecting the opposing end faces, which extends between the opposing end faces in a longitudinal direction. The sidewall includes a receptacle portion having a plurality of thru-holes each being sized to receive a passive optical component employed in an optical amplifier. The module also includes at least one circuit board on which reside electronics associated with the optical amplifier.

Abstract: A method for entering a market with high barriers to entry and a plurality of proprietary business elements includes converting at least one of the business elements into a universal business element that can accept a wide variety of inputs from other business elements, while converting a remaining one of the plurality of business elements to commoditized business elements. For example, one exemplary embodiment of the present invention employs an optical repeater that can accept any existing submarine cable, in combination with an optical line interface terminal that can accept existing terrestrial terminal equipment. Regarding market division, this embodiment is specifically limited to spans of less than 5000 kilometers, and preferably between 350 and 4000 kilometers, thereby straddling both the long-haul and short-haul markets while providing highly desirable services and capability.

Abstract: A pressure vessel is provided for use in an undersea environment. The pressure vessel including a pressure housing and at least two cable receiving elements disposed on opposing ends of the pressure housing for respectively receiving ends of optical cables that each include an electrical conductor therein, said cable receiving elements adapted to be in electrical contact with the respective electrical conductors in the optical cables. At least one optical amplifier is located in the pressure vessel. The optical amplifier includes at least one electrical component adapted to receive electrical power from the electrical conductors in the optical cables. The pressure vessel also includes an electrically insulating element electrically isolating at least one of the cable receiving elements from the pressure housing.

Abstract: In accordance with the present invention, a land-based cable station is provided for an undersea optical transmission system. The cable station includes submarine line terminal equipment (SLTE) for processing terrestrial traffic received from an external source, power feed equipment for supplying electrical power to active undersea components of the transmission system, an element management system for configuring and obtaining status information from the transmission system, and a cable termination box in which an undersea cable terminates. The SLTE includes terrestrial optical transmission equipment receiving the terrestrial traffic and generating optical signals in response thereto. The SLTE also includes an interface device providing signal conditioning to the optical signals received from the terrestrial optical transmission equipment so that the optical signals are suitable for transmission through the undersea optical transmission system.