Abstract: The present invention relates to a nucleic acid molecule encoding for IEX-1 polypeptide as a medicament. In a further aspect the present invention relates to a nucleic acid molecule encoding for IEX-1 polypeptide for the manufacture of a medicament for the treatment of gliomas.

Abstract: The present invention is directed to a composition of matter, in particular a food composition, dietary or food supplementation, and pharmaceutical composition, respectively. The composition of matter reduces the risk of neuropathy, neurodegenerative diseases including late-onset Alzheimer's disease, and cancer, in particular of pancreatic, esophageal, oropharyngolaryngeal, liver, colorectal, lung and/or breast cancer, in particular the drug and/or alcohol induced risk of said diseases. In this respect, the present invention is also directed to a composition of matter; in particular a food composition, dietary or food supplementation, and pharmaceutical composition, respectively, which supports and/or moderates the alcohol degradation process within the human body.

Abstract: The present invention relates to synthetic gag and gagpol genes optimized for high level expression via codon optimization and the uses thereof for the efficient generation of vector particles. The invention further relates to the generation of packaging cells and vaccines based on the synthetic gag and gagpol genes.

Abstract: The present invention relates to synthetic gag and gagpol genes optimized for high level expression via codon optimization and the uses thereof for the efficient generation of vector particles. The invention further relates to the generation of packaging cells and vaccines based on the synthetic gag and gagpol genes.

Abstract: The present invention is directed to a composition, in particular a food composition, or dietary supplementation which is active in respect to the support and/or the moderation of an alcohol degradation process within the human body. The present invention particularly addresses the problem of rapid alcohol degradation i.e. alcohol metabolism as may occur in most people of Non-Caucasian type genetic structure. In this regard, an object of the present invention is to achieve solutions which provide a reduction in the physiological stress in connection with the consumption of alcohol in particular for people with a predisposition towards rapid alcohol degradation. According to the present invention this object is attained by a food composition or dietary supplementation including the following substances: dextrose, Vitamin C, L-glutamine cysteine, riboflavin, succinic acid, fumaric acid, and coenzyme Q10, all substances in physiologically relevant doses in particular as disclosed.

Abstract: An operator backrest in combination with a materials handling vehicle is provided. The backrest may comprise a primary support pad and gripping structure located in at least one side portion of the primary support pad. The gripping structure may be substantially even with or extend above a surface of a portion of the primary support pad surrounding the gripping structure for engagement with an operator positioned on the materials handling vehicle.

Abstract: A materials handling vehicle is provided comprising a frame including an operator compartment having at least one entrance and a floorboard. The vehicle further comprises at least one step capable of being positioned across the entrance a spaced distance from the floorboard such that an operator may stand on the step when the step is positioned across the entrance to gain access to an elevated storage location.

Abstract: To provide a universally usable free-piston device with electric linear drive, comprising at least one piston receptacle with at least one piston device arranged for linear displacement in the piston receptacle, the piston device comprising a traveller device, and a stator device being arranged on the piston receptacle, and the at least one piston device being drivable under the action of a medium which expands in an expansion space, it is proposed that the piston stroke be variably adjustable via the linear drive such that the dead centers of the displacement of the piston device are definable.

Abstract: To provide a universally usable free-piston device with electric linear drive, comprising at least one piston receptacle with at least one piston device arranged for linear displacement in the piston receptacle, the piston device comprising a traveller device, and a stator device being arranged on the piston receptacle, and the at least one piston device being drivable under the action of a medium which expands in an expansion space, it is proposed that the piston stroke be variably adjustable via the linear drive such that the dead centers of the displacement of the piston device are definable.

Abstract: The present invention relates to synthetic gag and gagpol genes optimized for high level expression via codon optimization and the uses thereof for the efficient generation of vector particles. The invention further relates to the generation of packaging cells and vaccines based on the synthetic gag and gagpol genes.

Abstract: A microsensor system, in particular gas sensor system, is integrated on a single chip and includes a microsensor, preferably a resistive-film-sensor configuration, with a microheater, the latter preferably of essentially round, elliptic or polygonal structure. The microsensor is located on a thermally insulated semiconductor structure, e.g. a thin membrane. Further included or integrated on the chip may be one or more first circuits for controlling the microheater and/or second circuits for evaluating or processing the measured values obtained from the microsensor. The first circuits may include power and/or temperature controller for the microheater. The second circuits may include an A/D converter, a digital signal processor, a digital output interface for processing sensor signals and transferring them to external devices, and/or potentiostats to regulate the electrode potential applied to the gas-sensitive layer.

Abstract: An ablation arrangement (1) for the targeted production of local lesions in living tissue inside the body, particularly inside the heart, comprising at least one energy source (15), a plurality of energy uncoupling elements (11b to 11g) that are attached to a holding element (11a), a plurality of energy transmission lines (19.1) that connect the energy source or the energy sources to the energy uncoupling elements and switching elements (9.3) that are assigned to the energy transmission lines for setting up or interrupting a connection between the energy source and respectively one energy uncoupling element, with program control means (9.1) for a time-sequential actuation of at least some of the switching elements according to an ablation program.