Patents by Inventor Markus Sakari Kauppinen
Markus Sakari Kauppinen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20030054539Abstract: The present invention relates to enzyme preparations consisting essentially of an enzyme which has cellulytic activity and comprises a first amino acid sequence having the following sequence 1 (SEQ ID NO:79) Thr Arg Xaa Xaa Asp Cys Cys Xaa Xaa 1 2 3 4 5 6 7 8 9 Xaa Cys Xaa Trp Xaa 10 11 12 13 14Type: ApplicationFiled: December 10, 2001Publication date: March 20, 2003Applicant: Novozymes A/SInventors: Martin Schulein, Hanne Dela, Lene Nonboe Andersen, Soren Flensted Lassen, Markus Sakari Kauppinen, Lene Lange, Ruby Ilum Nielsen, Shinobu Takagi, Michiko Ihara
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Publication number: 20030032165Abstract: The present invention relates to novel isolated aspartic acid proteases and isolated nucleic acid sequences encoding such aspartic acid proteases. The present invention also relates to nucleic acid constructs, vectors and host cells comprising the nucleic acid sequences as well as to methods for producing and using the aspartic acid proteases.Type: ApplicationFiled: June 12, 2001Publication date: February 13, 2003Applicant: Novozymes A/SInventors: Wenping Wu, Peter Rahbek Ostergaard, Markus Sakari Kauppinen
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Patent number: 6514739Abstract: The inventors have isolated lysophospholipases from Aspergillus (A. niger and A. oryzae) having molecular masses of about 68 kDa and amino acid sequences of 600-604 amino acid residues. The novel lysophospholipases have only a limited homology to known amino acid sequences. The inventors also isolated genes encoding the novel enzymes and cloned them into E. coli strains.Type: GrantFiled: October 13, 2000Date of Patent: February 4, 2003Inventors: Hiroaki Udagawa, Torben Peter Frandsen, Tom Anton Busk Nielsen, Markus Sakari Kauppinen, Søren Christensen
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Publication number: 20030022807Abstract: The present invention relates to xyloglucanases belonging to family 5 of glycosyl hydrolases are derived from strains of Paenibacillus, especially from strains of Paenibacillus pabuli. The xyloglucanases show high performance in conventional liquid detergent compositions.Type: ApplicationFiled: March 1, 2001Publication date: January 30, 2003Applicant: Novozymes A/SInventors: Reinhard Wilting, Mads Eskelund Bjornvad, Markus Sakari Kauppinen, Martin Schulein, Hanne Dela
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Patent number: 6500658Abstract: An isolated or purified polypeptide having xyloglucanase activity which is obtained from a strain of the genus Malbranchea and has xyloglucanase activity in the pH range 4-11, measured at 50° C.; and/or a molecular mass of 25±10 kDa, as determined by SDS-PAGE; and/or an isoelectric point (pI) in the range 3-5; and/or an N-terminal sequence Ala-Asp-Phe-Cys-Gly-Gln-Xaa-Asp-Ser-Glu-Gln-Ser-Gly-Pro-Tyr-Ile-Val-Tyr-Asn-Asn-Leu is useful in industrial applications such as in laundry detergent compositions and for treatment of textiles.Type: GrantFiled: September 1, 2000Date of Patent: December 31, 2002Assignee: Novozymes, A/SInventors: Wenping Wu, Martin Schulein, Markus Sakari Kauppinen, Mary Ann Stringer
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Patent number: 6485954Abstract: The present invention relates to an enzyme with galactanase activity, a DNA construct encoding the enzyme with galactanase activity, a method of producing the enzyme, an enzyme composition comprising said enzyme with galactanase activity, and the use of said enzyme and enzyme composition for a number of industrial applications.Type: GrantFiled: November 28, 2000Date of Patent: November 26, 2002Assignee: Novozymes A/SInventors: Lene Venke Kofod, Markus Sakari Kauppinen, Lene Nonboe Andersen, Ib Groth Clausen, Anette Müllertz
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Publication number: 20020142438Abstract: The present invention relates to pectate lyases comprising the amino acid sequence Asn Leu Asn Ser Arg Val Pro (NLNSRVP) (SEQ ID NO: 2) belonging to Family 1 of polysaccharide lyases have good performance in industrial processes under neutral or alkaline conditions such as laundering and textile processing. The pectate lyase may be derivable from Bacillus species.Type: ApplicationFiled: February 7, 2002Publication date: October 3, 2002Applicant: Novozymes A/SInventors: Lene Nonboe Andersen, Martin Schulein, Hanne Dela, Niels Erik Krebs Lange, Mads Eskelund Bjornvad, Soren Moller, Sanne O. Schroder Glad, Markus Sakari Kauppinen, Kirk Schnorr, Lars Kongsbak
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Patent number: 6428993Abstract: The present invention relates to transglutaminases and transglutaminase preparations obtained from lower fungi belonging to the class Oomycetes. Unprecedented high-level expression is achievable by growing these coenocytium forming organisms, especially the strains Pythium sp., Pythium irregulare, Pythium dissotocum, Pythium periilum (or P. periplocum), Pythium torulosum, Pythium ultimum, Pythium aphanidermatum, Phytophthora cactorum, Phytophthora palmivora, Phytophthora porri, Phytophthora infestans, Phytoph-thora megasperma, Phytophthora cinnamomi and Phytophthora cryptogea. Arecombinant transglutaminase has been cloned and expressed, the enzyme and enzyme preparations being useful for cross-linking proteins, e.g. in flour, baked products, meat products, fish products, cosmetics, cheese, milk products, gelled food products and leather finishing, or as a glutaminase, e.g. in bread and other baked glutein-containing food products.Type: GrantFiled: June 24, 1997Date of Patent: August 6, 2002Assignee: Novozymes A/SInventors: Lisbeth Bech, Grethe Rasmussen, Torben Halkier, Mariko Okada, Lene Nonboe Andersen, Markus Sakari Kauppinen, Thomas Sandal
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Patent number: 6413559Abstract: The present invention relates to a 35 kDa enzyme exhibiting aminopeptidase activity which is derived from a fungal microorganism, a DNA construct comprising a DNA sequence encoding said enzyme, a recombinant expression vector comprising said DNA construct, and a cell comprising said DNA sequence. The present invention also provides a method for producing said enzyme exhibiting aminopeptidase activity, and an enzyme preparation comprising said enzyme, a bread-improving or dough-improving composition comprising the aminopeptidase of the invention. Finally the invention relates to the use of said enzyme exhibiting aminopeptidase activity or enzyme preparations or compositions thereof.Type: GrantFiled: November 22, 2000Date of Patent: July 2, 2002Assignee: Novozymes A/SInventors: Markus Sakari Kauppinen, Joan Qi Si, Tina Spendler, Claus Dambmann, Torben Halkier, Peter Rahbek Østergaard, Shamkant Anant Patkar, Kim Hansen
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Patent number: 6387690Abstract: The present invention relates to enzyme preparations consisting essentially of an enzyme which has cellulytic activity and comprises a first amino acid sequence consisting of 14 amino acid residues having the following sequence Thr Arg Xaa Xaa Asp Cys Cys Xaa Xaa Xaa Cys Xaa 1 2 3 4 5 6 7 8 9 10 11 12 Trp Xaa 13 14 and a second amino acid sequence consisting of 5 amino acid residues having the following sequence Trp Cys Cys Xaa Cys 1 2 3 4 5 wherein, in position 3 of the first sequence, the amino acid is Trp, Tyr or Phe; in position 4 of the first sequence, the amino acid is Trp, Tyr or Phe; in position 8 of the first sequence, the amino acid is Arg, Lys or His; inType: GrantFiled: January 13, 1999Date of Patent: May 14, 2002Assignee: Novozymes A/SInventors: Martin Schülein, Lene Nonboe Andersen, Søren Flensted Lassen, Markus Sakari Kauppinen, Lene Lange, Ruby Ilum Nielsen, Michiko Ihara, Shinobu Takagi
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Patent number: 6368843Abstract: A novel group of pectate lyases comprising the amino acid sequence Asn Leu Asn Ser Arg Val Pro (NLNSRVP) belonging to Family 1 of polysaccharide lyases have good performance in industrial processes under neutral or alkaline conditions such as laundering and textile processing. The pectate lyase may be derivable from Bacillus species.Type: GrantFiled: October 23, 2000Date of Patent: April 9, 2002Assignee: Novozymes A/SInventors: Lene Nonboe Andersen, Martin Schülein, Niels Erik Krebs Lange, Mads Eskelund Bjørnvad, Søren Møller, Sanne O. Schrøder Glad, Markus Sakari Kauppinen, Kirk Schnorr, Lars Kongsbak
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Patent number: 6329185Abstract: The present invention relates to an enzyme with galactanase activity, a DNA construct encoding the enzyme, a method of producing the enzyme, an enzyme composition comprising the enzyme, and the use of the enzyme and enzyme composition for a number of industrial applications.Type: GrantFiled: August 4, 1998Date of Patent: December 11, 2001Assignee: Novozymes A/SInventors: Lene Venke Kofod, Markus Sakari Kauppinen, Lene Nonboe Andersen, Ib Groth Clausen
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Patent number: 6270968Abstract: A method for providing a hybrid polypeptide having an activity of interest, by i) performing PCR amplification using an uncharacterized DNA sample and oligonucleotide primers with homology to one or more known genes encoding a polypeptide exhibiting said activity of interest, to obtain one or more PCR products, ii) linking the obtained PCR products to a 5′ structural gene sequence and a 3′ structural gene sequence, wherein the 5′ and 3′ structural gene sequences are derived from one or more genes encoding a polypeptide exhibiting said activity of interest, to form hybrid DNA sequences, iii) expressing the resulting hybrid DNA sequences, and iv) screening the hybrid polypeptides to identify a sequence encoding a polypeptide exhibiting said activity of interest or a related activity.Type: GrantFiled: November 5, 1998Date of Patent: August 7, 2001Assignee: Novozymes A/SInventors: Henrik Dalbøge, Thomas Sandal, Markus Sakari Kauppinen, Børge Diderichsen
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Patent number: 6242237Abstract: The present invention relates to an enzyme with galactanase activity, a DNA construct encoding the enzyme with galactanase activity, a method of producing the enzyme, an enzyme composition comprising the enzyme with galactanase activity, and the use of the galactanase enzyme and enzyme composition for a number of industrial applications.Type: GrantFiled: August 21, 1998Date of Patent: June 5, 2001Assignee: Novo Nordisk A/SInventors: Lene Venke Kofod, Markus Sakari Kauppinen, Lene Nonboe Andersen, Ib Groth Clausen, Anette Müllertz
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Patent number: 6228630Abstract: An enzyme preparation comprising (a) first enzyme with xylanase activity and (b) a second enzyme having cellulotytic, xylanolytic or pectinolytic activity and are supported by the specification.Type: GrantFiled: June 22, 2000Date of Patent: May 8, 2001Assignee: Novo Nordisk A/SInventors: Lene Venke Kofod, MArkus Sakari Kauppinen, Stephan Christgau, Hans Peter Heldt-Hansen, Henrik Dalbøge, Lene Nonboe Andersen, Joan Qi Si, Tina Sejersgåard Jacobsen, Niels Munk, Anette Müllertz
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Patent number: 6214598Abstract: An enzyme from Aspergillus aculeatus exhibiting endoglucanase activity encoded by the DNA sequence of SEQ ID NO:17 or 18, and useful for degrading plant cell walls.Type: GrantFiled: November 19, 1997Date of Patent: April 10, 2001Assignee: Novo Nordisk A/SInventors: Henrik Dalboege, Lene Nonboe Andersen, Lene Venke Kofod, Markus Sakari Kauppinen, Stephan Christgau
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Patent number: 6200792Abstract: The present invention relates to an enzyme exhibiting aminopeptidase activity, a method for producing said enzyme, an enzyme preparation containing said enzyme exhibiting aminopeptidase activity, and use of said enzyme for various industrial purposes.Type: GrantFiled: May 30, 2000Date of Patent: March 13, 2001Assignee: Novo Nordisk-A/S Novo AlleInventors: Markus Sakari Kauppinen, Joan Qi Si, Tina Spendler, Claus Dambmann, Torben Halkier, Peter Rahbek Østergaard, Shamkant Anant Patkar, Kim Hansen
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Patent number: 6197564Abstract: A DNA construct encoding an enzyme(s) exhibiting xylanase activity, which enzyme is immunologically reactive with antibody raised against a purified xylanase derived from Aspergillus aculealus, CBS 101.43, recombinant vectors and cells comprising said construct and a method for producing said enzyme using said cell comprising said construct.Type: GrantFiled: December 22, 1998Date of Patent: March 6, 2001Assignee: Novo Nordisk A/SInventors: Lene Venke Kofod, MArkus Sakari Kauppinen, Stephan Christgau, Hans Peter Heldt-Hansen, Henrik Dalbøge, Lene Nonboe Andersen, Joan Qi Si, Tina Sejersgård Jacobsen, Niels Munk, Anette Müllertz
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Patent number: 6190905Abstract: An isolated and purified enzyme exhibiting protease activity at a pH of 4-7 which exhibits protease in 5% hydrogen peroxide and which is encoded by a DNA sequence which hybridizes to a DNA sequence depicted in SEQ ID NO: 1 or 2. Methods are described for using the protease compositions in reducing vescosity, cleaning contact lenses, baking, and preparing animal feed.Type: GrantFiled: September 29, 1999Date of Patent: February 20, 2001Inventors: Henrik Dalbøge, Stephan Christgau, Lene Nonboe Andersen, Lene Venke Kofod, Markus Sakari Kauppinen, Jack Bech Nielsen, Claus Dambmann
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Patent number: 6187580Abstract: A novel group of pectate lyases comprising the amino acid sequence Asn Leu Asn Ser Arg Val Pro (NLNSRVP) belonging to Family 1 of polysaccharide lyases have good performance in industrial processes under neutral or alkaline conditions such as laundering and textile processing. The pectate lyase are derivable from Bacillus species.Type: GrantFiled: November 24, 1998Date of Patent: February 13, 2001Assignee: Novo Nordisk A/SInventors: Lene Nonboe Andersen, Martin Schülein, Niels Erik Krebs Lange, Mads Eskelund Bjørnvad, Søren Møller, Sanne O. Schrøder Glad, Markus Sakari Kauppinen, Kirk Schnorr, Lars Kongsbak