Abstract: The aim of the invention is to allow a reliable quantification and classification of brake abrasion of a brake system of a vehicle and simultaneously reduce the complexity in a practical application. This is achieved by a measuring rim with a rim interior, in which a collecting housing is arranged that extends in the circumferential direction of the measuring rim over an extension angle (?). A collecting housing interior is formed in the collecting housing, and the collecting housing is at least partly open towards the collecting housing interior on a radially inner circumferential surface extending in the circumferential direction of the measuring rim. A discharge area is provided on the rim flange on the measuring rim, and a collecting channel which connects the collecting housing interior of the collecting housing to the discharge area is provided on the measuring rim.

Abstract: The present invention relates to bispecific anti-CCL2 antibodies binding to two different epitopes on human CCL2, pharmaceutical compositions thereof, their manufacture, and use as medicaments for the treatment of cancers, inflammatory, autoimmune and ophthalmologic diseases.

Abstract: The present disclosure relates to a pyrotechnic object, in particular an irritation body, irritation projectile or ammunition, comprising an ignition device, comprising a delay chamber extending along a delay path, in which chamber a delay charge is accommodated, and comprising at least one and preferably a plurality of effect chambers in which or in each of which an effect charge to be ignited is accommodated, wherein the delay chamber is transversely connected to a respective effect chamber via a respective over-ignition opening which branches off from the delay chamber and forms an over-ignition path, wherein in the case of a plurality of effect chambers the plurality of over-ignition openings are arranged successively downstream along the delay path in the order of the effect charges to be ignited.

Abstract: A composition is provided comprising: a) polyvinylchloride, b) inorganic solid particles, and c) a polymer having a polyether segment, wherein at least 60 mol-% of the end groups of the polymer are selected from the group consisting of carboxylic acid groups and hydroxyl groups, and wherein at least a part of the end groups of the polymer is a carboxylic acid group, wherein the carboxylic acid end groups are linked to the polyether segment via a linking segment comprising an ester group.

Abstract: The present invention relates to bispecific anti-CCL2 antibodies binding to two different epitopes on human CCL2, pharmaceutical compositions thereof, their manufacture, and use as medicaments for the treatment of cancers, inflammatory, autoimmune and ophthalmologic diseases.

Abstract: Placing a first side of an active thermal interposer device of a thermal management head against a device under test (DUT). Disposing a cold plate against a second side of the active thermal interposer. The DUT includes a plurality of modules and the active thermal interposer device includes a plurality of zones, each zone of the plurality of zones corresponding to a respective module of the plurality of modules and operable to be selectively heated. Receiving a respective set of inputs corresponding to each zone of the plurality of zones. Performing thermal management of the plurality of modules of the DUT by separately controlling temperature of each zone of the plurality of zones by controlling a supply of coolant to the cold plate, and individually controlling heating of each zone of the plurality of zones.

Abstract: Placing a first side of an active thermal interposer device of a thermal management head against a device under test (DUT). Disposing a cold plate against a second side of the active thermal interposer. The DUT includes a die and the active thermal interposer device includes a plurality of zones, each zone of the plurality of zones corresponding to a respective module of the plurality of modules and operable to be selectively heated. Receiving a respective set of inputs corresponding to each zone of the plurality of zones. Performing thermal management of the plurality of modules of the DUT by separately controlling temperature of each zone of the plurality of zones by controlling a supply of coolant to the cold plate, and individually controlling heating of each zone of the plurality of zones.

Abstract: Embodiments of the present invention provide an automated test equipment (a “tester”) for testing a device under test, including a bidirectional dedicated real-time handler interface. Some embodiments include an interface having a trigger function, a fixed endpoint interface, an interface arranged on a test head, and/or a number of lines/communication channels adapted to a specific communication task, without separate signal lines, for example. The bidirectional dedicated real-time handler interface can be used to transmit a multiple signals, such as a thermal control signal, synchronization signal, and/or other information to the handler in real-time, and the transmitted signals can be test site specific. The real-time signaling advantageously improves testing accuracy and efficiency.

Abstract: Embodiments of the present invention provide an automated test equipment (a “tester”) for testing a device under test, including a bidirectional dedicated real-time handler interface. Some embodiments use the bidirectional dedicated real-time handler interface to transmit a synchronization signal between the handler and the automated test equipment to synchronize a function of the handler in real-time, which advantageously improves testing efficiency and accuracy.

Abstract: The present disclosure relates to aspirating smoke detectors (ASD). In an ASD, ambient air is aspirated and is fed to a fire detector unit for determining a signal level. For normal operation, the suction power is set to a nominal airflow value and this is increased from a minimum signal level value in order to shorten the transport time of aspirated smoke through the suction pipe to the fire detector unit. In some embodiments, an interruption signal provided for normal operation is output if the airflow exceeds an upper limit value for a minimum period. Independently thereof, the suction power is increased from the minimum signal level value only to the extent that the airflow does not exceed the upper limit value. Or, regardless thereof, the suction power is increased only for a timespan smaller than the minimum period in which the airflow exceeds the upper limit value.

Abstract: Embodiments of the present invention provide an automated test equipment (a “tester”) for testing a device under test, including a bidirectional dedicated real-time handler interface. Some embodiments include an interface having a trigger function, a fixed endpoint interface, an interface arranged on a test head, and/or a number of lines/communication channels adapted to a specific communication task, without separate signal lines, for example. The bidirectional dedicated real-time handler interface can be used to transmit a synchronization signal or other information to the handler in real-time, and the transmitted signal can be test site specific. The real-time signaling advantageously improves testing accuracy and efficiency.

Abstract: Disposing a DUT between a cold plate and an active thermal interposer device of the thermal management head. The DUT includes a plurality of modules and the active thermal interposer device includes a plurality of zones, each zone of the plurality of zones corresponding to a respective module of the plurality of modules and operable to be selectively heated. Receiving a respective set of inputs corresponding to each zone of the plurality of zones. Performing thermal management of the plurality of modules of the DUT by separately controlling temperature of each zone of the plurality of zones by controlling a supply of coolant to a cold plate, and individually controlling heating of each zone of the plurality of zones.

Abstract: The present invention relates to 1,3-thiazol-2-yl substituted benzamide compounds of general formula (I) as described and defined herein, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neurogenic disorder, as a sole agent or in combination with other active ingredients.

Abstract: Disposing a DUT between a cold plate and an active thermal interposer device of the thermal management head. The DUT includes a plurality of modules and the active thermal interposer device includes a plurality of zones, each zone of the plurality of zones corresponding to a respective module of the plurality of modules and operable to be selectively heated. Receiving a respective set of inputs corresponding to each zone of the plurality of zones. Performing thermal management of the plurality of modules of the DUT by separately controlling temperature of each zone of the plurality zones by controlling a supply of coolant to a cold plate, and individually controlling heating of each zone of the plurality zones.

Abstract: The present invention covers P2X3 inhibitor compounds of general formula (I) in which R1 and R2 are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of neurogenic disorders, as a sole agent or in combination with other active ingredients.

Abstract: A power supply is configured to perform an at least partial compensation of a voltage variation caused by a load change using a voltage variation compensation mechanism which is triggered in response to an expected load change. An Automated test equipment for testing a device under test comprises a power supply, which is configured to supply the device under test. The automated test equipment comprises a pattern generator configured to provide one or more stimulus signals for the device under test. The power supply is configured to perform an at least partial compensation of a voltage variation caused by a load change using a voltage variation compensation mechanism which is activated in synchronism with one or more of the stimulus signals and/or in response to one or more response data signals from the device under test. Corresponding methods and a computer program are also described.

Abstract: The present disclosure relates to aspirating smoke detectors (ASD). In an ASD, ambient air is aspirated and is fed to a fire detector unit for determining a signal level. For normal operation, the suction power is set to a nominal airflow value and this is increased from a minimum signal level value in order to shorten the transport time of aspirated smoke through the suction pipe to the fire detector unit. In some embodiments, an interruption signal provided for normal operation is output if the airflow exceeds an upper limit value for a minimum period. Independently thereof, the suction power is increased from the minimum signal level value only to the extent that the airflow does not exceed the upper limit value. Or, regardless thereof, the suction power is increased only for a timespan smaller than the minimum period in which the airflow exceeds the upper limit value.

Abstract: The present invention is related to agonist of adiponectin receptor 1 (AdipoR1) and/or adiponectin receptor 2 (AdipoR2) for the treatment and/or prevention of polycystic ovary syndrome (PCOS).

Abstract: Disposing a DUT between a cold plate and an active thermal interposer device of the thermal management head. The DUT includes a plurality of modules and the active thermal interposer device includes a plurality of zones, each zone of the plurality of zones corresponding to a respective module of the plurality of modules and operable to be selectively heated. Receiving a respective set of inputs corresponding to each zone of the plurality of zones. Performing thermal management of the plurality of modules of the DUT by separately controlling temperature of each zone of the plurality zones by controlling a supply of coolant to a cold plate, and individually controlling heating of each zone of the plurality zones.

Abstract: The present invention covers substituted. Pyrazolo-pyrrolo-pyrimidine-dione (PPPD) compounds of general formula (I): in which R1, R2 and R3 are as defined herein, methods of preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of neurogenic diseases, as a sole agent or in combination with other active ingredients.