Patents by Inventor Martin Kruger

Martin Kruger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6747046
    Abstract: Substituted N-(1,4,5,6-tetrahydro-cyclopentapyrazol-3-yl) derivatives, their production, as well as intermediate products for their production, and the use as pharmaceutical agents for treating various diseases are described.
    Type: Grant
    Filed: September 25, 2002
    Date of Patent: June 8, 2004
    Assignee: Schering Aktiengesellschaft
    Inventors: Martin Krüger, Olaf Prien, Andreas Steinmeyer, Jörg Kroll, Alexander Ernst, Gerhard Siemeister, Martin Haberey, Jens Hoffmann
  • Publication number: 20040078745
    Abstract: In a method for error correcting a data signal that is transmitted via a channel and contains data blocks with associated error checking information, the data signal is first equalized, with calculated soft-bit information. In a subsequent step, the error checking information is evaluated with respect to the data block. If the evaluation of the error checking information shows that a single bit error is present in one message bit, the single bit error is corrected only when a condition that is dependent on the soft-bit information is satisfied.
    Type: Application
    Filed: August 28, 2003
    Publication date: April 22, 2004
    Inventors: Martin Kruger, Michael Weber, Xiaofeng Wu, Bin Yang
  • Publication number: 20040063737
    Abstract: This invention relates to 2-heteroaryl-pyrimidine derivatives of general formula I as inhibitors of the cyclin-dependent kinases, their production as well as their use as medications for treating various diseases.
    Type: Application
    Filed: October 27, 2003
    Publication date: April 1, 2004
    Applicant: Schering AG
    Inventors: Ulrich Lucking, Martin Kruger, Rolf Jautelat, Olaf Prien, Gerhard Siemeister, Alexander Ernst
  • Publication number: 20030212121
    Abstract: Substituted N-(1,4,5,6-tetrahydro-cyclopentapyrazol-3-yl) derivatives, their production, as well as intermediate products for their production, and the use as pharmaceutical agents for treating various diseases are described.
    Type: Application
    Filed: September 25, 2002
    Publication date: November 13, 2003
    Inventors: Martin Kruger, Olaf Prien, Andreas Steinmeyer, Jorg Kroll, Alexander Ernst, Gerhard Siemeister, Martin Haberey, Jens Hoffman
  • Publication number: 20030179834
    Abstract: Only a single, standard-independent clock rate is generated in a signal processor or a signal processing structure, and correspondingly only precisely one clock frequency generator is then arranged on the chip. The signal processing path includes at least one controllable, asynchronous decimator for transposing the reception signals present in a uniform time frame into a respective standard-specific time frame. This enables signals of a variety of mobile phone standards to be processed.
    Type: Application
    Filed: March 14, 2003
    Publication date: September 25, 2003
    Inventors: Martin Kruger, Dietmar Wenzel
  • Publication number: 20030176469
    Abstract: The invention relates to substituted anthranylalkyl and cycloalkyl amides of general formula (I) and to their use as medicaments for treating diseases caused by persistent angiogenesis.
    Type: Application
    Filed: May 9, 2003
    Publication date: September 18, 2003
    Inventors: Dieter Seidelmann, Martin Kruger, Eckhard Ottow, Andreas Huth, Karl-heinz Thierauch, Andreas Menrad, Martin Haberey
  • Publication number: 20030064992
    Abstract: 1
    Type: Application
    Filed: June 26, 2002
    Publication date: April 3, 2003
    Inventors: Karl-Heinz Altmann, Guido Bold, Pascal Furet, Paul William Manley, Jeanette Marjorie Wood, Stefano Ferrari, Francesco Hofmann, Jurgen Mestan, Andreas Huth, Martin Kruger, Dieter Seidelmann, Andreas Menrad, Martin Haberey, Karl-Heinz Thierauch
  • Patent number: 6448277
    Abstract: Described are compounds of formula (I), wherein W is O or S; X is NR8; Y is CR9R10—(CH2)n wherein R9 and R10 are independently of each other hydrogen or lower alkyl, and n is an integer of from and including 0 to and including 3; or Y is S02; R1 is aryl; R2 is a mono- or bicyclic heteroaryl group comprising one or more ring nitrogen atoms with the exception that R2 cannot represent 2-phthalimidyl, and in case of Y=SO2 cannot represent 2,1,3-benzothiadiazol-4-yl; any of R3, R4, R5 and R6, independently of the other, is H or a substituent other than hydrogen; and R7 and R8, independently of each other, are H or lower alkyl; or a N-oxide or a pharmaceutically acceptable salt thereof for the preparation of a pharmaceutical product for the treatment of a neoplastic disease which responds to an inhibition of the VEGF receptor tyrosine kinase activity. The compounds of formula (I) can be used for the treatment e.g.
    Type: Grant
    Filed: May 7, 2001
    Date of Patent: September 10, 2002
    Assignees: Novartis AG, Schering Aktiengesellschaft
    Inventors: Karl-Heinz Altmann, Guido Bold, Pascal Furet, Paul William Manley, Jeanette Marjorie Wood, Stefano Ferrari, Francesco Hofmann, Jürgen Mestan, Andreas Huth, Martin Krüger, Dieter Seidelmann, Andreas Menrad, Martin Haberey, Karl-Heinz Thierauch
  • Publication number: 20020019414
    Abstract: 1
    Type: Application
    Filed: May 7, 2001
    Publication date: February 14, 2002
    Inventors: Karl-Heinz Altmann, Guido Bold, Pascal Furet, Paul William Manley, Jeanette Marjorie Wood, Stefano Ferrari, Francesco Hofmann, Jurgen Mestan, Andreas Huth, Martin Kruger, Dieter Seidelmann, Andreas Menrad, Martin Haberey, Karl-Heinz Thierauch
  • Patent number: 6288065
    Abstract: The disclosure relates to quinoxaline derivates of Formula I wherein R1, R4, R5, R6, R7 and R8 are defined in the disclosure, as well as their production and use in medicinal agents.
    Type: Grant
    Filed: June 23, 1998
    Date of Patent: September 11, 2001
    Assignee: Schering Aktiengeseellschaft
    Inventors: Andreas Huth, Ralph Schmiechen, Ilse Beetz, Ingrid Schumann, Lechoslaw Turski, Peter Andreas Loschmann, David Norman Stephens, Dieter Seidelmann, Martin Kruger, Dieter Rahtz, Peter Holscher
  • Patent number: 6143733
    Abstract: Quinoxalinedione derivatives ##STR1## as well as their production and use in pharmaceutical agents are described.
    Type: Grant
    Filed: May 29, 1997
    Date of Patent: November 7, 2000
    Assignee: Schering Aktiengesellschaft
    Inventors: Andreas Huth, Martin Kruger, Eckhard Ottow, Dieter Seidelmann, Graham H Jones, Herbert Schneider, Lechoslaw Turski
  • Patent number: 6136805
    Abstract: Quinoxalinedione derivatives of formula (I) ##STR1## are described, and their use in pharmaceutical agents.
    Type: Grant
    Filed: February 24, 1998
    Date of Patent: October 24, 2000
    Assignee: Scnering Aktiengesellschaft
    Inventors: Andreas Huth, Martin Kruger, Eckhard Ottow, Dieter Seidelmann, Roland Neuhaus, Herbert Schneider, Lechoslaw Turski
  • Patent number: 6057304
    Abstract: The disclosure relates to quinoxaline derivatives of Formula I ##STR1## wherein R.sup.1, R.sup.4, R.sup.5, R.sup.6, R.sup.7 and R.sup.8 are as defined in the disclosure, as well as their production and use in medicinal agents.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: May 2, 2000
    Assignee: Schering Aktiengesellschaft
    Inventors: Andreas Huth, Ralph Schmiechen, Ilse Beetz, Ingrid Schumann, Lechoslaw Turski, Peter Andreas Loschmann, David Norman Stephens, Dieter Seidelmann, Martin Kruger, Dieter Rahtz, Peter Holscher
  • Patent number: 5750526
    Abstract: Pyrido?1,2,3-de!quinoxaline derivatives of formula I ##STR1## in which R.sup.1, R.sup.2 and R.sup.3 each mean hydrogen, --POXY, halogen or --COR,R.sup.4 means hydrogen or OH,R.sup.5, R.sup.6 and R.sup.7 are the same or different and mean hydrogen, halogen, nitro, NR.sup.12 R.sup.13, cyano, CF.sub.3, C.sub.1-6 alkyl, C.sub.1-4 alkoxy, orR.sup.5 and R.sup.6 or R.sup.6 and R.sup.7 represent a fused benzene ring, and means a single or double bond,are described as well as their production and use in pharmaceutical agents.
    Type: Grant
    Filed: December 27, 1995
    Date of Patent: May 12, 1998
    Assignee: Schering Aktiengesellschaft
    Inventors: Martin Kruger, Werner Seelen, Lechoslaw Turski
  • Patent number: 5698555
    Abstract: Hetaryloxy-.beta.-carbolines of formula I ##STR1## in which R.sup.A means a triazine or benzocondensed hetaryl radical with 1-2 nitrogen atoms optionally substituted with halogen, C.sub.1-6 alkyl, C.sub.1-6 alkoxy, C.sub.1-6 alkylthio, trifluoromethyl or SO.sub.2 --R.sup.1 or a 5- or 6-membered hetaryl radical with 1-2 nitrogen atoms substituted with halogen, C.sub.1-6 alkyl, C.sub.1-6 alkoxy, C.sub.1-6 alkylthio, trifluoromethyl or SO.sub.2 --R.sup.1are useful pharmaceutical agents.
    Type: Grant
    Filed: July 11, 1994
    Date of Patent: December 16, 1997
    Assignee: Schering Aktiengesellschaft
    Inventors: Martin Kruger, Andreas Huth, Dieter Seidelmann, Herbert Schneider, Lechoslaw Turski, David Norman Stephens
  • Patent number: 5350750
    Abstract: .beta.-carboline-3-hydroxyalkylcarboxylic acid ester derivatives of formula I ##STR1## in which R.sup.A, n, R.sup.4 and R.sup.3, have the meaning indicated in the claims, as well as their production and their use in pharmaceutical agents are described.
    Type: Grant
    Filed: March 1, 1993
    Date of Patent: September 27, 1994
    Assignee: Schering Aktiengesellschaft
    Inventors: Andreas Huth, Martin Kruger, Dieter Seidelmann, Ralph Schmiechen, Werner Krause, Herbert Schneider, Lechoslaw Turski
  • Patent number: 5348958
    Abstract: Hetaryloxy-.beta.-carbolines of formula I ##STR1## in which R.sup.A means a benzocondensed hetaryl radical with 1-2 nitrogen atoms optionally substituted with halogen, C.sub.1-6 alkyl, C.sub.1-6 alkoxy, C.sub.1-6 alkylthio, trifluoromethyl or SO.sub.2 --R.sup.1 or a 5- or 6-membered hetaryl radical with 1-2 nitrogen atoms substituted with halogen, C.sub.1-6 alkyl, C.sub.1-6 alkoxy, C.sub.1-6 alkylthio, trifluoromethyl or SO.sub.2 --R.sup.1 are useful pharmaceutical agents.
    Type: Grant
    Filed: June 5, 1992
    Date of Patent: September 20, 1994
    Assignee: Schering Aktiengesellschaft
    Inventors: Martin Kruger, Andreas Huth, Dieter Seidelmann, Herbert Schneider, Lechoslaw Turski, David N. Stephens
  • Patent number: 5256682
    Abstract: 4-Isoxazolyl-imidazole derivatives of formula I ##STR1## in which R.sup.1, R.sup.2, R.sup.3 and R.sup.4 have the meanings indicated, as well as their production and use in pharmaceutical agents, are described.
    Type: Grant
    Filed: April 13, 1992
    Date of Patent: October 26, 1993
    Assignee: Schering Aktiengesellschaft
    Inventors: Martin Kruger, Rolf Russe, Herbert Schneider, Ralph Schmiechen, Lechoslaw Turski
  • Patent number: 5254563
    Abstract: Compounds of formula I ##STR1## in which R.sup.A, B (which is CR.sup.4) and R.sup.3 and have the meaning indicated in the application, as well as their production and their use in pharmaceutical agents, are described.
    Type: Grant
    Filed: October 23, 1991
    Date of Patent: October 19, 1993
    Assignee: Schering Aktiengesellschaft
    Inventors: Andreas Huth, Martin Kruger, Dieter Rahtz, Dieter Seidelmann, Ralph Schmiechen, Lechoslaw Turski, John S. Andrews, Herbert H. Schneider
  • Patent number: 4959094
    Abstract: The invention relates to new 1-chloropyrimidinyl-1H-1,2,4-triazol-3-sulphonamides of the general formual I ##STR1## in which A, R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 have the meanings given in the description, processes for their preparation and their use as herbicides.
    Type: Grant
    Filed: April 19, 1989
    Date of Patent: September 25, 1990
    Assignee: Schering Aktiengesellschaft
    Inventors: Peter Wegner, Martin Kruger, Gerhard Johann, Reinhart Rusch, Richard Rees, John Head, Graham Rowson