Patents by Inventor Mary Ann Franden
Mary Ann Franden has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11091782Abstract: Non-naturally occurring Zymomonas strains useful for the production of 2,3-butanediol are provided.Type: GrantFiled: October 29, 2018Date of Patent: August 17, 2021Assignee: Alliance for Sustainable Energy, LLCInventors: Min Zhang, Yat-Chen Chou, Mary Ann Franden, Michael E. Himmel
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Patent number: 11021721Abstract: Presented herein are genetically engineered Pseudomonas strains capable of metabolizing ethylene glycol and producing polyhydroxyalkanoates.Type: GrantFiled: July 20, 2018Date of Patent: June 1, 2021Assignees: Alliance for Sustainable Energy, LLC, University of Stuttgart, UT-Battelle, LLCInventors: Gregg Tyler Beckham, Mary Ann Franden, Lahiru N. Jayakody, Nick Johannes Petrus Wierckx, Janosch Alexander Klebensberger, Lars Mathias Blank, Wing-Jin Li, Bernhard Hauer, Nicholas S. Cleveland, William E. Michener, Jason Michael Whitham
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Patent number: 10337034Abstract: This disclosure relates to compositions and methods for converting biomass to various chemical intermediates and final products including fuels. Aspects include the depolymerization of lignin, cellulose, and hemicellulose to a wide slate of depolymerization compounds that can be subsequently metabolized by genetically modified bacterium, and converted to cis,cis-muconic acid. Other aspects include the use of monometallic catalysts for converting the cis,cis-muconic acid to commodity chemicals and fuels, for example adipic acid and/or nylon.Type: GrantFiled: April 27, 2018Date of Patent: July 2, 2019Assignee: Alliance for Sustainable Energy, LLCInventors: Gregg Tyler Beckham, Christopher W. Johnson, Derek Richard Vardon, Mary Ann Franden
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Publication number: 20190153483Abstract: Non-naturally occurring Zymomonas strains useful for the production of 2,3-butanediol are provided.Type: ApplicationFiled: October 29, 2018Publication date: May 23, 2019Inventors: Min ZHANG, Yat-Chen CHOU, Mary Ann FRANDEN, Michael E. HIMMEL
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Patent number: 10266852Abstract: Disclosed herein are methods for the production of fuels, chemicals, or materials from biomass-derived lignin, cellulose, and hemicellulose. Also provided are methods for the production of polyhydroxyalkanoates from lignocellulosic biomass and the subsequent thermal and catalytic conversion of polyhydroxyalkanoates to hydrocarbons. In addition, methods for the production of ethanol from the fermentation of polysaccharides are described.Type: GrantFiled: December 8, 2014Date of Patent: April 23, 2019Assignees: Alliance for Sustainable Energy, LLC, The Board of Trustees of the University of IllinoisInventors: Gregg T. Beckham, Jeffrey G. Linger, Derek R. Vardon, Michael T. Guarnieri, Eric M. Karp, Mary Ann Franden, Christopher W. Johnson, Timothy J. Strathmann, Philip T. Pienkos
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Publication number: 20190024126Abstract: Presented herein are genetically engineered Pseudomonas strains capable of metabolizing ethylene glycol and producing polyhydroxyalkanoates.Type: ApplicationFiled: July 20, 2018Publication date: January 24, 2019Inventors: Gregg Tyler BECKHAM, Mary Ann FRANDEN, Lahiru N. JAYAKODY, Nick Johannes Petrus WIERCKX, Janosch Alexander KLEBENSBERGER, Lars Mathias BLANK, Wing-Jin LI, Bernhard HAUER, Nicholas S. CLEVELAND, William E. MICHENER
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Publication number: 20180371502Abstract: Disclosed herein are methods for the production of fuels, chemicals, or materials from biomass-derived lignin, cellulose, and hemicellulose. Also provided are methods for the production of polyhydroxyalkanoates from lignocellulosic biomass and the subsequent thermal and catalytic conversion of polyhydroxyalkanoates to hydrocarbons. In addition, methods for the production of ethanol from the fermentation of polysaccharides are described.Type: ApplicationFiled: December 8, 2014Publication date: December 27, 2018Inventors: Gregg T. BECKHAM, Jeffrey G. LINGER, Derek R. VARDON, Michael T. GUARNIERI, Eric M. KARP, Mary Ann FRANDEN, Christopher W. JOHNSON, Timothy J. STRATHMANN, Philip T. PIENKOS
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Publication number: 20180291405Abstract: This disclosure relates to compositions and methods for converting biomass to various chemical intermediates and final products including fuels. Aspects include the depolymerization of lignin, cellulose, and hemicellulose to a wide slate of depolymerization compounds that can be subsequently metabolized by genetically modified bacterium, and converted to cis,cis-muconic acid. Other aspects include the use of monometallic catalysts for converting the cis,cis-muconic acid to commodity chemicals and fuels, for example adipic acid and/or nylon.Type: ApplicationFiled: April 27, 2018Publication date: October 11, 2018Inventors: Gregg Tyler BECKHAM, Christopher W. JOHNSON, Derek Richard VARDON, Mary Ann FRANDEN
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Patent number: 10017792Abstract: This disclosure relates to compositions and methods for converting biomass to various chemical intermediates and final products including fuels. Aspects include the depolymerization of lignin, cellulose, and hemicellulose to a wide slate of depolymerization compounds that can be subsequently metabolized by genetically modified bacterium, and converted to cis,cis-muconic acid. Other aspects include the use of monometallic catalysts for converting the cis,cis-muconic acid to commodity chemicals and fuels, for example adipic acid and/or nylon.Type: GrantFiled: July 20, 2015Date of Patent: July 10, 2018Assignee: Alliance for Sustainable Energy, LLCInventors: Gregg T. Beckham, Christopher W. Johnson, Derek R. Vardon, Mary Ann Franden
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Publication number: 20170044554Abstract: An L-arabinose utilizing yeast strain is provided for the production of ethanol by introducing and expressing bacterial araA, araB and araD genes, L-arabinose transporters are also introduced into the yeast to enhance the uptake of arabinose. The yeast carries additional genomic mutations enabling it to consume L-arabinose, even as the only carbon source, and to produce ethanol. A yeast strain engineered to metabolize arabinose through a novel pathway is also disclosed. Methods of producing ethanol include utilizing these modified yeast strains.Type: ApplicationFiled: September 18, 2014Publication date: February 16, 2017Inventors: Min ZHANG, Arjun SINGH, Pirkko SUOMINEN, Eric KNOSHAUG, Mary Ann FRANDEN, Eric JARVIS
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Publication number: 20160017381Abstract: This disclosure relates to compositions and methods for converting biomass to various chemical intermediates and final products including fuels. Aspects include the depolymerization of lignin, cellulose, and hemicellulose to a wide slate of depolymerization compounds that can be subsequently metabolized by genetically modified bacterium, and converted to cis,cis-muconic acid. Other aspects include the use of monometallic catalysts for converting the cis,cis-muconic acid to commodity chemicals and fuels, for example adipic acid and/or nylon.Type: ApplicationFiled: July 20, 2015Publication date: January 21, 2016Inventors: Gregg T. Beckham, Christopher W. Johnson, Derek R. Vardon, Mary Ann FRANDEN
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Patent number: 9206445Abstract: Disclosed herein are biocatalysts for the production of biofuels, including microorganisms that contain genetic modifications conferring tolerance to growth and fermentation inhibitors found in many cellulosic feedstocks. Methods of converting cellulose-containing materials to fuels and chemicals, as well as methods of fermenting sugars to fuels and chemicals, using these biocatalysts are also disclosed.Type: GrantFiled: April 29, 2014Date of Patent: December 8, 2015Assignee: Alliance for Sustainable Energy, LLCInventors: Shihui Yang, Jeffrey Linger, Mary Ann Franden, Philip T. Pienkos, Min Zhang
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Publication number: 20140342421Abstract: Disclosed herein are biocatalysts for the production of biofuels, including microorganisms that contain genetic modifications conferring tolerance to growth and fermentation inhibitors found in many cellulosic feedstocks. Methods of converting cellulose-containing materials to fuels and chemicals, as well as methods of fermenting sugars to fuels and chemicals, using these biocatalysts are also disclosed.Type: ApplicationFiled: April 29, 2014Publication date: November 20, 2014Applicant: Alliance for Sustainable Energy, LLCInventors: Shihui YANG, Jeffrey LINGER, Mary Ann FRANDEN, Philip T. PIENKOS, Min ZHANG
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Patent number: 8841090Abstract: An L-arabinose utilizing yeast strain is provided for the production of ethanol by introducing and expressing bacterial araA, araB and araD genes. L-arabinose transporters are also introduced into the yeast to enhance the uptake of arabinose. The yeast carries additional genomic mutations enabling it to consume L-arabinose, even as the only carbon source, and to produce ethanol. A yeast strain engineered to metabolize arabinose through a novel pathway is also disclosed. Methods of producing ethanol include utilizing these modified yeast strains.Type: GrantFiled: January 17, 2013Date of Patent: September 23, 2014Assignee: Alliance for Sustainable Energy, LLCInventors: Min Zhang, Arjun Singh, Pirkko Suominen, Eric Knoshaug, Mary Ann Franden, Eric Jarvis
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Patent number: 8465961Abstract: Strains of xylose utilizing Zymomonas with improved xylose utilization and ethanol production during fermentation in stress conditions were obtained using an adaptation method. The adaptation involved continuously growing xylose utilizing Zymomonas in media containing high sugars, acetic acid, ammonia, and ethanol.Type: GrantFiled: July 3, 2012Date of Patent: June 18, 2013Assignees: E I du Pont de Nemours and CompanyInventors: Perry G Caimi, Mark Emptage, Xu Li, Paul V Viitanen, Yat-Chen Chou, Mary Ann Franden, Min Zhang
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Patent number: 8372626Abstract: An L-arabinose utilizing yeast strain is provided for the production of ethanol by introducing and expressing bacterial araA, araB and araD genes. L-arabinose transporters are also introduced into the yeast to enhance the uptake of arabinose. The yeast carries additional genomic mutations enabling it to consume L-arabinose, even as the only carbon source, and to produce ethanol. A yeast strain engineered to metabolize arabinose through a novel pathway is also disclosed. Methods of producing ethanol include utilizing these modified yeast strains.Type: GrantFiled: October 21, 2010Date of Patent: February 12, 2013Assignee: Alliance for Sustainable Energy, LLCInventors: Min Zhang, Arjun Singh, Pirkko Suominen, Eric Knoshaug, Mary Ann Franden, Eric Jarvis
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Publication number: 20120276607Abstract: Strains of xylose utilizing Zymomonas with improved xylose utilization and ethanol production during fermentation in stress conditions were obtained using an adaptation method. The adaptation involved continuously growing xylose utilizing Zymomonas in media containing high sugars, acetic acid, ammonia, and ethanol.Type: ApplicationFiled: July 3, 2012Publication date: November 1, 2012Applicant: E. I. DU PONT DE NEMOURS AND COMPANY & ALLIANCE FOR SUSTAINABLE ENERGY LLCInventors: PERRY G. CAIMI, MARK EMPTAGE, XU LI, PAUL V. VIITANEN, YAT-CHEN CHOU, MARY ANN FRANDEN, MIN ZHANG
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Patent number: 8247208Abstract: Strains of xylose utilizing Zymomonas with improved xylose utilization and ethanol production during fermentation in stress conditions were obtained using an adaptation method. The adaptation involved continuously growing xylose utilizing Zymomonas in media containing high sugars, acetic acid, ammonia, and ethanol.Type: GrantFiled: December 18, 2009Date of Patent: August 21, 2012Assignees: E I du Pont de Nemours and CompanyInventors: Perry G. Caimi, Mark Emptage, Xu Li, Paul V. Viitanen, Yat-Chen Chou, Mary Ann Franden, Min Zhang
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Publication number: 20120129241Abstract: An L-arabinose utilizing yeast strain is provided for the production of ethanol by introducing and expressing bacterial araA, araB and araD genes. L-arabinose transporters are also introduced into the yeast to enhance the uptake of arabinose. The yeast carries additional genomic mutations enabling it to consume L-arabinose, even as the only carbon source, and to produce ethanol. A yeast strain engineered to metabolize arabinose through a novel pathway is also disclosed. Methods of producing ethanol include utilizing these modified yeast strains.Type: ApplicationFiled: October 21, 2010Publication date: May 24, 2012Applicant: ALLIANCE FOR SUSTAINABLE ENGERGY, LLCInventors: MIN ZHANG, ARJUN SINGH, PIRKKO SUOMINEN, ERIC KNOSHAUG, MARY ANN FRANDEN, ERIC JARVIS
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Patent number: 7998722Abstract: Strains of Zymomonas were engineered by introducing a chimeric xylose isomerase gene that contains a mutant promoter of the Z. mobilis glyceraldehyde-3-phosphate dehydrogenase gene. The promoter directs increased expression of xylose isomerase, and when the strain is in addition engineered for expression of xylulokinase, transaldolase and transketolase, improved utilization of xylose is obtained.Type: GrantFiled: March 25, 2009Date of Patent: August 16, 2011Assignees: E. I. du Pont de Nemours and Company, Alliance for Sustainable Energy LLCInventors: Paul V. Viitanen, Luan Tao, Yuying Zhang, Perry G. Caimi, Carol M. McCutchen, Laura McCole, Min Zhang, Yat-Chen Chou, Mary Ann Franden