Abstract: The invention provides a nucleic acid molecule comprising a gene encoding a fusion protein of a ligand and a protein having physiological activity, to be used for expressing the fusion protein in cells, tissue or the body. The invention further provides a nucleic acid molecule comprising the fusion protein-encoding gene, which is in the form of a plasmid, in a form encapsulated in a recombinant virus virion, or a form encapsulated in liposomes or lipid nanoparticles. The invention further relates to the use of a medicine which is a nucleic acid molecule comprising the fusion protein-encoding gene.

Abstract: Each of a plurality of servers includes a shared information storage region for storing information to be shared with other servers. The servers operate so as to match data of the shared information storage regions with each other. A first server manages a first local database. A second server generates query information for accessing the first local database, and stores the query information in the shared information storage region of the second server. The first server acquires the query information from the shared information storage region of the first server, and stores the result with respect to the query information in the shared information storage region of the first server. The second server acquires the result from the shared information storage region of the second server.

Abstract: An information processing system includes first and second computers and first and second bases. The first computer stores, as personal information of a user of a terminal, personal management information including an ID and contact detail of the user, generates personal time-series information with personal information and time added and generates processed time-series information by performing concealment on the personal information in the personal time-series information.

Abstract: Provided is an information linkage system, comprising: a processor; and a storage device coupled to the processor, the storage device holds identification information of a user and information on the user, which are added by a first organization, in association with each other, the processor: transmits to a second organization an information linkage application regarding information on any one item included in the information on the user; acquires, when the information linkage application is received, identification information of the user and information on the user of the item specified by the information linkage application, which are added by the second organization; and stores the acquired information in the storage device in association with the identification information of the user and the information on the user regarding the same user as a user identified by the acquired identification information, which are added by the first organization.

Abstract: Disclosed are a human serum albumin mutant that can be linked to a physiologically active protein to increase the stability of the protein in the blood, as well as a resulting protein produced by linking with the mutant. The protein produced by linking with the mutant consists of a human serum albumin mutant comprising the amino acid sequence set forth as SEQ ID NO:3 or an amino acid sequence that, in comparison with it, lacks not more than 10 amino acid residues and/or has not more than 10 amino acid residues replaced, with the proviso that the asparagine residue occurring at position 318 and the threonine at position 320 from the N-terminus of the amino acid sequence set forth as SEQ ID NO:3 are preserved and linked by peptide bonds via a single amino acid residue (X) except proline placed between those two amino acid residues, and a physiologically active protein linked to the mutant.

Abstract: It is provided an IoT system, comprising: a communication device in which an identification module for controlling a communication requirement is installed, and which is configured to communicate to/from a cloud server; an asset which is connected to the communication device; and a control server which is configured to manage setting of the communication between the communication device and the cloud server, wherein the control server is configured to: manage a relationship between the identification module and the communication device and a relationship between the communication device and the asset; and set the communication between the communication device and the cloud server in order to transfer information from the asset to the cloud server.

Abstract: Software that implements processing executed through coordination between multiple hubs is efficiently developed. An information processing system comprises a plurality of AP execution devices that are information processing apparatuses provided in each of a plurality of hubs to execute AP software. Each of the AP execution devices stores common AP software that executes the same processing blocks in the same order. The AP software includes transfer processing blocks implementing processing to coordinate processing of the processing blocks executed by a first one of the AP execution devices in a first one of the hubs with a second one of the AP execution devices in a second one of the hubs. Once the processing reaches a first one of the transfer processing blocks during sequential execution of the processing blocks of the AP software, the first AP execution device transmits a coordination start message notifying of start of the coordination, to the second AP execution device.

Abstract: Each of a plurality of servers includes a shared information storage region for storing information to be shared with other servers. The servers operate so as to match data of the shared information storage regions with each other. A first server manages a first local database. A second server generates query information for accessing the first local database, and stores the query information in the shared information storage region of the second server. The first server acquires the query information from the shared information storage region of the first server, and stores the result with respect to the query information in the shared information storage region of the first server. The second server acquires the result from the shared information storage region of the second server.

Abstract: Software that implements processing executed through coordination between multiple hubs is efficiently developed. An information processing system comprises a plurality of AP execution devices that are information processing apparatuses provided in each of a plurality of hubs to execute AP software. Each of the AP execution devices stores common AP software that executes the same processing blocks in the same order. The AP software includes transfer processing blocks implementing processing to coordinate processing of the processing blocks executed by a first one of the AP execution devices in a first one of the hubs with a second one of the AP execution devices in a second one of the hubs. Once the processing reaches a first one of the transfer processing blocks during sequential execution of the processing blocks of the AP software, the first AP execution device transmits a coordination start message notifying of start of the coordination, to the second AP execution device.

Abstract: Disclosed are a human serum albumin mutant that can be linked to a physiologically active protein to increase the stability of the protein in the blood, as well as a resulting protein produced by linking with the mutant. The protein produced by linking with the mutant consists of a human serum albumin mutant comprising the amino acid sequence set forth as SEQ ID NO:3 or an amino acid sequence that, in comparison with it, lacks not more than 10 amino acid residues and/or has not more than 10 amino acid residues replaced, with the proviso that the asparagine residue occurring at position 318 and the threonine at position 320 from the N-terminus of the amino acid sequence set forth as SEQ ID NO:3 are preserved and linked by peptide bonds via a single amino acid residue (X) except proline placed between those two amino acid residues, and a physiologically active protein linked to the mutant.

Abstract: Disclosed are a human serum albumin mutant that can be linked to a physiologically active protein to increase the stability of the protein in the blood, as well as a resulting protein produced by linking with the mutant. The protein produced by linking with the mutant consists of a human serum albumin mutant comprising the amino acid sequence set forth as SEQ ID NO:3 or an amino acid sequence that, in comparison with it, lacks not more than 10 amino acid residues and/or has not more than 10 amino acid residues replaced, with the proviso that the asparagine residue occurring at position 318 and the threonine at position 320 from the N-terminus of the amino acid sequence set forth as SEQ ID NO:3 are preserved and linked by peptide bonds via a single amino acid residue (X) except proline placed between those two amino acid residues, and a physiologically active protein linked to the mutant.

Abstract: A distributed processing system includes a plurality of information processing apparatuses communicably coupled to one another and is capable of performing parallel processing in which the information processing apparatus performs predetermined processing in parallel with the other information processing apparatuses.

Abstract: The design and development of a data analysis process is assisted and the burden on the user such as a data analyst in data analysis process is reduced.

Abstract: Disclosed are a human serum albumin mutant that can be linked to a physiologically active protein to increase the stability of the protein in the blood, as well as a resulting protein produced by linking with the mutant. The protein produced by linking with the mutant consists of a human serum albumin mutant comprising the amino acid sequence set forth as SEQ ID NO:3 or an amino acid sequence that, in comparison with it, lacks not more than 10 amino acid residues and/or has not more than 10 amino acid residues replaced, with the proviso that the asparagine residue occurring at position 318 and the threonine at position 320 from the N-terminus of the amino acid sequence set forth as SEQ ID NO:3 are preserved and linked by peptide bonds via a single amino acid residue (X) except proline placed between those two amino acid residues, and a physiologically active protein linked to the mutant.

Abstract: Provided is an information linkage system, comprising: a processor; and a storage device coupled to the processor, the storage device holds identification information of a user and information on the user, which are added by a first organization, in association with each other, the processor: transmits to a second organization an information linkage application regarding information on any one item included in the information on the user; acquires, when the information linkage application is received, identification information of the user and information on the user of the item specified by the information linkage application, which are added by the second organization; and stores the acquired information in the storage device in association with the identification information of the user and the information on the user regarding the same user as a user identified by the acquired identification information, which are added by the first organization.

Abstract: Disclosed are a human serum albumin mutant that can be linked to a physiologically active protein to increase the stability of the protein in the blood, as well as a resulting protein produced by linking with the mutant. The protein produced by linking with the mutant consists of a human serum albumin mutant comprising the amino acid sequence set forth as SEQ ID NO:3 or an amino acid sequence that, in comparison with it, lacks not more than 10 amino acid residues and/or has not more than 10 amino acid residues replaced, with the proviso that the asparagine residue occurring at position 318 and the threonine at position 320 from the N-terminus of the amino acid sequence set forth as SEQ ID NO:3 are preserved and linked by peptide bonds via a single amino acid residue (X) except proline placed between those two amino acid residues, and a physiologically active protein linked to the mutant.

Abstract: A distributed processing system includes a plurality of information processing apparatuses communicably coupled to one another and is capable of performing parallel processing in which the information processing apparatus performs predetermined processing in parallel with the other information processing apparatuses.

Abstract: The design and development of a data analysis process is assisted and the burden on the user such as a data analyst in data analysis process is reduced.

Abstract: A data processing system comprises: at least one each of a plurality of types of data processing module conducting different types of the data processing; data flows through which a series of different types of data processing is conducted on a message and a message subjected to the series of different types of data processing is sent to the destination; and a dispatcher distributes the message and a message subjected to the data processing by the data processing module to a subsequent data processing module, wherein the dispatcher conducts: detecting a specific data processing module in a specific status of being a bottleneck; determining the number of the specific data processing module to resolve the specific status by increasing the number of the specific data processing module; and setting the number of the specific data processing module to the number to resolve the specific status.

Abstract: The present invention relates to a distributed processing system having a master node and a plurality of worker nodes. Each worker node has an assigned identifier. A worker node caches in its own memory first output data, which is the result of the execution of a first task, and copies said first output data to another worker node. The master node selects, on the basis of the identifier information of the first worker node, a worker node to which to assign a second task, wherein the first output data is used as input data.