Abstract: A method is provided herein, the method includes: applying a sample comprising target nucleic acids to a sample application zone of a substrate; and flowing a nucleic acid amplification reaction mixture across a length of the substrate through the sample application zone to amplify the target nucleic acid forming a nucleic acid amplification product; wherein the target nucleic acid having a first molecular weight is substantially immobilized at the sample application zone and wherein the amplification product having a second molecular weight migrates away from the sample application zone. An associated device is also provided.

Abstract: A membrane including a block copolymer is presented. The block copolymer includes at least one block A including structural units having a formula (I), and at least one block B including structural units having a formula (II). A hollow-fiber membrane for hemodialysis or hemofiltration, and associated block copolymer are also presented.

Abstract: A porous membrane patterning technique is provided. In one embodiment, a porous membrane may be patterned via printing on the porous membrane with a solvent such that the porous membrane collapses where the solvent is applied. In another embodiment, a patterned porous membrane may be formed by casting a solution including at least components of the porous membrane into voids of a casting plate or stencil, removing the casting plate, and letting the remaining components go through a phase inversion process to form porous membrane regions.

Abstract: A membrane including a polyarylnitrile copolymer is presented. The polyarylnitrile copolymer includes structural units having a formula (I) and at least one terminal group having a formula (II): wherein “a” is 0, 1, 2, or 3; “m” is an integer having a value of 35 to 150; R1 is independently at each occurrence a hyrogen atom, a halogen atom, a nitro group, a cyano group, a C1-C12 aliphatic radical, a C3-C12 cycloaliphatic radical, or a C3-C12 aromatic radical; R2 and R3 are independently a C1-C12 aliphatic radical, a C3-C12 cycloaliphatic radical, or a C3-C12 aromatic radical; L is an oxygen atom or a sulfur atom; and Ar is independently at each occurrence a residue of an aromatic diol or a residue of an aromatic dihalide.

Abstract: A colorimetric time indicator configured to indicate time specificity is provided. The colorimetric time indicator includes a colorimetric layer configured to be operatively coupled to a disposable medical device. The colorimetric time indicator is configured to indicate the time specificity via one or more visual indicators upon exposure to one or more external stimuli.

Abstract: A separation matrix comprises a porous surface layer; and a bulk porous support, wherein both the porous surface layer and the bulk porous support comprising a block copolymer. The block copolymer comprises A-B or A-B-A repeating units, wherein A and B at each occurrence are two different blocks of oligomer, or polymer. A structural unit of block A is derived from one or more atom transfer radical polymerization (ATRP)-active monomer or oligomer and a structural unit of block B is derived from a thermoplastic ATRP-active macro initiator. A poly dispersity index of the block copolymer is at least about 2.

Abstract: An optical data storage medium is provided. The optical data storage medium includes a polymer matrix; a reactant capable of undergoing a change upon triplet excitation, thereby causing a refractive index change; and a non-linear sensitizer capable of absorbing actinic radiation to cause upper triplet energy transfer to said reactant. The refractive index change capacity of the medium is at least about 0.005. The non-linear sensitizer comprises a triarylmethane dye.

Abstract: An optical article comprising a first file encoded on the optical article comprising data structure information; a second file encoded on the optical article comprising a backup of the first file; wherein at least one of the first file or the second file must be fully readable for the player to read the data on the optical article; and a mark disposed on at least a portion of the optical article where the first file is encoded and at least a portion of the optical article where the second file is encoded; wherein the mark comprises an optical state change material; wherein the optical state change material undergoes a change in its optical state when exposed to an activation signal selected from one or more of a laser, thermal energy, infrared rays, X-rays, gamma rays, microwaves, visible light, ultraviolet light, ultrasound waves, radio frequency waves, electrical energy, chemical energy, magnetic energy, and mechanical energy; wherein the optical article is transformed from a pre-activated state to an activ

Abstract: In accordance with one aspect of the present invention, a method for recording holographic data in an optical data storage medium is provided. The method includes (i) providing an optical data storage medium including: (a) a thermoplastic polymer matrix, (b) a latent acid generator, (c) a non-linear sensitizer, and (d) a reactant including a latent chromophore. The method further includes (ii) irradiating a volume element of the optical data storage medium with an interference pattern, said interference pattern including an incident radiation having a wavelength and an intensity sufficient to cause upper triplet energy transfer from the non-linear sensitizer to the latent acid generator, thereby generating an acid, wherein the latent acid generator is substantially non-responsive to said incident radiation.

Abstract: An optical article comprising a plurality of optically detectable marks disposed on a surface of the optical article; a removable electrical device disposed on the surface of the optical article; wherein the electrical device is operatively coupled to the optical article; and wherein the electrical device is configured to interact with an activation signal when brought in direct contact with a communication device that applies the activation signal to the electrical device. A removable electrical device is also provided. A system and a method for activation are also provided.

Abstract: An equipment comprising a receptacle for receiving an optical article; a first set of electrical connectors configured to be in direct contact with a second set of electrical connectors disposed on the optical article, when the optical article is received by the receptacle; an activation device operably coupled with the first set of electrical connectors; wherein the activation device is configured to generate an activation signal which is transmitted to the second set of electrical connectors by the first set of electrical connectors, wherein an electrical device is configured to provide a power component to the optical article via the first set of electrical connectors and the second set of electrical connectors which are in direct contact. A system comprising the equipment is also provided. Also provided is a checkout device.

Abstract: An optical article comprising a primary mark disposed on the optical article and a secondary mark disposed on the optical article in close proximity to the primary mark. The primary mark comprises a first optical-state change material and the secondary mark comprises a second optical-state change material. The optical article is transformed from a pre-activated state to an activated state when a localized authorized activation method is used that selectively activates the primary mark. The optical article is transformed from a pre-activated state to an deactivated state when a non-localized unauthorized activation method is used that activates the secondary mark along with the primary mark resulting in the second optical-state change material undergoing a reverse color change when compared to the first optical-state change material. An optical article with a single mark including multiple color change optical-state change material is also disclosed.

Abstract: The present disclosure relates to optical media and the formation and use of such media. In certain embodiments the optical media or a composition suitable for such media includes a polymeric matrix or substrate. A dye, such as an energy transfer dye is chemically appended to the polymeric matrix or substrate, such as by one or more covalent bonds.

Abstract: In accordance with one aspect of the present invention, a method for recording holographic data in an optical data storage medium is provided. The method includes (i) providing an optical data storage medium including: (a) a thermoplastic polymer matrix, (b) a latent acid generator, (c) a non-linear sensitizer, and (d) a reactant including a latent chromophore. The method further includes (ii) irradiating a volume element of the optical data storage medium with an interference pattern, said interference pattern including an incident radiation having a wavelength and an intensity sufficient to cause upper triplet energy transfer from the non-linear sensitizer to the latent acid generator, thereby generating an acid, wherein the latent acid generator is substantially non-responsive to said incident radiation.

Abstract: An activation system for optical media in one embodiment includes a tag having at least one pair of conductors with at least one heating element coupled to the conductors. The heating element is oriented proximate one or more activation regions on the optical media, and wherein the heating element activates the optical media. The tag in one embodiment is an elongate flexible tag material with a number of conductors that couple on one end to heating elements wherein the heating elements are disposed within a media case such that they are proximate activation regions on a media article.

Abstract: A method of changing a functionality of an optical article is provided. The method includes exposing the optical article to an external stimulus. The optical article includes an electrically responsive layer being configured to transform from a first optical state to a second optical state upon exposure to the external stimulus. The electrically responsive layer is configured to transform from a first optical state to a second optical state upon exposure to an external stimulus, and is capable of irreversibly transforming the optical article from the pre-activated state of functionality to the activated state of functionality.

Abstract: An optical data storage medium is provided. The optical data storage medium includes a polymer matrix; a reactant capable of undergoing a change upon triplet excitation, thereby causing a refractive index change; and a non-linear sensitizer capable of absorbing actinic radiation to cause upper triplet energy transfer to said reactant. The refractive index change capacity of the medium is at least about 0.005. The non-linear sensitizer comprises a triarylmethane dye.

Abstract: An optical data storage medium is provided. The optical data storage medium includes a polymer matrix; a reactant capable of undergoing a change upon triplet excitation, thereby causing a refractive index change; and a non-linear sensitizer capable of absorbing actinic radiation to cause upper triplet energy transfer to said reactant. The refractive index change capacity of the medium is at least about 0.1. The reactant comprises polyvinyl chlorocinnamate, polyvinyl methoxycinnamate, or a combination thereof.

Abstract: The present disclosure relates to optical media and the formation and use of such media. In certain embodiments the optical media or a composition suitable for such media includes a polymeric matrix or substrate. A dye, such as an energy transfer dye is chemically appended to the polymeric matrix or substrate, such as by one or more covalent bonds.

Abstract: An optical article comprising a mark disposed on the optical article; wherein the mark comprises an optical state change material; wherein the optical state change material undergoes a change in its optical state when exposed to an activation signal selected from one or more of a laser, thermal energy, infrared rays, X-rays, gamma rays, microwaves, visible light, ultraviolet light, ultrasound waves, radio frequency waves, electrical energy, chemical energy, magnetic energy, and mechanical energy; wherein the optical article is transformed from a pre-activated state to an activated state when an authorized activation method is used; and wherein the optical article is transformed from a pre-activated state to an incorrectly activated state when an unauthorized activation method is used. A method and a system for changing the functionality of the optical article are also provided.