Patents by Inventor Mechthild Rieping

Mechthild Rieping has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20030017554
    Abstract: A process for the fermentative preparation of an L-amino acid which entails the steps of:
    Type: Application
    Filed: February 19, 2002
    Publication date: January 23, 2003
    Inventors: Mechthild Rieping, Georg Thierbach
  • Publication number: 20020173010
    Abstract: D-pantothenic acid and/or a salt thereof or feedstuffs additives comprising these are prepared by fermentation of a microorganism of the Enterobacteriaceae family, in particular one which already produces D-pantothenic acid, wherein the nucleotide sequence(s) in the microorganism which code(s) for the poxB gene is (are) attenuated, in particular eliminated.
    Type: Application
    Filed: March 14, 2002
    Publication date: November 21, 2002
    Applicant: DEGUSSA AG
    Inventor: Mechthild Rieping
  • Publication number: 20020155551
    Abstract: Process for the fermentative preparation of L-threonine The invention provides a process for the fermentative preparation of L-threonine using Enterobacteriaceae which in particular already produce L-threonine and in which the nucleotide sequence(s) of coryneform bacteria which code(s) for the thrE gene are enhanced, in particular over-expressed.
    Type: Application
    Filed: April 16, 2001
    Publication date: October 24, 2002
    Applicant: DEGUSSA AG
    Inventor: Mechthild Rieping
  • Publication number: 20020151700
    Abstract: The present invention provides arrays of single- or doublestranded desoxyribonucleic acid (DNA) probes immobilized on solid supports and for using those probe arrays to detect specific nucleic acid sequences contained in a target nucleic acid in a sample, especially a method to monitore a fermentation process.
    Type: Application
    Filed: July 17, 2001
    Publication date: October 17, 2002
    Inventors: Mike Farwick, Jennifer Brehme, Thomas Hermann, Brigitte Bathe, Achim Marx, Bettina Mockel, Mechthild Rieping, Eugen Ermantraut, Thomas Ellinger, Klaus Huthmacher, Walter Pfefferle
  • Publication number: 20020137149
    Abstract: A method for the fermentative preparation of D-pantothenic acid and/or its salts or feedstuffs additives containing these by the fermentation of microorganisms from the Enterobacteriaceae family in particular those which already produce D-pantothenic acid, wherein the nucleotide sequence(s) coding for the glyA gene is enhanced in the microorganisms, in particular is overexpressed.
    Type: Application
    Filed: January 23, 2002
    Publication date: September 26, 2002
    Applicant: DEGUSSA AG
    Inventors: Thomas Hermann, Achim Marx, Walter Pfefferle, Mechthild Rieping
  • Publication number: 20020137148
    Abstract: A process for the enzymatic production of D-pantothenic acid and/or its salts or feedstuffs additives containing the latter by fermentation of microorganisms of the family Enterobacteriaceae, in particular those that already produce D-pantothenic acid, wherein the nucleotide sequence(s) coding for the serC gene is/are enhanced, in particular overexpressed, in the microorganisms.
    Type: Application
    Filed: January 23, 2002
    Publication date: September 26, 2002
    Applicant: DEGUSSA AG
    Inventors: Mechthild Rieping, Thomas Hermann, Walter Pfefferle
  • Publication number: 20020127678
    Abstract: The invention provides a process for the fermentative preparation of L-threonine using Enterobacteriaceae which in particular already produce L-threonine and in which the nucleotide sequence(s) which code(s) for the mqo gene are enhanced, in particular over-expressed.
    Type: Application
    Filed: March 8, 2001
    Publication date: September 12, 2002
    Inventors: Mechthild Rieping, Georg Thierbach, Michel Eduard Van Der Rest, Douwe Molenaar
  • Publication number: 20020106760
    Abstract: The invention relates to an isolated polynucleotide having a polynucleotide sequence which codes for the dps gene, and a host-vector system having a coryneform host bacterium in which the dps gene is present in attenuated form and a vector which carries at least the dps gene according to SEQ ID No 1, and the use of polynucleotides which comprise the sequences according to the invention as hybridization probes.
    Type: Application
    Filed: September 19, 2001
    Publication date: August 8, 2002
    Inventors: Brigitte Bathe, Caroline Kreutzer, Mechthild Rieping, Achim Marx, Mike Farwick, Walter Pfefferle
  • Publication number: 20020107377
    Abstract: The invention relates to an isolated polynucleotide having a polynucleotide sequence which codes for the ftsX gene, and a host-vector system having a coryneform host bacterium in which the ftsX gene is present in attenuated form and a vector which carries at least the ftsX gene according to SEQ ID No 1, and the use of polynucleotides which comprise the sequences according to the invention as hybridization probes.
    Type: Application
    Filed: September 6, 2001
    Publication date: August 8, 2002
    Inventors: Mike Farwick, Klaus Huthmacher, Walter Pfefferle, Jennifer Brehme, Mechthild Rieping
  • Publication number: 20020106756
    Abstract: The invention relates to an isolated polynucleotide having a polynucleotide sequence which codes for the sigh gene, and a host-vector system having a coryneform host bacterium in which the sigh gene is present in attenuated form and a vector which carries at least the sigh gene according to SEQ ID No 1, and the use of polynucleotides which comprise the sequences according to the invention as hybridization probes.
    Type: Application
    Filed: August 31, 2001
    Publication date: August 8, 2002
    Inventors: Brigitte Bathe, Indra Schroder, Mechthild Rieping, Achim Marx, Mike Farwick, Walter Pfefferle, Thomas Hermann
  • Publication number: 20020102669
    Abstract: The invention relates to an isolated polynucleotide having a polynucleotide sequence which codes for the clpC gene, and a host-vector system having a coryneform host bacterium in which the clpC gene is present in attenuated form and a vector which carries at least the clpC gene according to SEQ ID No 1, and the use of polynucleotides which comprise the sequences according to the invention as hybridization probes.
    Type: Application
    Filed: September 10, 2001
    Publication date: August 1, 2002
    Inventors: Mike Farwick, Klaus Huthmacher, Brigitte Bathe, Walter Pfefferle, Mechthild Rieping
  • Publication number: 20020098554
    Abstract: The invention relates to an isolated polynucleotide containing a polynucleotide sequence selected from the group
    Type: Application
    Filed: March 13, 2001
    Publication date: July 25, 2002
    Inventors: Mike Farwick, Klaus Huthmacher, Brigitte Bathe, Mechthild Rieping, Walter Pfefferle
  • Publication number: 20020086371
    Abstract: The invention relates to L-lysine-producing strains of corynebacteria with enhanced lysE gene (lysine export carrier gene), in which strains additional genes chosen from the group comprising the dapA gene (dihydrodipicolinate synthase gene), the lysC gene (aspartate kinase gene), the dapB gene (dihydrodipicolinate reductase gene) and the pyc gene, but especially the dapA gene and the lysC gene (aspartate kinase gene), are enhanced and, in particular, over-expressed, and to a process for the preparation of L-lysine.
    Type: Application
    Filed: March 8, 2001
    Publication date: July 4, 2002
    Applicant: Degussa-Huls Aktiengesellschaft
    Inventors: Caroline Kreutzer, Stephan Hans, Mechthild Rieping, Bettina Mockel, Walter Pfefferle, Lothar Eggeling, Hermann Sahm, Miroslav Patek
  • Publication number: 20020055151
    Abstract: The invention relates to a process for the fermentative preparation of L-threonine in which an L-threonine-producing microorganism of the Enterobacteriaceae family is cultured by the feed process, and a portion of the fermentation broth is then separated off in order to be utilized for inoculation of further media.
    Type: Application
    Filed: August 24, 2001
    Publication date: May 9, 2002
    Inventors: Thomas Hermann, Mechthild Rieping
  • Patent number: 6200785
    Abstract: The invention relates to L-lysine-producing strains of corynebacteria with amplified lysE gene (lysine export carrier gene), in which strains additional genes chosen from the group comprising the dapA gene (dihydrodipicolinate synthase gene), the lysC gene (aspartate kinase gene), the dapB gene (dihydrodipicolinate reductase gene) and the pyc gene, but especially the dapA gene and the lysC gene (aspartate kinase gene), are amplified and, in particular, overexpressed, and to a process for the preparation of L-lysine.
    Type: Grant
    Filed: July 14, 1999
    Date of Patent: March 13, 2001
    Assignee: Degussa-Huls Aktiengesellschaft
    Inventors: Caroline Kreutzer, Stephan Hans, Mechthild Rieping, Bettina Mockel, Walter Pfeffere, Lothar Eggeling, Hermann Sahm, Miroslav Patek
  • Patent number: 6184006
    Abstract: A method for the production of D-pantothenic acid by the fermentation of microorganisms of the family Enterobacteriacae producing D-pantothenic acid which is characterized in that strains are used which a) Contain the plasmid pFV31 and/or pFV202 and that b) A panD gene and optionally other nucleotide sequences coding for aspartate-1-decarboxylase are enhanced, especially overexpressed in these microorganisms, c) The pantothenic acid is enriched in the medium or in the cells of the microorganisms and d) The pantothenic acid formed is isolated.
    Type: Grant
    Filed: May 26, 1999
    Date of Patent: February 6, 2001
    Assignee: Degussa-Hüls Aktiengesellschaft
    Inventors: Mechthild Rieping, Georg Thierbach, Walter Pfefferle, Nicole Dusch, Jorn Kalinowski, Alfred Puhler