Abstract: An object processing system within a trailer for a tracker trailer is discloses. The object processing system includes an input area of the trailer at which objects to be processed may be presented, a perception system for providing perception data regarding objects to be processed, and a primary transport system for providing transport of each object in one of at least two primary transport directions within the trailer based on the perception data.

Abstract: An online concierge system iteratively makes a batch of one or more orders available to an increasing number of shoppers to choose to fulfill. Each shopper may choose to accept or reject a batch for fulfillment. To improve batch acceptance and matching between batches and shoppers, the batches are scored with respect to expected resource costs, likelihood of acceptance by the shopper, and/or other quality metrics to iteratively offer the batch to an increasing number of shoppers (prioritizing the scoring factors) until a shopper accepts. The number of shoppers notified of the batch and the frequency that additional shoppers are selected may vary based on characteristics of the batch and likelihood the batch will be accepted by a shopper.

Abstract: A storage, retrieval and processing system for processing objects is disclosed. The storage, retrieval and processing system includes a plurality of storage bins providing storage of a plurality of objects, where the plurality of storage bins is in communication with a retrieval conveyance system, a programmable motion device in communication with the retrieval conveyance system for receiving the storage bins from the plurality of bins, where the programmable motion device includes an end effector for grasping and moving a selected object out of a selected storage bin, and a movable carriage for receiving the selected object from the end effector of the programmable motion device, and for carrying the selected object to one of a plurality of destination bins.

Abstract: Methods and apparatus, including computer program products, are provided for remote monitoring. In some example implementations, there is provided a method. The method may include receiving, at a remote monitor, a notification message representative of an event detected, by a server, from analyte sensor data obtained from a receiver monitoring an analyte state of a host; presenting, at the remote monitor, the notification message to activate the remote monitor, wherein the remote monitor is configured by the server to receive the notification message to augment the receiver monitoring of the analyte state of the host; accessing, by the remote monitor, the server, in response to the presenting of the notification message; and receiving, in response to the accessing, information including at least the analyte sensor data. Related systems, methods, and articles of manufacture are also disclosed.

Abstract: The present invention is directed to anti-PVRIG antibodies and stable liquid pharmaceutical formulations thereof. The present invention is directed to monotherapy and combination treatments with anti-PVRIG antibodies and anti-PD-1 antibodies, in particular nivolumab, using stable liquid pharmaceutical formulations thereof.

Abstract: Systems comprising a folded camera that includes a lens module with a native aperture, the lens module having a height HM, an adaptive aperture located between the native aperture and an optical path folding element, and an adaptive aperture forming mechanism for forming the adaptive aperture, wherein the adaptive aperture forming mechanism has a height HAA not larger than HM, and methods of using same. In various embodiments, the adaptive aperture forming mechanism includes an actuator and at least one pair of blades operative to be moved by the actuator to a plurality of positions to form the adaptive aperture.

Abstract: A therapeutic device comprises an upper massage surface having a generally central spinous channel, a first domed portion on a first lateral side of the central spinous channel and a second domed portion on a second lateral side of the central spinous channel. The device has a lower base surface, a front edge, and a rear edge, with the upper massage surface extending between front edge and the rear edge. The device further has a first lateral edge on one side of the therapeutic device and a second lateral edge on an opposing side of the therapeutic device, such that the distance between the first and second lateral edges is greater than the distance between the front edge and the rear edge.

Abstract: A zoom camera comprising an optical path folding element (OPFE) for folding the light from a first optical path to a second optical path, a first lens having a first optical axis and a first effective focal length EFLL1, the first optical axis being along the second optical path, a collimating lens having a second optical axis, and an image sensor located on the second optical path, wherein the collimating lens is movable between at least a first state and a second state, wherein in the first state the collimating lens is positioned in the second optical path between the OPFE and the first lens such that light entering the first lens arrives only from the image side of the collimating lens, and wherein in the second state the collimating lens is positioned outside the first optical path such that light entering the first lens does not arrive from the image side of the collimating lens.

Abstract: This invention provides mechanical valve device and ring systems for cardiac valve replacement, wherein the mechanical valve devices comprises two or more leaflets, each leaflet comprising at least a first material which reduces electrostatic forces between blood and device components, reduces adhesion between blood and device components or a combination thereof; and optionally further comprises at least a first magnet incorporated within at least one of the leaflets; and a valve constraining ring, comprising at least a first material which reduces electrostatic forces between blood and device components, reduces adhesion between blood and device components or a combination thereof; and internally located attachment regions for the leaflets; and optionally at least a second magnet of matched polarity to said first magnet, incorporated within the valve constraining ring at regions proximal to said first magnet within said leaflet such that repulsive forces are present when said first magnet and said second mag

Abstract: Folded digital cameras comprising a lens system with a lens and an image sensor, the lens having N?6 lens elements Li, an effective focal length (EFL) and a total track length (TTL), wherein each lens element has a respective focal length fi and wherein a first lens element L1 faces an object side, and an optical path folding element (OPFE) for providing a folded optical path between an object and the lens. In some embodiments, the lens system has a focusing range that covers object-lens distances from infinity to a minimal object distance (MIOD), wherein MIOD/EFL is smaller than 20 or even 7. In some embodiments, the ratio of a maximal chief ray angle to a field of view of the folded camera Max CRA/FOV is smaller than 0.25 or even 0.15 when the camera is focused at infinity.

Abstract: Aspects of the disclosures allow for a touchless or hands-free closing, opening, and holding (in a closed state) of a door system, including, but not limited to doors for stalls in public restrooms. Embodiments of the door opening system may include touchless mechanisms and methods that utilize various mechanical, electromechanical, and/or electronic systems and components. Aspects of the disclosures also allow for occupancy indication for a door system, including, but not limited to doors for stalls in public restrooms. Embodiments of the occupancy indication system may include an occupancy indicator that may be pushed away from a door panel to indicate whether the bathroom stall is occupied or not occupied.

Abstract: The present invention concerns novel compounds, pharmaceutical compositions, and methods for promoting nerve regeneration, particularly including sympathetic nerve regeneration in the heart following a myocardial infarction and damage to the central nervous system, such as after a cerebrovascular accident, through inhibitory extracellular matrix that includes chondroitin sulfate roteoglycans (CSPG).

Abstract: A method for fusion of radar and visual information, the method comprises: obtaining visual information and radar information about a three dimensional (3D) space located within a field of view of a camera that acquired the visual information and within a field of view of a radar that acquired the radar information; finding, based on the visual information, estimated visual-detection-based (VDB) objects and estimated VDB locations of the estimated VDB objects within the 3D space; wherein the estimated VDB locations exhibit a distance ambiguity; determining hybrid-detection-based (HDB) objects and HDB locations of the HDB objects, based on (i) the radar information, (ii) the estimated VDB objects, and (iii) the estimated VDB locations of the VDB objects.

Abstract: Provided herein are novel compounds, compositions, that can used as clickable, photo-affinity labeling (PAL) probes methods for use in screening NAD+ binding proteins.

Abstract: A portable air processing system that takes air from the ambient or other component, heats the air to a sufficient temperature so as to deactivate at least one type of pathogen or allergen, then cools the air to a comfortable breathing temperature, and then feeds this processed air under positive pressure to a controlled environment or mask covering the nose and mouth of a wearer, thus enabling one to breath cleaner air from a controlled source while mobile or stationary.

Abstract: A computer-implemented method comprising: receiving, by a computing device, prescription information for an individual identifying a medication and a condition; identifying, by the computing device, job roles impacted by the condition; identifying, by the computing device, job roles impacted by side effects of the medication; determining, by the computing device, that a working capacity of the individual is diminished by the condition or the side effects of the medication based on job roles of the individual; generating, by the computing device, mitigation instructions in response to the determining; and executing, by the computing device, the mitigation instructions.

Abstract: Mutant mono ADP-ribose-polymerases (mono-PARP) proteins and small molecule compound substrates specific for the mutant mono-PARP proteins as well as methods of using these compositions to identify protein targets of the mono-PARPs and to screen for antagonists of the mono-PARPs are described.

Abstract: Systems and method are provided for securing physical-location transfers that include receiving object information associated with a particular physical location; receiving user information associated with a user that owns the physical location; generating a protected object associated with the physical location, wherein the protected object is generated based on the object information and the user information; generating a user key associated with the physical location, wherein generating the user key is based on the object information and the user information; storing the user key and a physical-location identifier associated with the physical location in a database; receiving a transfer request associated with the physical location, the transfer request including the user key; transmitting an authorization request for the transfer associated with the physical location; and receiving one of an authorization for the transfer associated with the physical location and a cancellation for the transfer associated

Abstract: The present invention provides compounds useful as mitochondrial permeability transition pore (mtPTP) inhibitors, the compounds being of Formula (I), or a pharmaceutically acceptable salt thereof wherein R1 is selected from the group of H, halogen, and C1-C3 alkyl; and R2 is selected from the group of H, CF3, and halogen; with the proviso that at least one of R1 and R2 is halogen or CF3.