Patents by Inventor Michael Block

Michael Block has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170126336
    Abstract: The invention is related to a smart testing apparatus and preferably a method for testing at least a first DUT and a second DUT using a mobile communications testing device. The method comprises the steps of determining, whether a first RF test signal from/to the first DUT interferes with a second RF test signal from/to the second DUT. It determines, whether the second RF test signal from/to second DUT interferes with the first RF test signal from/to the first DUT. It predetermines, whether at least measuring the first measuring result obtained by applying the first RF test signal is disturbed above a first disturbance threshold value. It predetermines, whether at least a second measuring result obtained by applying the second RF test signal is disturbed above a second disturbance threshold value.
    Type: Application
    Filed: May 20, 2016
    Publication date: May 4, 2017
    Inventors: Anton STROHMEIER, Michael BLOCK, Ralf PLAUMANN, Thomas LUTZ, Franz OBERMAYR, Christiane KLAUS, Jens VOLKMANN
  • Patent number: 9573911
    Abstract: The present invention provides compounds of Formulae (I)-(V), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. In one aspect, compounds of the present invention are useful as glycosyltransferase inhibitors, in particular, O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) inhibitors. In another aspect, compounds of the present invention are useful as kinase inhibitors, in particular, PLK1 inhibitors, GSK3P inhibitors, or MAPKAPK2 inhibitors. The present invention further provides methods of using the inventive compounds, e.g., as biological probes to study the inhibition of OGT and/or kinase activity and as therapeutics, e.g., for the treatment of OGT-associated and/or kinase-associated conditions.
    Type: Grant
    Filed: July 6, 2012
    Date of Patent: February 21, 2017
    Assignee: President and Fellows of Harvard College
    Inventors: Suzanne Walker Kahne, Jiaoyang Jiang, Michael Block Lazarus
  • Publication number: 20160263662
    Abstract: A drill bit jig includes an elongate member, two jig securing elements and a drill bit guide. The drill bit guide includes a plurality of through holes where the axes of the through holes are parallel to the axis of the elongate member. Each of the plurality of through holes in the drill bit guide has a different diameter for accommodating drill bits of different thicknesses. The jig securing elements each include an L-shaped bolt and a door protecting material encasing one of the straight sections of the bolt. The drill bit jig also includes a core check to determine if a hole being drilled along the width of the door is straight.
    Type: Application
    Filed: May 23, 2016
    Publication date: September 15, 2016
    Inventor: Michael Block
  • Patent number: 9346107
    Abstract: A drill bit jig includes an elongate member, two jig securing elements and a drill bit guide. The drill bit guide includes a plurality of through holes where the axes of the through holes are parallel to the axis of the elongate member. Each of the plurality of through holes in the drill bit guide has a different diameter for accommodating drill bits of different thicknesses. The jig securing elements each include an L-shaped bolt and a door protecting material encasing one of the straight sections of the bolt. The drill bit jig also includes a core check to determine if a hole being drilled along the width of the door is straight.
    Type: Grant
    Filed: March 8, 2012
    Date of Patent: May 24, 2016
    Inventor: Michael Block
  • Publication number: 20160036545
    Abstract: A measuring system comprises a timing unit and at least two signal generators. The signal generators are each configured to generate a measuring signal and to supply it to a device under test. The timing unit is configured to generate start time signals, which each indicate an allowed start time of the measuring signals. Said signal generators are configured to only start generating the measuring signals at least instances of start time signals.
    Type: Application
    Filed: July 31, 2015
    Publication date: February 4, 2016
    Inventors: Ralf Plaumann, Feng Xie, Thomas Lutz, Michael Block, Hailiang Jin
  • Patent number: 8957075
    Abstract: The present invention provides inhibitors of O-GIcNAc transferase. Typically, the inhibitors are quinolinone-6-sulfonamides. The invention also provides pharmaceutical compositions thereof and methods for using the same in diabetes and complications thereof, neurodegenerative diseases, cancers, autoimmune diseases, and inflammatory diseases.
    Type: Grant
    Filed: June 1, 2010
    Date of Patent: February 17, 2015
    Assignee: President and Fellows of Harvard College
    Inventors: Suzanne Walker Kahne, Michael Block Lazarus, Benjamin J. Gross
  • Patent number: 8757939
    Abstract: A drill bit jig includes an elongate member, two jig securing elements and a rotatable drill bit guide. The elongate member is hollow so that one or more elongate drill bits may be stored therein. The drill bit guide includes a plurality of through holes where the axes of the through holes are parallel to the axis of the elongate member. Each of the plurality of through holes in the drill bit guide has a different diameter for accommodating drill bits of different thicknesses. The jig securing elements each include an L-shaped bolt and a door protecting material encasing one of the straight sections of the bolt.
    Type: Grant
    Filed: December 31, 2009
    Date of Patent: June 24, 2014
    Inventor: Michael Block
  • Publication number: 20140163079
    Abstract: The present invention provides compounds of Formulae (I)-(V), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. In one aspect, compounds of the present invention are useful as glycosyltransferase inhibitors, in particular, O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) inhibitors. In another aspect, compounds of the present invention are useful as kinase inhibitors, in particular, PLK1 inhibitors, GSK3P inhibitors, or MAPKAPK2 inhibitors. The present invention further provides methods of using the inventive compounds, e.g., as biological probes to study the inhibition of OGT and/or kinase activity and as therapeutics, e.g., for the treatment of OGT-associated and/or kinase-associated conditions.
    Type: Application
    Filed: July 6, 2012
    Publication date: June 12, 2014
    Applicant: President and Fellows of Harvard College
    Inventors: Suzanne Walker Kahne, Jiaoyang Jiang, Michael Block Lazarus
  • Publication number: 20140062102
    Abstract: A latch includes a first locking bolt, where a first extended position of the first locking bolt defines a first locked condition and a first retracted position defines a first unlocked condition. The latch also includes a second locking bolt, where a second extended position of the second locking bolt defines a second locked condition and a second retracted position defines a second unlocked condition. A biasing member operatively connects to the first locking bolt to bias the first locking bolt in the first extended position. A lever pivotally connects to the housing and operatively connects to the first locking bolt such that movement of the lever from a closed position to an opened position causes at least the first locking bolt to move from the first extended position to the first retracted position. A locking indicator is provided in associated with the second locking bolt.
    Type: Application
    Filed: May 11, 2012
    Publication date: March 6, 2014
    Applicant: BOMBARDIER INC.
    Inventors: Robert Grant, Michael Block
  • Publication number: 20120108605
    Abstract: The present invention provides inhibitors of O-GIcNAc transferase. Typically, the inhibitors are quinolinone-6-sulfonamides. The invention also provides pharmaceutical compositions thereof and methods for using the same in diabetes and complications thereof, neurodegenerative diseases, cancers, autoimmune diseases, and inflammatory diseases.
    Type: Application
    Filed: June 1, 2010
    Publication date: May 3, 2012
    Applicant: President and Fellows of Harvard College
    Inventors: Suzanne Walker Kahne, Michael Block Lazarus, Benjamin J. Gross
  • Patent number: 8152420
    Abstract: A drill bit jig includes an elongate member, two jig securing elements and a drill bit guide. The elongate member is hollow so that one or more elongate drill bits may be stored therein. The drill bit guide includes a plurality of through holes where the axes of the through holes are parallel to the axis of the elongate member. Each of the plurality of through holes in the drill bit guide has a different diameter for accommodating drill bits of different thicknesses. The jig securing elements each include an L-shaped bolt and a door protecting material encasing one of the straight sections of the bolt.
    Type: Grant
    Filed: September 7, 2007
    Date of Patent: April 10, 2012
    Inventor: Michael Block
  • Patent number: 7896655
    Abstract: An electrical connector assembly includes a housing, a connector and a conductor. The housing extends from a mating interface to a back end along a longitudinal axis and from a top side to a mounting interface along a vertical axis. The connector is disposed at the mating interface and is configured to mate with a mating connector. The conductor extends from the electrical connector to the mounting interface to provide a conductive pathway between the mating connector and the circuit board. The conductor includes a mating portion oriented along the longitudinal axis and a mounting portion oriented along the vertical axis. One of the mating portion and the mounting portion includes a bifurcated end having opposing contact tips and the other of the mating portion and the mounting portion includes an interconnection end that is received between the contact tips to electrically couple the mating portion and the mounting portion.
    Type: Grant
    Filed: August 14, 2009
    Date of Patent: March 1, 2011
    Assignee: Tyco Electronics Corporation
    Inventors: Francis J. Blasick, Daron Wallace, Kevin Edward Weidner, Keith Richard Foltz, Michael Block, David Everts
  • Publication number: 20110039423
    Abstract: An electrical connector assembly includes a housing, a connector and a conductor. The housing extends from a mating interface to a back end along a longitudinal axis and from a top side to a mounting interface along a vertical axis. The connector is disposed at the mating interface and is configured to mate with a mating connector. The conductor extends from the electrical connector to the mounting interface to provide a conductive pathway between the mating connector and the circuit board. The conductor includes a mating portion oriented along the longitudinal axis and a mounting portion oriented along the vertical axis. One of the mating portion and the mounting portion includes a bifurcated end having opposing contact tips and the other of the mating portion and the mounting portion includes an interconnection end that is received between the contact tips to electrically couple the mating portion and the mounting portion.
    Type: Application
    Filed: August 14, 2009
    Publication date: February 17, 2011
    Applicant: TYCO ELECTRONICS CORPORATION
    Inventors: FRANCIS J. BLASICK, DARON WALLACE, KEVIN E. WEIDNER, KEITH RICHARD FOLTZ, MICHAEL BLOCK, DAVID EVERTS
  • Patent number: 7841573
    Abstract: A door guard is disclosed having a protector plate which protects a door and a support which protects a door jam and a door hinge. The protector plate is hingedly connected to the support. The protector plate rotates in response to the door opening when force is applied to the door. The present invention may further include a slide mount assembly which slideably couples the protector plate to a door. Other embodiments of a door guard also protect an overhead door and an overhead door track.
    Type: Grant
    Filed: April 28, 2009
    Date of Patent: November 30, 2010
    Inventor: Michael Block
  • Publication number: 20100090862
    Abstract: A system for monitoring and managing the energy consumption of designated devices or services obtains the point-of-use energy consumption of the designated devices or services and collects this consumption information in various formats as data. The collected data may be analyzed for peak load analysis and load shedding recommendations, among other analysis. The data may be displayed on a user interface to an energy consumer in various formats that permit the consumer to make decisions and take actions based on the displayed data or the analysis. The data may be displayed in real-time format so that the consumer may observe the instant energy consumption of a particular device. The consumer may also view a device's energy consumption to-date over a predetermined period of time. The consumer may also take an action through the system to reduce the consumer's overall energy consumption.
    Type: Application
    Filed: September 4, 2009
    Publication date: April 15, 2010
    Inventors: Nicole M. Dubrow, Michael Block
  • Patent number: 7453677
    Abstract: A power and safety control hub, integrating fault tolerant power disconnect control, software monitoring of disconnect and multi-voltage power distribution and disconnect with non-hazardous power control, EMI filtering and multi-circuit current protection in a single unit, coordinating shutdown of connected mechanical drives, commanding them to come to a controlled stop before safety power is disconnected. The hub may also integrates segmented hazardous power control and automatically discharge energy sources within connected mechanical drives at the time of safety power disconnect of hazardous power. The hub may also include internal self-protection that automatically forces a control safety power disconnect (after warning the host) if the unit should approach its maximum operating temperature, or if a cooling fan stops.
    Type: Grant
    Filed: June 15, 2005
    Date of Patent: November 18, 2008
    Assignee: Teknic, Inc.
    Inventors: Thomas John Bucella, Jeremy Michael Block, David Edward Fuchs, Francis Joseph Testa, David William Sewhuk, David Roger Larson
  • Publication number: 20070287703
    Abstract: Compounds which possess Eg5 inhibitory activity and are useful for their anti-cell-proliferation (such as anti-cancer) activity and thus in methods of treatment of the human or animal body are described.
    Type: Application
    Filed: July 21, 2005
    Publication date: December 13, 2007
    Applicant: AstraZeneca AB
    Inventors: Michael Block, Audrey Davies, Daniel Russell, Marie-Elena Theoclitou
  • Publication number: 20070249636
    Abstract: This invention relates to novel compounds having the structural formula (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment or prophylaxis of cancer.
    Type: Application
    Filed: August 16, 2005
    Publication date: October 25, 2007
    Applicant: ASTRAZENECA AB
    Inventors: Brian Aquila, Michael Block, Audrey Davies, Jayachandran Ezhuthachan, Timothy Pontz, Daniel Russell, Marie-Elena Theoclitou, XiaoLan Zheng
  • Publication number: 20070142413
    Abstract: Compounds of formula (I): and their use in the inhibition of Trk activity are described.
    Type: Application
    Filed: November 15, 2004
    Publication date: June 21, 2007
    Inventors: Michael Block, John Lee, David Scott, Haixia Wang, Tao Wang, Dingwei Yu, Yongxin Han, John Josey, Bin Wang
  • Publication number: 20060063751
    Abstract: This invention relates to novel compounds having the formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8 and R9 are as defined in the specification and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment or prophylaxis of cancer.
    Type: Application
    Filed: August 18, 2005
    Publication date: March 23, 2006
    Applicant: AstraZeneca AB
    Inventors: Brian Aquila, Michael Block, Audrey Davies, Jayachandran Ezhuthachan, Sandra Filla, Richard Luke, Timothy Pontz, Daniel Russell, Maria-Elena Theoclitou, XiaoLan Zheng