Abstract: A coated substrate comprising a coating extending over at least a part of the substrate. The coating is obtainable from a coating composition comprising (a) a polymeric binder; and (b) a feathering reducing agent comprising a carboxylic acid reactive functional group. The coated portion of the substrate comprises a pretreatment layer. The pretreatment layer is obtainable from a pretreatment composition that comprises a trivalent chromium compound. The invention extends to a method of coating a pre-treated substrate and a coated package, such as a metal can.

Abstract: A method of treatment of skin tissue with two laser devices of unequal wavelengths comprising the steps of: (1) activating the two laser devices simultaneously to produce two laser beams of unequal wavelength; (2) directing the two laser beams into a handpiece having a distal tip to direct the laser beams onto the skin tissue; (3) directing the two laser beams within the handpiece to an adjustable beam deflector; and, (4) the adjustable beam deflector directing the two laser beams onto the skin tissue to produce a pattern of laser spots simultaneously but separated from one another.

Abstract: Assemblies and methods for facilitating the assembly of aircraft wings to a fuselage are disclosed. In some embodiments, a wing unit includes features that are configured to define one of more parts of a pressure vessel that is partially defined by the fuselage portion. In some embodiments, the aircraft assemblies disclosed herein comprise one or more first structural interfaces that permit positional adjustment between the wing unit and the fuselage portion so that one or more second structural interfaces may be finished only after such positional adjustment. In some embodiments, the aircraft assemblies disclosed herein comprise one or more structural interfaces that are disposed outside of the wing unit in order to eliminate or reduce the need for assembly personnel to access the interior of the wing unit to carry out the structural assembly of the wing unit to the fuselage portion.

Abstract: Disclosed are methods and systems for the analysis activity of enzyme disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS13) in a sample. The methods and systems disclosed herein can be useful for diagnosis of thrombotic thrombocytopenic purpura in a patient.

Abstract: The present disclosure relates to a valve tray for use in a chemical process column. The valve tray includes a plurality of apertures formed therein. A plurality of valves are maintained in a spaced relationship relative to individual apertures of the plurality of apertures. An area of the individual apertures is less than an area of individual valves of the plurality of valves.

Abstract: A multi-way valve adapted to control a flow of fluid to different thermal fluid circuits includes a valve housing, a valve flow controller, and a sealing system. The valve flow controller is arranged in the valve housing to control flow through the valve housing. The sealing system is configured to seal between the valve housing and the valve flow controller.

Abstract: A coating composition comprising (a) a polyester binder material; and (b) a feathering reducing agent. The feathering reducing agent is selected from (i) an acrylic feathering reducing agent comprising a functional group selected from hydroxyl, epoxide, phosphatized epoxide and/or acid-functional; (ii) a hydroxy-functional polyester feathering reducing agent; (iii) a feathering reducing agent comprising a functional group selected from amine, amide, imine and/or nitrile; (iv) a phosphatized epoxy feathering reducing agent; (v) a phenolic resin feathering reducing agent; and/or (vi) a feathering reducing agent comprising an oxazolyl functional group. The invention extends to a substrate coated with the coating composition and use of the coating composition to reduce feathering.

Abstract: Aspects of this disclosure relate to one or more particles that move within a container in response to a magnetic field. A measurement circuit is configured to output an indication of the magnetic field based on position of the one or more particles.

Abstract: A compound helicopter includes a fuselage including a fuselage airframe, a translational thrust system coupled to the fuselage airframe and a pylon assembly subject to vibration. The pylon assembly includes a transmission and a rotor system having a main rotor assembly. The compound helicopter also includes a main rotor vibration isolation system including a plurality of augmented liquid inertia vibration eliminator units each having an isolation frequency and each coupled between the fuselage airframe and the pylon assembly to reduce transmission of the pylon assembly vibration to the fuselage airframe at the isolation frequency. Each augmented liquid inertia vibration eliminator unit includes at least one active tuning element movable to tune the isolation frequency thereof.

Abstract: Aspects of this disclosure relate to particles that can move in response to a magnetic field. A system can include a container, particles within the container, and a magnetic structure integrated with the container. The magnetic structure can magnetically interact with both an external magnetic field and the particles. Related methods are disclosed including magnetic field detection methods based on detection of particles within a container.

Abstract: The disclosure is directed to a system and methods for waking-up a wireless receiver on a wireless network. The method includes the steps of: listening, by the wireless receiver, for signals in a predetermined frequency band periodically and decoding a wake-up key; validating the wake-up key by correlating the wake-up key with values stored in a memory using a first processing device; if the wake-up key is validated, decoding at least one PHY Protocol Data Unit (PPDU) and checking the value of one or more bits of the PPDU to validate the decoded PPDU as a wake-up PPDU; if the wake-up packet is validated, decoding a wake-up address and comparing the wake-up address to the station (STA) wake-up address; if the decoded wake-up address matches the STA wake-up address, powering-up a second processing device and confirming wake-up by exchanging an encrypted frame with Access Point (AP).

Abstract: The present invention provides, inter alia, compounds having the structures of formulas described herein; pharmaceutically acceptable salts, solvates, hydrates, tautomers, and isotopic forms thereof; and compositions (e.g., pharmaceutical compositions and kits) containing one or more of the foregoing. Also provided are methods of administering and uses involving the compounds and/or pharmaceutical compositions for treating or preventing disease. The disease can be a proliferative disease, such as a cancer (e.g., a blood cancer (e.g., a leukemia or lymphoma), a brain cancer, a breast cancer, melanoma, multiple myeloma, or an ovarian cancer) a benign neoplasm, pathologic angiogenesis, or a fibrotic disease.

Abstract: Aspects of the present disclosure relate to image data verification. In examples, a discrete cosine transform (DCT) is performed on image data and used to generate a set of DCT coefficients. In some instances, multiple block sizes are used when processing the image data, such that a set of DCT coefficients is generated for each block size. The resulting sets of DCT coefficients for the plurality of block sizes may be processed according to an expected distribution to determine whether the content of the image data is likely to be authentic or likely to be altered, such that an indication may be provided in association with the image data accordingly.

Abstract: A bacterium of the class Clostridia comprising a heterologous nucleic acid molecule encoding at least one antigen, wherein the bacterium is capable of expressing the antigen in an intracellular compartment of the bacterium during anaerobic cell growth, and wherein at least one antigen is an infectious agent antigen or a tumour antigen.

Abstract: An event can be analyzed for association with a security violation. Characters or other values of event data (e.g., command-line text) associated with the event can be provided sequentially to a trained representation mapping to determine respective representation vectors. Respective indicators can be determined by applying the vectors to a trained classifer. A token in the event data can be located based on the indicators. The event's can be determined to be associated with a security violation based on the token satisfying a token-security criterion. The representation mapping can be trained by adjusting model parameters so the trained representation predicts, based on a character of training command-line text, an immediately following character in the training command-line text. The classifier can be determined based on the trained representation mapping and classification training data indicating whether respective portions of training event data are associated with security violations.

Abstract: A novel synthetic functionalized backbone polymer is provided which is a polyanionic side-chain functionalized back-bone polymer comprising a hydrophilic backbone polymer functionalized with an activated alkene or epoxy group. The functionalized backbone polymer may be combined with a free or protected thiol-containing compound to form a crosslinked hydrogel having bio-medical application, and may additionally be combined with a hydrogel matrix to yield a hydrogel system useful for in vivo delivery of cells and other therapeutic agents.

Abstract: Systems, methods and computer program products for automatically ingesting and filing documents in a database having a plurality of file locations. An electronic file having one or more documents is received. For each document in the received file, text data is identified and used to generate a plurality of suggested file locations for the received documents. Machine learning systems may be used to enhance the accuracy of suggested file locations.

Abstract: A machine includes a motor; and a transmission to drive a knife plate. The knife plate includes a plurality of knife blades. The machine further includes a die plate. The knife plate and the die plate interface at a cutting edge of the knife plate. The machine cuts feed material from larger sized pieces to smaller pieces by forcing the material through the die plate and cutting it with the knife plate.

Abstract: A shredder blade assembly is disclosed having a rotor configured to be mounted on a rotating shaft, the rotor having opposing faces with a plurality of angled knife receptacles and a plurality of knife inserts mounted within the plurality of knife receptacles. Each knife insert has two opposing faces and each opposing face comprises three cutting edges such that each knife insert has six cutting edges. Only one of the cutting edges is exposed at an outer peripheral edge of the shredder blade assembly during use. The knife inserts are configured to be removed, rotated (and flipped as needed), and re-mounted within the plurality of knife receptacles to expose another of the cutting edges at the outer peripheral edge of the shredder blade assembly. The knife insert may be triangular and mounted to expose one vertex to create a plurality of tooth/hook projections.

Abstract: Systems, methods and computer program products for automatically ingesting and filing documents in a database having a plurality of file locations. An electronic file having one or more documents is received. For each document in the received file, text data is identified and used to generate a plurality of suggested file locations for the received documents. Machine learning systems may be used to enhance the accuracy of suggested file locations.