Abstract: The present invention relates to novel mutants with cyclase activity and use thereof in a method for biocatalytic cyclization of terpenes, such as in particular for the production of isopulegol by cyclization of citronellal; a method for the preparation of menthol and methods for the biocatalytic conversion of further compounds with structural motifs similar to terpene.

Abstract: The present invention relates to novel mutants with cyclase activity and use thereof in a method for biocatalytic cyclization of terpenes, such as in particular for the production of isopulegol by cyclization of citronellal; a method for the preparation of menthol and methods for the biocatalytic conversion of further compounds with structural motifs similar to terpene.

Abstract: The present invention relates to a novel process for cyclizing geranyllinalool using the squalene-hopene cyclase from Zymomonas mobilis (Zm-SHC) or a cyclase with at least 80% sequence identity to the Zm-SHC, and cyclization products obtained in this process.

Abstract: The invention relates to a roll stand (2) for rolling, in particular cold-rolling, metal products, comprising at least one actuator (16) which can be actuated for actively damping vibrations in the roll stand (2), and at least one supporting roll (10) which is non-adjustable or can be adjusted exclusively via a readjusting device for pass line adjustment (13) of the roll stand (2) for supporting a working roll (5) and/or intermediate roll of the roll stand (2), wherein the supporting roll (10) is guided at the ends via a respective bearing unit (11) on a rack (8) of the roll stand (2).

Abstract: The present invention relates to a method for the regioselective hydroformylation of polyunsaturated acyclic hydrocarbons, which are 1, 3 butadienes, which, in the 2 position, bear a saturated or monounsaturated or polyunsaturated acyclic hydrocarbon radical. The present invention also relates to the production of secondary products of these hydroformylation products, especially of ambrox.

Abstract: The present invention relates to methods of producing sugar phosphates by enzymatic transphosphorylation, wherein the phosphoryl transfer from phosphate donor substrates to sugar substrates is catalyzed by an enzyme having alpha-glucose-1-phosphatase activity. Furthermore, the present invention relates to a biocatalyst having sucrose phosphorylase as well as alpha-glucose-1-phosphatase activity and its use. The production of an enzyme having alpha-glucose-1-phosphatase activity and its use in the transphosphorylation of sugar substrates is also presented herein.

Abstract: The present invention relates to biocatalytic methods, comprising purely enzymatic, mixed enzymatic-fermentative and purely fermentative methods, for the direct single-step conversion of L-fucitol to L-fucose, in order to easily obtain L-fucose at high amounts and levels of purity. Suitable recombinant microorganisms and fungi are further disclosed and also the use thereof in said method for the single-step conversion to L-fucose.

Abstract: Microorganisms and processes for the recombinant manufacture of clavine-type alkaloids such as cycloclavine, festuclavine, agroclavine, chanoclavine and chanoclavine aldehyde, as well as polypeptides, polynucleotides and vectors comprising such polynucleotides which can be applied in a method for the manufacture of clavine-type alkaloids are provided.

Abstract: The invention pertains to the field of production of natural products and, in particular, in the field of production of cornexistin and hydroxycornexistin. It provides polynucleotides encoding polypeptides involved in the biosynthesis of cornexistin and hydroxycornexistin as well as vectors and recombinant microorganisms comprising such polynucleotides. Also provided are methods for the production of natural products, in particular methods for the production of cornexistin and hydroxycornexistin, using such polynucleotides and polypeptides encoded therein, as well as vectors and recombinant microorganisms comprising such polynucleotides and polypeptides.

Abstract: The invention relates to a roller device (50) having a stand and two roller sets having at least two rollers (52, 53, 54, 55) disposed in a stand (51) of the roller device, wherein a roll material (56) can be fed between two rollers (53, 54) of the two roller sets for rolling, wherein at least the rollers (52, 53) of a roller set can be displaced in the rolling direction relative to the stand (51), wherein adjustment means are provided between a roller bearing for receiving the rollers and the stand, each on both sides of the roller bearing. It is thereby particularly advantageous if the circumferential speeds of the rollers, such as the working rollers, are different.

Abstract: A method for operating a casting/rolling system and to a corresponding system for casting and rolling an endless strand material. The casting/rolling system comprises a strand casting machine and a rolling train arranged downstream of the strand casting machine. The method has the following step: controlling the drive for the rollers of the first roller frame of the rolling train by means of a drive control in response to a target value specification of the pass sequence model. Furthermore, the drive of the at least one strand guiding roller is controlled by a strand guiding roller drive control in response to a target value specification of the strand casting machine drive model.

Abstract: The present invention relates to a novel process for cyclizing geranyllinalool using the squalene-hopene cyclase from Zymomonas mobilis (Zm-SHC) or a cyclase with at least 80% sequence identity to the Zm-SHC, and cyclization products obtained in this process.

Abstract: A valve drive includes a transfer arrangement with an intermediate lever arrangement having a first roller element and an intermediate lever, and a drag lever arrangement having a drag lever. The first roller element is connected to a circumferential contour of a camshaft. The intermediate lever includes a second roller element and a working curve connected to the drag lever. A slotted guide is provided for the intermediate lever arrangement which is engaged by a guide roller element. A torsion spring element with first and second ends engages the intermediate lever arrangement. The first end rests on the cylinder housing portion. The second end acts on a counter bearing rigidly connected with the intermediate lever. The first and second roller element axes are arranged to introduce a force into the intermediate lever which presses the guide roller element against the slotted guide and the first roller element against the camshaft.

Abstract: The present invention relates to a novel biocatalytic method for the production of primary and secondary amines, comprising coupled enzymatic oxidation and reduction processes simultaneously regenerating the required cofactor; making use of two enzymes—i.e. an alcohol dehydrogenase and an amine dehydrogenase—operating simultaneously in a one pot process (i.e. biocatalytic cascade). Furthermore, the overall process is redox neutral, since the hydride generated from the first oxidative step is internally recycled in the second reductive step. The invention also relates to recombinant expression systems and microorganisms procuring the required enzyme activities; and bioreactors for performing such methods.

Abstract: A device for cooling rolled stock, preferably for cooling during cold rolling, including a nozzle for applying a cooling medium to the rolled stock, wherein a cooling chamber that is in fluid communication with the nozzle and extends substantially parallel to the strip running plane is provided for applying the cooling medium to the rolled stock.

Abstract: The invention pertains to the field of production of natural products and, in particular, in the field of production of cornexistin and hydroxycornexistin. It provides polynucleotides encoding polypeptides involved in the biosynthesis of cornexistin and hydroxycornexistin as well as vectors and recombinant microorganisms comprising such polynucleotides. Also provided are methods for the production of natural products, in particular methods for the production of cornexistin and hydroxycornexistin, using such polynucleotides and polpeptides encoded therein, as well as vectors and recombinant microorganisms comprising such polynucleotides and polypeptides.

Abstract: A support roller, particularly for rolling mill systems or equipment for casting, conveying or straightening metal products, including a cylindrical roller axle, a hollow cylindrical outer ring arranged concentrically in relation to the roller axle, and a plurality of rolling bodies arranged between the roller axle and the outer ring. The roller axle further including a cavity, at least in certain sections between its central axis and a load introduction point. Due to the provision of the cavity the load rating and the service life of the support roller are increased.

Abstract: The present invention relates to novel mutants with cyclase activity and use thereof in a method for biocatalytic cyclization of terpenes, such as in particular for the production of isopulegol by cyclization of citronellal; a method for the preparation of menthol and methods for the biocatalytic conversion of further compounds with structural motifs similar to terpene.

Abstract: The present invention relates to novel mutants with cyclase activity and use thereof in a method for biocatalytic cyclization of terpenes, such as in particular for the production of isopulegol by cyclization of citronellal; a method for the preparation of menthol and methods for the biocatalytic conversion of further compounds with structural motifs similar to terpene.