Abstract: The present invention relates to a method for increasing adhesion strength between a surface of a metal, a metal alloy or a metal oxide and a surface of an organic material comprising as a main step contacting of at least one section of said metal, metal alloy or metal oxide with a specific azole silane compound, a specific azole silane oligomer, or a mixture comprising said compound and/or said oligomer. Furthermore, the present invention relates to a use of said specific azole silane compound, said specific azole silane oligomer, or said mixture in a method for increasing adhesion strength between a surface of a metal, a metal alloy or a metal oxide and a surface of an organic material.

Abstract: Described is an apparatus of a User Equipment (UE) operable to communicate with an Evolved Node-B (eNB) on a wireless network. The apparatus may comprise a first circuitry, a second circuitry, and a third circuitry. The first circuitry may be operable to process a configuration transmission carrying a half-tone shifting indicator. The second circuitry may be operable to select one or more subcarrier frequencies for Uplink (UL) transmission based on the half-tone shifting indicator. The third circuitry may be operable to generate a UL transmission for the one or more subcarrier frequencies. The half-tone shifting indicator may have a first value indicating application of a half-subcarrier offset, and a second value indicating no application of the half-subcarrier offset.

Abstract: A method includes providing a cartridge and the cartridge includes a slot for receiving a microfluidic chip having a set of first channels. The cartridge also includes a set of second channels and each channel of the set of second channels is coupleable to a different channel of the set of first channels during use with the microfluidic chip. The cartridge also includes an indent configured for engagement and alignment of the cartridge during use. The method also includes inserting the cartridge into a device, such that the cartridge engages a first biasing member of the device configured for alignment of the cartridge in a first direction. The first biasing member is configured to bias movement of the cartridge into locking position with a notch of the device.

Abstract: A bootstrap circuit for generating an output signal through a pre-charge operation and a sample operation, includes: a sampler including a sampling switch configured to sample an input signal, a first protection switch connected between an input node and the sampling switch, and a second protection switch connected between the sampling switch and an output node; and a driver configured to drive the sampler based on a power supply voltage and the input signal.

Abstract: Inspection robots with independent drive module suspension are described. An example inspection robot may have a housing with a first connector on a first side of the housing, and a second connector on a second side of the housing. A first drive module, having at least one wheel and a first motor, may be operatively coupled to the first connector, and a second drive module, having at least one wheel and a first motor, may be operatively coupled to the second connector. The first and second drive modules may be coupled by a drive connector.

Abstract: A multiplexer includes a charging circuit; a plurality of sampling switches receiving a plurality of input signals; and a plurality of boosting circuits connected between the sampling switches and the charging circuit and sharing the charging circuit. First and second charging switches of the charging circuit are controlled by a first clock signal. Each of the boosting circuits includes a first boosting switch connected to a first node of the charging circuit and a gate of one of the sampling switches, a second boosting switch connected between a second node of the charging circuit and the one sampling switch, and a level shifter configured to control the first boosting switch and the second boosting switch in response to a second clock signal and a selection signal.

Abstract: Inspection robots with removeable interface plates and method for configuring payload interfaces are described. An example robot may include a payload, with at least one sensor, mounted to a housing of the inspection robot. The housing may include a removeable interface plate coupled to the at least one sensor and to an electronic board, the electronic board positioned within the housing. The removeable interface plate may define an electrical coupling interface compatible with the payload, and the electronic board may include an electrical processing configuration compatible with the payload.

Abstract: Provided herein are antibodies or antigen-binding fragments thereof, e.g., monoclonal antibodies or antigen binding fragments thereof, that specifically bind to ENTPD2 (e.g., human ENTPD2 protein), and methods of using these antibodies or antigen-binding fragments. The present invention also relates to combination therapies comprising an anti-human ENTPD2 antibody or antigen binding fragment and at least one additional therapeutic agent, and methods of using these combination therapies.

Abstract: An apparatus and methods of use thereof, the apparatus comprising: a medical device, configured to reside and to be manipulated within a first lumen; and a driving system, configured to manipulate—and/or control—the medical device, via a second lumen. The driving system comprising: a catheter, configured to be inserted into—and to navigate—or to be navigated—within the second lumen; and a driver, configured to travel within the catheter, and to remotely manipulate—and/or control—the medical device residing in the first lumen.

Abstract: A method for providing localized treatment at a target site in the brain of a patient is provided. The method comprises providing a system comprising a miniature device configured to carry one or more therapeutic components for performing the treatment, and an external system configured to direct the miniature device; inserting the miniature device to a starting location within the patient; operating the external system to direct the miniature device to travel along an access path from the starting location to the target site; and administering the therapeutic component at the target site. A system for performing the method is further provided.

Abstract: A system for facilitating performing a therapeutic activity at a predetermined treatment site in a patient is provided. The system comprises an elongated miniature device extending along a longitudinal axis spanning between a distal cutting end formed with a sharp cutting portion, and a blunt proximal abutting end. The elongated body comprises a substantially non-convex bottom surface extending substantially between the cutting end and the abutting end. The system further comprises a driving device configured to generate a varying magnetic field to remotely control motion of the miniature device.

Abstract: A digital droop detector for detecting whether a droop occurs in a power supply voltage, may include processing circuitry configured to, detect a voltage level change of a power supply voltage in response to a clock signal, the detecting the voltage level change including converting the detected voltage level change into a first code, correct at least one nonlinearity included in the first code, the correcting including converting the first code into a second code and a target range, and adjust a delay magnitude of the clock signal based on the second code.

Abstract: Disclosed are devices for improving viability of isolated islets or ?-cells and stimulating insulin production from isolated islets or ?-cells and uses thereof for treating type 1 diabetes.

Abstract: Provided herein are compositions and methods for diagnosis and therapy through targeted nano-delivery to injured brain endothelium. In some aspects, the compositions comprise a population of polyester derived nanoparticles, wherein each polyester derived nanoparticle comprises a) a therapeutic agent encapsulated therein for treating traumatically injured, inflamed, diseased, or disrupted endothelial cells, and b) a targeting ligand bound to the nanoparticle, wherein the targeting ligand binds to a biomarker for the injured, inflamed, diseased, or disrupted endothelial cells, are provided. The nanoparticles can be used for targeting difficult-to-reach injury sites, including the blood brain barrier and brain tissue.

Abstract: Disclosed are devices for improving viability of isolated islets or ?-cells and stimulating insulin production from isolated islets or ?-cells and uses thereof for treating type 1 diabetes.