Patents by Inventor Michael Chorev

Michael Chorev has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Parathyroid hormone antagonists
    Patent number: 4968669
    Abstract: The present invention relates to the use of peptide hormone analogues as inhibitors of their respective naturally occurring peptide hormone. The structure of the peptide hormone analogues is exemplified by parathyroid hormone wherein Gly.sup.12 is substituted by D-Trp, L-Trp, L- or D- alpha- or beta-naphthylalanine, or D- or L- alpha-MeTrp.
    Type: Grant
    Filed: April 21, 1989
    Date of Patent: November 6, 1990
    Assignee: Merck & Co., Inc.
    Inventors: Michael Rosenblatt, Michael Chorev
  • Phenyl carbamates
    Patent number: 4948807
    Abstract: Phenyl carbamates of the general formula ##STR1## wherein R.sub.1 to R.sub.5 are as defined in the claims, are useful as pharmaceuticals.
    Type: Grant
    Filed: March 8, 1989
    Date of Patent: August 14, 1990
    Assignee: Proterra AG
    Inventors: Marta W. Rosin, Michael Chorev, Zeev Tashma
  • Parathyroid hormone antagonists with simplified synthetic methodology
    Patent number: 4771124
    Abstract: The present invention relates to the use of peptide hormone analogues as inhibitors of their respective naturally occurring peptide hormone and methods of synthesis of such analogues. The structure of the peptide hormone analogues is exemplified by parathyroid hormone wherein Trp.sup.23 is substituted by L-Phe or other hydrophobic amino acids such as Leu, Nle, Val, Tyr, beta-napthylalanine and alpha-napthylalanine.
    Type: Grant
    Filed: May 26, 1987
    Date of Patent: September 13, 1988
    Assignee: Merck & Co., Inc.
    Inventors: Michael Rosenblatt, Lynn H. Caporale, Ruth F. Nutt, Jay J. Levy, Michael Chorev