Patents by Inventor Michael D. Ward

Michael D. Ward has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090042310
    Abstract: The present invention comprises methods and systems that use acoustic radiation pressure.
    Type: Application
    Filed: September 26, 2008
    Publication date: February 12, 2009
    Inventors: Michael D. Ward, Gregory Kaduchak
  • Publication number: 20090042239
    Abstract: The present invention comprises methods and systems that use acoustic radiation pressure.
    Type: Application
    Filed: September 26, 2008
    Publication date: February 12, 2009
    Inventors: Michael D. Ward, Gregory Kaduchak
  • Publication number: 20090029870
    Abstract: The present invention comprises methods and systems that use acoustic radiation pressure.
    Type: Application
    Filed: September 26, 2008
    Publication date: January 29, 2009
    Inventors: Michael D. Ward, Gregory Kaduchak
  • Publication number: 20080245745
    Abstract: An apparatus for acoustic concentration of particles in a fluid flow includes a substantially acoustically transparent membrane and a vibration generator that define a fluid flow path therebetween. The fluid flow path is in fluid communication with a fluid source and a fluid outlet and the vibration generator is disposed adjacent the fluid flow path and is capable of producing an acoustic field in the fluid flow path. The acoustic field produces at least one pressure minima in the fluid flow path at a predetermined location within the fluid flow path and forces predetermined particles in the fluid flow path to the at least one pressure minima.
    Type: Application
    Filed: April 9, 2007
    Publication date: October 9, 2008
    Inventors: Michael D. Ward, Gregory Kaduchak
  • Publication number: 20080245709
    Abstract: An apparatus for separating particles from a medium includes a capillary defining a flow path therein that is in fluid communication with a medium source. The medium source includes engineered acoustic contrast capture particle having a predetermined acoustic contrast. The apparatus includes a vibration generator that is operable to produce at least one acoustic field within the flow path. The acoustic field produces a force potential minima for positive acoustic contrast particles and a force potential minima for negative acoustic contrast particles in the flow path and drives the engineered acoustic contrast capture particles to either the force potential minima for positive acoustic contrast particles or the force potential minima for negative acoustic contrast particles.
    Type: Application
    Filed: April 9, 2007
    Publication date: October 9, 2008
    Inventors: Gregory Kaduchak, Michael D. Ward
  • Publication number: 20080248500
    Abstract: The present invention provides a protein-based biomarker, ApoA-II isoform, that is useful in determining prostate cancer status in a patient. In particular, the biomarker of this invention is useful to classify a biological sample as prostate cancer or non-prostate cancer. The ability of ApoA-II to detect disease in patients with a normal prostate-specific antigen (PSA) makes the biomarker of this invention useful in identifying indolent disease. The biomarker can be detected by SELDI mass spectrometry, HPLC, PAGE and Western blotting.
    Type: Application
    Filed: January 6, 2006
    Publication date: October 9, 2008
    Applicant: Eastern Virginia Medical School
    Inventors: O John Semmes, Gunjan Malik, Michael D. Ward
  • Patent number: 7145002
    Abstract: A process for preparing a crystalline, carbapenem monosodium salt of formula IIa: characterized by the steps a) adding about 10 to 30% of an organic solvent to an aqueous solution of the carbapenem, b) cooling the resulting solution to less than ?5° C., c) adjusting the pH using a solution containing an acid in an organic solvent to give the appropriate pH for crystallization, and d) crystallizing the compound by adding methanol, and a C2-5 alcohol at between ?5 and ?25° C.
    Type: Grant
    Filed: September 20, 2002
    Date of Patent: December 5, 2006
    Assignee: Merck & Co. Inc.
    Inventors: Karel M. J. Brands, Raymond Cvetovich, Louis S. Crocker, Michael D. Ward, Amar J. Mahajan, Robert M. Wenslow, John M. Williams, Daniel R. Sidler, Charles Orella, Elizabeth S. Fisher, Ronald Jobson
  • Publication number: 20040262455
    Abstract: A fuel inerting system, comprising a first supply means (2) to supply an inert gas to a fuel tank (8) to scrub the fuel therein when the ullage (16) of the fuel tank is inert, and a second supply means (4) to supply the inert gas to scrub the fuel (6) therein when the ullage of the fuel tank is not inert, the first and second supply means (2, 4) being individually operable by means of a valve arrangement (10), in such a manner that only one of the supply means is operable at any given time. The inert gas consists of nitrogen enriched air, produced by passing air from a pressurised area of the aircraft through a nitrogen separator located within, but removable from, the aircraft.
    Type: Application
    Filed: July 26, 2002
    Publication date: December 30, 2004
    Inventors: Christine Picot, Michael D Ward
  • Patent number: 6830219
    Abstract: A fuel inerting system, comprising a first supply means (2) to supply an inert gas to a fuel tank (8) to scrub the fuel therein when the ullage (16) of the fuel tank is inert, and a second supply means (4) to supply the inert gas to scrub the fuel (6) therein when the ullage of the fuel tank is not inert, the first and second supply means (2, 4) being individually operable by means of a valve arrangement (10), in such a manner that only one of the supply means is operable at any given time. The inert gas consists of nitrogen enriched air, produced by passing air from a pressurized area of the aircraft through a nitrogen separator located within, but removable from, the aircraft.
    Type: Grant
    Filed: July 26, 2002
    Date of Patent: December 14, 2004
    Assignee: Bae Systems plc
    Inventors: Christine Picot, Michael D Ward
  • Publication number: 20040235817
    Abstract: A process for preparing a crystalline, carbapenem monosodium salt of formula IIa: 1
    Type: Application
    Filed: January 27, 2004
    Publication date: November 25, 2004
    Inventors: Karel M. J. Brands, Raymond Cvetovich, Louis S Crocker, Michael D Ward, Amar J Mahajan, Robert M Wenslow, John M Williams, Daniel R Sidler, Charles Orella, Elizabeth S Fisher
  • Patent number: 6505748
    Abstract: A rack for dispensing and storing spooled material. The rack has at least one platform for storing the spooled material, a support for maintaining the platform above the floor level, a pair of arms attached to the platform, and an axle for rotatably receiving the spooled material for dispensing there from. The axle is substantially horizontally supported by the arms away from a peripheral edge of the platform. In one embodiment, the arms include a plurality of notches for supporting the axle in one of a plurality of positions spaced from the platform. In another embodiment, the axle has one end pivotally attached to one of the arms and the other end received in a notch in the other arm.
    Type: Grant
    Filed: April 24, 2000
    Date of Patent: January 14, 2003
    Inventor: Michael D. Ward
  • Publication number: 20010054596
    Abstract: A rack is provided for dispensing and storing spooled material. The rack has at least one platform for storing spooled material, a support for maintaining the platform above the floor level, and an axle for rotatably receiving the spools. The axle is at least substantially horizontally displaced from the peripheral edge of the platform.
    Type: Application
    Filed: April 24, 2000
    Publication date: December 27, 2001
    Inventor: Michael D. Ward
  • Patent number: 5846669
    Abstract: A hybrid electrolyte system for fuel cells and other electrochemical reactors comprising an acid electrolyte, a base electrolyte, and a proton permeable dense phase separating the acid electrolyte from the base electrolyte.
    Type: Grant
    Filed: January 16, 1996
    Date of Patent: December 8, 1998
    Assignee: Illinois Institute of Technology
    Inventors: Eugene S. Smotkin, Thomas E. Mallouk, Michael D. Ward, Kevin L. Ley
  • Patent number: 5764068
    Abstract: A method using quartz resonators probes dynamically the mechanical characteristics of thin films. This method probes the film properties at the anti-resonance frequency where the vibrational amplitude is smallest, minimizing nonlinear contributions in the dependence of the film mechanical characteristics on the resonator electrical characteristics. Determination of the mechanical characteristics involves impedance analysis, transformation of .vertline.Y.vertline. and .theta. data into a linear form so that the conductance and susceptance at the frequency of minimum absolute admittance can be accurately determined, and use of a two-dimensional Newton-Raphson numerical method to determine the values of the storage modulus G', loss modulus G", as well as various other film and resonator properties.
    Type: Grant
    Filed: July 25, 1996
    Date of Patent: June 9, 1998
    Assignee: California Insitute of Technology
    Inventors: Alexander Katz, Michael D. Ward
  • Patent number: 5679033
    Abstract: A terminal capacitor cover assembly having a screw portion and a jacket portion for complementarily fitting a terminal for a capacitor. This assembly provides an easy retrofit for capacitor terminals to equip them with a aesthetically acceptable and functionally superior alternative material. The assembly can be constructed of material equivalent to the operatively connected electrical lead, thus reducing the anodization and cross metallic oxidation of the capacitor terminal.
    Type: Grant
    Filed: September 21, 1995
    Date of Patent: October 21, 1997
    Assignee: Yosemite Investment, Inc.
    Inventors: Russell E. Eavey, Michael D. Ward
  • Patent number: 5501986
    Abstract: A piezoelectric crystal-based specific binding assay in which a sol is used to increase the mass of binding reagents to amplify responses to analyte.
    Type: Grant
    Filed: July 28, 1994
    Date of Patent: March 26, 1996
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Michael D. Ward, Richard C. Ebersole
  • Patent number: 5135852
    Abstract: The invention relates to a piezoelectric biosensor device and also to a method and a system utilizing a piezoelectric biosensor device for detecting metabolic growth requirements, antibiotic responses, and the specific bacterial products of microorganisms. When a microorganism is grown in an appropriate nutrient medium containing a metabolic product responsive polymer, metabolic products of the organism acidify the medium and precipitate a polymer metabolic product complex which deposits or accumulates on the surface of a piezoelectric biosensor device. The mass change on the surface of the device resulting from this deposit produces a change in the resonant frequency of the piezoelectric biosensor device which can be used to determine the growth and type of microorganism.
    Type: Grant
    Filed: July 25, 1989
    Date of Patent: August 4, 1992
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Richard C. Ebersole, Robert P. Foss, Michael D. Ward
  • Patent number: 4999284
    Abstract: A quartz crystal microbalance assay in which the binding of analyte to a surface on or near a quartz crystal microbalance (QCM) is detected by a conjugate which comprises an enzyme capable of catalyzing the conversion of a substrate to a product capable of accummulating on or reacting with a surface of the QCM leading to a mass change and, hence, a change in resonant frequency.
    Type: Grant
    Filed: April 6, 1988
    Date of Patent: March 12, 1991
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Michael D. Ward, Richard C. Ebersole
  • Patent number: 4781803
    Abstract: Improved electrolytic processes employing oxygen anodes. The improvement comprises the step of conducting a electrolysis process in an electrolytic cell having a platinum based amorphous metal alloy oxygen anode having the formulaPt.sub.p A.sub.a D.sub.dwhereA is Cr, Mo, W, Fe, Os, Ir, Cu, Ni, Rh, Pd, Ag, Ti, Ru, Nb, V, Ta, Au and mixtures thereof;D is B, C, Si, Al, Ge, P, As, Sb, Sn and mixtures thereof;p ranges from about 40 to 92;a ranges from about 0 to 40; andd ranges from about 8 to 60, with the proviso that p+a+d=100.
    Type: Grant
    Filed: June 16, 1986
    Date of Patent: November 1, 1988
    Assignee: The Standard Oil Company
    Inventors: Jonathan H. Harris, Michael A. Tenhover, Robert K. Grasselli, Michael D. Ward
  • Patent number: 4725440
    Abstract: An antifungal pastille formulation, preferably containing nystatin as the antifungal agent, is provided which is soft and smooth in texture and when dissolved slowly in the mouth does not cause irritation of and will not adhere to oral mucosa and yet distributes nystatin in sufficiently high saliva concentrations, throughout the oral cavity, for long enough periods of time so as to be particularly effective in the treatment of candidiasis in the oral cavity and esophagus. A method for treating candidiasis in the oral cavity and esophagus employing the antifungal pastille and a method for preparing a nystatin pastille formulation are also provided.
    Type: Grant
    Filed: May 24, 1984
    Date of Patent: February 16, 1988
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Frank Ridgway, Michael D. Ward