Patents by Inventor Michael Keidar

Michael Keidar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10023858
    Abstract: A method for elevating a TRAIL-R1 expression in cancer cells to induce apoptosis. The method comprises the steps of receiving electrical energy having a specific voltage, frequency and power from an electrosurgical generator, up-converting the voltage and down-converting the frequency with a high voltage transformer having a primary coil and a secondary coil, the secondary coil having a larger number of turns than the primary coil, applying said converted electrical energy to an electrode in an electrosurgical hand piece, flowing an inert gas through said electrosurgical hand piece to produce a cold plasma at a distal end of said electrosurgical hand piece; and applying said cold plasma to cancer cells for 1 to 3 minutes. The inert gas may comprise, for example, helium or argon. In a preferred embodiment the cold plasma is applied to cancer cells for about 2 minutes.
    Type: Grant
    Filed: November 5, 2015
    Date of Patent: July 17, 2018
    Assignee: U.S. Patent Innovations, LLC
    Inventors: Jerome Canady, Alexey Shashurin, Michael Keidar, Taisen Zhuang, Arpitha Parthasarathy
  • Publication number: 20180193093
    Abstract: A system and method of treating an area having cancerous cells. The system includes a plasma device to generate a plasma jet directed at the area having cancerous cells. A magnetic field generator generates a magnetic field directed at the area having cancerous cells. A controller is coupled to the plasma device and the magnetic field generator to control the plasma jet generated by the plasma device and control the magnetic field generated by the magnetic field generator.
    Type: Application
    Filed: June 28, 2016
    Publication date: July 12, 2018
    Inventors: Michael Keidar, Xiaoqian Cheng, Alexey Shashurin, Jonathan Sherman
  • Patent number: 9999462
    Abstract: A system that does conversion from regular hot plasma produced by ESU to cold plasma which is thermally harmless for the tissue. The system is comprised of Conversion Unit and Cold Plasma Probe. Output signal for ESU connects to CU along with Helium flow. The CU converts signal from ESU and send it to the output connector along with helium flow. Cold Plasma Probe is connected directly to the CU output. At the end of the CPP probe cold plasma is produced.
    Type: Grant
    Filed: May 29, 2015
    Date of Patent: June 19, 2018
    Assignee: U.S. Patent Innovations, LLC
    Inventors: Jerome Canady, Alexey Shashurin, Michael Keidar, Taisen Zhuang
  • Publication number: 20170370353
    Abstract: A satellite thruster increases satellite efficiency. The Linear Actuated ?CAT has a stepper motor to move the ablative electrode forward. A LabVIEW program and Arduino microcontroller are used to analyze the Linear Actuated ?CAT to determine how many steps are required for re-ignition, arc current, and the validity of the feed system. Results from testing show that micro-stepping the stepper motor is an effective way to replenish the cannibalized electrode for propellant.
    Type: Application
    Filed: June 22, 2017
    Publication date: December 28, 2017
    Inventors: Michael KEIDAR, George TEEL, Samantha A. HURLEY
  • Patent number: 9839896
    Abstract: A system and method for producing graphene includes a discharge assembly and a substrate assembly. The discharge assembly includes a cathode and an anode, which in one embodiment are offset from each other. The anode produces a flux stream that is deposited onto a substrate. A collection device removes the deposited material from the rotating substrate. The flux stream can be a carbon vapor, with the deposited flux being graphene.
    Type: Grant
    Filed: November 19, 2014
    Date of Patent: December 12, 2017
    Assignee: The George Washington University
    Inventors: Michael Keidar, Alexey Shashurin
  • Publication number: 20170313444
    Abstract: A CubeSat satellite has a solar cell and an arc propulsion system. The arc propulsion system includes a power source, a first lead coupled to the power source and to a cathode, and a second lead coupled to the power source and to an anode. The solar cell is used as the cathode of the propulsion system.
    Type: Application
    Filed: April 28, 2017
    Publication date: November 2, 2017
    Inventors: Michael KEIDAR, Joel SLOTTEN
  • Publication number: 20170217776
    Abstract: A system and method for producing graphene includes a heating block, substrate, motor and collection device. The substrate is arranged about the heating block and is configured to receive heat from the heating block. A motor is connected to the substrate to rotate the substrate about the heating block. A cathode and anode are configured to direct a flux stream for deposit onto the rotating substrate. A collection device removes the deposited material from the rotating substrate. A heating element is embedded in the heating block and imparts heat to the heating block. The heating block is made of cement or other material that uniformly disperses the heat from the heating element throughout the heating block. The flux stream can be a carbon vapor, with the deposited flux being graphene.
    Type: Application
    Filed: November 8, 2016
    Publication date: August 3, 2017
    Applicant: The George Washington University
    Inventors: Michael Keidar, Alexey Shashurin
  • Publication number: 20170183632
    Abstract: A method for treating cancer stem cells with cold atmospheric plasma using a cold atmospheric plasma system The method comprises the steps of placing an exit port of a cold plasma delivery device 5 cm or less from target cancer stem cells, flowing the inert gas from the source through the housing at a flow rate of 5-10 ml/minute, applying electrosurgical energy of 2-5 kV at a frequency of 20-35 kHz to at least one of the central electrode and the ring electrode to produce a cold plasma jet from the exit port, directing the cold plasma jet onto the target cancer stem cells, and applying the cold plasma jet onto the target cancer stem cells for at least 2 minutes. In a preferred embodiment the inert gas is helium.
    Type: Application
    Filed: December 28, 2016
    Publication date: June 29, 2017
    Inventors: Barry Trink, Michael Keidar, Jerome Canady
  • Publication number: 20170183631
    Abstract: A method for preparing cold atmospheric plasma stimulated cell culture media with a cold atmospheric plasma system having a delivery port out of which an inert gas flows. The inert gas may be helium. The method comprises the steps of placing a cell culture media in a first well, the first well having a bottom and having a diameter greater than 20 mm; wherein the cell culture media placed in the first well has a volume of 4 ml or less, treating the cell culture media in the first well with cold atmospheric plasma, wherein the treating is performed with a gap between the delivery port and the bottom of the first well is between 2.5 cm and 3.5 cm, and transferring a portion of the treated media to cultured cancer cells in a second well. The cold atmospheric plasma may be applied for 0.5 minutes to 2 minutes.
    Type: Application
    Filed: December 28, 2016
    Publication date: June 29, 2017
    Inventors: Michael Keidar, Jerome Canady
  • Patent number: 9517847
    Abstract: A magnetically enhanced micro-cathode thruster assembly provides long-lasting thrust. The micro-cathode thruster assembly includes a tubular housing, a tubular cathode, an insulator, an anode and a magnetic field. The tubular housing includes an open distal end. The tubular cathode is housed within the housing and includes a distal end positioned proximate the open distal end of the housing. The insulator is in contact with the cathode forming an external cathode-insulator interface. The anode is housed within the housing, proximate the open distal end of the housing. The magnetic field is positioned at or about the external cathode-insulator interface and has magnetic field lines with an incidence angle of about 20 to about 30 degrees and preferably about 30 degrees relative to the external cathode-insulator interface.
    Type: Grant
    Filed: October 1, 2014
    Date of Patent: December 13, 2016
    Assignee: The George Washington University
    Inventors: Michael Keidar, Alexey Shashurin, Tai Sen Zhuang
  • Publication number: 20160273524
    Abstract: A thruster for a micro-satellite is disclosed. The thruster includes a voltage source, an inductor and a resistor. A switching device is coupled to the inductor and the resistor. The thruster includes an exterior electrode composed of a first propellant, an insulator located coaxially within the exterior electrode and an interior electrode composed of a second propellant located coaxially to the insulator and the exterior electrode. An exterior housing has a proximate end and an opposite distal end with a thrust channel. The exterior housing holds the exterior electrode, the insulator and the interior electrode. The switching device is coupled to either the exterior electrode or the interior electrode. The switching device is switched to pulse voltage from the inductor to create an arc between the exterior electrode and the interior electrode. Either the exterior electrode or the interior electrode may serve as a cathode to generate a plasma jet.
    Type: Application
    Filed: February 17, 2014
    Publication date: September 22, 2016
    Inventors: Michael Keidar, Dereck Chiu, Taisen Zhuang, George Teel, Alexy Shashurin
  • Publication number: 20160138006
    Abstract: A method for elevating a TRAIL-R1 expression in cancer cells to induce apoptosis. The method comprises the steps of receiving electrical energy having a specific voltage, frequency and power from an electrosurgical generator, up-converting the voltage and down-converting the frequency with a high voltage transformer having a primary coil and a secondary coil, the secondary coil having a larger number of turns than the primary coil, applying said converted electrical energy to an electrode in an electrosurgical hand piece, flowing an inert gas through said electrosurgical hand piece to produce a cold plasma at a distal end of said electrosurgical hand piece; and applying said cold plasma to cancer cells for 1 to 3 minutes. The inert gas may comprise, for example, helium or argon. In a preferred embodiment the cold plasma is applied to cancer cells for about 2 minutes.
    Type: Application
    Filed: November 5, 2015
    Publication date: May 19, 2016
    Inventors: Jerome Canady, Alexey Shashurin, Michael Keidar, Taisen Zhuang, Arpitha Parthasarathy
  • Publication number: 20160038907
    Abstract: A system and method for producing graphene includes a discharge assembly and a substrate assembly. The discharge assembly includes a cathode and an anode, which in one embodiment are offset from each other. The anode produces a flux stream that is deposited onto a substrate. A collection device removes the deposited material from the rotating substrate. The flux stream can be a carbon vapor, with the deposited flux being graphene.
    Type: Application
    Filed: November 19, 2014
    Publication date: February 11, 2016
    Inventors: Michael Keidar, Alexey SHASHURIN
  • Publication number: 20150342663
    Abstract: A system that does conversion from regular hot plasma produced by ESU to cold plasma which is thermally harmless for the tissue. The system is comprised of Conversion Unit and Cold Plasma Probe. Output signal for ESU connects to CU along with Helium flow. The CU converts signal from ESU and send it to the output connector along with helium flow. Cold Plasma Probe is connected directly to the CU output. At the end of the CPP probe cold plasma is produced.
    Type: Application
    Filed: May 29, 2015
    Publication date: December 3, 2015
    Inventors: Jerome Canady, Alexey Shashurin, Michael Keidar, Taisen Zhuang
  • Publication number: 20150052874
    Abstract: A magnetically enhanced micro-cathode thruster assembly provides long-lasting thrust. The micro-cathode thruster assembly includes a tubular housing, a tubular cathode, an insulator, an anode and a magnetic field. The tubular housing includes an open distal end. The tubular cathode is housed within the housing and includes a distal end positioned proximate the open distal end of the housing. The insulator is in contact with the cathode forming an external cathode-insulator interface. The anode is housed within the housing, proximate the open distal end of the housing. The magnetic field is positioned at or about the external cathode-insulator interface and has magnetic field lines with an incidence angle of about 20 to about 30 degrees and preferably about 30 degrees relative to the external cathode-insulator interface.
    Type: Application
    Filed: October 1, 2014
    Publication date: February 26, 2015
    Inventors: Michael KEIDAR, Alexey SHASHURIN, Tai Sen ZHUANG
  • Publication number: 20140378892
    Abstract: A device uses cold plasma to treat cancerous tumors. The device has a gas supply tube with a delivery end. The gas supply tube is configured to carry a gas to the delivery end. A syringe is provided having an opening. The syringe is connected to the supply tube and configured to carry the gas to the opening. A first electrode is positioned inside said syringe, and a second electrode is positioned adjacent to the opening. The first and second electrodes excite the gas to enter a cold plasma state prior to being discharged from the opening of the syringe. An endoscopic tube can be used instead of the syringe. An exhaust tube can be provided to remove gas introduced into the body cavity by the cold plasma jet.
    Type: Application
    Filed: June 1, 2012
    Publication date: December 25, 2014
    Inventors: Michael Keidar, Charanjeet Guron, Barry Trink, Alexey Shashurin
  • Patent number: 8875485
    Abstract: A magnetically enhanced micro-cathode thruster assembly for providing long-lasting thrust is provided. The micro-cathode thruster assembly includes a tubular housing, a tubular cathode, an insulator, an anode and a magnetic field. The tubular housing includes an open distal end. The tubular cathode is housed within the housing and includes a distal end positioned proximate the open distal end of the housing. The insulator is in contact with the cathode forming an external cathode-insulator interface. The anode is housed within the housing, proximate the open distal end of the housing. The magnetic field is positioned at or about the external cathode-insulator interface and has magnetic field lines with an incidence angle of about 0 to about 90 degrees and preferably about 4 to about 30 degrees relative to the external cathode-insulator interface.
    Type: Grant
    Filed: April 6, 2011
    Date of Patent: November 4, 2014
    Assignee: The George Washington University
    Inventors: Michael Keidar, Alexey Shashurin, Taisen Zhuang
  • Publication number: 20130327637
    Abstract: A system and method for producing graphene includes a heating block, substrate, motor and collection device. The substrate is arranged about the heating block and is configured to receive heat from the heating block. A motor is connected to the substrate to rotate the substrate about the heating block. A cathode and anode are configured to direct a flux stream for deposit onto the rotating substrate. A collection device removes the deposited material from the rotating substrate. A heating element is embedded in the heating block and imparts heat to the heating block. The heating block is made of cement or other material that uniformly disperses the heat from the heating element throughout the heating block. The flux stream can be a carbon vapor, with the deposited flux being graphene.
    Type: Application
    Filed: June 5, 2013
    Publication date: December 12, 2013
    Applicant: The George Washington University
    Inventors: Michael KEIDAR, Alexey SHASHURIN
  • Publication number: 20110258981
    Abstract: A magnetically enhanced micro-cathode thruster assembly for providing long-lasting thrust is provided. The micro-cathode thruster assembly includes a tubular housing, a tubular cathode, an insulator, an anode and a magnetic field. The tubular housing includes an open distal end. The tubular cathode is housed within the housing and includes a distal end positioned proximate the open distal end of the housing. The insulator is in contact with the cathode forming an external cathode-insulator interface. The anode is housed within the housing, proximate the open distal end of the housing. The magnetic field is positioned at or about the external cathode-insulator interface and has magnetic field lines with an incidence angle of about 0 to about 90 degrees and preferably about 4 to about 30 degrees relative to the external cathode-insulator interface.
    Type: Application
    Filed: April 6, 2011
    Publication date: October 27, 2011
    Applicant: THE GEORGE WASHINGTON UNIVERSITY
    Inventors: Michael KEIDAR, Alexey SHASHURIN, Taisen ZHUANG
  • Patent number: 7516610
    Abstract: A scalable flat-panel nano-particle MEMS/NEMS thruster includes a grid having a plurality of electrodes to establish electrical fields. A liquid is disposed in a liquid reservoir of the grid. The liquid is positioned within the electrical fields. A plurality of nano-particles are suspended in the liquid. A plurality of MEMS and NEMS micron-size vias are disposed in the grid. The electrical fields extract the plurality of nano-particles from the liquid and accelerate the nano-particles in the vias to provide propulsion system thrust.
    Type: Grant
    Filed: October 6, 2006
    Date of Patent: April 14, 2009
    Assignee: The Regents of the University of Michigan
    Inventors: Brian E. Gilchrist, Alec D. Gallimore, Michael Keidar, Louis Musinski, Thomas M. Liu