Abstract: This disclosure is drawn to substituted pyridine compounds and compositions, and associated methods, useful for inhibition of SARM1 activity and/or for treating or preventing a neurological diseases.

Abstract: This disclosure is drawn to substituted pyridine compounds and compositions, and associated methods, useful for inhibition of SARM1 activity and/or for treating or preventing a neurological diseases.

Abstract: A method of generating a content library includes receiving a generate command that indicates a design application file to generate a content library, identifying a set of primitives from the design application file, and generating a content library from the set of primitives. In some cases, the method further includes receiving an import command to import content from a file that is a same format type as the content library and in response to receiving the import command, extracting appropriate values from associated primitives in the file and importing the appropriate values to the design application file. In some cases, the method further includes receiving an export command to export content from the design application file to a different application file of a specified format type and providing the content library in the specified format type.

Abstract: This disclosure relates to a motor vehicle, and in particular a vehicle body structure for a motor vehicle, with an extended roof reinforcement structure. An example vehicle includes an A-pillar, a roof side rail, a dash panel, and a reinforcement structure extending at least partially through the roof side rail and the A-pillar to a front end forward of the dash panel.

Abstract: This disclosure details multi-purpose brackets for mounting accessory devices within vehicle cargo spaces. Exemplary multi-purpose brackets include a doubling flange, a first opening formed through the doubling flange, and a second opening formed through another location of the bracket. A first accessory device may be mounted within the first opening, and a second accessory device may be mounted within the second opening. The multi-purpose bracket may be formed in a stamping process that involves folding and clinching the doubling flange to a platform of the bracket.

Abstract: This disclosure relates to a motor vehicle, and in particular a vehicle body structure for a motor vehicle, with an extended roof reinforcement structure. An example vehicle includes an A-pillar, a roof side rail, a dash panel, and a reinforcement structure extending at least partially through the roof side rail and the A-pillar to a front end forward of the dash panel.

Abstract: This disclosure relates to a motor vehicle, and in particular a vehicle body structure for a motor vehicle, with an extended roof reinforcement structure. An example vehicle includes an A-pillar, a roof side rail, a dash panel, and a reinforcement structure extending at least partially through the roof side rail and the A-pillar to a front end forward of the dash panel.

Abstract: This disclosure relates to a motor vehicle, and in particular a vehicle body structure for a motor vehicle, with an extended roof reinforcement structure. An example vehicle includes an A-pillar, a roof side rail, a dash panel, and a reinforcement structure extending at least partially through the roof side rail and the A-pillar to a front end forward of the dash panel.

Abstract: This disclosure details multi-purpose brackets for mounting accessory devices within vehicle cargo spaces. Exemplary multi-purpose brackets include a doubling flange, a first opening formed through the doubling flange, and a second opening formed through another location of the bracket. A first accessory device may be mounted within the first opening, and a second accessory device may be mounted within the second opening. The multi-purpose bracket may be formed in a stamping process that involves folding and clinching the doubling flange to a platform of the bracket.

Abstract: A glass run mounting assembly (“mounting assembly”) for a vehicle door. The mounting assembly includes an elongated stepped bracket and an elongated plate attached to the bracket. The plate and the bracket define a channel with a glass run retention member therein. The plate has an outer surface, an inner surface, and a wall thickness therebetween. The outer surface of the plate has an appliqué thereto. The elongated plate offsets the appliqué from the glass pane substantially by one of wall thickness of the elongated plate.

Abstract: A vehicle display includes a base and a platform. A bearing between the base and the platform mounts the platform on the base for rotation about an upright axis. A rotator drive is provided for rotating the platform on the base. The apparatus also includes a base mounting column mounting the base on the ground. The column includes a lifting device for varying the height of the column between a lowered position with the platform substantially at ground level and a raised position with the platform positioned above ground level. With the column lowered, a vehicle may be driven onto the platform, tied down as necessary, lifted to the raised position and rotated for display purposes. This provides a simple drive on-drive off display that is visually very effective, easy to use and unobtrusive when not in use.

Abstract: Methods and apparatus for enabling internal circuitry associated with a device to be efficiently replaced in an operating environment for the device are disclosed. According to one aspect of the present invention, a device includes an enclosure that defines an interior of the device, and a circuit arrangement that is located in the interior. A data port interface is located in the interior, and the device also includes a receptacle and a protection circuitry arrangement. The receptacle is coupled to the circuit arrangement, and the protection circuitry arrangement provides protection to the circuit arrangement. The protection circuitry arrangement has an interface that is removably coupled to the receptacle such that at least a portion of the protection circuitry arrangement is contained in the interior of the device.

Abstract: In one embodiment, an apparatus includes at least one signal contact, a housing, and a discharge circuit arrangement. The housing defines a receptacle configured to receive a part of a cable assembly. The signal contact is disposed within the receptacle, and is configured to contact a first contact of the cable assembly when the cable assembly is received in the receptacle such that a signal may pass between the at least one signal contact and the first contact. The discharge circuit arrangement is at least partially disposed on the housing, and includes at least one discharge conductor that contacts the first contact and discharges an electrical charge associated with the first contact through a discharge circuit before the first contact contacts the signal contact.

Abstract: Methods and apparatus for providing a switch that includes multiple parts, and is arranged to function after extended periods of being in a depressed state are disclosed. In one embodiment, a multi-part switch includes a first contact, a second contact, and a plate. The first contact is electrically coupled to a first lead on a circuit board, and a second contact is electrically coupled to a second lead on the circuit board. The plate includes an electrically conductive area that contacts the first contact and the second contact to allow a signal to flow from the first contact to the second contact through the plate. In contacting the first contact and the second contact, the plate applies a compressive force to the first contact and to the second contact.

Abstract: Methods and apparatus for providing a switch that includes multiple parts, and is arranged to function after extended periods of being in a depressed state are disclosed. In one embodiment, a multi-part switch includes a first contact, a second contact, and a plate. The first contact is electrically coupled to a first lead on a circuit board, and a second contact is electrically coupled to a second lead on the circuit board. The plate includes an electrically conductive area that contacts the first contact and the second contact to allow a signal to flow from the first contact to the second contact through the plate. In contacting the first contact and the second contact, the plate applies a compressive force to the first contact and to the second contact.

Abstract: Methods and apparatus for discharging cables that are to be coupled to a connector are disclosed. According to one aspect of the present invention, an apparatus includes at least one signal contact, a housing, and a ground arrangement. The housing defines a receptacle configured to receive a part of a cable assembly. The signal contact is disposed within the receptacle, and is configured to contact a first contact of the cable assembly when the cable assembly is received in the receptacle such that a signal may pass between the signal contact and the first contact. The ground arrangement is at least partially disposed on the housing, and is arranged to contact and to ground the first contact before the first contact contacts the at least one signal contact.

Abstract: Methods and apparatus for discharging cables that are to be coupled to a connector are disclosed. According to one aspect of the present invention, an apparatus includes at least one signal contact, a housing, and a ground arrangement. The housing defines a receptacle configured to receive a part of a cable assembly. The signal contact is disposed within the receptacle, and is configured to contact a first contact of the cable assembly when the cable assembly is received in the receptacle such that a signal may pass between the signal contact and the first contact. The ground arrangement is at least partially disposed on the housing, and is arranged to contact and to ground the first contact before the first contact contacts the at least one signal contact.

Abstract: A vehicle display includes a base and a platform. A bearing between the base and the platform mounts the platform on the base for rotation about an upright axis. A rotator drive is provided for rotating the platform on the base. The apparatus also includes a base mounting column mounting the base on the ground. The column includes a lifting device for varying the height of the column between a lowered position with the platform substantially at ground level and a raised position with the platform positioned above ground level. With the column lowered, a vehicle may be driven onto the platform, tied down as necessary, lifted to the raised position and rotated for display purposes. This provides a simple drive on-drive off display that is visually very effective, easy to use and unobtrusive when not in use.

Abstract: Methods and apparatus for enabling internal circuitry associated with a device to be efficiently replaced in an operating environment for the device are disclosed. According to one aspect of the present invention, a device includes an enclosure that defines an interior of the device, and a circuit arrangement that is located in the interior. A data port interface is located in the interior, and the device also includes a receptacle and a protection circuitry arrangement. The receptacle is coupled to the circuit arrangement, and the protection circuitry arrangement provides protection to the circuit arrangement. The protection circuitry arrangement has an interface that is removably coupled to the receptacle such that at least a portion of the protection circuitry arrangement is contained in the interior of the device.

Abstract: A door sash header for an automotive vehicle includes a glazing seal retainer, an external trim retention portion, and a multi-channel weatherstrip retention structure which utilizes upwardly and downwardly opening channels cooperating with the door sash to retain a weatherstrip upon the header without the need for additional fastening devices such as mechanical fasteners or adhesives.