Patents by Inventor Michael Samuels

Michael Samuels has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220306752
    Abstract: Provided herein are EphA2 antibodies. These EphA2 antibodies bind preferentially to tumor tissue than normal tissue and bind to EphA2. Such antibodies are used in methods of inducing an immune response and methods of inhibiting tumor cell growth. Additionally provided are methods of producing such antibodies.
    Type: Application
    Filed: March 4, 2022
    Publication date: September 29, 2022
    Inventors: Alexander SCHOLZ, Nikhil VAD, Michael Samuel WEISS, Anne YE, Danhui ZHANG, Iraz T. AYDIN, Maryam M. BHATTI, Sean CARROLL, Jessica FINN, Shuning GAI, Shaun M. LIPPOW, Amy MANNING-BOG, Philippe MARGUET
  • Patent number: 11236115
    Abstract: The present invention relates to solid forms of a substituted benzoxaborole compound, specifically crystalline forms of a compound of formula I, compositions comprising crystalline forms of the compound of formula (I), and methods of their use.
    Type: Grant
    Filed: August 19, 2019
    Date of Patent: February 1, 2022
    Assignee: 5Metis, Inc.
    Inventors: Chun Yu Liu, Marissa Caroline Aubrey, Yong-Kang Zhang, Michael Samuels
  • Patent number: 11193176
    Abstract: The invention includes methods for determining the presence of a latent viral population by analyzing an RNA population from the virus with digital techniques, such as digital PCR or by sequencing cDNA produced from the RNA. The invention additional includes methods for determining the presence of latent viral populations by detecting and/or quantifying enzymes that are uniquely associated with the virus, e.g., reverse transcriptases.
    Type: Grant
    Filed: December 31, 2014
    Date of Patent: December 7, 2021
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Michael Samuels, Darren R. Link, Sirshendu Roopom Banerjee
  • Publication number: 20210221827
    Abstract: The present invention relates to solid forms of a substituted benzoxaborole compound, specifically crystalline forms of a compound of formula I, compositions comprising crystalline forms of the compound of formula (I), and methods of their use.
    Type: Application
    Filed: January 15, 2021
    Publication date: July 22, 2021
    Inventors: Chun Yu LIU, Marissa Caroline AUBREY, Yong-Kang ZHANG, Michael SAMUELS
  • Patent number: 11066424
    Abstract: The present invention relates to solid forms of a substituted benzoxaborole compound, specifically crystalline forms of a compound of formula I, compositions comprising crystalline forms of the compound of formula (I), and methods of their use.
    Type: Grant
    Filed: March 23, 2020
    Date of Patent: July 20, 2021
    Assignee: Boragen, Inc.
    Inventors: Chun Yu Liu, Marissa Caroline Aubrey, Yong-Kang Zhang, Michael Samuels
  • Publication number: 20200385409
    Abstract: A benzoxaborole formulation composition including a benzoxaborole, a non-ionic surfactant, or a non-ionic and ionic surfactant mixture, and a carrier is described herein. At least one of the non-ionic surfactant, the non-ionic and ionic surfactant mixture, and the carrier comprise a Lewis base or a N—H or O—H bond. The carrier is a solid or a liquid. Benzoxaborole compounds and methods of using the compounds and formulations of the compounds are described. For example, a method for reducing, preventing, ameliorating, or inhibiting an infestation by a pathogen by applying a compound or a formulation of a compound, wherein the pathogen is selected from insects, nematodes, bacteria, microbes, fungi, protozoa, viruses, and parasites, or any combinations thereof is described.
    Type: Application
    Filed: November 30, 2018
    Publication date: December 10, 2020
    Inventors: Marissa AUBREY, Chun Yu LIU, Chunliang LIU, Michael SAMUELS, Yong-Kang ZHANG, Yasheen ZHOU
  • Publication number: 20200239497
    Abstract: The present invention relates to solid forms of a substituted benzoxaborole compound, specifically crystalline forms of a compound of formula I, compositions comprising crystalline forms of the compound of formula (I), and methods of their use.
    Type: Application
    Filed: March 23, 2020
    Publication date: July 30, 2020
    Inventors: Chun Yu LIU, Marissa Caroline AUBREY, Yong-Kang ZHANG, Michael SAMUELS
  • Patent number: 10724082
    Abstract: The invention generally relates to methods for increasing the amount of DNA available for analysis when using partitioned samples and parallel processing. For example, double-stranded DNA can be dissociated into two single-stranded components, and the single strands partitioned into different droplets prior to analysis. The disclosed methods are useful for performing digital PCR analysis on samples where the target DNA is not in abundance, for example when the sample originates from a body fluid or an FFPE sample.
    Type: Grant
    Filed: December 8, 2017
    Date of Patent: July 28, 2020
    Assignee: Bio-Rad Laboratories, Inc.
    Inventor: Michael Samuels
  • Publication number: 20200055878
    Abstract: The present invention relates to solid forms of a substituted benzoxaborole compound, specifically crystalline forms of a compound of formula I, compositions comprising crystalline forms of the compound of formula (I), and methods of their use.
    Type: Application
    Filed: August 19, 2019
    Publication date: February 20, 2020
    Inventors: Chun Yu LIU, Marissa Caroline AUBREY, Yong-Kang ZHANG, Michael SAMUELS
  • Publication number: 20190180393
    Abstract: Automated listing and pricing management of real estate property is disclosed. Specifically, systems and methods to efficiently list property and to providing listing information to customer via mobile applications are disclosed. To optimize the listing retrieval experience from the client perspective, renter qualifications are provided to a customer prior to a time investment in the bidding process. From the proprietor's perspective, dynamic pricing recommendations are generated to optimize profit and minimize vacancies. Tools are further disclosed to management multiple properties and to provide analytics reporting.
    Type: Application
    Filed: December 13, 2017
    Publication date: June 13, 2019
    Inventors: Edward Alexander Kelly, Michael Samuel Steuer
  • Publication number: 20180257922
    Abstract: A system for dispensing beverage, particularly cask ale, the system comprising: a pump configured for drawing cask ale by suction from a supply into a pump inlet and delivering cask ale from a pump outlet under sustained pressure; a flow regulator having an inlet for receiving cask ale under sustained pressure from the pump outlet, and a flow regulator outlet for delivering cask ale under a dispense pressure; and a dispense conduit for receiving cask ale under dispense pressure from the flow regulator outlet and turbulating and dispensing cask ale via the dispense outlet. Dispense methods and a valve nozzle are also described.
    Type: Application
    Filed: March 5, 2018
    Publication date: September 13, 2018
    Inventors: Michael Samuel Thomas Watts, Ian Tinsley Frost, Michael Anthony Flavin, Leon Antony Farrel, Philip Anthony Atkinson
  • Patent number: 9967867
    Abstract: A method in a network node comprises providing to a user equipment a dedicated physical control channel (DPCCH), the DPCCH having an associated first fractional dedicated physical channel (F-DPCH) for conveying transmit power control commands to the user equipment for power controlling the DPCCH, and providing to the user equipment a secondary dedicated physical control channel (S-DPCCH), the S-DPCCH comprising an uplink control channel for communicating transmit power control commands, the S-DPCCH having an associated second F-DPCH for conveying transmit power control commands to the user equipment for power controlling the S-DPCCH. The method comprises receiving, from the user equipment, a downlink transmit power control command, the downlink transmit power control command carried on the S-DPCCH; and controlling a transmit power of the second F-DPCH associated with the S-DPCCH based on the downlink transmit power control command carried on the S-DPCCH.
    Type: Grant
    Filed: February 28, 2017
    Date of Patent: May 8, 2018
    Assignee: TELEFONAKTIEBOLAGET LM ERICSSON (PUBL)
    Inventors: Yi-Pin Eric Wang, Erik Larsson, Michael Samuel Bebawy, Zhang Zhang, Peter von Wrycza
  • Patent number: 9944977
    Abstract: The invention generally relates to methods for distinguishing a rare genetic variation in a nucleic acid sequence.
    Type: Grant
    Filed: December 12, 2014
    Date of Patent: April 17, 2018
    Assignee: Raindance Technologies, Inc.
    Inventors: Darren R. Link, Michael Samuels
  • Publication number: 20180100185
    Abstract: The invention generally relates to methods for increasing the amount of DNA available for analysis when using partitioned samples and parallel processing. For example, double-stranded DNA can be dissociated into two single-stranded components, and the single strands partitioned into different droplets prior to analysis. The disclosed methods are useful for performing digital PCR analysis on samples where the target DNA is not in abundance, for example when the sample originates from a body fluid or an FFPE sample.
    Type: Application
    Filed: December 8, 2017
    Publication date: April 12, 2018
    Inventor: Michael Samuels
  • Patent number: 9930622
    Abstract: A network node of a wireless communication network serves a wireless device that is transmitting one or more uplink channels to each of a serving cell and at least one non-serving cell. Inner-loop power control, ILPC, commands are sent (420) to the wireless device in such a way that only ILPC commands transmitted by the serving cell affect the power of one or more control channels transmitted by the wireless device to the serving cell. In addition, a power offset for a data channel transmitted by the wireless device to the at least one non-serving cell is adjusted (430), so as to compensate for an uplink-downlink power imbalance among the serving cell and the at least one non-serving cell.
    Type: Grant
    Filed: May 9, 2014
    Date of Patent: March 27, 2018
    Assignee: Telefonaktiebolaget LM Ericsson (publ)
    Inventors: Erik Larsson, Michael Samuel Bebawy, Peter Von Wrycza, Eric Wang YP
  • Patent number: 9840734
    Abstract: The invention generally relates to methods for increasing the amount of DNA available for analysis when using partitioned samples and parallel processing. For example, double-stranded DNA can be dissociated into two single-stranded components, and the single strands partitioned into different droplets prior to analysis. The disclosed methods are useful for performing digital PCR analysis on samples where the target DNA is not in abundance, for example when the sample originates from a body fluid or an FFPE sample.
    Type: Grant
    Filed: October 21, 2013
    Date of Patent: December 12, 2017
    Assignee: Raindance Technologies, Inc.
    Inventor: Michael Samuels
  • Patent number: 9756591
    Abstract: A method for synchronization in a network node is disclosed. The method comprises determining an N-symbol slice of a received signal, the N-symbol slice corresponding to a sync point hypothesis, dividing the N-symbol slice into one or more segments, each of the one or more segments having the same symbol length, and determining one or more phase rotation operators for each of the one or more segments, the determined one or more phase rotation operators compensating for a phase rotation introduced by an initial frequency error. The method further comprises performing coherent correlation within each of the one or more segments using the determined one or more phase rotation operators, and performing differentially coherent correlation on each of the one or more segments.
    Type: Grant
    Filed: March 19, 2015
    Date of Patent: September 5, 2017
    Assignee: Telefonaktiebolaget LM Ericsson (publ)
    Inventors: Yi-Pin Eric Wang, Bo Hagerman, Ali S. Khayrallah, Michael Samuel Bebawy, Leif Wilhelmsson
  • Patent number: 9743413
    Abstract: A method in a network node for enhancing a channel estimate based on a Dedicated Physical Control Channel, DPCCH, between a user node and the network node is provided. The DPCCH has a first power. The network node receives (501) the DPCCH. The first power of the DPCCH is boosted with additional power, resulting in a second power. The network node then obtains (502) a channel estimate based on the DPCCH comprising the second power. As soon as said channel estimate is obtained, the network node removes (503) the additional power from the DPCCH based channel estimate.
    Type: Grant
    Filed: November 16, 2015
    Date of Patent: August 22, 2017
    Assignee: Telefonatiebolaget LM Ericsson (Publ)
    Inventors: Erik Larsson, Michael Samuel Bebawy, Peter Von Wrycza, Yi-Pin Eric Wang
  • Publication number: 20170171858
    Abstract: A method in a network node comprises providing to a user equipment a dedicated physical control channel (DPCCH), the DPCCH having an associated first fractional dedicated physical channel (F-DPCH) for conveying transmit power control commands to the user equipment for power controlling the DPCCH, and providing to the user equipment a secondary dedicated physical control channel (S-DPCCH), the S-DPCCH comprising an uplink control channel for communicating transmit power control commands, the S-DPCCH having an associated second F-DPCH for conveying transmit power control commands to the user equipment for power controlling the S-DPCCH. The method comprises receiving, from the user equipment, a downlink transmit power control command, the downlink transmit power control command carried on the S-DPCCH; and controlling a transmit power of the second F-DPCH associated with the S-DPCCH based on the downlink transmit power control command carried on the S-DPCCH.
    Type: Application
    Filed: February 28, 2017
    Publication date: June 15, 2017
    Inventors: Yi-Pin Eric Wang, Erik Larsson, Michael Samuel Bebawy, Zhang Zhang, Peter von Wrycza
  • Patent number: 9667274
    Abstract: A method in a network node comprises generating a parity-check matrix for decoding a transmission scheme. The transmission scheme comprises a repetition code, an interleaver, and a modulation having a memory property. The parity-check matrix comprises a function of: a differentiator matrix, the differentiator matrix comprising an inverse of an accumulator matrix; a deinterleaver matrix, the deinterleaver matrix comprising an inverse of an interleaver matrix, the interleaver matrix comprising a square unitary permutation matrix for introducing randomness; and a repetition decoder matrix.
    Type: Grant
    Filed: March 19, 2015
    Date of Patent: May 30, 2017
    Assignee: Telefonaktiebolaget LM Ericsson (publ)
    Inventors: Yi-Pin Eric Wang, Bo Hagerman, Ali S. Khayrallah, Michael Samuel Bebawy, Leif Wilhelmsson