Abstract: The invention relates to a method for preparing an antibody-producing cell line capable of directed constitutive hypermutation of a specific nucleic acid region, comprising the steps of: a) screening a clonal cell population for V gene diversity; b) isolating one or more cells which display V gene diversity and comparing the rate of accumulation of mutations in the V genes and other genes of the selected cells; and c) selecting a cell in which the rate of V gene mutation exceeds that of other gene mutation.

Abstract: An adapter assembly including a base for supporting a SINCGARS radio and a radio frequency power amplifier, a first connector for electrically connecting with the SINCGARS radio and a second connector for electrically connecting with the power amplifier, a first power supply electrically connected with the first connector and a second power supply and a third power supply, the second power supply and the third power supply each being electrically connected with the second connector.

Abstract: A process for the production of polymers in which an oligomeric precursor is formed first in a melt phase. A phase transition is then induced in the polymerizing reaction medium under the action of shear in such a way that the simultaneous action of the shear, and the ongoing polymerization through the phase transition produces a product that is in a powdered form.

Abstract: The invention relates to a method for preparing an antibody-producing cell line capable of directed constitutive hypermutation of a specific nucleic acid region, comprising the steps of: a) screening a clonal cell population for V gene diversity; b) isolating one or more cells which display V gene diversity and comparing the rate of accumulation of mutations in the V genes and other genes of the selected cells; and c) selecting a cell in which the rate of V gene mutation exceeds that of other gene mutation.

Abstract: Ovenware for microwave ovens which contain a composition comprising a susceptor and a thermoplastic or thermoset polymer are improved when the composition also has a thermal conductivity of about 0.7 W/m° K. or more. Heat generated by absorption of microwave radiation by the susceptor is more readily conducted to the food being cooked when the thermal conductivity of the composition is high, particularly when the part containing the susceptor is relatively thick. Also described are designs for various pieces of ovenware containing this composition.

Abstract: A flame retardant fabric comprising bicomponent fibers having a sheath and a core wherein the sheath comprises a fully aromatic thermoplastic polymer with a Limited Oxygen Index of at least 26 and the core comprises a thermoplastic polymer.

Abstract: A sheet comprising thermoplastic polymer (TP) and short high tensile modulus fibers, in which the concentration of TP in the middle of the sheet is higher than at the surface of the sheet, useful for making prepregs with a thermoset resin.

Abstract: This invention relates to a device for providing temporary support to a structure such as a formwork member. The invention includes a support device (1) for supporting a formwork member (16) adjacent to formwork surface. A securing means (12) is associated with the structure being operable for securing the support device to the formwork surface. A switching means (3) is provided for switching the securing means (12) between an operating condition whereby the securing means (12) secures the support device to the formwork surface, and a non operating condition whereby the securing means (12) is not securing the support device to the formwork surface. Advantageously, the support device (1) can be easily and predictably activated and de-activated.

Abstract: Virtual concatenation circuitry is disclosed which provides stall need detection and an associated stall mechanism in a network element of a data communication network. The virtual concatenation circuitry in a preferred embodiment is operative to provide differential delay compensation for one or more member streams of a virtual concatenation stream. The differential delay compensation involves introducing delay into at least one of the member streams. The stall need detection aspect of the invention relates to detecting a condition under which introduction of the delay is required for alignment of member streams, for example, upon addition of a member stream to the virtual concatenation stream. Such a condition may arise, for example, if a transmission delay of an added stream is larger than that of all other member streams of the virtual concatenation stream.

Abstract: A process for the production of a chimeric antibody, comprising: a) preparing a replicable expression vector including a suitable promoter operably linked to a DNA sequence comprising a first part which encodes at least the variable region of the heavy or light chain of an Ig molecule and a second part which encodes at least part of a second protein; b) if necessary, preparing a replicable expression vector incuding a suitable promoter operably linked to a DNA sequence which encodes at least the variable region of a complementary light or heavy chain respectively of an Ig molecule; c) transforming an immortalized mammalian cell line with the or both prepared vectors; and d) culturing said transformed cell line to produce the chimeric antibody; chimeric antibodies produced by this process; and plasmids and transformed cell lines used in the process.

Abstract: A power supply station is presented having a substantially flat-based portion and a taller rear portion extending upward from the rear of the primary base portion, but being formed integrally therefrom. Dual connectors extend forward from the front surface of the rear portion and are adapted for connecting with recessed male connectors found on the rear sockets of SINCGARS radio. Internal electronics within a unit converts standard 110/220 Volt AC current into a standard +12 Volt DC source compatible with standard SINCGARS radios. The internal electronics provide separate conversion power supplies for both connectors to allow for two SINCGARS radios to be powered simultaneously. The invention also includes switches for controlling the powering of any installed SINCGARS radio as well as low friction runners and retention latches on the front of the unit to allow for secure retention of the SINCGARS radio on the invention while powering.

Abstract: The invention relates to a method for preparing an antibody-producing cell line capable of directed constitutive hypermutation of a specific nucleic acid region, comprising the steps of: a) screening a clonal cell population for V gene diversity; b) isolating one or more cells which display V gene diversity and comparing the rate of accumulation of mutations in the V genes and other genes of the selected cells; and c) selecting a cell in which the rate of V gene mutation exceeds that of other gene mutation.

Abstract: The present invention relates to a method for generating diversity in a gene or gene product by exploiting the natural somatic hypermutation capability of antibody-producing cells, as well as cell lines capable of generating diversity in defined gene products. More specifically, the invention relates to methods of preparing a lymphoid cell line capable of directed constitutive hypermutation of a target nucleic acid region, comprising screening a cell population for ongoing target sequence diversification, and selecting a cell in which the rate of target nucleic acid mutation exceeds that of other nucleic acid mutation by a factor of 100 or more.

Abstract: The invention relates to a method for preparing an antibody-producing cell line capable of directed constitutive hypermutation of a specific nucleic acid region, comprising the steps of: a) screening a clonal cell population for V gene diversity; b)isolating one or more cells which display V gene diversity and comparing the rate of accumulation of mutations in the V genes and other genes of the selected cells; and c) selecting a cell in which the rate of V gene mutation exceeds that of other gene mutations.

Abstract: A method of lattice-quantizing an eight-long data point to minimize storage requirements by acquiring the data point, multiplying each coordinate of the data point by {square root over (2)} to form an inflated data point, rounding each coordinate of the rounded and inflated data point to the nearest integer, modulo-two reducing each coordinate of the rounded and inflated data point to form an initial codeword, multiplying a parity-check matrix of an eight-bit Extended Hamming Code by the result of the last step to form a syndrome, correcting any single-bit errors and double-bit errors, if any, in the initial codeword and the rounded and inflated data point, transforming the coordinate system of the initial codeword to an extended quadratic residue form, creating a signal packet, and transmitting the signal packet to a receiver.

Abstract: A method of lattice quantizing a 24-long data point to minimize storage requirements by acquiring the data point, multiplying each coordinate of the data point by the square root of 8 to form an inflated data point, finding the closest point of the inflated Leech lattice by any method, creating a signal packet, and transmitting the packet to a receiver.

Abstract: Antibodies which recognize a tumor related antigen designated CA55.1 such as hybridoma 55.1 deposited as ECACC deposit no. 93081901 in which the complementarity determining regions have the following sequences:a) heavy chainCDR1 G Y W I H (SEQ ID NO: 27)CDR2 E V N P S T G R S D Y N E K F K N (SEQ ID NO: 28)CDR3 E R A Y G Y D D A M D Y (SEQ ID NO: 29)b) light chainCDR1 K S S Q S L L N S R T R K N Y L A (SEQ ID NO: 30)CDR2 W A S T R T S (SEQ ID NO: 31)CDR3 K Q S Y T L R T (SEQ ID NO: 32)or a conservative analogue thereof. The peptide ACEHRGSGWC (SEQ ID NO: 26), as displayed on the surface of bacteriophage NCIMB No. 40638, is a mimic of the tumor related antigen CA55.1.

Abstract: A convertible wheeled vehicle which is capable of assembly into any one of a plurality of different vehicles includes a front wheel frame assembly. A wheel is mounted to the front wheel frame assembly. A chassis assembly has at least one wheel. A pair of vertically spaced plates extends from the front wheel assembly and a tubular connector associated with the chassis assembly is disposed therebetween. A pin extends between the plates and through the tubular connector for securing the chassis in any one of a plurality of orientations.

Abstract: A registration mechanism for feeding sheets seriatim including a plurality of continuously driven roller sets located along a sheet feed path. A first roller set receives the sheets seriatim and moves the sheets toward a second roller set. The second roller set includes a pair of axially spaced, continuously driven rollers mounted on a drive shaft and a pair of thrust washers which sandwich a registration disc therebetween, the disc being freely mounted on the roller drive shaft. The registration disc has a registration finger which selectively extends through the sheet feed path. When the finger is positioned to extend through the feed path, it is latched to prevent rotation of the disc and provide registration of the sheets fed by the first roller set against the finger.