Patents by Inventor Michael Simons

Michael Simons has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090225872
    Abstract: Systems, methods, apparatus and computer program products are provided for signaling to a receiver an availability of a service and a deterministic mapping of a service content corresponding to the service. A modulator receives a digital signal and generates a data frame from the digital signal, where the data frame is divided into segments, where at least one grouping of the segments contains the service content. The modulator modulates at least one grouping in accordance with the deterministic mapping. A receiving device receives a digital signal containing the availability of a service, the deterministic mapping corresponding to the service, and the service content, and performs an operation on the service content in accordance with the deterministic mapping.
    Type: Application
    Filed: April 3, 2009
    Publication date: September 10, 2009
    Applicant: ROHDE & SCHWARZ GMBH & CO. KG
    Inventor: Michael Simon
  • Publication number: 20090193487
    Abstract: Systems, methods, apparatus and computer program products are provided for signaling to a receiver an availability of a service and a deterministic mapping of a service content corresponding to the service. A modulator receives a digital signal and generates a data frame from the digital signal, where the data frame is divided into segments, where at least one grouping of the segments contains the service content. The modulator modulates at least one grouping in accordance with the deterministic mapping. A receiving device receives a digital signal containing the availability of a service, the deterministic mapping corresponding to the service, and the service content, and performs an operation on the service content in accordance with the deterministic mapping.
    Type: Application
    Filed: April 3, 2009
    Publication date: July 30, 2009
    Applicant: ROHDE & SCHWARZ GMBH & CO. KG
    Inventor: Michael Simon
  • Publication number: 20090176249
    Abstract: The present invention relates to a method of detecting collateral artery formation by measuring the level of NT-pro-BNP or BNP in an individual.
    Type: Application
    Filed: March 12, 2009
    Publication date: July 9, 2009
    Inventors: Kiang-Tech Jerry Yeo, Michael Simons
  • Patent number: 7532857
    Abstract: Systems, methods, apparatus are provided for providing to a receiver a time diverse digital signal corresponding to a service including receiving a digital signal containing a service content and receiving a digital signal containing a non-deterministic content. The service content is inserted into a first predetermined number of data packets in a first predetermined number of data frames deterministically. In addition, a first portion of the non-deterministic content is inserted into a second predetermined number of data packets in the first predetermined number of data frames. A copy of the first predetermined number of data packets is generated. The first predetermined number of data frames is broadcast over a distribution network. The copy of the first predetermined number of data packets is inserted into a second predetermined number of data frames and a second portion of the non-deterministic content is inserted into the second predetermined number of data frames.
    Type: Grant
    Filed: June 7, 2006
    Date of Patent: May 12, 2009
    Assignee: Rohde & Schwarz GmbH & Co. KG
    Inventor: Michael Simon
  • Patent number: 7532677
    Abstract: A system, method, apparatus and computer code are provided for producing coherent symbols from digital RF transmitters. A receiver receives a first initialization packet containing a plurality of stuff bytes and Trellis coders are deterministically initialized using the first initialization packet.
    Type: Grant
    Filed: February 28, 2006
    Date of Patent: May 12, 2009
    Assignee: Rohde & Schwarz GmbH & Co., KG
    Inventor: Michael Simon
  • Publication number: 20090068736
    Abstract: The present invention relates to mutant proline-and-arginine rich (PR) peptides with defined structural characteristics for use in inhibiting mammalian 20S proteasome activity and modulating expression of genes regulating the NF-?B pathway. Mutant PR peptides of the present invention differ from wild-type PR peptides by having at least one to three amino acid substitutions, wherein at least one of the amino acid residues at position one, two or three of the mutant PR peptide is positively charged.
    Type: Application
    Filed: February 12, 2007
    Publication date: March 12, 2009
    Inventors: Sudha Veeraraghavan, Michael Simons
  • Publication number: 20080211969
    Abstract: Systems, apparatus, methods and computer program products are provided for causing a dataframe to be emitted at an air interface of an antenna. A memory stores a transmission to antenna delay value (TAD). An offset calculator calculates an offset value based on an epoch of a global timebase generator and the transmission to antenna delay value (TAD). An interface controller in communication with the offset calculator communicates a segment synchronization signal and a field synchronization signal based on the offset value.
    Type: Application
    Filed: February 1, 2008
    Publication date: September 4, 2008
    Applicants: ROHDE & SCHWARZ GMBH & CO. KG, ROSUM CORPORATION
    Inventors: MICHAEL SIMON, JAMES SPILKER, SCOTT FURMAN
  • Publication number: 20080190809
    Abstract: A package for flat, pliable objects, such as for wafer-shaped or film-shaped drug forms. The package has a carrier layer, a cover layer which is detachably connected to the carrier layer, and a first surface region wherein the carrier layer is not connected to the cover layer and is completely surrounded by a margin area. A cavity, enclosed on all sides, is formed for accommodating an object. The package has a second surface region wherein the carrier layer is not connected to the cover layer. At least one perforation line extends at least partially within the second surface region, and is provided both in the carrier layer and in the cover layer. Severing the perforation line forms a free edge of the cover layer which serves as a gripping aid and enables manual removal of the cover layer from the carrier layer. The disclosure further covers a process for packaging flat, pliable objects by forming the above-described package.
    Type: Application
    Filed: September 10, 2005
    Publication date: August 14, 2008
    Inventors: Michael Simon, Markus Krumme, Karin Ludwig, Bodo Asmussen
  • Publication number: 20080117301
    Abstract: A real time apparatus for testing a DTV antenna transmitting system, wherein the DTV antenna transmitting system transmits an original signal from a DTV transmitter to a DTV transmitting antenna, is disclosed that includes a probe, wherein the probe is connected in series with the DTV antenna transmitting system, and senses signals traversing the DTV antenna transmitting system. An error detector of the testing apparatus compares the received signal to the original signal to identify the magnitude and location of errors.
    Type: Application
    Filed: October 31, 2007
    Publication date: May 22, 2008
    Inventors: Michael Simon, Andre J. Skalina
  • Patent number: 7345021
    Abstract: The present invention provides both a method and means for regulating angiogenesis within living cells, tissues, and organs in-situ. The regulation is performed using native PR-39 peptide or one of its shorter-length homolog, for interaction with such proteasomes as one present in the cytoplasm of viable cells. The result of PR-39 peptide interaction with proteasomes is a decrease in the intracellular degradation of active peptides such as HIF-1? and a consequential stimulation of angiogenesis in-situ.
    Type: Grant
    Filed: October 25, 1999
    Date of Patent: March 18, 2008
    Assignee: Beth Israel Deaconess Medical Center
    Inventors: Michael Simons, Youche Gao
  • Patent number: 7317040
    Abstract: A compound of formula (I): namely (2S)-2-amino-4-{[2-(ethanimidoylamino)ethyl]thio}butanoic acid, compound with phosphoric acid, or a solvate or physiologically functional derivative thereof, is useful as a relatively non-hygroscopic selective inhibitor of inducible nitric oxide synthase.
    Type: Grant
    Filed: December 17, 2001
    Date of Patent: January 8, 2008
    Assignee: SmithKline Beecham Corporation
    Inventors: David Box, David Colclough, Iain Gillies, Michael Simon Loft, Rebecca Moore
  • Publication number: 20070223612
    Abstract: A system, method, apparatus and computer code are provided for producing coherent symbols from digital RF transmitters. A receiver receives a first initialization packet containing a plurality of stuff bytes and Trellis coders are deterministically initialized using the first initialization packet.
    Type: Application
    Filed: February 28, 2006
    Publication date: September 27, 2007
    Applicant: Rohde & Schwarz, Inc.
    Inventor: Michael Simon
  • Publication number: 20070136083
    Abstract: Provided is a method for disabling a motor vehicle when a user of the motor vehicle fails to complete a specific task, such as making a loan or lease payment. The method comprises first determining a payment due deadline and forwarding a signal on a two-way communication system a predetermined number of days prior to the due date to initiate a reminder system in the vehicle that the payment is coming due. A return signal is sent to the provider of the first signal that the first signal was received and the reminder system activated. Once it is determined that the due date has passed and payment has still not been made, another signal is sent which disables the vehicle. A return signal, if desired, can again be sent to the provider that the first signal for disabling the vehicle was safely received, and that the vehicle was disabled. A keypad is also provided in the system for entering an emergency code to enable the motor vehicle for a predetermined period of time whenever the vehicle has been disabled.
    Type: Application
    Filed: February 10, 2006
    Publication date: June 14, 2007
    Inventors: Michael Simon, Franklin Simon
  • Patent number: 7202212
    Abstract: The present invention provides both a method and means for regulating I?B? degradation, NF?B activity, and NF?B-dependent gene expression within living cells, tissues, and organs in-situ. The selective regulation is performed using native PR-39 peptide or one of its shorter-length homologs, for interaction with such I?B? and proteasomes as are present in the cytoplasm of viable cells. The result of PR-39 peptide interaction with I?B? is a selective alteration in the intracellular proteolytic activity of proteasomes, which in turn, causes a reduction of I?B?, a decrease of NF?B activity, and a down-regulation of NF?B-dependent gene expression.
    Type: Grant
    Filed: March 18, 2003
    Date of Patent: April 10, 2007
    Assignee: Beth Israel Deaconess Medical Center
    Inventors: Michael Simons, Youhe Gao
  • Patent number: 7202217
    Abstract: The present invention provides both a method and means for regulating angiogenesis within living cells, tissues, and organs in-situ. The regulation is performed using native PR-39 peptide or one of its shorter-length homologs, for direct interaction with the ?7 subunit of such proteasomes as one present in the cytoplasm of viable cells. The result of PR-39 peptide interaction with proteasomes is a decrease in the intracellular degradation of active peptides such as HIF-1? and a consequential stimulation of angiogenesis in-situ.
    Type: Grant
    Filed: March 26, 1999
    Date of Patent: April 10, 2007
    Assignee: Beth Israel Deacones Medical Center
    Inventors: Michael Simons, Youhe Gao
  • Publication number: 20070065804
    Abstract: The present invention provides both a method and means for regulating I?B? degradation, NF?B activity, and NF?B-dependent gene expression within living cells, tissues, and organs in-situ. The selective regulation is performed using native PR-39 peptide or one of its shorter-length homologs, for interaction with such I?B? and proteasomes as are present in the cytoplasm of viable cells. The result of PR-39 peptide interaction with I?B? is a selective alteration in the intracellular proteolytic activity of proteasomes, which in turn, causes a reduction of I?B?, a decrease of NF?B activity, and a down-regulation of NF?B-dependent expression.
    Type: Application
    Filed: July 18, 2006
    Publication date: March 22, 2007
    Inventors: Michael Simons, Youhe Gao
  • Patent number: 7169604
    Abstract: The present invention provides both a method and means for regulating I?B? degradation, NF?B activity, and NF?B-dependent gene expression within living cells, tissues, and organs in-situ. The selective regulation is performed using native PR-39 peptide or one of its shorter-length homologs, for interaction with such I?B? and proteasomes as are present in the cytoplasm of viable cells. The result of PR-39 peptide interaction with I?B? is a selective alteration in the intracellular proteolytic activity of proteasomes, which in turn, causes a reduction of I?B?, a decrease of NF?B activity, and a down-regulation of NF?B-dependent gene expression.
    Type: Grant
    Filed: December 29, 1999
    Date of Patent: January 30, 2007
    Assignee: Beth Israel Deaconess Medical Center
    Inventors: Michael Simons, Youhe Gao
  • Publication number: 20060245516
    Abstract: Systems, methods, apparatus and computer program products are provided for signaling a deterministic mapping corresponding to a service. The deterministic mapping is inserted within an in-band ATSC vestigial sideband broadcast signal or an out-of-band signal and transmitted to receivers capable of consuming the service.
    Type: Application
    Filed: April 20, 2006
    Publication date: November 2, 2006
    Applicant: Rohde & Schwarz, Inc.
    Inventor: Michael Simon
  • Publication number: 20060246836
    Abstract: Systems, methods, apparatus are provided for providing to a receiver a time diverse digital signal corresponding to a service including receiving a digital signal containing a service content and receiving a digital signal containing a non-deterministic content. The service content is inserted into a first predetermined number of data packets in a first predetermined number of data frames deterministically. In addition, a first portion of the non-deterministic content is inserted into a second predetermined number of data packets in the first predetermined number of data frames. A copy of the first predetermined number of data packets is generated. The first predetermined number of data frames is broadcast over a distribution network. The copy of the first predetermined number of data packets is inserted into a second predetermined number of data frames and a second portion of the non-deterministic content is inserted into the second predetermined number of data frames.
    Type: Application
    Filed: June 7, 2006
    Publication date: November 2, 2006
    Applicant: Rohde & Schwarz, Inc.
    Inventor: Michael Simon
  • Publication number: 20060244865
    Abstract: A system, method, apparatus and computer code for communicating a training sequence for initializing an equalizer in a digital receiver are provided including receiving a digital signal containing data to be broadcast from a digital RF transmitter and inserting the training sequence into the digital signal deterministically such that a predetermined sequence of symbols are communicated to the receiver.
    Type: Application
    Filed: May 25, 2006
    Publication date: November 2, 2006
    Applicant: Rohde & Schwarz, Inc.
    Inventor: Michael Simon