Abstract: A bifurcated stent comprises a first stent section and a second stent section. Each stent section is expandable from a predeployed state to a deployed state independently from one another. The second stent section having an end engaged to a receiving region of the first stent section. In the deployed state the first stent section defines a primary flow path and the second stent section defines a secondary flow path in fluid communication with the first flow path. At least a portion of one or both the first stent section and second stent section is constructed from a wire member.

Abstract: A steering column (10) includes a steering column member (12) rotatable to turn steerable vehicle wheels. A support tube (24) supports the steering column member (12) for rotation about a longitudinal axis (26) of the steering column member. The support tube (24) and the steering column member (12) extend between clamping members (32, 34) and are axially movable relative to the clamping members. The clamping members (32, 34) clamp the support tube (24) to prevent movement of the support tube and the steering column member (12) relative to the clamping members. A pivot shaft (38) pivotally connects the clamping members (32, 34) to a mounting bracket (42). A locking mechanism (78) presses the clamping members (32, 34) toward each other to clamp the support tube (24) to prevent axial movement of the support tube relative to the clamping members. The locking mechanism (18) also locks the clamping members (32, 34) in one of a plurality of pivot positions relative to the mounting bracket (42).

Abstract: Novel polymer-supported quenching reagents of Formula (I): P-L-Q, wherein P is a polymer of low chemical reactivity which is soluble or insoluble; Q is one or more quenching reagents, or an acid or base addition salts thereof, that are capable of selective covalent reaction with unwanted byproducts, or excess reagents; and L is one or more chemically robust linkers that join P and Q; are described, as well as methods for their preparation and methods for their use in the rapid purification of synthetic intermediates and products in organic synthesis, combinatorial chemistry and automated organic synthesis.

Abstract: A method for controlling deformation of an erected structural metal plate culvert or underpass during backfilling of the erected structure comprises: building progressively a reinforced earth retaining system on each side of the erected structure by alternately layering a plurality of compacted layers of earth with interposed layers of reinforcement to form reinforced earth on each side of the erected structure and securing to each side of the structure each said layer of reinforcement in the reinforced earth, whereby such securement of each said layer of reinforcement to said structure controls deformation of the erected structure during backfilling with the reinforced earth on each side of the structure. The layer of reinforcement may be a plurality of strips extending away from the structure, or a reinforcement mat of interconnected rods.

Abstract: Novel inhibitors of protein farnesyltransferase enzyme are described, as well as methods for the preparation and pharmaceutical compositions of the same, which are useful in controlling tissue proliferative diseases, including cancer and restenosis.

Abstract: The invention concerns a series of novel bis-urea derivatives, nonpeptides, which show good binding affinity for the CCK-B receptor. The compounds, compositions containing them, methods of preparation, and utilities including anxiety, gastric acid secretion inhibition, and psychoses are included.

Abstract: The present invention is novel compounds which are 3,5-di-tertiary-butyl-4-hydroxyphenyl substituted 1,2,4- and 1,3,4-thiadazoles and oxadiazoles, and 1,2,4-triazoles, and pharmaceutically acceptable additions and base salts thereof, pharmaceutical compositions and methods of use therefor. The invention compounds are now found to have activity as inhibitors of 5-lipoxygenase and/or cyclooxygenase providing treatment of conditions advantageously affected by such inhibition including inflammation, arthritis, pain, fever, and the like.

Abstract: A reinforced metal box culvert is provided which has the standard crown, opposing sides and opposite curved haunches. The culvert is characterized in having continuous corrugated metal sheet reinforcement secured to at least the crown of the culvert and extends the length of the culvert which is effective in supporting the load. The corrugated reinforcement has a profile which abuts the crown corrugations with the troughs of the reinforcement being secured to the crests of the corrugated crown. The corrugated reinforcement sheet has a curvature complementary to the corrugated crown to facilitate securement. The continuous reinforcement, as secured to the culvert in an uninterrupted manner, provides an optimum load carrying capacity for selected extent of reinforcement provided by the reinforcement metal sheets.

Abstract: The present invention is novel compounds which are 3,5-di-tertiary-butyl-4-hydroxyphenyl substituted 1,2,4- and 1,3,4-thiadazoles and oxadiazoles, and 1,2,4-triazoles, and pharmaceutically acceptable additions and base salts thereof, pharmaceutical compositions and methods of use therefor. The invention compounds are now found to have activity as inhibitors of 5-lipoxygenase and/or cyclooxygenase providing treatment of conditions advantageously affected by such inhibition including inflammation, arthritis, pain, fever, and the like.

Abstract: The present invention is novel compounds which are 3,5-di-tertiary-butyl-4-hydroxyphenyl substituted 1,2,4- and 1,3,4-thiadazoles and oxadiazoles, and 1,2,4-triazoles, and pharmaceutically acceptable additions and base salts thereof, pharmaceutical compositions and methods of use therefor. The invention compounds are now found to have activity as inhibitors of 5-lipoxygenase and/or cyclooxygenase providing treatment of conditions advantageously affected by such inhibition including inflammation, arthritis, pain, fever, and the like.

Abstract: This invention relates to novel compounds which are ACAT inhibitors rendering them useful in lowering blood cholesterol levels. The compounds contain two urea or thiourea, amide, or amine moieties or combinations of said moieties and have the following general formula: ##STR1## wherein m and n are zero or one, W and YNH and ##STR2## form the urea, thiourea, amide or amine moieties; and R.sub.1 and R .sub.2 are hydrogen or a hydrocarbon radical.

Abstract: A method of treating fungal infections in mammals employing 1,3,5-trisubstituted-4- (4-hydroxy-2-oxo-pyran-6-yl)pyrazoles is disclosed.