Patents by Inventor Michel Bublot

Michel Bublot has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified Marek's Disease Virus, and Vaccines Made Therefrom
    Publication number: 20230310589
    Abstract: The present invention provides an effective vaccine for Marek's disease, which may be prepared using a recombinant Marek's Disease Virus (MDV), strain CVI988, having been transformed with a foreign DNA construct that includes a long terminal repeat sequence of a reticuloendotheliosis virus. This safe viral agent elicits a highly protective immune response in a chicken against virulent MDV challenge without causing a significant degree of pathogenicity. Suitable formulations of the vaccine for use in chickens include an effective immunization dosage of this novel viral agent, along with a pharmaceutically acceptable carrier or diluent.
    Type: Application
    Filed: November 23, 2022
    Publication date: October 5, 2023
    Applicant: Boehringer Ingelheim Animal Health USA Inc.
    Inventors: Joyce PRITCHARD, Teshome MEBATSION, Michel BUBLOT
  • RECOMBINANT HVT VECTORS EXPRESSING MULTIPLE ANTIGENS OF AVIAN PATHOGENS AND USES THEREOF
    Publication number: 20230175017
    Abstract: The invention relates to a bonding and forming device for an inner box of a paper box and surface paper.
    Type: Application
    Filed: July 15, 2022
    Publication date: June 8, 2023
    Applicant: BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.
    Inventors: Michel Bublot, Teshome Mebatsion, Joyce Pritchard, Perry Linz, Aemro Kassa
  • Modified Marek's disease virus, and vaccines made therefrom
    Patent number: 11510978
    Abstract: The present invention provides an effective vaccine for Marek's disease, which may be prepared using a recombinant Marek's Disease Virus (MDV), strain CVI988, having been transformed with a foreign DNA construct that includes a long terminal repeat sequence of a reticuloendotheliosis virus. This safe viral agent elicits a highly protective immune response in a chicken against virulent MDV challenge without causing a significant degree of pathogenicity. Suitable formulations of the vaccine for use in chickens include an effective immunization dosage of this novel viral agent, along with a pharmaceutically acceptable carrier or diluent.
    Type: Grant
    Filed: January 30, 2019
    Date of Patent: November 29, 2022
    Assignee: Boehringer Ingelheim Animal Health USA Inc.
    Inventors: Joyce Pritchard, Teshome Mebatsion, Michel Bublot
  • Recombinant HVT vectors expressing multiple antigens of avian pathogens and uses thereof
    Patent number: 11421249
    Abstract: The present invention provides recombinant herpesvirus of turkeys (HVT) vectors that contain and express antigens of avian pathogens, compositions comprising the recombinant HVT vectors and polyvalent vaccines comprising the recombinant HVT vectors. The present invention further provides methods of vaccination against a variety of avian pathogens and method of producing the recombinant HVT vectors.
    Type: Grant
    Filed: September 28, 2020
    Date of Patent: August 23, 2022
    Assignee: BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.
    Inventors: Michel Bublot, Teshome Mebatsion, Joyce Pritchard, Perry Linz, Aemro Kassa
  • RECOMBINANT HVT VECTORS EXPRESSING MULTIPLE ANTIGENS OF AVIAN PATHOGENS AND USES THEREOF
    Publication number: 20210010033
    Abstract: The present invention provides recombinant herpesvirus of turkeys (HVT) vectors that contain and express antigens of avian pathogens, compositions comprising the recombinant HVT vectors and polyvalent vaccines comprising the recombinant HVT vectors. The present invention further provides methods of vaccination against a variety of avian pathogens and method of producing the recombinant HVT vectors.
    Type: Application
    Filed: September 28, 2020
    Publication date: January 14, 2021
    Applicant: BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.
    Inventors: Michel Bublot, Teshome Mebatsion, Joyce Pritchard, Perry Linz, Aemro Kassa
  • Recombinant HVT vectors expressing multiple antigens of avian pathogens and uses thereof
    Patent number: 10822620
    Abstract: The present invention provides recombinant herpesvirus of turkeys (HVT) vectors that contain and express antigens of avian pathogens, compositions comprising the recombinant HVT vectors and polyvalent vaccines comprising the recombinant HVT vectors. The present invention further provides methods of vaccination against a variety of avian pathogens and method of producing the recombinant HVT vectors.
    Type: Grant
    Filed: April 24, 2019
    Date of Patent: November 3, 2020
    Assignee: BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.
    Inventors: Michel Bublot, Teshome Mebatsion, Joyce Pritchard, Perry Linz, Aemro Kassa
  • RECOMBINANT HVT VECTORS EXPRESSING MULTIPLE ANTIGENS OF AVIAN PATHOGENS AND USES THEREOF
    Publication number: 20190249196
    Abstract: The present invention provides recombinant herpesvirus of turkeys (HVT) vectors that contain and express antigens of avian pathogens, compositions comprising the recombinant HVT vectors and polyvalent vaccines comprising the recombinant HVT vectors. The present invention further provides methods of vaccination against a variety of avian pathogens and method of producing the recombinant HVT vectors.
    Type: Application
    Filed: April 24, 2019
    Publication date: August 15, 2019
    Applicant: BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.
    Inventors: Michel Bublot, Teshome Mebatsion, Joyce Pritchard, Perry Linz, Aemro Kassa
  • Modified Marek's Disease Virus, and Vaccines Made Therefrom
    Publication number: 20190216920
    Abstract: The present invention provides an effective vaccine for Marek's disease, which may be prepared using a recombinant Marek's Disease Virus (MDV), strain CVI988, having been transformed with a foreign DNA construct that includes a long terminal repeat sequence of a reticuloendotheliosis virus. This safe viral agent elicits a highly protective immune response in a chicken against virulent MDV challenge without causing a significant degree of pathogenicity. Suitable formulations of the vaccine for use in chickens include an effective immunization dosage of this novel viral agent, along with a pharmaceutically acceptable carrier or diluent.
    Type: Application
    Filed: January 30, 2019
    Publication date: July 18, 2019
    Applicant: Boehringer Ingelheim Animal Health USA Inc.
    Inventors: Joyce Pritchard, Teshome Mebatsion, Michel Bublot
  • Newcastle disease virus vectored avian vaccines
    Patent number: 10350286
    Abstract: The present invention encompasses engineered Newcastle Disease Virus (NDV) vaccines or compositions. The vaccine or composition may be a recombinant vaccine. The invention also encompasses recombinant vectors encoding and expressing avian pathogen antigens, more specifically avian influenza proteins, epitopes or immunogens. Such vaccines or compositions can be used to protect animals, in particular avian, against disease.
    Type: Grant
    Filed: February 16, 2017
    Date of Patent: July 16, 2019
    Assignee: BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.
    Inventors: Michel Bublot, Frederic Reynard, François-Xavier Le Gros
  • Recombinant HVT vectors expressing multiple antigens of avian pathogens and uses thereof
    Patent number: 10323257
    Abstract: The present invention provides recombinant herpesvirus of turkeys (HVT) vectors that contain and express antigens of avian pathogens, compositions comprising the recombinant HVT vectors and polyvalent vaccines comprising the recombinant HVT vectors. The present invention further provides methods of vaccination against a variety of avian pathogens and method of producing the recombinant HVT vectors.
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: June 18, 2019
    Assignee: BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.
    Inventors: Michel Bublot, Teshome Mebatsion, Joyce Pritchard, Perry Linz, Aemro Kassa
  • RECOMBINANT HVT VECTORS EXPRESSING MULTIPLE ANTIGENS OF AVIAN PATHOGENS AND USES THEREOF
    Publication number: 20180163230
    Abstract: The present invention provides recombinant herpesvirus of turkeys (HVT) vectors that contain and express antigens of avian pathogens, compositions comprising the recombinant HVT vectors and polyvalent vaccines comprising the recombinant HVT vectors. The present invention further provides methods of vaccination against a variety of avian pathogens and method of producing the recombinant HVT vectors.
    Type: Application
    Filed: December 13, 2017
    Publication date: June 14, 2018
    Applicant: MERIAL, INC.
    Inventors: Michel Bublot, Teshome Mebatsion, Joyce Pritchard, Perry Linz, Aemro Kassa
  • Recombinant gallid herpesvirus 3 (MDV serotype 2) vectors expressing antigens of avian pathogens and uses thereof
    Patent number: 9770502
    Abstract: The present invention provides recombinant Gallid herpesvirus 3 (MDV-2) vectors that contain and express antigens of avian pathogens, recombinant Gallid herpesvirus 3 (MDV-2) vectors that contain a mutated gC gene, compositions comprising the recombinant Gallid herpesvirus 3 (MDV-2) vectors, polyvalent vaccines comprising the recombinant Gallid herpesvirus 3 (MDV-2) vectors and one or more wild type viruses or recombinant vectors. The present invention further provides methods of vaccination against a variety of avian pathogens and method of producing the recombinant Gallid herpesvirus 3 (MDV-2) vectors.
    Type: Grant
    Filed: April 9, 2015
    Date of Patent: September 26, 2017
    Assignee: MERIAL, INC.
    Inventors: Michel Bublot, Teshome Mebatsion, Joyce Pritchard, Perry Linz
  • NEWCASTLE DISEASE VIRUS VECTORED AVIAN VACCINES
    Publication number: 20170224807
    Abstract: The present invention encompasses engineered Newcastle Disease Virus (NDV) vaccines or compositions. The vaccine or composition may be a recombinant vaccine. The invention also encompasses recombinant vectors encoding and expressing avian pathogen antigens, more specifically avian influenza proteins, epitopes or immunogens. Such vaccines or compositions can be used to protect animals, in particular avian, against disease.
    Type: Application
    Filed: February 16, 2017
    Publication date: August 10, 2017
    Applicant: Merial Inc.
    Inventors: Michel Bublot, Frederic REYNARD, François-Xavier LE GROS
  • Newcastle disease virus vectored avian vaccines
    Patent number: 9616118
    Abstract: The present invention encompasses engineered Newcastle Disease Virus (NDV) vaccines or compositions. The vaccine or composition may be a recombinant vaccine. The invention also encompasses recombinant vectors encoding and expressing avian pathogen antigens, more specifically avian influenza proteins, epitopes or immunogens. Such vaccines or compositions can be used to protect animals, in particular avian, against disease.
    Type: Grant
    Filed: May 2, 2014
    Date of Patent: April 11, 2017
    Assignee: MERIAL, INC.
    Inventors: Michel Bublot, Frederic Reynard, François-Xavier Le Gros
  • Recombinant HVT vectors expressing antigens of avian pathogens and uses thereof
    Patent number: 9555096
    Abstract: The present invention provides recombinant herpesvirus of turkeys (HVT) vectors that contain and express antigens of avian pathogens, compositions comprising the recombinant HVT vectors, polyvalent vaccines comprising the recombinant HVT vectors and one or more wild type viruses or recombinant vectors. The present invention further provides methods of vaccination against a variety of avian pathogens and method of producing the recombinant HVT vectors.
    Type: Grant
    Filed: June 23, 2015
    Date of Patent: January 31, 2017
    Assignee: MERIAL, INC.
    Inventors: Michel Bublot, Teshome Mebatsion, Joyce Pritchard, Perry Linz
  • Newcastle disease virus vectored herpesvirus vaccines
    Patent number: 9446118
    Abstract: The present invention encompasses recombinant Newcastle Disease Virus-Herpesvirus vaccines or compositions. The invention encompasses recombinant NDV vectors encoding and expressing herpesvirus pathogen, antigens, proteins, epitopes or immunogens. Such vaccines or compositions can be used to protect animals against disease.
    Type: Grant
    Filed: February 6, 2015
    Date of Patent: September 20, 2016
    Assignee: Merial, Inc.
    Inventors: Michel Bublot, Frederic Reynard, Herve Poulet, Frederic Raymond David
  • RECOMBINANT GALLID HERPESVIRUS 3 (MDV SEROTYPE 2) VECTORS EXPRESSING ANTIGENS OF AVIAN PATHOGENS AND USES THEREOF
    Publication number: 20160015801
    Abstract: The present invention provides recombinant Gallid herpesvirus 3 (MDV-2) vectors that contain and express antigens of avian pathogens, recombinant Gallid herpesvirus 3 (MDV-2) vectors that contain a mutated gC gene, compositions comprising the recombinant Gallid herpesvirus 3 (MDV-2) vectors, polyvalent vaccines comprising the recombinant Gallid herpesvirus 3 (MDV-2) vectors and one or more wild type viruses or recombinant vectors. The present invention further provides methods of vaccination against a variety of avian pathogens and method of producing the recombinant Gallid herpesvirus 3 (MDV-2) vectors.
    Type: Application
    Filed: April 9, 2015
    Publication date: January 21, 2016
    Applicant: MERIAL, INC.
    Inventors: Michel Bublot, Teshome Mebatsion, Joyce Pritchard, Perry Linz
  • RECOMBINANT HVT VECTORS EXPRESSING ANTIGENS OF AVIAN PATHOGENS AND USES THEREOF
    Publication number: 20150283225
    Abstract: The present invention provides recombinant herpesvirus of turkeys (HVT) vectors that contain and express antigens of avian pathogens, compositions comprising the recombinant HVT vectors, polyvalent vaccines comprising the recombinant HVT vectors and one or more wild type viruses or recombinant vectors. The present invention further provides methods of vaccination against a variety of avian pathogens and method of producing the recombinant HVT vectors.
    Type: Application
    Filed: June 23, 2015
    Publication date: October 8, 2015
    Applicant: MERIAL INC.
    Inventors: Michel Bublot, Teshome Mebatsion, Joyce Pritchard, Perry Linz
  • Recombinant HVT vectors expressing antigens of avian pathogens and uses thereof
    Patent number: 9114108
    Abstract: The present invention provides recombinant herpesvirus of turkeys (HVT) vectors that contain and express antigens of avian pathogens, compositions comprising the recombinant HVT vectors, polyvalent vaccines comprising the recombinant HVT vectors and one or more wild type viruses or recombinant vectors. The present invention further provides methods of vaccination against a variety of avian pathogens and method of producing the recombinant HVT vectors.
    Type: Grant
    Filed: November 29, 2012
    Date of Patent: August 25, 2015
    Assignee: MERIAL, INC.
    Inventors: Michel Bublot, Teshome Mebatsion, Joyce Pritchard, Perry Linz
  • Recombinant Gallid herpesvirus 3 (MDV serotype 2) vectors expressing antigens of avian pathogens and uses thereof
    Patent number: 9101598
    Abstract: The present invention provides recombinant Gallid herpesvirus 3 (MDV-2) vectors that contain and express antigens of avian pathogens, recombinant Gallid herpesvirus 3 (MDV-2) vectors that contain a mutated gC gene, compositions comprising the recombinant Gallid herpesvirus 3 (MDV-2) vectors, polyvalent vaccines comprising the recombinant Gallid herpesvirus 3 (MDV-2) vectors and one or more wild type viruses or recombinant vectors. The present invention further provides methods of vaccination against a variety of avian pathogens and method of producing the recombinant Gallid herpesvirus 3 (MDV-2) vectors.
    Type: Grant
    Filed: November 29, 2012
    Date of Patent: August 11, 2015
    Assignee: MERIAL, INC.
    Inventors: Michel Bublot, Teshome Mebatsion, Joyce Pritchard, Perry Linz