Patents by Inventor Michel Bublot

Michel Bublot has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150157704
    Abstract: The present invention encompasses recombinant Newcastle Disease Virus-Herpesvirus vaccines or compositions. The invention encompasses recombinant NDV vectors encoding and expressing herpesvirus pathogen, antigens, proteins, epitopes or immunogens. Such vaccines or compositions can be used to protect animals against disease.
    Type: Application
    Filed: February 6, 2015
    Publication date: June 11, 2015
    Applicant: MERIAL LIMITED
    Inventors: Michel Bublot, Frederic Reynard, Herve Poulet, Frederic Raymond David
  • Patent number: 8986706
    Abstract: The present invention encompasses recombinant Newcastle Disease Virus-Herpesvirus vaccines or compositions. The invention encompasses recombinant NDV vectors encoding and expressing herpesvirus pathogen, antigens, proteins, epitopes or immunogens. Such vaccines or compositions can be used to protect animals against disease.
    Type: Grant
    Filed: August 29, 2011
    Date of Patent: March 24, 2015
    Assignee: Merial, Inc.
    Inventors: Michel Bublot, Frederic Reynard, Herve Poulet, Frederic Raymond David
  • Publication number: 20140341950
    Abstract: The present invention encompasses engineered APMV compositions or vaccines. The vaccine or composition may be a recombinant APMV composition or vaccine. The present invention encompasses methods for modifying the genome of APMV to produce recombinant APMV; modified APMV prepared by such methods; DNA and protein sequences; and methods for infecting cells and host animals with such recombinant APMV.
    Type: Application
    Filed: May 15, 2013
    Publication date: November 20, 2014
    Applicants: UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC., MERIAL LIMITED
    Inventors: Michel Bublot, Teshome Mebatsion, Joyce Pritchard, Egbert Mundt
  • Patent number: 8871220
    Abstract: The present invention encompasses engineered Newcastle Disease Virus (NDV) vaccines or compositions. The vaccine or composition may be a recombinant vaccine. The invention also encompasses recombinant vectors encoding and expressing avian pathogen antigens, more specifically avian influenza proteins, epitopes or immunogens. Such vaccines or compositions can be used to protect animals, in particular avian, against disease.
    Type: Grant
    Filed: April 2, 2010
    Date of Patent: October 28, 2014
    Assignee: Merial Limited
    Inventors: Michel Bublot, Frederic Reynard, François-Xavier Le Gros
  • Publication number: 20140234358
    Abstract: The present invention encompasses engineered Newcastle Disease Virus (NDV) vaccines or compositions. The vaccine or composition may be a recombinant vaccine. The invention also encompasses recombinant vectors encoding and expressing avian pathogen antigens, more specifically avian influenza proteins, epitopes or immunogens. Such vaccines or compositions can be used to protect animals, in particular avian, against disease.
    Type: Application
    Filed: May 2, 2014
    Publication date: August 21, 2014
    Applicant: MERIAL LIMITED
    Inventors: Michel Bublot, Frederic REYNARD, François-Xavier LE GROS
  • Publication number: 20140205619
    Abstract: The present invention encompasses influenza vaccines, in particular avian influenza vaccines. The vaccine may be a subunit vaccine based on the hemagglutinin of influenza. The hemagglutinin may be expressed in plants including duckweed. The invention also encompasses recombinant vectors encoding and expressing influenza antigens, epitopes or immunogens which can be used to protect animals against influenza. It encompasses also a vaccination regimen compatible with the DIVA strategy, including a prime-boost scheme using vector and subunit vaccines.
    Type: Application
    Filed: January 13, 2014
    Publication date: July 24, 2014
    Applicants: BIOLEX THERAPEUTICS, INC., MERIAL LIMITED
    Inventors: Xuan Guo, Michel Bublot, Joyce Anita Pritchard, Lynn Dickey
  • Publication number: 20140205993
    Abstract: The present invention encompasses influenza vaccines, in particular avian influenza vaccines. The vaccine may be a subunit vaccine based on the hemagglutinin of influenza. The hemagglutinin may be expressed in plants including duckweed. The invention also encompasses recombinant vectors encoding and expressing influenza antigens, epitopes or immunogens which can be used to protect animals against influenza. It encompasses also a vaccination regimen compatible with the DIVA strategy, including a prime-boost scheme using vector and subunit vaccines.
    Type: Application
    Filed: January 18, 2013
    Publication date: July 24, 2014
    Applicants: Biolex Therapeutics, Inc., Merial Limited
    Inventors: Xuan Guo, Michel Bublot, Joyce Anita Pritchard, Lynn Dickey
  • Publication number: 20140147465
    Abstract: The present invention provides recombinant Gallid herpesvirus 3 (MDV-2) vectors that contain and express antigens of avian pathogens, recombinant Gallid herpesvirus 3 (MDV-2) vectors that contain a mutated gC gene, compositions comprising the recombinant Gallid herpesvirus 3 (MDV-2) vectors, polyvalent vaccines comprising the recombinant Gallid herpesvirus 3 (MDV-2) vectors and one or more wild type viruses or recombinant vectors. The present invention further provides methods of vaccination against a variety of avian pathogens and method of producing the recombinant Gallid herpesvirus 3 (MDV-2) vectors.
    Type: Application
    Filed: November 29, 2012
    Publication date: May 29, 2014
    Applicant: Merial Limited
    Inventors: Michel Bublot, Teshome Mebatsion, Joyce Pritchard, Perry Linz
  • Publication number: 20140147457
    Abstract: The present invention provides recombinant herpesvirus of turkeys (HVT) vectors that contain and express antigens of avian pathogens, compositions comprising the recombinant HVT vectors, polyvalent vaccines comprising the recombinant HVT vectors and one or more wild type viruses or recombinant vectors. The present invention further provides methods of vaccination against a variety of avian pathogens and method of producing the recombinant HVT vectors.
    Type: Application
    Filed: November 29, 2012
    Publication date: May 29, 2014
    Applicant: Merial Limited
    Inventors: Michel Bublot, Teshome Mebatsion, Joyce Pritchard, Perry Linz
  • Publication number: 20130251737
    Abstract: The present invention provides an effective vaccine for Marek's disease, which may be prepared using a recombinant Marek's Disease Virus (MDV), strain CVI988, having been transformed with a foreign DNA construct that includes a long terminal repeat sequence of a reticuloendotheliosis virus. This safe viral agent elicits a highly protective immune response in a chicken against virulent MDV challenge without causing a significant degree of pathogenicity. Suitable formulations of the vaccine for use in chickens include an effective immunization dosage of this novel viral agent, along with a pharmaceutically acceptable carrier or diluent.
    Type: Application
    Filed: March 15, 2013
    Publication date: September 26, 2013
    Applicant: MERIAL LIMITED
    Inventors: Joyce Pritchard, Teshome Mebatsion, Michel Bublot
  • Patent number: 8486418
    Abstract: The present invention encompasses engineered APMV compositions or vaccines. The vaccine or composition may be a recombinant APMV composition or vaccine. The present invention encompasses methods for modifying the genome of APMV to produce recombinant APMV; modified APMV prepared by such methods; DNA and protein sequences; and methods for infecting cells and host animals with such recombinant APMV.
    Type: Grant
    Filed: August 20, 2010
    Date of Patent: July 16, 2013
    Assignees: Merial Limited, University of Georgia Research Foundation, Inc.
    Inventors: Michel Bublot, Teshome Mebatsion, Joyce Pritchard, Egburt Mundt
  • Patent number: 8394384
    Abstract: The present invention encompasses influenza vaccines, in particular avian influenza vaccines. The vaccine may be a subunit vaccine based on the hemagglutinin of influenza. The hemagglutinin may be expressed in plants including duckweed. The invention also encompasses recombinant vectors encoding and expressing influenza antigens, epitopes or immunogens which can be used to protect animals against influenza. It encompasses also a vaccination regimen compatible with the DIVA strategy, including a prime-boost scheme using vector and subunit vaccines.
    Type: Grant
    Filed: November 30, 2009
    Date of Patent: March 12, 2013
    Assignees: Merial Limited, Biolex Therapeutics, Inc.
    Inventors: Xuan Guo, Michel Bublot, Joyce A. Pritchard, Lynn F. Dickey
  • Publication number: 20120052089
    Abstract: The present invention encompasses recombinant Newcastle Disease Virus-Herpesvirus vaccines or compositions. The invention encompasses recombinant NDV vectors encoding and expressing herpesvirus pathogen, antigens, proteins, epitopes or immunogens. Such vaccines or compositions can be used to protect animals against disease.
    Type: Application
    Filed: August 29, 2011
    Publication date: March 1, 2012
    Inventor: Michel Bublot
  • Publication number: 20110236416
    Abstract: The present invention encompasses FMDV vaccines or compositions. The vaccine or composition may be a vaccine or composition containing FMDV antigens. The invention also encompasses recombinant vectors encoding and expressing FMDV antigens, epitopes or immunogens which can be used to protect animals, in particular ovines, bovines, caprines, or porcines, against FMDV.
    Type: Application
    Filed: March 11, 2011
    Publication date: September 29, 2011
    Inventors: Jean-Christophe Audonnet, Xuan Guo, Bradley J. Feilmeir, Karolyn Marie Troupe, Michel Bublot, Kevin Cox
  • Publication number: 20110081374
    Abstract: The present invention encompasses engineered APMV compositions or vaccines. The vaccine or composition may be a recombinant APMV composition or vaccine. The present invention encompasses methods for modifying the genome of APMV to produce recombinant APMV; modified APMV prepared by such methods; DNA and protein sequences; and methods for infecting cells and host animals with such recombinant APMV.
    Type: Application
    Filed: August 20, 2010
    Publication date: April 7, 2011
    Inventors: Michel Bublot, Teshome Mebatsion, Joyce Pritchard, Egburt Mundt
  • Patent number: 7910112
    Abstract: The present invention encompasses influenza vaccines, in particular avian influenza vaccines. The vaccine may be a recombinant poxvirus vaccine or an inactivated vaccine. The invention also encompasses recombinant poxvirus vectors encoding and expressing avian influenza antigens, epitopes or immunogens which can be used to protect animals, in particular felids, against avian influenza.
    Type: Grant
    Filed: November 6, 2006
    Date of Patent: March 22, 2011
    Assignee: Merial Limited
    Inventors: Hervé Poulet, Jean Christophe Audonnet, Michel Bublot, Jiansheng Yao
  • Publication number: 20100255029
    Abstract: The present invention encompasses engineered Newcastle Disease Virus (NDV) vaccines or compositions. The vaccine or composition may be a recombinant vaccine. The invention also encompasses recombinant vectors encoding and expressing avian pathogen antigens, more specifically avian influenza proteins, epitopes or immunogens. Such vaccines or compositions can be used to protect animals, in particular avian, against disease.
    Type: Application
    Filed: April 2, 2010
    Publication date: October 7, 2010
    Inventors: MICHEL BUBLOT, FRANÇOIS-XAVIER LE GROS, FREDERIC REYNARD
  • Publication number: 20100189731
    Abstract: The present invention encompasses influenza vaccines, in particular avian influenza vaccines. The vaccine may be a subunit vaccine based on the hemagglutinin of influenza. The hemagglutinin may be expressed in plants including duckweed. The invention also encompasses recombinant vectors encoding and expressing influenza antigens, epitopes or immunogens which can be used to protect animals against influenza. It encompasses also a vaccination regimen compatible with the DIVA strategy, including a prime-boost scheme using vector and subunit vaccines.
    Type: Application
    Filed: November 30, 2009
    Publication date: July 29, 2010
    Inventors: Xuan GUO, Michel Bublot, Joyce A. Pritchard, Lynn F. Dickey
  • Patent number: 7250161
    Abstract: Disclosed and/or claimed is subject matter including: equine GM-CSF, its amino acid sequence, nucleic acid molecules encoding equine GM-CSF, use of equine GM-CSF as an adjuvant or non-specific immunity stimulant, compositions containing equine GM-CSF and vectors expressing GM-CSF.
    Type: Grant
    Filed: July 7, 2003
    Date of Patent: July 31, 2007
    Assignee: Uerial LLC
    Inventors: Michel Bublot, Jennifer Maria Perez, Christine Michele Pierrette Andreoni
  • Patent number: 6943152
    Abstract: The invention relates to immunogenic preparations or vaccines comprising, on the one hand, a plasmid encoding and expressing a gene from PCV, in particular selected from the group consisting of ORF1 of PCV-2, ORF2 of PCV-2, ORF1 of PCV-1 and ORF2 of PCV-1, and, on the other hand, an element capable of increasing the immune response directed against the product of expression of the gene, which can be a carbomer, a porcine cytokine, e.g. GM-CSF or a cationic lipid of formula in which R1 is a saturated or unsaturated linear aliphatic radical having from 12 to 18 carbon atoms, R2 is another aliphatic radical comprising from 2 to 3 carbon atoms, andt X is an hydroxyle ou amine group. The cationic lipid can be DMRIE, possibly coupled with DOPE.
    Type: Grant
    Filed: May 31, 2000
    Date of Patent: September 13, 2005
    Assignee: Merial
    Inventors: Francis Jean-Christophe Audonnet, Michel Bublot, Jennifer Maria Perez, Catherine Elisabeth Charreyre