Abstract: A fused heterocyclic compound having an enteropeptidase inhibitory action and use of the compound as a medicament for treatment or prophylaxis of obesity, diabetes mellitus, etc., are provided. Specifically, a compound represented by the following formula (I): wherein each symbol is as defined herein, or a salt thereof and use of the compound as a medicament for treatment or prophylaxis of obesity, diabetes mellitus, etc., are provided.

Abstract: Provided is an aromatic ring compound having a glucagon antagonistic action, which is useful for the prophylaxis or treatment of diabetes and the like. A compound represented by the formula (I): wherein each symbol is as defined in the DESCRIPTION, or a salt thereof has a superior glucagon antagonistic action, and is useful as a glucagon antagonist, a glucose production inhibitor or an agent for the prophylaxis or treatment of diabetes and the like.

Abstract: Provided is an aromatic ring compound having a glucagon antagonistic action, which is useful for the prophylaxis or treatment of diabetes and the like. A compound represented by the formula (I): wherein each symbol is as defined in the DESCRIPTION, or a salt thereof has a superior glucagon antagonistic action, and is useful as a glucagon antagonist, a glucose production inhibitor or an agent for the prophylaxis or treatment of diabetes and the like.

Abstract: Heterocyclic compounds, pharmaceutical agent and methods thereof, having superior pharmacological action and/or physicochemical properties, which are useful for the prophylaxis or treatment of circulatory diseases such as hypertension, cardiac diseases, arteriosclerosis, renal diseases and cerebral apoplexy and/or metabolic diseases such as hyperlipidemia, obesity and diabetes and/or central nervous disorders such as cerebral infarction, and/or mental diseases such as dementia depression and depression.

Abstract: A process for the production of a semi-solidified iron alloy slurry having a crystallized solid phase and a residual liquid phase, wherein a material having a hypoeutectic cast iron composition is used, and an additive agent having a boiling point that is lower than at least a crystallization initiation temperature of primary crystals of the material is added to a melt of the material when the melt temperature is within a specific temperature range of not lower than the crystallization initiation temperature of the primary crystals and not greater than a temperature that is 50° C. higher than the crystallization initiation temperature, to thereby simultaneously conduct the stirring of the melt by the boiling of the additive agent and the cooling of the melt to a temperature falling within a semi-solidification temperature range thereof.

Abstract: A contactor electrically connects and disconnects a fuel cell from a load. When a failure-detecting mode for detecting a closing failure of a contactor is initiated, an opening command is transmitted to the contactor, and a DC/DC converter connected to a motor changes the load voltage. Then, the load voltage and a fuel cell voltage are compared with each other. If the contactor is in a normal open state, as a result of the opening command, the fuel cell voltage is constant, whereas the load voltage of the DC/DC converter decreases, thereby producing a voltage difference. A closing failure of the contactor is determined when it is detected that the fuel cell voltage is substantially equal to the load voltage.

Abstract: A refrigerant cycle device for a vehicle includes a compressor which compresses and discharges refrigerant, a discharge capacity control portion which controls a discharge capacity of the compressor. The refrigerant cycle device further includes a noise determination portion which determines whether an audible noise other than a refrigerant passing noise is in a low noise state, and/or a load determination portion which determines whether an air-conditioning thermal load is in a high load state. The discharge capacity control portion performs a gradual activation control in which the discharge capacity of the compressor is set to be lower than that determined in a normal control, when the noise determination portion determines that the audible noise is in the low noise state, and/or when the load determination portion determines that the air-conditioning thermal load is in the high load state, at an activation time of the compressor.

Abstract: A system for locating a vehicle may include a hand-held device and a communication device on-board the vehicle. The hand-held device may include a screen, and may be adapted to import a map and display a present location of the hand-held device on the map. The communication device on-board the vehicle may be adapted to communicate a present location of the vehicle to the hand-held device. The hand-held device may be capable of displaying the location of the vehicle and the location of the hand-held device on the map at the same time.

Abstract: A system for locating a vehicle may include a hand-held device and a communication device on-board the vehicle. The hand-held device may include a screen, and may be adapted to import a map and display a present location of the hand-held device on the map. The communication device on-board the vehicle may be adapted to communicate a present location of the vehicle to the hand-held device. The hand-held device may be capable of displaying the location of the vehicle and the location of the hand-held device on the map at the same time.

Abstract: A system for locating a vehicle may include a hand-held device and a communication device on-board the vehicle. The hand-held device may include a screen, and may be adapted to import a map and display a present location of the hand-held device on the map. The communication device on-board the vehicle may be adapted to communicate a present location of the vehicle to the hand-held device. The hand-held device may be capable of displaying the location of the vehicle and the location of the hand-held device on the map at the same time.

Abstract: A process for producing a semi-solidified slurry of an iron alloy including the steps of pouring a melt of an iron alloy into a semi-solidified slurry producing vessel 30 and cooling the melt therein to obtain a semi-solidified slurry having a crystallized solid phase and a residual liquid phase, wherein a hypereutectoid or hypoeutectic cast iron composition containing 0.8-4.3 wt. % C is used as a material, a melt of the composition is poured into the semi-solidified slurry producing vessel in a predetermined amount at a time, a temperature of the melt when poured into the semi-solidified slurry producing vessel is controlled to be not lower than a crystallization initiation temperature of the composition and not greater than a temperature that is 50° C. higher than the crystallization initiation temperature, and a cooling rate of the melt poured into the semi-solidified slurry producing vessel is controlled not to exceed 20° C. per minute.

Abstract: A process for the production of a semi-solidified iron alloy slurry having a crystallized solid phase and a residual liquid phase, wherein a material having a hypoeutectic cast iron composition is used, and an additive agent having a boiling point that is lower than at least a crystallization initiation temperature of primary crystals of the material is added to a melt of the material when the melt temperature is within a specific temperature range of not lower than the crystallization initiation temperature of the primary crystals and not greater than a temperature that is 50° C. higher than the crystallization initiation temperature, to thereby simultaneously conduct the stirring of the melt by the boiling of the additive agent and the cooling of the melt to a temperature falling within a semi-solidification temperature range thereof.

Abstract: A compound represented by the formula (I): wherein R1 is an oxo group, ?N—R or the like; a group represented by the formula: is a group represented by the formula: R2 is a group represented by the formula: R3 and R4 are each H, or C1-C6 alkyl, C3-C6 cycloalkyl, C1-C6 alkoxy, C1-C6 alkylamino, di(C1-C6)alkylamino or C1-C6 alkylthio, each of which is optionally substituted; and R5 is H, or C1-C6 alkyl, C2-C6 alkenyl, cyclic group, each of which is optionally substituted, —CO—R8 or —O—R8?, or a salt thereof. For example, the compound may be substituted pyrimidines and pharmaceutical compositions of the formula (I) where X=—CR3; X1=—CR2 or —NR2; and X2=—CR5 or —NR5. The compound of the present invention is useful as a drug for the prophylaxis or treatment of cardiovascular diseases, metabolic diseases and/or central nervous system diseases.

Abstract: A process for producing a semi-solidified slurry of an iron alloy including the steps of pouring a melt of an iron alloy into a semi-solidified slurry producing vessel 30 and cooling the melt therein to obtain a semi-solidified slurry having a crystallized solid phase and a residual liquid phase, wherein a hypoeutectic cast iron composition is used as a material, a melt of the composition is poured into the semi-solidified slurry producing vessel 30 in a predetermined amount at a time, a temperature of the melt when poured into the semi-solidified slurry producing vessel 30 is controlled to be not lower than a crystallization initiation temperature of the composition and not greater than a temperature that is 50° C. higher than the crystallization initiation temperature, and a cooling rate of the melt poured into the semi-solidified slurry producing vessel 30 is controlled not to exceed 20° C. per minute.

Abstract: The invention can provide a miniaturized noise filter. The noise filter for reducing noise comprises a coil with a conductive wire (2) wound around a core (1); a case (6) formed of an insulating material receiving the coil; a bracket (8) of a magnetic material forming a flux path of magnetic flux generated from the coil, which places the case thereon, which has a pair of end plates (12a, 12b) disposed opposite to both ends of the core of the coil respectively through a gap of a predetermined distance, and which has a bottom plate (8a) disposed between the pair of the end plates; and an input/output terminal (3a, 3b) for the coil.

Abstract: A compound represented by the formula (I): wherein R1 is an oxo group, ?N—R or the like; a group represented by the formula: is a group represented by the formula: R2 is a group represented by the formula: R3 and R4 are each H, or C1-C6 alkyl, C3-C6 cycloalkyl, C1-C6 alkoxy, C1-C6 alkylamino, di(C1-C6)alkylamino or C1-C6 alkylthio, each of which is optionally substituted; and R5 is H, or C1-C6 alkyl, C2-C6 alkenyl, cyclic group, each of which is optionally substituted, —CO—R8 or —O—R8?, or a salt thereof. The compound of the present invention is useful as a drug for the prophylaxis or treatment of cardiovascular diseases, metabolic diseases and/or central nervous system diseases.

Abstract: A contactor electrically connects and disconnects a fuel cell from a load. When a failure-detecting mode for detecting a closing failure of a contactor is initiated, an opening command is transmitted to the contactor, and a DC/DC converter connected to a motor changes the load voltage. Then, the load voltage and a fuel cell voltage are compared with each other. If the contactor is in a normal open state, as a result of the opening command, the fuel cell voltage is constant, whereas the load voltage of the DC/DC converter decreases, thereby producing a voltage difference. A closing failure of the contactor is determined when it is detected that the fuel cell voltage is substantially equal to the load voltage.

Abstract: A contactor electrically connects and disconnects a fuel cell from a load. When a failure-detecting mode for detecting a closing failure of a contactor is initiated, an opening command is transmitted to the contactor, and a DC/DC converter connected to a motor changes the load voltage. Then, the load voltage and a fuel cell voltage are compared with each other. If the contactor is in a normal open state, as a result of the opening command, the fuel cell voltage is constant, whereas the load voltage of the DC/DC converter decreases, thereby producing a voltage difference. A closing failure of the contactor is determined when it is detected that the fuel cell voltage is substantially equal to the load voltage.

Abstract: A compound represented by the formula (I): wherein R1 is an oxo group, ?N—R or the like; a group represented by the formula: is a group represented by the formula: R2 is a group represented by the formula: R3 and R4 are each H, or C1-C6 alkyl, C3-C6 cycloalkyl, C1-C6 alkoxy, C1-C6 alkylamino, di(C1-C6)alkylamino or C1-C6 alkylthio, each of which is optionally substituted; and R5 is H, or C1-C6 alkyl, C2-C6 alkenyl, cyclic group, each of which is optionally substituted, —CO—R8 or —O—R8?, or a salt thereof. The compound of the present invention is useful as a drug for the prophylaxis or treatment of cardiovascular diseases, metabolic diseases and/or central nervous system diseases.

Abstract: The present invention aims to provide a compound having superior pharmacological action, physicochemical properties and the like, which is useful for the prophylaxis or treatment s of circulatory diseases such as hypertension, cardiac diseases, arteriosclerosis, renal diseases, cerebral apoplexy and the like and/or metabolic diseases such as hyperlipidemia, obesity, diabetes and the like, central nervous disorders such as cerebral infarction and the like, mental diseases such as dementia, depression and the like, and the like. A compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof.