Abstract: Articles comprising first and second coextruded polymeric nettings are described. The articles comprise a plurality of pairs of first segments comprising a first material. Adjacent first segments are joined together via a second segments comprising second material, wherein the second segments extend past the first major surface of each first adjacent segments. The articles further include an adhesive on at least one of the first or second major surfaces of the first segment. The first segments, second segments, and third material each extend continuously for at least 5 mm in the machine direction, and the first and second materials of adjacent pairs are periodically bonded together in the machine direction. A portion of some of the first segments of the first coextruded polymeric netting are engaged between some of the adjacent first segments of the second coextruded polymeric netting.

Abstract: Antimicrobial compositions and articles are disclosed, as well as method for preparing antimicrobial compositions. Also disclosed are method for using antimicrobial compositions and articles for preventing the formation or growth of biofilms, disrupting biofilms, reducing microorganism counts, and treating infections.

Abstract: A wound dressing material comprises: a first water-sensitive film comprising a first copolymer comprising first divalent hydroxyethylene monomer units and first divalent dihydroxybutylene monomer units; and a first antimicrobial layer disposed on the first water-sensitive film. Methods of making and using the wound dressing material are also disclosed.

Abstract: A wound dressing material comprises a porous flexible foam core, a wound-contact scrim, and an antimicrobial layer. The wound-contact scrim comprises water-sensitive fibers comprising a copolymer comprising divalent hydroxyethylene monomer units and divalent dihydroxybutylene monomer units. The antimicrobial layer is sandwiched between the porous flexible foam core and the wound-contact scrim. The wounds dressing material may be contacted with an exposed surface of a wound. A method of making the wound dressing material is also disclosed.

Abstract: A wound dressing material comprises first and second wound-contact scrims, and an antimicrobial layer disposed therebetween. The wound-contact scrims comprise water-sensitive fibers comprising a copolymer comprising divalent hydroxyethylene monomer units and divalent dihydroxybutylene monomer units. The wound dressing material may be contacted with an exposed surface of a wound. A method of making the wound dressing material is also disclosed.

Abstract: A wound dressing material comprises a base fiber web, a wound-contact scrim, and an antimicrobial layer. The wound-contact scrim comprises water-sensitive fibers comprising a copolymer comprising divalent hydroxyethylene monomer units and divalent dihydroxybutylene monomer units. The antimicrobial layer is sandwiched between the base fiber web and the wound-contact scrim. The wounds dressing material may be contacted with an exposed surface of a wound. A method of making the wound dressing material is also disclosed.

Abstract: The present disclosure provides a solid composition that includes a polycarboxylic acid chelator component mixed with a water-soluble plasticizer component, and a water-soluble or water-dispersible polymer dissolved and/or dispersed in the plasticizer component. The water-soluble plasticizer component has a boiling point >105° C. and has a formula weight of less than 5000 atomic mass units. The composition comprises <10 wt % of a solvent that has a boiling point ?100 degrees C. When mixed with deionized water at a 1:9 mass ratio, the composition forms an aqueous mixture having a pH of about 2.5-5.5. Articles that include a substrate with a first major surface having a layer comprising the composition adhered to the first major surface are also provided. Methods of treating a biofilm or a wound site with the articles are also provided.

Abstract: A method of making a nonwoven fiber web comprises: providing a melt-blown nonwoven fiber web comprising bonded primary fibers having an average fiber diameter of 2 to 100 microns, wherein the primary fibers comprise a copolymer comprising divalent hydroxyethylene monomer units and divalent dihydroxybutylene monomer units; opening at least a portion of the melt-blown nonwoven fiber web to provide loose primary fibers; combining the loose primary fibers with secondary fibers; and forming a secondary nonwoven fiber web comprising the primary fibers and secondary fibers. A fiber web preparable according to the method and a multicomponent fiber including a first phase comprising a copolymer comprising divalent hydroxyethylene monomer units and divalent dihydroxybutylene monomer units and a second phase comprising a non-biodegradable polymer.

Abstract: Article comprising first and second coextruded polymeric nettings, the first and second coextruded polymeric nettings each having a machine direction comprising: a plurality of pairs of: first segments each having first and second opposed major surfaces and a thickness, the first segments comprising first material; second segments comprising second material, wherein adjacent first segments are joined together via a second segment, wherein the second segments extend from the second major surface past the first major surface of each first adjacent segment and has a distal end, the second segments having first and second opposed major surfaces, wherein there is a gap between adjacent second segments; and a third material comprising adhesive, different from the first and second materials on at least one the first or second major surfaces first segment, wherein the first segments, second segments, and third material each extend continuously for at least 5 mm in the machine direction, and wherein first and second m

Abstract: Coextruded polymeric netting having a machine direction comprising: a plurality of pairs of: first segments each having first and second opposed major surfaces and a thickness, the first segments comprising first material; second segments comprising second material, wherein adjacent first segments are joined together via a second segment, wherein the second segments extend from the second major surface past the first major surface of each first adjacent segment and has a distal end, the second segments having first and second opposed major surfaces, wherein there is a gap between adjacent second segments; and a third material, different from the first and second materials on at least one of the first or second major surfaces of at least every other second segment, wherein the first segments, second segments, and third material each extend continuously for at least 5 mm in the machine direction, and wherein first and second materials of adjacent pairs are periodically bonded together in the machine direction.

Abstract: Compositions including a quaternary amine antiseptic component having a concentration of at least about 0.04% by weight; a poly carboxylic acid chelator having a concentration of at least about 0.05 M and/or an alphahydroxy acid buffer having a concentration of at least about 0.05 M; a (C8-C12) 1,2 alkane diol; and optionally water are provided. The compositions have a pH greater than or equal to 3.5 and less than 5.5 at 23° C. In certain embodiments, water is present in the composition at a greater weight percent than each of the quaternary amine antiseptic component; the polycarboxylic acid chelator, if present; the alphahydroxy acid buffer, if present; and the (C8-C12) 1,2-alkane diol. In certain embodiments, water is present in the composition at a greater weight percent than any other component.

Abstract: An article. The article includes a polymer foam having a first major surface and a second major surface; and discrete domains of a therapeutic composition at least partially surrounded by the polymer foam; wherein an exterior surface of each discrete domain substantially conforms to a portion of the first major surface of the polymer foam; wherein the article comprises a first major surface and a second major surface; and wherein a portion of the first major surface of the polymer foam and the exterior surfaces of discrete domains form the first major surface of the article.

Abstract: A securement device for securing a medical article, comprising abase having a longitudinal axis, a top face and a bottom face, where the longitudinal axis defines a longitudinal direction, a cuff disposed on the top face of the base and positioned along the longitudinal axis, the cuff comprising an entry gap in at least a portion of the cuff and defining an interior aperture, and a bar disposed on the top face of the base, the bar positioned along the longitudinal axis, where the bar is moveable between an open position and a closed position and where the bar cooperates with the cuff in the closed position to secure the medical article.

Abstract: A medical article and methods of using same. The medical article can include a machine direction (MD) and a cross-machine direction (CMD); a support layer; and a viscoelastic layer. The viscoelastic layer can be coupled to the support layer, and the viscoelastic layer can be discontinuous in the MD and/or the CMD. The viscoelastic layer can recover at least 70% of its deformation after 48 hours at room temperature after being strained to 50% elongation, such that the medical article has a first tensile stiffness T1 at a first strain rate S1, and a second tensile stiffness T1 at a second strain rate S1. The ratio of S1/S2 can be at least 100, and the ratio of T1/T2 can be at least 1.5. The method can include wrapping the medical article around a body part; applying the first strain rate S1; and applying the second strain rate S2.

Abstract: The present application is directed to a method of using a hardenable dental article. The method can include providing the hardenable dental article; applying the hardenable dental article to a dental structure; customizing the shape of the hardenable dental article; and at least partially curing the hardenable dental article.

Abstract: A method of using hardenable dental articles. The method can include placing a film (30) onto a dental structure (40) to cover at least a portion of the dental structure (40); providing a hardenable dental article (10); and applying the hardenable dental article (10) to the dental structure (40) covered by the film (30).

Abstract: A securement device for securing a medical article is disclosed. The securement device comprises a base and a first securing portion comprising a strap that is movable between an open position and a closed position and a connector disposed on the base. The strap cooperates with the connector in the closed position to form an enclosure. The strap further comprises a curvilinear segment that projects inwardly into the enclosure in a convex orientation when the strap is in the closed position. Securement systems for securing medical articles and methods of securing at least a portion of a medical article to a patient are also provided.

Abstract: A medical article securement system for securing a medical article. The system can include a patch; a vertical wall comprising a first major surface positioned to face the medical article and a second major surface comprising a first mating surface of a mechanical fastener; and a flap comprising a first major surface positioned to face the medical article, at least a portion of the first major surface comprising a second mating surface of a mechanical fastener configured to engage the first mating surface of the vertical wall.

Abstract: A medical article securement system. The system can include a patch comprising a skin-contact adhesive. The system can further include at least one flap comprising a fixed end coupled to the patch, and a free end that is movable with respect to the patch and configured to secure at least a portion of the medical article to the patch. At least the free end of the flap can include a first major surface configured to face the medical article, at least a portion of the first major surface comprising a first mating surface of a mechanical fastener; and a second major surface, opposite the first major surface, configured to face away from the medical article, at least a portion of the second major surface comprising a second mating surface of the mechanical fastener configured to engage the first mating surface of the same flap, a different flap, or both.