Abstract: Compositions for treating a biofilm comprising viable microorganisms are provided. The compositions include a suspending medium, a bioactive glass comprising B2O3, and an effective amount of an antimicrobial compound selected from the group consisting of antimicrobial biguanide, quaternary ammonium compound, silver or copper deposited as a coating on the surface of the bioactive glass, and antimicrobial lipid component. Methods of treating a biofilm or a surface with the compositions are also provided.

Abstract: A securement system for securing a multi-lumen medical article. The system can include a patch, and a longitudinal flap. The flap can include a fixed proximal portion that is fixed with respect to the patch; a hinge; and a free distal portion movable via the hinge with respect to the patch and the fixed proximal portion of the flap between an open position and a closed position. The hinge can include a lateral width that is less than a lateral width of the patch and less than a lateral width of the flap. The hinge can be dimensioned to be received between two adjacent proximal tubings of the medical article, e.g., to provide a longitudinal stop to the medical article. The free distal portion can be configured to secure at least the multi-lumen joint of the medical article to the patch.

Abstract: A method of using hardenable dental articles. The method can include placing a film (30) onto a dental structure (40) to cover at least a portion of the dental structure (40); providing a hardenable dental article (10); and applying the hardenable dental article (10) to the dental structure (40) covered by the film (30).

Abstract: The present application is directed to a method of using a hardenable dental article. The method can include providing the hardenable dental article; applying the hardenable dental article to a dental structure; customizing the shape of the hardenable dental article; and at least partially curing the hardenable dental article.

Abstract: A graphic for use with medical article securement systems, medical article securement systems comprising a graphic, and methods of using same. The graphic can include a representation of an anatomical feature, such that the graphic provides a visual cue for coupling the medical article securement system to a subject in a desired orientation relative to the subject. Medical article securement systems comprising a graphic can be configured to be coupled to the subject and further configured to secure at least a portion of a medical article. Methods can include coupling the medical article securement system to the subject according to the graphic.

Abstract: An article for securing an object to a surface is provided. The article comprises a conformable backing having top and bottom major surfaces and a perimeter edge, an adhesive coated on at least a portion of the bottom major surface of the backing, and a self-supporting carrier releasably adhered to the top major surface of the backing, the carrier having spaced-apart first and second sections, each section having a central edge. The central edges define opposing borders of an object-conformable region of the backing. On opposite sides of the object-conformable region, the backing comprises two anchor regions. Also provided is a method of using the article to secure an object to the surface. The method comprises using at least one section of the carrier to conform the backing to at least a portion of the topological shape of the object to be secured to the surface.

Abstract: A medical article and methods of using same. The medical article can include a machine direction (MD) and a cross-machine direction (CMD); a support layer; and a viscoelastic layer. The viscoelastic layer can be coupled to the support layer, and the viscoelastic layer can be discontinuous in the MD and/or the CMD. The viscoelastic layer can recover at least 70% of its deformation after 48 hours at room temperature after being strained to 50% elongation, such that the medical article has a first tensile stiffness T1 at a first strain rate S1, and a second tensile stiffness T1 at a second strain rate Si. The ratio of S1/S2 can be at least 100, and the ratio of T1/T2 can be at least 1.5. The method can include wrapping the medical article around a body part; applying the first strain rate S1; and applying the second strain rate S2.

Abstract: The disclosed support device includes a contained cushioning element, which allowing for cleaning of the support device but limiting absorption of fluid into the cushioning element. The support device comprises a backing layer, a cushioning element, and a base layer. The backing layer comprises a first surface and second surface, opposite the first surface, wherein the backing layer is highly moisture vapor permeable and the first surface of the backing layer is liquid water impermeable. The cushioning element is positioned adjacent the second surface of the backing layer. The base layer comprises a first surface adjacent the cushioning element and a second surface, opposite the first surface of the cushioning element. The base layer is highly moisture vapor permeable. The base layer is entirely contiguous. The second surface of the base layer comprises an adhesive. The base layer and backing layer connect entirely around the cushioning element.

Abstract: A digital painting process provides computer-controlled finishing of dental articles. The process can selectively apply different materials over portions of a dental article in one or more layers to achieve a multi-chromatic finish having a variety of colors, finishes, and surface properties that closely match the appearance and function of human dentition.

Abstract: A medical sealant composition and method for coupling the medical article to skin using the medical sealant composition. The medical sealant composition can include an unsaturated rubber hydrocarbon having at least one hydrosilyation-crosslinkable functional group and a crosslinking agent having at least one SiH group per molecule. The medical sealant composition can cure at 35 degrees C. in less than 20 minutes. The method can include applying the composition to one or both of a medical article and skin when the composition is in an uncured state; applying the medical article to the skin; and allowing the composition to cure to form a sealant between the medical article and the skin.

Abstract: A securement assembly is disclosed that uses a combination of adhesive as well as mechanical fasteners for effectively securing a device to a surface. The securement assembly can be used to protect the surface from the device being secured. The securement assembly comprises an adhering element with a first mechanical fastener and a securing element with a second mechanical fastener, wherein the securing element can serve as both a cover for the adhesive on the adhering element while also providing the securement between the first mechanical fastener and second mechanical fastener.

Abstract: By capturing a highly detailed three-dimensional digital model of dentition, a suitable replacement dental article be fabricated with a combination of digitally-controlled reductive processes such as milling and digitally-controlled additive processes such as digital painting. A dental article so-manufactured can provide an aesthetically pleasing, multi-chromatic appearance that closely matches surrounding dentition.

Abstract: An article (100) for securing an object to a surface is provided. The article comprises a conformable backing (30) having top and bottom major surfaces and a perimeter edge, an adhesive (36) coated on at least a portion of the bottom major surface of the backing, and a self-supporting carrier (50) releasably adhered to the top major surface of the backing, the carrier having spaced-apart first and second sections (50), each section having a central edge. The central edges define opposing borders of an object-conformable region (37) of the backing. On opposite sides of the object-conformable region, the backing comprises two anchor regions. Also provided is a method of using the article to secure an object to the surface. The method comprises using at least one section of the carrier to conform the backing to at least a portion of the topological shape of the object to be secured to the surface.

Abstract: A hardenable dental article including a base and at least one outer surface extending from the base, wherein at least the base and the at least one outer surface of the hardenable dental article includes a hardenable dental material; and a multi-layer polymeric film conformable release liner in contact with at least a portion of the at least one outer surface.

Abstract: A method of making a biometric dental appliance. A first article can be formed of a first material based on a first digital surface representation having a desired outer shape of the dental appliance. A portion of the first article can then be removed to form an outer layer of the dental appliance comprising a cavity dimensioned to accommodate an inner layer. A second article can be formed by filling the cavity of the first article with a second material. The second material can have at least one different structural and/or optical property than the first material. The second article can be further processed, as desired. For example, a desired inner shape can be formed in the second article. Such a desired inner shape can be based on a second digital surface representation of a dental object configured to receive the dental appliance.

Abstract: A method of making a multi-chromatic dental appliance. A first article can be formed of a first material based on a first digital surface representation having a desired outer shape of the dental appliance. A portion of the first article can then be removed to form an outer layer of the dental appliance comprising a cavity dimensioned to accommodate an inner layer. A second article can be formed by filling the cavity of the first article with a second material. The second material can have at least one different optical property than the first material. The second article can be further processed, as desired. For example, a desired inner shape of the dental appliance can be formed in the second article. Such a desired inner shape can be based on a second digital surface representation of a dental object configured to receive the dental appliance.

Abstract: A securement device for securing a medical article is disclosed. The securement device comprises a base and a first securing portion comprising a strap that is movable between an open position and a closed position and a connector disposed on the base. The strap cooperates with the connector in the closed position to form an enclosure. The strap further comprises a curvilinear segment that projects inwardly into the enclosure in a convex orientation when the strap is in the closed position. Securement systems for securing medical articles and methods of securing at least a portion of a medical article to a patient are also provided.

Abstract: Curable dental compositions, dental articles, and methods of making or using such compositions or articles are described. In one embodiment, the curable dental restoration composition comprises a resin system comprising a free-radically polymerizable semi-crystalline resin having a molecular weight no greater than 3000 g/mole and at least 50 wt-% of nanocluster filler.

Abstract: A method of making a multilayer all-ceramic dental appliance. A first article can be formed of a first material based on a first digital surface representation having a desired outer shape of the dental appliance. A portion of the first article can be removed to form an outer layer comprising a cavity dimensioned to accommodate an inner layer. A second article can be formed by filling the cavity of the first article with a second material. The second article can be further processed, as desired. For example, a desired inner shape can be formed in the second article. Such a desired inner shape can be based on a second digital surface representation of a dental object configured to receive the dental appliance. At least one of the first article, the outer layer, and the second article can be fired, for example, while still being coupled to a support.