Abstract: A method of manufacturing an aluminum alloy wire includes: forming a rough drawing wire composed of an aluminum alloy containing aluminum, an additive element, and unavoidable impurities, the additive element including Si and Mg; obtaining an aluminum alloy wire by performing a treatment on the rough drawing wire, wherein the treatment includes at least one or more wire drawing treatments; forming a first solution treatment material by forming a solid solution of the aluminum and the additive element and then performing a quenching treatment on the solid solution, wherein the first solution treatment is performed directly before the last of the one or more wire drawing treatments is performed; a second solution treatment that forms a second solution treatment material by forming a solid solution of the aluminum and the additive element and then performing a quenching treatment on the solid solution.

Abstract: The present invention provides an antibody that recognizes peptides the N-terminals of which start from APP669 (collectively referred to as APP669-x) including the peptide APP669-711 related to an amyloid ? (A?); a method for measuring APP669-x using said antibody; and a sandwich immunoassay method that is capable of detecting and quantifying a polypeptide to be analyzed with a high sensitivity. An APP669-x N-terminal-recognizing monoclonal antibody that specifically recognizes an N-terminal of an APP669-x peptide. An immunoassay method that uses an APP669-x N-terminal-recognizing monoclonal antibody that specifically recognizes an N-terminal of an APP669-x peptide, and comprises reacting an APP669-x in a sample with the APP669-x N-terminal-recognizing monoclonal antibody to measure the APP669-x.

Abstract: An analysis method includes: preparing a sample containing peptide to be analyzed and an antioxidizing agent for preventing oxidation of methionine, the antioxidizing agent containing a protein, ionizing the peptide by laser desorption/ionization; and mass-separating and detecting the peptide that has been ionized.

Abstract: Provided is a method for measuring amyloid precursor protein (APP) cleavage peptides including amyloid beta (A?) peptides.

Abstract: Provided is a method for measuring a target polypeptide in a biological sample abundantly containing impurities by mass spectrometry.

Abstract: The present invention provides a specific combination of colon cancer markers based on statistical knowledge, which is capable of detecting a larger number of colon cancer patients in an earlier stage while maintaining high specificity. A multiplex colon cancer marker panel comprising a combination of five colon cancer markers of Carcinoembryonic antigen-related cell adhesion molecule 5, Carbohydrate antigen 19-9, Galectin-4, APEX nuclease and Actin-related protein 2. A method for analyzing colon cancer markers using multiplex colon cancer marker panel.

Abstract: An optical unit contains an optical element made of resin obtained by integrally forming a reflector in which a reflecting surface which reflects a light flux is formed on an outer peripheral side surface, and a flange extending in a direction orthogonal to the reflector to support the reflector; a rotary driving body which rotates the optical element; and a connecting device which connects the flange of the optical element to the rotary driving body, the optical element being capable of rotating around a rotational axis of the rotary driving body.

Abstract: An aluminum alloy wire that includes unavoidable impurities, the aluminum alloy wire including: aluminum; and an added element that includes at least Si and Mg. An exothermic peak of the aluminum alloy wire is in a temperature range of 200 to 300° C. on a differential scanning thermal analysis curve.

Abstract: A processing method for a volatile liquid using a pipette includes a low-volatility liquid suction step of sucking a low-volatility liquid that is less volatile than the volatile liquid through the suction/ejection port, an air suction step of sucking air through the suction/ejection port after the low-volatility liquid suction step, and a volatile liquid suction step of sucking the volatile liquid through the suction/ejection port after the air suction step.

Abstract: A mirror unit, a distance measurement device and a laser radar, and a mobile body and a fixed object having the mirror unit and the distance measurement device or the laser radar. The mirror unit includes a plurality of pairs of first reflecting surfaces and second reflecting surfaces inclined relative to a rotation axis, and extending in directions crossing each other. The mirror unit rotates about the rotation axis. In the mirror unit, a beam emitted from a light source is reflected on a first reflecting surface, and then reflected on a second reflecting surface paired with the first reflecting surface. The beam is scanned over an object with the rotation of the mirror unit. In the mirror unit, the first and second reflecting surfaces are formed, respectively, on first and second reflecting members which are combined to select an emission angle of a beam emitted from the mirror unit.

Abstract: Disclosed is a dry-blend mixture including (A) a specified metaxylylene group-containing polyamide and (B) a specified aliphatic polyamide, wherein a mass ratio ((A)/(B)) of the metaxylylene group-containing polyamide (A) and the aliphatic polyamide (B) is in a range of from 55/45 to 65/35.

Abstract: A bag making machine for manufacturing bags from an elongated film having print patterns repeatedly printed on one surface or two surfaces at a print pitch corresponding to a predetermined number of bags includes a processing unit configured to process the film for each length corresponding to the predetermined number of bags, a moving mechanism configured to move the processing unit, a shooting device, and an image processing device. The shooting device includes not less than one line sensor installed with a longitudinal direction of the line sensor extending along the widthwise direction of the film and obtains a linear image extending throughout a width of the film for each shooting operation. The image processing device sequentially receives the linear images from the shooting device and detects the actual length of the predetermined number of bags of the film based on an image extending throughout the width of the film.

Abstract: Provided are a biomarker for evaluating a cerebral A? accumulation state using amyloid precursor protein (APP)-derived A? and A?-like peptides in a living body-derived sample as an index, and a method for analysis thereof. A marker for determining a cerebral A? accumulation state, the marker comprising a combination of at least two ratios selected from the group consisting of: a ratio of A?1-39 (SEQ ID NO.: 1) level to A?1-42 (SEQ ID NO.: 3) level: A?1-39/A?1-42; a ratio of A?1-40 (SEQ ID NO.: 2) level to A?1-42 (SEQ ID NO.: 3) level: A?1-40/A?1-42; and a ratio of APP669-711 (SEQ ID NO.: 4) level to A?1-42 (SEQ ID NO.: 3) level: APP669-711/A?1-42, in a living body-derived sample.

Abstract: An optical unit contains an optical element made of resin obtained by integrally forming a reflector in which a reflecting surface which reflects a light flux is formed on an outer peripheral side surface, and a flange extending in a direction orthogonal to the reflector to support the reflector; a rotary driving body which rotates the optical element; and a connecting device which connects the flange of the optical element to the rotary driving body, the optical element being capable of rotating around a rotational axis of the rotary driving body.

Abstract: Provided are a biomarker for evaluating a cerebral A? accumulation state using an amyloid precursor protein (APP)-derived peptide in a living body-derived sample as an index, and a method for analysis thereof. A living body-derived sample derived from a test subject is measured, and at least one ratio selected from the group consisting of APP669-711/APP672-713 (A?1-42); APP672-709 (A?1-38)/APP672-713 (A?1-42); APP674-711 (A?3-40)/APP672-713 (A?1-42); APP672-710 (A?1-39)/APP672-713 (A?1-42); APP672-711 (A?1-40)/APP672-713 (A?1-42); and APP672-711 (OxA?1-40)/APP672-713 (A?1-42) is calculated, and when each of the ratios of the test subject is higher than each of standard levels which are ratios of a person having normal cognitive function NC? who is negative for cerebral A? accumulation, an accumulation amount of cerebral A? of the test subject is determined as larger than an accumulation amount of cerebral A? of the person having normal cognitive function NC?.

Abstract: A mirror unit, a distance measurement device and a laser radar, and a mobile body and a fixed object having the mirror unit and the distance measurement device or the laser radar. The mirror unit includes a plurality of pairs of first reflecting surfaces and second reflecting surfaces inclined relative to a rotation axis, and extending in directions crossing each other. The mirror unit rotates about the rotation axis. In the mirror unit, a beam emitted from a light source is reflected on a first reflecting surface, and then reflected on a second reflecting surface paired with the first reflecting surface. The beam is scanned over an object with the rotation of the mirror unit. In the mirror unit, the first and second reflecting surfaces are formed, respectively, on first and second reflecting members which are combined to select an emission angle of a beam emitted from the mirror unit.

Abstract: The optical element is a long optical element obtained by detaching a long main body part connected to a runner part via a gate part including an optical part from the gate part and chipping the detached main body, the optical part including at least a first optical surface to allow light to pass there through or to reflect light. The first optical surface has a curved surface that is curved on the short direction at least at the longitudinal end, while the first edge of the first optical surface side on the end surface of gate part side in the main body part is curved according to the curved surface example of the first optical surface. The boundary surface between the main body part and the gate part is formed so as to be narrower than the end surface of the gate part side of the main body part.

Abstract: Provided is a method for measuring a target polypeptide in a biological sample abundantly containing impurities by mass spectrometry.

Abstract: Provided is a method for measuring amyloid precursor protein (APP) cleavage peptides including amyloid beta (A?) peptides.

Abstract: The optical element is a long optical element obtained by detaching a long main body part connected to a runner part via a gate part including an optical part from the gate part and chipping the detached main body, the optical part including at least a first optical surface to allow light to pass there through or to reflect light. The first optical surface has a curved surface that is curved on the short direction at least at the longitudinal end, while the first edge of the first optical surface side on the end surface of gate part side in the main body part is curved according to the curved surface example of the first optical surface. The boundary surface between the main body part and the gate part is formed so as to be narrower than the end surface of the gate part side of the main body part.