Patents by Inventor Naoki Kaneko
Naoki Kaneko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20160003830Abstract: The present invention provides a specific combination of colon cancer markers based on statistical knowledge, which is capable of detecting a larger number of colon cancer patients in an earlier stage while maintaining high specificity. A multiplex colon cancer marker panel comprising a combination of five colon cancer markers of Carcinoembryonic antigen-related cell adhesion molecule 5, Carbohydrate antigen 19-9, Galectin-4, APEX nuclease and Actin-related protein 2. A method for analyzing colon cancer markers using multiplex colon cancer marker panel.Type: ApplicationFiled: September 11, 2015Publication date: January 7, 2016Inventors: Makoto Watanabe, Eiichi Matsuo, Naoki Kaneko, Toshiya Matsubara, Osamu Nishimura, Masaki Mori, Hideo Matsuda, Shigeto Seno, Ichiro Takemasa
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Publication number: 20150177263Abstract: Problems to be Solved The present invention provides an affinity support capable of trapping a substance by cooperative binding that is less likely to Surface of cause dissociation even when the substance is a molecule other than an antibody, and a trapping method using the same. Means to Solve the Problems A method of trapping a substance comprising the step of contacting an objective to be trapped with an affinity support comprising a support, a spacer bound to the support and an affinity substance bound to the spacer, so as to bind the objective to be trapped to the affinity substance, wherein each one of the objective to be trapped has a plural of affinity sites and the affinity substance binds to at least two of the affinity sites simultaneously.Type: ApplicationFiled: January 20, 2015Publication date: June 25, 2015Applicant: Shimadzu CorporationInventors: Naoki Kaneko, Takayuki Yoshimori
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Patent number: 8960779Abstract: An opening portion is formed at a specified portion of a roof gusset which covers part of a panel joint portion from below. A pair of center-pillar side joint portions is provided at an outward end portion of the roof gusset, which is joined to a center pillar directly or via another panel member. A pair of first high-rigidity portions is provided at specified portions of the roof gusset which overlap the opening portion in a vehicle width direction and overlap the center-pillar joint portions in the vehicle longitudinal direction, respectively. A second high-rigidity portion is provided at an inward end portion of the roof gusset to extend in the vehicle longitudinal direction.Type: GrantFiled: July 19, 2013Date of Patent: February 24, 2015Assignee: Mazda Motor CorporationInventors: Yoshikazu Nishimura, Kei Ikeda, Kazuya Fukutani, Naoki Kaneko, Noboru Yoshii
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Publication number: 20150044691Abstract: The present invention provides a blood marker for renal cancer, more specifically, a blood marker that can be practically used for clinical diagnosis of renal cancer. The present invention also provides a blood marker that can be practically used for follow-up after treatment such as surgery and during treatment such as medication for renal cancer. A blood marker for renal cancer selected from the group consisting of Galectin-1, Galectin-3, and ?-enolase. Galectin-1 and/or Galectin-3 as a blood marker for renal cancer for use in an examination performed before diagnostic imaging. ?-Enolase as a blood marker for renal cancer for use in monitoring during and/or after treatment for renal cancer.Type: ApplicationFiled: October 24, 2014Publication date: February 12, 2015Inventors: Eiichi Matsuo, Naoki Kaneko, Makoto Watanabe, Osamu Nishimura, Noboru Okamura, Akinobu Gotoh
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Patent number: 8851556Abstract: A center pillar includes a first reinforcement panel which is arranged between an outer panel and an inner panel, comprises a bottom wall portion, both-side vertical wall portions extending in a vehicle width direction from the bottom wall portion, and both-side flange portions, and has a cross section formed in substantially a hat shape. A second reinforcement panel comprising a bottom wall portion and both-side vertical wall portions and having a cross section formed in substantially a U shape is arranged inside the first reinforcement panel. The second reinforcement panel is joined to the first reinforcement panel such that only the bottom wall portion and one of the both-side vertical wall portions are joined to the bottom wall portion and one of the both-side vertical wall portions, respectively.Type: GrantFiled: July 10, 2013Date of Patent: October 7, 2014Assignee: Mazda Motor CorporationInventors: Yoshikazu Nishimura, Kei Ikeda, Kazuya Fukutani, Naoki Kaneko, Noboru Yoshii
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Patent number: 8852471Abstract: A die having a plurality of cavities and a temperature sensor for acquiring a temperature value in which the number of the cavities is larger than that of electrothermal conversion elements. When viewed from a direction perpendicular to the surface of a parting line, all cavities and a temperature sensor are arranged in a region occupied by the electrothermal conversion elements. Interval between the outlines of the cavities is smaller than the minimum interval between the outline of the cavity and the electrothermal conversion element, and the shortest distance between the electrothermal conversion element and the temperature measuring portion of a temperature measuring element is shorter than the minimum interval between the outline of the cavity and the electrothermal conversion element.Type: GrantFiled: July 19, 2007Date of Patent: October 7, 2014Assignee: Konica Minolta Opto, Inc.Inventors: Atsushi Naito, Naoki Kaneko, Akihiko Matsumoto, Kanji Sekihara, Shinichiro Hara
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Publication number: 20140028056Abstract: A center pillar includes a first reinforcement panel which is arranged between an outer panel and an inner panel, comprises a bottom wall portion, both-side vertical wall portions extending in a vehicle width direction from the bottom wall portion, and both-side flange portions, and has a cross section formed in substantially a hat shape. A second reinforcement panel comprising a bottom wall portion and both-side vertical wall portions and having a cross section formed in substantially a U shape is arranged inside the first reinforcement panel. The second reinforcement panel is joined to the first reinforcement panel such that only the bottom wall portion and one of the both-side vertical wall portions are joined to the bottom wall portion and one of the both-side vertical wall portions, respectively.Type: ApplicationFiled: July 10, 2013Publication date: January 30, 2014Inventors: Yoshikazu NISHIMURA, Kei IKEDA, Kazuya FUKUTANI, Naoki KANEKO, Noboru YOSHII
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Publication number: 20140028057Abstract: An opening portion is formed at a specified portion of a roof gusset which covers part of a panel joint portion from below. A pair of center-pillar side joint portions is provided at an outward end portion of the roof gusset, which is joined to a center pillar directly or via another panel member. A pair of first high-rigidity portions is provided at specified portions of the roof gusset which overlap the opening portion in a vehicle width direction and overlap the center-pillar joint portions in the vehicle longitudinal direction, respectively. A second high-rigidity portion is provided at an inward end portion of the roof gusset to extend in the vehicle longitudinal direction.Type: ApplicationFiled: July 19, 2013Publication date: January 30, 2014Inventors: Yoshikazu NISHIMURA, Kei IKEDA, Kazuya FUKUTANI, Naoki KANEKO, Noboru YOSHII
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Patent number: 8427726Abstract: Provided are a resinous reflecting optical element that achieves high mirror surface precision by mitigating the warping effects associated with contraction during resin hardening and suppressing the distortion of a mirror surface that results from resistance to mold release, and a scanning optical device that uses said reflecting optical element.Type: GrantFiled: February 4, 2010Date of Patent: April 23, 2013Assignee: Konica Minolta Opto, Inc.Inventors: Shinichiro Hara, Naoki Kaneko, Hiroshi Takagi
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Publication number: 20130071864Abstract: The present invention provides a tumor screening marker that can be actually used in clinical practice to detect colorectal cancer, and a tumor progression marker that can complement CEA or CA19-9. Vitronectin for use as a tumor progression marker, a tumor screening marker or a prognostic prediction marker for colorectal cancer. A method of analyzing a vitronectin concentration in a collected blood sample. In the method, a measured value of vitronectin and a reference value of vitronectin are compared. Vitronectin is preferably used in combination with existing marker for colorectal cancer such as carcinoembryonic antigen and CA19-9.Type: ApplicationFiled: January 28, 2011Publication date: March 21, 2013Inventors: Makoto Watanabe, Ei-Ichi Matsuo, Naoki Kaneko, Toshiya Matsubara, Masaki Mori, Ichiro Takemasa, Osamu Nishimura
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Publication number: 20130065258Abstract: The present invention provides a tumor screening marker that can be actually used in clinical practice to detect colorectal cancer, and a tumor progression marker that can complement CEA or CA19-9. Galectin-1 used as a tumor screening marker or a tumor progression marker for colorectal cancer. Galectin-3 used as a tumor screening marker. Galectin-4 used as a tumor progression marker, a tumor screening marker, or a prognostic prediction marker for colorectal cancer. A method of analyzing the galectin concentration in a collected blood sample using the galectin. A colorectal cancer marker detection kit comprising a detection antibody selected from the group consisting of a fluorescently labeled galectin-1 antibody, a fluorescently labeled galectin-3 antibody, and a fluorescently labeled galectin-4 antibody.Type: ApplicationFiled: January 28, 2011Publication date: March 14, 2013Inventors: Makoto Watanabe, Ei-ichi Matsuo, Naoki Kaneko, Toshiya Matsubara, Osamu Nishimura, Masaki Mori, Ichiro Takemasa
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Patent number: 8346034Abstract: An optical selector includes: an optical waveguide which includes a first light guide section having a first refractive index, a second light guide section having a second refractive index provided to the side of and along the entire circumference of the first light guide section, and a reflector provided at opposing positions on both surfaces of each of the first and second light guide sections while exposing the outer circumferential surface of the second light guide section; a single or plurality of LDs that are placed on the outer circumference of the optical waveguide, and emit light toward the first light guide section; and a single or plurality of photodetectors that are placed on the outer circumference of the optical waveguide, and receive light emitted from the outer circumference of the optical waveguide.Type: GrantFiled: May 27, 2008Date of Patent: January 1, 2013Assignee: Sony CorporationInventors: Ken Hayakawa, Kazuo Haraoka, Masaaki Hattori, Naoki Kaneko, Tetsujiro Kondo, Hidehiko Sekizawa, Nozomu Ozaki, Seiji Wada, Toshiyuki Sekiya, Shinji Sangawa
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Patent number: 8335408Abstract: In the sending and receiving of a signal through an optical waveguide, an unknown substrate connected to the optical waveguide can be recognized.Type: GrantFiled: October 7, 2008Date of Patent: December 18, 2012Assignee: Sony CorporationInventors: Toshiyuki Sekiya, Ken Hayakawa, Kazuo Haraoka, Masaaki Hattori, Naoki Kaneko, Tetsujiro Kondo
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Patent number: 8318201Abstract: (wherein Y1 and Y2 may be the same or different and each represents a hydrogen atom, halogen or lower alkyl; and Z and A may be the same or different and each represents substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl) The present invention provides, for example, a method for stabilization of a diarylvinylene compound such as a compound represented by the above formula (I) or the like, or a pharmaceutically acceptable salt thereof in a solid formulation containing the diarylvinylene compound or the pharmaceutically acceptable salt thereof, which comprises allowing an inorganic substance and/or a colorant to exist in the solid formulation, and the like.Type: GrantFiled: September 29, 2004Date of Patent: November 27, 2012Assignee: Kyowa Hakko Kirin Co., Ltd.Inventors: Akihiro Uchida, Yasuhiro Ishikawa, Yasuhiko Ueno, Kiichiro Kaji, Masaharu Aimoto, Naoki Kaneko
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Publication number: 20120187588Abstract: A device for manufacturing resin molded articles for use in optical elements. Said device is provided with a first molding die which is fixed in place; a second molding die, being movable, which has, on a molding die surface of a cavity, a transfer surface for transferring an optical surface to a melted resin injected into the cavity; a nozzle for injecting a fluid under pressure into the melted resin injected into the cavity, thereby forming a void inside said melted resin; and an ejector pin that is provided in the second molding die, protruding from the molding surface thereof, to release a base material from the molding surface.Type: ApplicationFiled: September 6, 2010Publication date: July 26, 2012Inventors: Hiroshi Takagi, Naoki Kaneko, Yasuhiro Matsumoto, Shinichiro Hara
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Publication number: 20120008184Abstract: Provided are a resinous reflecting optical element that achieves high mirror surface precision by mitigating the warping effects associated with contraction during resin hardening and suppressing the distortion of a mirror surface that results from resistance to mold release, and a scanning optical device that uses said reflecting optical element.Type: ApplicationFiled: February 4, 2010Publication date: January 12, 2012Inventors: Shinichiro Hara, Naoki Kaneko, Hiroshi Takagi
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Patent number: 8055965Abstract: A semiconductor integrated circuit includes: a plurality of scan flip-flops configured to form a scan chain in a scan test; and a plurality of clock gating circuits connected between a clock input and corresponding portions of the plurality of scan flip-flops, respectively. The plurality of clock gating circuits are connected in serial to form a chain and gating setting data is inputted in serial through the chain connection. Each of the plurality of clock gating circuits controls a connection between the clock input and a corresponding portion of the plurality of scan flip-flops based on the gating setting data.Type: GrantFiled: May 26, 2010Date of Patent: November 8, 2011Assignee: Renesas Electronics CorporationInventor: Naoki Kaneko
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Patent number: 7891704Abstract: A side airbag device provided at a seat back of a seat, comprises an airbag including a chest-abdomen protection portion to protect a chest and abdomen of an occupant seated and a waist protection portion to protect a waist of the occupant, and an inflator to supply gas to the airbag for an inflation at a vehicle side crash or a vehicle turnover, wherein the portions are partitioned by a partition portion that at least extends substantially rearward from an front edge of the airbag, and a recess is provided at an upper portion of the chest-abdomen protection portion. Accordingly, a whole part of side body including the chest, abdomen and waist can be properly protected regardless of the body size of the occupant, even for the occupant having the relatively small body size.Type: GrantFiled: June 12, 2007Date of Patent: February 22, 2011Assignee: Mazda Motor CorporationInventors: Seigo Taguchi, Naoki Kaneko, Masaki Motoki, Kazuya Fukutani
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Patent number: 7889957Abstract: An optical selector switch contains an optical waveguide that includes a first optical waveguide portion having a first light-transmissivity, a second optical waveguide portion having a second light-transmissivity, reflecting members that reflect light, and a light-dividing device that reflects and transmits light; at least one light-emitting unit that emits the light toward the first optical waveguide portion of the optical waveguide; and at least one light-receiving unit that receives the light which is incident to the first optical waveguide portion of the optical waveguide from the light-emitting unit, based on a directivity due to an angle of the incident light to the first optical waveguide portion of the optical waveguide, wherein the incident light to the first optical waveguide portion is emitted radially toward the circumference of the second optical waveguide portion of the optical waveguide.Type: GrantFiled: March 4, 2009Date of Patent: February 15, 2011Assignee: Sony CorporationInventors: Hidehiko Ogasawara, Nozomu Ozaki, Seiji Wada, Toshiyuki Sekiya, Ken Hayakawa, Kazuo Haraoka, Shinji Sangawa, Masaaki Hattori, Naoki Kaneko, Tetsujiro Kondo
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Publication number: 20100306607Abstract: A semiconductor integrated circuit includes: a plurality of scan flip-flops configured to form a scan chain in a scan test; and a plurality of clock gating circuits connected between a clock input and corresponding portions of the plurality of scan flip-flops, respectively. The plurality of clock gating circuits are connected in serial to form a chain and gating setting data is inputted in serial through the chain connection. Each of the plurality of clock gating circuits controls a connection between the clock input and a corresponding portion of the plurality of scan flip-flops based on the gating setting data.Type: ApplicationFiled: May 26, 2010Publication date: December 2, 2010Applicant: Renesas Electronics CorporationInventor: Naoki Kaneko