Abstract: Disclosed are a variety of amphoteric ester sulfonates, including 3-(N,N-dimethyl-cocoylpropylammonio-1-yl)-2-hydroxypropanesulfonate. These amphoteric ester sulfonates can be advantageously prepared in high yield and purity by a two-step chemoenzymatic process, and have excellent surfactant properties.

Abstract: A hand-held controller includes a user-input surface, a grip coupled to the user-input surface, and a cage coupled to the user-input surface at two points without the grip interposed between the user-input surface and the cage. The hand-held controller includes may further include a plurality of illumination sources on an outer surface of the cage.

Abstract: A virtual-reality system includes a head-mounted display (HMD), a forward-looking camera coupled to the HMD and a hand-held controller communicatively coupleable to the HMD. The hand-held controller includes a first user-input key, a grip, and an outward-facing surface coupled to the grip. The outward-facing surface includes a plurality of illumination sources which provide light that is detectable by the camera for sensing a position of the controller based on a user motion.

Abstract: The present invention provides compositions utilizing a zwitterionic ester ammonioalkanoate surfactant according to Formula 1 and an ingredient selected from the group consisting a surfactant other than said zwitterionic ester ammonioalkanoate surfactant, emulsifiers, conditioning agents, emollients, moisturizers, humectants, thickeners, lubricants, chelating agents, fillers, binding agents, anti-oxidants, preservatives, active ingredients, fragrances, dyes, buffering agents, exfoliates, pH adjusters, inorganic salts, solvents, viscosity controlling agents and opacifying agents, wherein the composition is substantially free of alkylamidoamine and aminoalkylamine.

Abstract: Disclosed are a variety of amphoteric compounds having a heterocyclic quaternary nitrogen group. The heterocycle includes pyridines, piperidines, and pyrrolidines, and is linked to the hydrophobe via either an amide or an ester linkage. These heterocyclic amphoteric compounds can be advantageously prepared in high yield and purity by a two-step chemoenzymatic process, and have excellent surfactant properties.

Abstract: A hand-held controller includes a user-input surface, a grip coupled to the user-input surface, and a cage coupled to the user-input surface at two points without the grip interposed between the user-input surface and the cage. The hand-held controller includes may further include a plurality of illumination sources on an outer surface of the cage.

Abstract: A surgical spray instrument is disclosed comprising a main body connectable to a transfer tube; a propellant actuator for selectively releasing propellant from the main body and along the transfer tube and out through a distal end thereof. An ion emitter is arranged along the tube, the ion emitter having an ion emission zone. This enables the directed and concentrated delivery of therapeutic, pharmacological and diagnostic agents to tissues inside or outside of the body. There is further disclosed a surgical assembly for enabling uniform deposition of a particulate material to a surface of an intracorporeal cavity of a patient. The surgical assembly comprises an ion emitter; a dispenser having an outlet locatable within the cavity and for dispensing the particulate material therefrom, and a processor for determining a location of the ion emission zone of the ion emitter in dependence upon the position of the outlet of the distributor within the cavity to provide for the uniform deposition.

Abstract: This disclosure describes a low temperature process for the preparation of dimethyl amines from nitriles via reductive amination. In some embodiments, the process proceeds under mild conditions with aqeuous dimethylamine and show an unexpected rate acceleration by the inclusion of an acid addition salt of the dimethylamine.

Abstract: A system and methods for promoting fusion across an intervertebral disc space, the system including a plurality of spinal fusion implants wherein the maximum length of an individual implant less than the maximum depth dimension of the endplate of the inferior vertebral body into which the system of spinal fusion implants is inserted.

Abstract: A surgical access port and assembly are disclosed for providing access for a medical instrument into an intracorporeal cavity of a patient undergoing surgery. The access port comprises a cannula and a first passage which extends along the cannula and along which a medical instrument is arranged to pass, the passage comprising a first entrance portion disposed at a proximal region the of the cannula and a first exit portion disposed at a distal region of the cannula. The cannula further comprises a second passage which extends along the cannula and along which an electrode is arranged to pass, the second passage comprising a second entrance portion disposed at a proximal region of the cannula and a second exit portion disposed at a distal region of the cannula.

Abstract: There is provided a handheld controller for a virtual reality system. The hand-held controller includes a user-input surface and a grip coupled to the user-input surface. The user-input surface has a first user-input key. The hand-held controller further includes a cage coupled to the user-input surface. The cage includes a plurality of illumination sources on an outer surface of the cage, which provide light to be detected by a camera for sensing a position of the controller based on a user motion.

Abstract: A surgical instrument is disclosed which comprises a surgical device actuatable for performing a surgical procedure, the device having an electrically conductive portion, and an ion-generating electrode integrally arranged with respect to the surgical device, the ion-generating electrode having an ion emission zone. The ion emission zone of the ion-generating electrode and the electrically conductive portion of the surgical device are moveable relative to each-other between a first position and a second position.

Abstract: Disclosed are a variety of amphoteric compounds containing a quaternary nitrogen group, a covalently bound counterion, and an ester or amide group. These amphoteric compounds can be advantageously prepared via a chemoenzymatic green process, and exhibit good surfactant properties.

Abstract: The present invention provides compositions utilizing a first zwitterionic ammonio-alkanamide and/or zwitterionic ammonio-alkanoate surfactant according to Formula 1 and an ingredient selected from the group consisting a surfactant other than the first zwitterionic surfactant, emulsifiers, conditioning agents, emollients, moisturizers, humectants, thickeners, lubricants, chelating agents, fillers, binding agents, anti-oxidants, preservatives, active ingredients, fragrances, dyes, buffering agents, exfoliates, pH adjusters, inorganic salts, solvents, viscosity controlling agents and opacifying agents, wherein the composition is substantially free of alkylamidoamine and aminoalkylamine.

Abstract: Disclosed are a variety of amphoteric compounds having a heterocyclic quaternary nitrogen group. The heterocycle includes pyridines, piperidines, and pyrrolidines, and is linked to the hydrophobe via either an amide or an ester linkage. These hetereocyclic amphoteric compounds can be advantageously prepared in high yield and purity by a two-step chemoenzymatic process, and have excellent surfactant properties.

Abstract: Disclosed are a variety of amphoteric compounds having a heterocyclic quaternary nitrogen group. The heterocycle includes pyridines, piperidines, and pyrrolidines, and is linked to the hydrophobe via either an amide or an ester linkage. These heterocyclic amphoteric compounds can be advantageously prepared in high yield and purity by a two-step chemoenzymatic process, and have excellent surfactant properties.

Abstract: Esters of O-substituted hydroxy carboxylic acids are provided having Formula 1, or 2, or both Formulas 1 and 2: wherein R and R1 are independently selected from the group consisting of substituted and unsubstituted, branched- and straight-chain, saturated, unsaturated, and polyunsaturated C1-C22 alkyl, substituted and unsubstituted C3-C8 cycloalkyl, substituted and unsubstituted C6-C20 carbocyclic aryl, and substituted and unsubstituted C4-C20 heterocyclic; wherein the heteroatoms are selected from sulfur, nitrogen, and oxygen; and wherein n is 1-6. Process of producing esters of O-substituted hydroxy carboxylic acids are also provided.

Abstract: This disclosure describes a low temperature process for the preparation of dimethyl amines from nitriles via reductive amination. In some embodiments, the process proceeds under mild conditions with aqeuous dimethylamine and show an unexpected rate acceleration by the inclusion of an acid addition salt of the dimethylamine.

Abstract: There is provided a handheld controller for a virtual reality system. The hand-held controller includes a user-input surface and a grip coupled to the user-input surface. The user-input surface has a first user-input key. The hand-held controller further includes a cage coupled to the user-input surface. The cage includes a plurality of illumination sources on an outer surface of the cage, which provide light to be detected by a camera for sensing a position of the controller based on a user motion.

Abstract: A virtual-reality system includes a head-mounted display (HMD), a forward-looking camera coupled to the HMD and a hand-held controller communicatively coupleable to the HMD. The hand-held controller includes a first user-input key, a grip, and an outward-facing surface coupled to the grip. The outward-facing surface includes a plurality of illumination sources which provide light that is detectable by the camera for sensing a position of the controller based on a user motion.