Abstract: The present invention relates to consensus nucleotide and protein sequences for HIV-1 Clade A antigens, and to nucleotide and protein sequences for Clade A antigens from circulating HIV-1 field isolates wherein the antigen sequences are closely related to the these consensus sequences. In a preferred embodiment, the present invention relates to HIV-1 Clade A transgenes that are derived from such sequences, and that encode either HIV-1 Clade A Gag, Pol (RT and Int), and Nef (referred to as “GRIN”), HIV-1 Clade A Gag, RT, and Nef (referred to as (“GRN”), or HIV-1 Clade A Env. The invention also relates to vectors containing such transgenes, including in preferred embodiment, adenovirus vectors containing such transgenes.

Abstract: A fastener having a shank with a moveable portion that improves insertion of the fastener into an aperture, as well as improves the retention of the fastener within the aperture and the resistance of the fastener to extraction.

Abstract: A retainer assembly comprises a pin including a head and a flange defining a groove therebetween for engaging a first panel. A grommet includes a collar encompassing the pin and flexible arms extending from a hinge point at the collar. The assembly is initially in a shipped position wherein the flexible arms extend along the pin and are maintained in a pocket between ribs of the pin. The pin is inserted through a second panel until the collar engages the second panel. The grommet bends at the hinge points allowing the flexible arms to slide out of the pocket and adjustable engage the pin and the second panel until the second panel is maintained in position by the flexible arms, collar, and flange. Upon removing the assembly from the panels, the grommet adjusts back to the shipped position and the assembly is ready for reuse.

Abstract: A control assembly (10) for controlling the actuation of two clutch packs (50, 52) includes a motor (12) for driving an annular gear wheel (24). Radial pins (30) project from the gear wheel to engage concentric pistons (34, 36) arranged for linear movement relative to one another along the axis of rotation of the gear wheel. Each piston includes slots (40) which define cam surfaces for engagement by the drive pins. Rotation of the gear wheel in first direction causes the pins to drive against cam surfaces on the inner piston, to drive the inner piston towards the inner clutch. Rotation of the gear wheel in the opposite direction causes the pins to drive against cam surfaces on the outer piston, to drive the outer piston towards the outer clutch.

Abstract: Various configurations of twin layshaft gear transmission are disclosed, typically having a large degree of common parts between single and dual clutch variants. In one embodiment reverse ratio is provided via an independent compound idler and is driven from a driving gear also associated with a forward speed ratio.

Abstract: A fastener having a shank with a moveable portion that improves insertion of the fastener into an aperture, as well as improves the retention of the fastener within the aperture and the resistance of the fastener to extraction.

Abstract: A fastener assembly wherein the fastener is limited to one orientation for insertion into a receiving member. The fastener has a D-shape cross section defined by the outer extent of the fastener.

Abstract: The present invention relates to consensus nucleotide and protein sequences for HIV-1 Clade A antigens, and to nucleotide and protein sequences for Clade A antigens from circulating HIV-1 field isolates wherein the antigen sequences are closely related to the these consensus sequences. In a preferred embodiment, the present invention relates to HIV-1 Clade A transgenes that are derived from such sequences, and that encode either HIV-1 Clade A Gag, Pol (RT and Int), and Nef (referred to as “GRIN”), HIV-1 Clade A Gag, RT, and Nef (referred to as (“GRN”), or HIV-1 Clade A Env. The invention also relates to vectors containing such transgenes, including in preferred embodiment, adenovirus vectors containing such transgenes.

Abstract: The present application relates to a filtration system (1) having at least one flexible filter (9) and cleaning apparatus (25) for projecting a flow of fluid onto the at least one flexible filter. The fluid to be filtered passes through the at least cone flexible filter (9) and causes the at least one flexible filter (9) to be deflected in a first direction. The flow of fluid projected onto the at least one flexible filter (9) from the cleaning apparatus (25) causes the at least one flexible filter (9) to be deflected in a second direction. The first and second directions are substantially opposite to each other. The present invention further relates to a filtration system (1) for filtering particulates from a liquid. The filtration system has a sealed vessel (2) suitable for supporting a pressure less than atmospheric pressure. A filter (9) is provided for filtering particulates from the liquid. The application also relates to a method of filtering fluid.

Abstract: A filter unit for filtering particulates and other foreign matter from a water supply, comprising a filtering chamber. At least a portion of an exterior of the filtering chamber being provided with filtering chamber in use. The mesh being sized to filter particulates and other foreign matter from the water. The filter unit further comprising an outlet through which filtered water exits the filter unit, and a rotatable member located within the filtering chamber, the rotatable member having at least one outlet spaced from an internal face of a mesh. The axis of rotation of the rotatable member being such that the at least one outlet traverses at least a substantial portion of the internal face of a mesh.

Abstract: The present invention provides a fastener mounting clip for use in securing a fastener to sheet material having a bore hole formed therein. The fastener mounting clip is preferably formed of a single sheet of thin spring steel. The mounting clip includes a rectilinear planar surface having opposing retainer arms extending beneath its outer edge at obtuse angles. The retaining arms are resiliently flexible and compress and expand during insertion wherein a top end of the retaining arm abuts against the sheet material when the fastener mounting clip is fully seated within the bore hole. The planar surface includes support tabs for supporting the planar surface in the plane of the sheet material and also includes a recessed aperture for receiving and retaining a fastener therein.

Abstract: The present invention provides a fastener mounting clip for use in securing a fastener to sheet material having a bore hole formed therein. The fastener mounting clip is preferably formed of a single sheet of thin spring steel. The mounting clip includes a rectilinear planar surface having opposing retainer arms extending beneath its outer edge at obtuse angles. The retaining arms are resiliently flexible and compress and expand during insertion wherein a top end of the retaining arm abuts against the sheet material when the fastener mounting clip is fully seated within the bore hole. The planar surface includes support tabs for supporting the planar surface in the plane of the sheet material and also includes a recessed aperture for receiving and retaining a fastener therein.

Abstract: A one piece fastener capable of being secured to a substrate member and having an uncoupled position and a coupled position. The fastener includes an outer member defining a cavity and an inner member integrally formed with said outer member. The inner member is disposed in the cavity of the outer member wherein the outer member is moved along a longitudinal axis from an uncoupled position to a coupled position relative to said inner member. The inner member includes living hinges permitting the outer and inner members to move relative to one another. The fastener also includes at least one locking mechanism for locking the fastener in a coupled position. The outer member includes a head and recess for receiving a portion of the inner member in the coupled position and permitting the fastener to be released from the coupled position and reused.

Abstract: The present invention provides a fastener mounting clip for use in securing a fastener to sheet material having a bore hole formed therein. The fastener mounting clip is preferably formed of a single sheet of thin spring steel. The mounting clip includes a rectilinear planar surface having opposing guide arms and opposing retainer arms extending beneath its outer edge at obtuse angles. The guide arms are operative to minimize the insertion force required for seating the fastener mounting clip in the bore hole formed in the sheet material. The retaining arms are resiliently flexible and compress and expand during insertion wherein a top end of the retaining arm abuts against the sheet material when the fastener mounting clip is fully seated within the bore hole. The planar surface includes support tabs for supporting the planar surface in the plane of the sheet material and also includes a recessed aperture for receiving and retaining a fastener therein.

Abstract: A filter unit for filtering particulates and other foreign matter from a fluid supply, comprising a filtering chamber. At least a portion of an exterior of the filtering chamber being provided with a mesh through which fluid may enter the filtering chamber in use. The mesh being sized to filter particulates and other foreign matter from the fluid. The filter unit further comprising an outlet through which filtered fluid exits the filter unit, and a rotatable member located within the filtering chamber, the rotatable member having at least one outlet spaced from an internal face of a mesh. The axis of rotation of the rotatable member being such that the at least one outlet traverses at least a substantial portion of the internal face of a mesh.

Abstract: A filter unit for filtering particulates and other foreign matter from a water supply, comprising a filtering chamber. At least a portion of an exterior of the filtering chamber being provided with filtering chamber in use. The mesh being sized to filter particulates and other foreign matter from the water. The filter unit further comprising an outlet through which filtered water exits the filter unit, and a rotatable member located within the filtering chamber, the rotatable member having at least one outlet spaced from an internal face of a mesh. The axis of rotation of the rotatable member being such that the at least one outlet traverses at least a substantial portion of the internal face of a mesh.

Abstract: The present invention provides a fastener mounting clip for use in securing a fastener to sheet material having a bore hole formed therein. The fastener mounting clip is preferably formed of a single sheet of thin spring steel. The mounting clip includes a rectilinear planar surface having opposing guide arms and opposing retainer arms extending beneath its outer edge at obtuse angles. The guide arms are operative to minimize the insertion force required for seating the fastener mounting clip in the bore hole formed in the sheet material. The retaining arms are resiliently flexible and compress and expand during insertion wherein a top end of the retaining arm abuts against the sheet material when the fastener mounting clip is fully seated within the bore hole. The planar surface includes support tabs for supporting the planar surface in the plane of the sheet material and also includes a recessed aperture for receiving and retaining a fastener therein.

Abstract: A fastener for coupling a trim panel to a support member includes a mounting grommet with a funnel-shaped receiver communicating with an aperture for receiving one end of a fastener pin having a plurality of spaced annular ratcheting grooves formed thereon. The opposite or second end of the pin includes a pointed end with a pair of resilient locking arms, which extend divergently outwardly and away from an apex of the second end of the pin at an acute angle and at a spacing of about 180°, for insertion into an aperture of a support structure. Interposed between the first and second ends of the fastening pin is a resilient, generally cup-shaped seal which engages a surface of the support structure opposite the locking arms for providing a seal surrounding the aperture in the support structure to which the fastening pin is inserted. The grommet includes an annular slot defined by a collar on one side and a shoulder of the funnel-shaped receiver on the other.

Abstract: A retainer which will secure a wire bundle to a panel like the retainer is hinged U shaped portions which can be releasably closed to clamp the bundle between deflectable pair of spreadable wings.