Abstract: The invention relates to an antibody which binds to chondroitin sulfate proteoglycan 5 (CSPG5) or an antibody fragment thereof, a hybridoma which produces the antibody or the antibody fragment thereof, a nucleic acid comprising a nucleotide sequence encoding the antibody or the antibody fragment thereof, a transformant cell comprising a vector comprising the nucleic acid, a method for producing the antibody or the antibody fragment thereof, a composition comprising the antibody or the antibody fragment thereof, and a method for detecting or measuring an antigen present in the brain, a method for diagnosing or treating a brain disease, a method for enhancing the property of accumulating in a brain of an antibody, and a method for increasing the amount of an antibody in the brain, each of which using the antibody or the antibody fragment thereof, and the like.

Abstract: The invention relates to an antibody which binds to myelin oligodendrocyte glycoprotein (MOG), an antibody fragment thereof, a hybridoma which produces the antibody or the antibody fragment, a nucleic acid containing a nucleotide sequence which encodes the antibody or the antibody fragment, a transformant cell containing a vector containing the nucleic acid, a method for producing the antibody or the antibody fragment, a composition containing the antibody or the antibody fragment and a method for detecting or measuring an antigen that is present in the brain, a method for diagnosing or treating a brain disease, a method for improving the property of an antibody of accumulating in the brain and a method for increasing the amount of an antibody in the brain which use the antibody or the antibody fragment.

Abstract: A pressure sensor has a stem in which a pressure introduction hole into which a pressure medium is introduced and a diaphragm deformable according to the pressure of the pressure medium are formed, and a strain detecting element which is arranged on the diaphragm via an insulating film and being configured to output a detection signal according to the deformation of the diaphragm. The strain detecting element is configured to have a portion made of polysilicon. A low doping layer having a higher electrical resistivity than polysilicon and a higher crystallinity than the insulating film is arranged between the insulating film and the strain detecting element.

Abstract: A tag indicating an attribute of the tag by an electromagnetic wave reflection characteristic, the tag including a substrate (11), and a conductor pattern layer (12) formed on the substrate (11) and having first and second slots (13a) and (13b) disposed adjacent to each other, in which the first slot (13a) constitutes a first resonance element (13Qa) having a resonance frequency at a first frequency, the second slot (13b) constitutes a second resonance element (13Qb) having a resonance frequency at a second frequency higher than the first frequency, and when irradiation with the electromagnetic waves is performed, a Q value of a resonance peak appearing at the first frequency is higher than a Q value of a resonance peak appearing at the first frequency when the first slot (13a) alone constitutes a resonance structure of the tag.

Abstract: The purpose of the present invention is to provide a bispecific antibody containing an antigen-binding domain which binds to CD40 and an antigen-binding domain which binds to the Epithelial Cell Adhesion Molecule (EpCAM). This invention pertains to a bispecific antibody containing an antigen-5 binding domain which binds to CD40 and an antigen-binding domain which binds to EpCAM.

Abstract: The invention relates to an antibody which binds to cell adhesion molecule 3 (CADM3) or an antibody fragment thereof, a hybridoma which produces the antibody or the antibody fragment thereof, a nucleic acid comprising a nucleotide sequence encoding the antibody or the antibody fragment thereof, a transformant cell comprising a vector comprising the nucleic acid, a method for producing the antibody or the antibody fragment thereof, a composition comprising the antibody or the antibody fragment thereof, and a method for detecting or measuring an antigen present in the brain, a method for diagnosing or treating a brain disease, a method for enhancing the property of accumulating in a brain of an antibody, and a method for increasing the amount of an antibody in the brain, each of which using the antibody or the antibody fragment thereof, and the like.

Abstract: An object of the present invention is to provide a glove which, while having a cuff, can be easily donned and removed using just one hand.

Abstract: A toner cartridge for storing toner to be supplied to an image forming apparatus, includes a container in which the toner is stored and including a first wall having a filling port through which the toner is filled, and a second wall having a ventilation port sealable by a plug, the plug sealing the port during operation of the cartridge and is removed during maintenance of the cartridge to enable air to be supplied into the container through the port, a paddle configured to rotate to stir the toner between the first and second walls of the container, and a paddle gear connected to the paddle and through which a rotation force is transmitted to the paddle. The gear has a through hole that aligns with the ventilation port in a first direction parallel to a rotation axis of the gear when the gear is at a predetermined rotational position.

Abstract: An object of the present invention is to provide a bispecific antibody comprising an antigen-binding domain that binds to CD40 and an antigen-binding domain that binds to an epithelial cell adhesion molecule (EpCAM). The present invention relates to a bispecific antibody comprising an antigen-binding domain that binds to CD40 and an antigen-binding domain that binds to EpCAM.

Abstract: A particle accelerator system including a particle accelerator that accelerates charged particles, a signal source that outputs high frequency power for accelerating the charged particles in the particle accelerator, an amplifying unit that amplifies the high frequency power from the signal source, and supplies the high frequency power to the particle accelerator, the amplifying unit including a plurality of semiconductor amplifiers using a semiconductor, and a control unit that controls an operation of the amplifying unit. The control unit controls output of at least one of the plurality of semiconductor amplifiers.

Abstract: A detecting system includes: a sensor (10) that includes an antenna unit (11) formed with a metal pattern, and a back surface reflector (13) that faces the antenna unit (11) via an isolation layer (12); and a reader (20) that transmits electromagnetic waves (Fa) to the sensor (10), receives reflected waves (Fr) from the sensor (10), and compares the reflection characteristics of the sensor (10) detected from the reflected waves (Fr) with the reflection characteristics of the sensor (10) stored in advance, to detect a state change in the sensor (10).

Abstract: According to one embodiment, an information collection system comprises a transmitter, a receiver, and a processor. The transmitter emits a signal. The receiver receives the signal. The processor calculates a distance between the transmitter and the receiver from a strength of the signal received by the receiver. The processor calculating the distance between the transmitter and the receiver from the strength of the signal for each of the signals received during a first interval, and using an average distance as the distance between the transmitter and the receiver, the average distance being obtained by averaging the plurality of calculated distances.

Abstract: According to one embodiment, the developing device includes a developing case containing toner, a mixer configured to diffuse the toner in the developing case, and a developing roller configured to develop a latent image formed on an image carrier. The developing case includes a circulation path through which air containing the toner flows. The developing roller is partially exposed from the developing case. The developing roller includes a sleeve rotating along with the movement of the image carrier and a plurality of magnetic pole portions disposed inside the sleeve. The developing roller holds the toner on the sleeve and supplies the toner to the image carrier to develop the latent image. The developing device further includes a magnet disposed apart from the developing roller. The magnet faces one of the magnetic pole portions across the sleeve.

Abstract: An objective is to provide an Fc-modified antibody or the like having a long serum half-life according to a CCAP method, more specifically, an antibody or the like where IgBP is bound to only one site, based on findings of the inventors. Provided is an objective antibody or the like by purification and production of an Fc-modified antibody or the like with a column bound to an Fc region of an antibody. Specifically, an antibody where only one of two binding sites of Fc is selectively modified is provided by allowing an IgBP-bound antibody produced by a CCAP method to adsorb to a carrier of an IgBP-immobilized column, or forming a state where only one Fc of an antibody is bound to an IgBP binding column and then adding a peptide reagent for CCAP to the column to perform a reaction of a CCAP method in the column.

Abstract: An object of the present invention is to provide a glove which, while having a cuff, can be easily donned and removed using just one hand.

Abstract: The power converter includes a capacitor connected to a power conversion unit, and a busbar module having a busbar covered with a molded insulating resin. The busbar module includes a fixed portion provided integrally with the busbar module and fixed to a casing by a fastener. The fixed portion has a shape protruding toward the capacitor from the busbar when the busbar module and the capacitor are viewed in a height direction. The fixed portion is located between the busbar and the capacitor unit.

Abstract: A tag indicating an attribute of the tag by an electromagnetic wave reflection characteristic, the tag including a substrate (11), and a conductor pattern layer (12) formed on the substrate (11) and having first and second slots (13a) and (13b) disposed adjacent to each other, in which the first slot (13a) constitutes a first resonance element (13Qa) having a resonance frequency at a first frequency, the second slot (13b) constitutes a second resonance element (13Qb) having a resonance frequency at a second frequency higher than the first frequency, and when irradiation with the electromagnetic waves is performed, a Q value of a resonance peak appearing at the first frequency is higher than a Q value of a resonance peak appearing at the first frequency when the first slot (13a) alone constitutes a resonance structure of the tag.

Abstract: An object of the present invention is to provide a glove which, while having a cuff, can be easily donned and removed using just one hand.