Abstract: The present invention relates to macrocyclic indole derivatives of general formula (I): in which R1, R2, R3, R4, R5, R6, A and L are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds, and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredients.

Abstract: Physical object boundary detection techniques and systems are described. In one example, an augmented reality module generates three dimensional point cloud data. This data describes depths at respective points within a physical environment that includes the physical object. A physical object boundary detection module is then employed to filter the point cloud data by removing points that correspond to a ground plane. The module then performs a nearest neighbor search to locate a subset of the points within the filtered point cloud data that correspond to the physical object. Based on this subset, the module projects the subset of points onto the ground plane to generate a two-dimensional boundary. The two-dimensional boundary is then extruded based on a height determined from a point having a maximum distance from the ground plane from the filtered cloud point data.

Abstract: A method is provided for providing target object information to a mobile interface device user in a dynamic structural environment. The method includes receiving from the mobile interface device a request for target object information associated with a target object in the dynamic structural environment. A pose of the mobile interface device relative to the target object is determined accounting for spatial differences in the environment coordinate system resulting from changes in the dynamic structure. The method also includes assembling AR target object information for transmission to and display on the mobile interface device and transmitting the AR target object information to the mobile interface device for display in conjunction with a real-time view of the target object.

Abstract: Various embodiments of the present disclosure provide a workpiece-contact element for a fastener pusher. In one embodiment, the workpiece-contact element includes an attachment side, a workpiece-contact surface, and one or more fastener-exit surfaces defining a fastener-exit throughbore having a longitudinal axis and extending through the workpiece-contact surface. The workpiece-contact surface forms an annular protrusion extending away from the attachment side.

Abstract: A handle for carrying watercraft, wherein the handle also functions to securely retain a paddle or oar, the handle comprising a channel for receiving and retaining a paddle or oar using an interference fit. The handle is secured to the watercraft by a strap attached to the watercraft body and passing through a slot in the handle that runs parallel to the channel.

Abstract: The present disclosure provides for a protective covering, which includes a cover portion, an elongated piece of fabric, a first coupling mechanism, and a second coupling mechanism. The cover portion is for a seat cushion. The elongated piece of fabric extends from the cover portion. The first coupling mechanism couples the cover portion to a first end of the elongated piece of fabric. The second coupling mechanism is configured to couple the cover portion to a second end of the elongated piece of fabric.

Abstract: Physical object boundary detection techniques and systems are described. In one example, an augmented reality module generates three dimensional point cloud data. This data describes depths at respective points within a physical environment that includes the physical object. A physical object boundary detection module is then employed to filter the point cloud data by removing points that correspond to a ground plane. The module then performs a nearest neighbor search to locate a subset of the points within the filtered point cloud data that correspond to the physical object. Based on this subset, the module projects the subset of points onto the ground plane to generate a two-dimensional boundary. The two-dimensional boundary is then extruded based on a height determined from a point having a maximum distance from the ground plane from the filtered cloud point data.

Abstract: Provided herein are systems and methods for rapid activation of electronic payment devices with a mobile device. The method includes generating, with at least one processor, activation data corresponding to a non-activated electronic payment device issued to a user, storing, on an activation element associated with the electronic payment device, a unique identifier corresponding to the electronic payment device, receiving, with at least one processor, an activation request from a mobile device in response to the user scanning the activation element with the mobile device, the activation request comprising identification data associated with the user and the unique identifier, determining, with at least one processor, that the activation data matches the identification data, and, in response to determining that the activation data matches the identification data, activating the electronic payment device.

Abstract: Various embodiments of the present disclosure provide a nail with a head having an inwardly curved top surface. In one embodiment, the nail has a longitudinal axis and comprises a head, a shank, and a tip. The head includes a top portion and a bottom portion. The top portion includes an inwardly curved top surface forming a partially spherical cavity, while the bottom portion includes a radially inwardly tapered annular bottom surface. The shank is integrally connected to and extends from the bottom portion of the head. The tip is integrally connected to and extends from the shank and terminates in a free end.

Abstract: Management of pharmaceutical procurement for a pharmaceutical ordering location. A method includes determining a medication need and a drug product preference for an ordering location. The method includes identifying one or more drug products satisfying the medication need by communicating with one or more pharmaceutical suppliers and selecting at least one of the one or more drug products based on the drug product preference. The method includes generating a recommended order for the ordering location comprising the at least one of the one or more drug products.

Abstract: Provided is a system, method, and computer program product for conducting secure transactions with at least two appliances. The method includes monitoring audio data with a first appliance including a processor, a speaker, and a microphone; detecting, with the first appliance, an audible request to initiate a transaction from a user from the audio data; communicating, with the first appliance, a transaction request to at least one remote server in response to detecting the audible request to initiate the transaction; detecting, with the first appliance, a credential message received by the first appliance directly from a second appliance via an audio transmission, the credential message corresponding to the transaction request and including a limited use key provided to the second appliance from the at least one remote server or another remote server; and in response to detecting the credential message, initiating, with the first appliance, the transaction based on the limited use key.

Abstract: Electronic stored value cards (“eSVCs”) may be susceptible to fraud, theft, or unauthorized access. As eSVCs are still relatively new, the eSVC industry may not have fully developed sufficient safeguards to prevent such fraud, therft, and unauthorized access. Disclosed herein are systems, apparatus, and methods for evaluating whether or not to provide a service, which may include displaying, funding, or authorizing an eSVC. The evaluation may be in response to a request for such a service. The evaluation may be based on a risk due to fraud, theft, or unathorized access.

Abstract: A connector assembly attaches downhole tools to one another to form a tool string. The connector assembly includes male and female subs, each with latch ends that selectively latch to one another. Ends of the subs distal from their latch ends are configured for attachment to the downhole tools. A plug assembly is in one of the subs and a socket assembly is disposed in the other sub; the plug and socket assemblies mate with one another when the subs attach. Mating the plug and socket assemblies forms a signal communication path through the connector assembly so that adjacent tools are in signal communication. The plug and socket assemblies and male and female subs are annular and circumscribe a bore that extends axially through the connector assembly. Downhole tools that attach to opposing ends of the connector assembly are in communication through the bore in the connector assembly.

Abstract: Within the EMV payment specification, the use of an unattended terminal to accept a payment is allowed. Creating a device that has both the EMV level 1 (L1) and level 2 (L2) payment components combined with a virtual merchant creates a “card present” transaction for an on-line or e-commerce merchant. This device can be called a personal Point of Sale (pPOS). This specification discloses personal Point of Sale (pPOS) devices and methods that can provide for card present e-commerce transactions. In some embodiments, a pPOS device can include only a secure microcontroller function (MCF), a payment kernel, a secure element, and an interface to an external system with an EMV level 3 (L3) payment application. In some embodiments, a pPOS device can further include a reader. In some embodiments, a pPOS device can still further include a sensor switch and/or a user interface function.

Abstract: A method is disclosed. A digital assistant device receives a biometric sample from a user and then converts the biometric sample to a biometric template. The digital assistant device can scan for user devices in communication range of the digital assistant device, thereby receiving user device identifiers. The digital assistant device can transmit, to a server computer, an authentication request comprising the biometric template and at least one user device identifier. The digital assistant device can then receive a cryptogram request message comprising the at least one user device identifier, from the server computer. The digital assistant device can transmit, to a user device corresponding to the at least one user device identifier, the cryptogram request message and can then receive a cryptogram. The digital assistant device can then transmit the cryptogram to the server computer. The server computer verifies the cryptogram before further processing of a transaction.

Abstract: The present disclosure provides for a protective covering, which includes a cover portion, an elongated piece of fabric, a first coupling mechanism, and a second coupling mechanism. The cover portion is for a seat cushion. The elongated piece of fabric extends from the cover portion. The first coupling mechanism couples the cover portion to a first end of the elongated piece of fabric. The second coupling mechanism is configured to couple the cover portion to a second end of the elongated piece of fabric.

Abstract: A saddle tree comprising a back engaging element (3) for engaging and sitting on the back of an animal and a seat forming element (4) resiliently coupled to the back engaging element (3) adjacent the pommel (5) by a pair of resilient mounting members (8). A limit strap (17) is anchored to the back engaging element (3) and is adjustably coupled to the seat forming element (4) by a ratchet mechanism (20). The limit strap (17) terminates in a grippable element (32) which is releasably grippable by the ratchet mechanism (20). By urging the grippable element (32) in the direction of the arrow A through the ratchet mechanism (20), the limit of upward travel of the seat forming element (4) relative to the back engaging element (3) is reduced, thereby effectively hardening the saddle.

Abstract: A carpenter bee trap includes a plurality of walls surrounding a trap cavity, at least one entrance opening formed through at least one of the plurality of walls, a bottom wall coupled to a bottom of the plurality of walls, an exit opening formed through one of the walls or the bottom wall, a container disposed within the trap cavity and extending through the exit opening and into the external environment, and a funnel disposed within the cavity to direct carpenter bees into the container.

Abstract: A snack food container having a square base, side walls substantially consisting of four right triangular panels and two isosceles triangular panels, and a flat, two dimensional end seal. The container is opened by use of a tear feature just below the end seal. The container is of paperboard construction and is resealable by virtue of a score line on each side of the container located below the end seal in combination with a horizontal cut through the container located below one score line. After opening, the container can be resealed by folding the container over the score lines towards the horizontal cut. An edge of the container is then secured in the horizontal cut.