Patents by Inventor Paul A. Bottomley

Paul A. Bottomley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7848788
    Abstract: Herein is disclosed a magnetic resonance imaging probe, having a probe shaft including a magnetic resonance antenna, and a spring tip attached to a distal end of the antenna.
    Type: Grant
    Filed: April 11, 2002
    Date of Patent: December 7, 2010
    Assignees: The Johns Hopkins University, SurgiVision, Inc.
    Inventors: Steve Tulley, Albert C. Lardo, Parag Karmarkar, Elliot McVeigh, Henry R. Halperin, Christine Enger McNamara, Paul A. Bottomley, Ergin Atalar, Xiaoming Yang
  • Patent number: 7844319
    Abstract: Herein is disclosed a probe, including a first electrode disposed at least partially on the probe surface, a second electrode disposed at least partially on the probe surface, a first conductor electrically coupled to the first electrode, a second conductor electrically coupled to the second electrode, and a reactive element electrically coupling the first conductor and the second conductor.
    Type: Grant
    Filed: April 15, 2002
    Date of Patent: November 30, 2010
    Inventors: Robert C. Susil, Gwyneth Susil, Ergin Atalar, Albert C. Lardo, Henry R. Halperin, Ronald D. Berger, Hugh Calkins, Paul Bottomley
  • Publication number: 20100274252
    Abstract: Featured is a reduction instrument being configured and arranged to allow correction of vertebral translation and applying distraction across a segment in an independent fashion. Such a reduction instrument embodies one or more identical modules that are configured as needed for correcting the deformity. In more particular embodiments, each of the one or more modules has two degrees of freedom (DOF) with uncoupled orthogonal translations. Such a reduction instrument allows the reorientation of the vertebral segment as needed via uncoupled orthogonal translations. Such a reduction instrument also is usable in combination with a plurality of vertebral anchors, such vertebral anchors being any such vertebral anchors as are know to those skilled in the art (e.g., conventional spinal pedicle screw instrumentation) or hereinafter developed so as to form a spinal implant system. Also featured are treatment methods utilizing such a reduction instrument.
    Type: Application
    Filed: April 23, 2010
    Publication date: October 28, 2010
    Applicant: The Johns Hopkins University
    Inventors: Paul A. Bottomley, Shashank Sathyanarayana
  • Patent number: 7816918
    Abstract: Featured is a device for NMR or MRI signals from excited nuclei as well as related apparatus, systems and methods. The device includes a strip array antenna including one or more conductor and N reactive tuning components, where N is an integer ?1 at least one of the N reactive components is electrically coupled to each of the one or more conductors as well as to ground/virtual ground. The apparent electrical length of the conductors is tuned with the reactive tuning components so it is equal to be about n?/4, where n is an integer ?1 and ? is the wavelength of the signal to be detected. The length of the strip also is such as to be substantially in the approximate range of 1.3 times the depth of interest. The strip conductors are also combined with loop coils to form quadrature detectors.
    Type: Grant
    Filed: May 24, 2007
    Date of Patent: October 19, 2010
    Assignee: The Johns Hopkins University
    Inventors: Paul A. Bottomley, Ananda Kumar
  • Publication number: 20100256480
    Abstract: Featured are a device with localized sensitivity to magnetic resonance signals, an imaging system using such a device and MRI methods for performing internal MRI or MRI Endoscopy. Such an MRI method includes introducing an MRI antenna or probe into the specimen to be imaged, the antenna being configured in accordance with the devices described herein, so that the spatial coordinate frame of imaging is inherently locked or defined with respect to the introduced antenna thereby providing imaging of the specimen from the point of view of the antenna. Further such imaging is conducted so that the MRI signal is confined substantially to a volume with respect to a particular region of the antenna or probe.
    Type: Application
    Filed: December 31, 2007
    Publication date: October 7, 2010
    Applicant: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Paul A. Bottomley, Shashank Sathyanarayana
  • Publication number: 20090171421
    Abstract: Some embodiments are directed to MRI/RF compatible medical interventional devices.
    Type: Application
    Filed: October 20, 2006
    Publication date: July 2, 2009
    Inventors: Ergin Atalar, Justin Allen, Paul Bottomley, William Eldelstein, Parag V. Karmarkar
  • Publication number: 20090015256
    Abstract: Featured is a device for NMR or MRI signals from excited nuclei as well as related apparatus, systems and methods. The device includes a strip array antenna including one or more conductor and N reactive tuning components, where N is an integer ?1 at least one of the N reactive components is electrically coupled to each of the one or more conductors as well as to ground/virtual ground. The apparent electrical length of the conductors is tuned with the reactive tuning components so it is equal to be about n?/4, where n is an integer ?1 and ? is the wavelength of the signal to be detected. The length of the strip also is such as to be substantially in the approximate range of 1.3 times the depth of interest. The strip conductors are also combined with loop coils to form quadrature detectors.
    Type: Application
    Filed: May 24, 2007
    Publication date: January 15, 2009
    Applicant: The Johns Hopkins University
    Inventors: Paul A. Bottomley, Ananda Kumar
  • Publication number: 20080262584
    Abstract: MRI/RF compatible leads include at least one conductor, a respective conductor having at least one segment with a multi-layer stacked coil configuration. The lead can be configured so that the lead heats local tissue less than about 10 degrees Celsius (typically about 5 degrees Celsius or less) or does not heat local tissue when a patient is exposed to target RF frequencies at a peak input SAR of at least about 4 W/kg and/or a whole body average SAR of at least about 2 W/kg. Related leads and methods of fabricating leads are also described.
    Type: Application
    Filed: March 13, 2008
    Publication date: October 23, 2008
    Inventors: Paul A. Bottomley, Parag V. Karmarkar, Justin M. Allen, William A. Edelstein, Peter Piferi, Brian Gore, J. Michael Shifflette
  • Publication number: 20080243218
    Abstract: RF/MRI compatible leads include at least one conductor that turns back on itself at least twice in a lengthwise direction, and can turn back on itself at least twice at multiple locations along its length. The at least one electrical lead can be configured so that the lead heats local tissue less than about 10 degrees Celsius (typically about 5 degrees Celsius or less) or does not heat local tissue when a patient is exposed to target RF frequencies at a peak input SAR of at least about 4 W/kg and/or a whole body average SAR of at least about 2 W/kg. Related devices and methods of fabricating leads are also described.
    Type: Application
    Filed: March 13, 2008
    Publication date: October 2, 2008
    Inventors: Paul A. Bottomley, Parag V. Karmarkar, Justin M. Allen, William A. Edelstein
  • Publication number: 20070295327
    Abstract: Use of stimuli in order to provide association with a training regime or other behavior modification technique is known. With regard to olfactory stimulation it will be appreciated that it is necessary that the olfactory is actively provided in the sense the it is not a continuous stimulation but provided in pulses for regular association. Without such distinct presentation of the olfactory stimulus a user may become desensitized. In order to achieve this the present olfactory stimulator comprises a regulator and specific delivery techniques such as the use of a fan or piston to direct the olfactory towards the user's nose.
    Type: Application
    Filed: September 21, 2005
    Publication date: December 27, 2007
    Applicant: CAN-DO CORPORATION LTD.
    Inventor: Paul Bottomley
  • Publication number: 20070265684
    Abstract: The use of stimuli in order to create association between training regimes subconsciously is known. Unfortunately, in highly noisy and other polluted environments it is difficult to provide ongoing reinforcement of previous behavior modification and training. By providing a stimulus phrase which comprises two or more stimuli in known combinations it is possible to provide keyed association with previous training regimes.
    Type: Application
    Filed: September 21, 2005
    Publication date: November 15, 2007
    Applicant: CAN-DO CORPORATION LTD.
    Inventor: Paul Bottomley
  • Patent number: 7088104
    Abstract: A strip array antenna including a number of conductors (14) that are connected to ground or virtual ground though at least one reactive component (150). The apparent electrical length of conductors (140) is tuned so that it equals an integer multiple of a quarter wavelength at the operating frequency.
    Type: Grant
    Filed: December 31, 2002
    Date of Patent: August 8, 2006
    Assignee: The John Hopkins University
    Inventor: Paul Bottomley
  • Publication number: 20060150821
    Abstract: A food preparation device comprising: a first water chamber for holding a volume of water to be boiled thereby to produce boiled water; and a second water chamber arranged to receive said boiled water and to hold said boiled water prior to: (a) the reheating of said boiled water, thereby to produce reheated water; and (b) the dispensation of said reheated water to a mixing location at which it can mix with concentrated food preparation formulation.
    Type: Application
    Filed: June 2, 2004
    Publication date: July 13, 2006
    Inventors: Claire Paul, Paul Bottomley, Mandy Haberman
  • Publication number: 20050253582
    Abstract: An RF coil assembly for use in a multiple receive-channel MRI system is provided. The RF coil assembly is configured as a multi-turn-element RF coil assembly 200 to operate as a surface-coil array in cooperation with the MRI system 100 which is configured to operate in a multiple-channel receive mode.
    Type: Application
    Filed: October 7, 2004
    Publication date: November 17, 2005
    Inventors: Randy Otto Giaquinto, Harvey Cline, Christopher Hardy, Charles Dumoulin, Paul Bottomley
  • Publication number: 20050062472
    Abstract: A strip array antenna including a number of conductors (14) that are connected to ground or virtual ground though at least one reactive component (150). The apparent electrical length of conductors (140) is tuned so that it equals an integer multiple of a quarter wavelength at the operating frequency.
    Type: Application
    Filed: December 31, 2002
    Publication date: March 24, 2005
    Inventor: Paul Bottomley
  • Patent number: 6675033
    Abstract: The invention describes a system, method, and means for an MRI guidewire that can be visible on an MRI, can act as an antenna and receive MRI signals from surrounding subject matter, and can allow the use of multiple interventional tools without removal of the guidewire from a subject.
    Type: Grant
    Filed: March 24, 2000
    Date of Patent: January 6, 2004
    Assignees: Johns Hopkins University School of Medicine, Surgi-Vision, Inc.
    Inventors: Albert C. Lardo, Xiaoming Yang, Ergin Atalar, Parag Karmarkar, Elliott R. McVeigh, Henry R. Halperin, Christine Enger McNamara, Paul A. Bottomley
  • Patent number: 6628980
    Abstract: The apparatus, systems and methods of the present invention provide for MRI sleeves, probes, and combinations thereof adapted for insertion into a subject, in order to internally image regions of the subject.
    Type: Grant
    Filed: March 26, 2001
    Date of Patent: September 30, 2003
    Assignee: Surgi-Vision, Inc.
    Inventors: Ergin Atalar, Paul A. Bottomley, Parag Karmarkar, Albert C. Lardo, Elias Zerhouni
  • Patent number: 6549800
    Abstract: The systems and methods of the present invention provide for MRI probes adapted for insertion into a plurality of body orifices, in order to evaluate the anatomy of proximate anatomic structures, to diagnose abnormalities thereof and to treat the diagnosed abnormalities. MRI probes are described that are suitable for use in the mediastinum, in the pancreaticohepaticobiliary system, in the tracheobronchopulmonary system, in the head and neck, in the genitourinary system, the gastrointestinal system, the vascular system, and in the evaluation, diagnosis and treatment of internal fluid collections.
    Type: Grant
    Filed: April 14, 2000
    Date of Patent: April 15, 2003
    Assignee: Johns Hopkins Unversity School of Medicine
    Inventors: Ergin Atalar, Paul A. Bottomley, Elias Zerhouin, Henry Halperin, Elliot McVeigh, Albert C. Lardo
  • Publication number: 20030028095
    Abstract: Herein is disclosed a magnetic resonance imaging probe, having a probe shaft including a magnetic resonance antenna, and a spring tip attached to a distal end of the antenna.
    Type: Application
    Filed: April 11, 2002
    Publication date: February 6, 2003
    Inventors: Steve Tulley, Albert C. Lardo, Parag Karmarkar, Elliot McVeigh, Henry R. Halperin, Christine Enger McNamara, Paul A. Bottomley, Ergin Atalar, Xiaoming Yang
  • Publication number: 20020045816
    Abstract: The apparatus, systems and methods of the present invention provide for MRI sleeves, probes, and combinations thereof adapted for insertion into a subject, in order to internally image regions of the subject.
    Type: Application
    Filed: March 26, 2001
    Publication date: April 18, 2002
    Inventors: Ergin Atalar, Paul A. Bottomley, Parag Karmarkar, Albert C. Lardo, Elias Zerhouni