Abstract: Elongate medical devices such as guidewires can be formed from a core wire and a preformed distal cap that is configured to fit over a distal end of the core wire. The distal cap can be attached using a variety of techniques. In particular, the distal cap can be attached to the core wire using laser welding.

Abstract: Medical devices and methods of manufacturing medical devices. The medical devices include an elongate member having a proximal portion and a distal portion and a connector assembly disposed adjacent the elongated member to connect the proximal and distal portions, the connector assembly including a radiopaque marker.

Abstract: Elongate medical devices such as guidewires can be formed from a core wire and a preformed distal cap that is configured to fit over a distal end of the core wire. The distal cap can be attached using a variety of techniques. In particular, the distal cap can be attached to the core wire using laser welding.

Abstract: Medical devices and methods of manufacturing medical devices. The medical devices include an elongate member having a proximal portion and a distal portion and a connector assembly disposed adjacent the elongated member to connect the proximal and distal portions, the connector assembly including a radiopaque marker.

Abstract: Alternative designs, materials and manufacturing methods for guidewires. Some embodiments pertain to a composite guidewire having proximal and distal section, and a connector adapted and configured for permanently joining the proximal section to the distal section. In some embodiments, at least one of the sections is made of a linear-elastic nickel-titanium alloy. Several alternative guidewire tip designs including coiled safety/shaping structures are also disclosed.

Abstract: Alternative designs, materials and manufacturing methods for guidewires. Some embodiments pertain to a composite guidewire having proximal and distal section, and a connector adapted and configured for permanently joining the proximal section to the distal section. In some embodiments, at least one of the sections is made of a linear-elastic nickel-titanium alloy. Several alternative guidewire tip designs including coiled safety/shaping structures are also disclosed.

Abstract: Alternative designs and materials suitable for connecting different guidewire sections together. More particularly, connecting two portions of a guidewire having different material compositions with a connector having a third composition which is readily weldable to each of the dissimilar portions of the guidewire. A transition area may be designed to provide a region of desired flexibility characteristics.

Abstract: Alternative designs, materials and manufacturing methods for guidewires. Some embodiments pertain to a composite guidewire having proximal and distal section, and a connector adapted and configured for permanently joining the proximal section to the distal section. In some embodiments, at least one of the sections is made of a linear-elastic nickel-titanium alloy. Several alternative guidewire tip designs including coiled safety/shaping structures are also disclosed.

Abstract: Devices and methods for coupling guidewire system components are disclosed. A guidewire system includes a first wire having a first end and a second wire having a second end which may be selectively coupled to the first end of the first wire. Such guidewire systems are useful as guidewire extension systems.

Abstract: Alternative designs, materials and manufacturing methods for medical devices. Some embodiments disclosed deal with attachment of an elongated structure, such as a wire or ribbon, or a tubular member, such as a coil, to an elongated member in an elongated device. For example, an elongated core member having defining an outer surface, and an elongated structure including a first portion and a second expanded portion along the length thereof can be provided. An attachment member, such as a centering ring, or the like, is disposed about a portion of the elongated core member and a part of the first portion of the elongated structure. The attachment member defines a lumen and having an inner surface. Part of the first portion of the elongated structure is disposed between the inner surface of the attachment member and the outer surface of the elongated core member.

Abstract: Alternative designs, materials and manufacturing methods for medical devices. Some embodiments pertain to a composite medical device including an first section having an end, and a connector member defining an opening therein, wherein the end of the elongated section extends into the opening. A bismuth alloy connector material is disposed within the opening, and the connector material is configured to expand when solidified to exert a compressive force within the connector member.

Abstract: Elongate medical devices such as guidewires can be formed from a core wire and a preformed distal cap that is configured to fit over a distal end of the core wire. The distal cap can be attached using a variety of techniques. In particular, the distal cap can be attached to the core wire using laser welding.

Abstract: Medical devices and methods of manufacturing medical devices. The medical devices include an elongate member having a proximal portion and a distal portion and a connector assembly disposed adjacent the elongated member to connect the proximal and distal portions, the connector assembly including a radiopaque marker.

Abstract: A guide wire that can be placed in a patient's vasculature or body cavity. The guide wire includes one or more radiopaque markers that can be visualized by fluoroscopy or the like. The markers are preferably spaced apart longitudinally along the guide wire such that the markers and/or spaces between the markers can be used to make measurements of anatomical or artificial structures within the body.

Abstract: Alternative designs, materials and manufacturing methods for connecting different guidewire sections together.

Abstract: Alternative designs, materials and manufacturing methods for guidewires. Some embodiments pertain to a composite guidewire having proximal and distal section, and a connector adapted and configured for permanently joining the proximal section to the distal section. In some embodiments, at least one of the sections is made of a linear-elastic nickel-titanium alloy. Several alternative guidewire tip designs including coiled safety/shaping structures are also disclosed.

Abstract: Devices and methods for coupling guidewire system components are disclosed. A guidewire system includes a first wire having a first end and a second wire having a second end which may be selectively coupled to the first end of the first wire. Such guidewire systems are useful as guidewire extension systems.

Abstract: A guide wire that can be placed in a patient's vasculature or body cavity. The guide wire includes one or more radiopaque markers that can be visualized by fluoroscopy or the like. The markers are preferably spaced apart longitudinally along the guide wire such that the markers and/or spaces between the markers can be used to make measurements of anatomical or artificial structures within the body.

Abstract: The disclosed process for making a high % solids, one-part, curable, essentially flowable or pumpable, high equivalent weight polyurethane (i.e., polyol-polyisocyanate adduct) prepolymer composition involves de-watering the polyol component of the reaction mixture with an alkaline earth metal oxide, preferably calcium oxide; adding the minimum acceptable level of catalyst for the NCO/polyol reaction; exothermically reacting a partially hindered aliphatic polyisocyanate such as isophorone diisocyanate (IPDI) and a partially hindered aromatic polyisocyanate such as 2,4-tolylene diisocyanate seriatim, so that at least about one-fourth of the IPDI reacts before the 2,4-TDI is added; and then adding more catalyst for the curing (e.g. moisture cure) reaction.