Abstract: A system and method for implementing a merchant loyalty program is disclosed. The invention includes receiving purchase data, wherein the purchase data comprises a consumer account code, a purchase amount, and a service establishment code; associating the service establishment code with a merchant proprietor rewards account code; calculating a reward amount based on the purchase amount; and, crediting a merchant proprietor reward account with at least a portion of said reward amount.

Abstract: One embodiment may take the form of a flexible creation animated by magnets or electromagnets brought near the flexible creation. Iron particles blended with a flexible material of the flexible creation may interact with the magnetic fields generated by the magnets, causing the object or portions of the object to move toward or away from the controlling magnets, thereby animating the object.

Abstract: A system and method for implementing a merchant loyalty program is disclosed. The invention includes receiving purchase data, wherein the purchase data comprises a consumer account code, a purchase amount, and a service establishment code; associating the service establishment code with a merchant proprietor rewards account code; calculating a reward amount based on the purchase amount; and, crediting a merchant proprietor reward account with at least a portion of said reward amount.

Abstract: Embodiments of the present invention are directed to a method for performing non-contact based determination of the position of an implement. In one embodiment, the method includes using a non-contact based measurement system to determine a first measurement comprising the position of the implement relative to a mobile machine coupled with the implement, determining a second measurement comprising the geographic position of the mobile machine and determining the geographic position of the implement using the first measurement and the second measurement.

Abstract: The invention relates to isoindolones of formula, (I) with anti-cancer and/or anti-inflammatory activity and more specifically with MEK kinase inhibitory activity. The invention provides compositions and methods useful for inhibiting abnormal cell growth, treating a hyperproliferative disorder, or treating an inflammatory disease in a mammal. The invention also relates to methods of using the compounds for in vitro, in situ, and in vivo diagnosis or treatment of mammalian cells, or associated pathological conditions.

Abstract: Embodiments of the present invention are directed to a method and system for performing non-contact based determination of the position of an implement. In one embodiment, a non-contact based measurement system is used to determine the relative position of an implement coupled with a mobile machine. The geographic position of the mobile machine is determined and the geographic position of said implement based upon the geographic position of the mobile machine and the position of the implement relative to the mobile machine.

Abstract: One embodiment may take the form of a flexible creation animated by magnets or electromagnets brought near the flexible creation. Iron particles blended with a flexible material of the flexible creation may interact with the magnetic fields generated by the magnets, causing the object or portions of the object to move toward or away from the controlling magnets, thereby animating the object.

Abstract: An input device for tracking three-dimensional movements. The input device includes a tracking structure and is in electronic communication with a computing device. The tracking structure is detectable by a tracking device. The tracking structure is configured so that as the input device is deformed, the tracking structure deforms correspondingly.

Abstract: The present invention relates to a method and corresponding system for predicting the perceived spatial quality of sound processing and reproducing equipment. According to the invention a device to be tested, a so-called device under test (DUT), is subjected to one or more test signals and the response of the device under test is provided to one or more means for deriving metrics, i.e. a higher-level representation of the raw data obtained from the device under test. The derived one or more metrics is/are provided to suitable predictor means that “translates” the objective measure provided by the one or more metrics to a predicted perceived spatial quality. To this end said predictor means is calibrated using listening tests carried out on real listeners. By means of the invention there is thus provided an “instrument” that can replace expensive and time consuming listening tests for instance during development of various audio processing or reproduction systems or methods.

Abstract: A system and method for implementing a merchant loyalty program is disclosed. The invention includes receiving purchase data, wherein the purchase data comprises a consumer account code, a purchase amount, and a service establishment code; associating the service establishment code with a merchant proprietor rewards account code; calculating a reward amount based on the purchase amount; and, crediting a merchant proprietor reward account with at least a portion of said reward amount.

Abstract: One particular implementation of the present invention may involve a flexible material infused with fine iron particles to form at least a portion of a flexible character or object. The flexible creation may be animated by one or more magnets or electromagnets brought near the flexible creation such that the iron particles blended with the flexible material may interact with the magnetic fields generated by the magnets. The infused iron particles may be attracted to the magnets, causing the object or portions of the object to move toward or away from the controlling magnets, thereby animating the object or portions of the object. Another implementation may use a magnetic field of a magnet to create an iron-infused flexible plant-like object that may be animated by a magnet. The object may be constructed of a flexible iron-infused material that is introduced into the magnetic field while the material is in a liquid or semi-liquid state.

Abstract: A system and method for implementing a merchant loyalty program is disclosed. The invention includes receiving purchase data, wherein the purchase data comprises a consumer account code, a purchase amount, and a service establishment code; associating the service establishment code with a merchant proprietor rewards account code; calculating a reward amount based on the purchase amount; and, crediting a merchant proprietor reward account with at least a portion of said reward amount.

Abstract: Compounds of the formula (I): wherein A and B together represent an optionally substituted, fused aromatic ring; X can be NRX or CRXRY; if X?NRX then n is 1 or 2 and if X?CRXRY then n is 1; RX is selected from the group consisting of H, optionally substituted C1-20 alkyl, C5-20 aryl, C3-20 heterocyclyl, amido, thioamido, ester, acyl, and sulfonyl groups; RY is selected from H, hydroxy, amino; or RX and RY may together form a spiro-C3-7 cycloalkyl or heterocyclyl group; RC1 and RC2 are both hydrogen, or when X is CRXRY, RC1, RC2, RX and RY, together with the carbon atoms to which they are attached, may form an optionally substituted fused aromatic ring; and R1 is selected from H and halo.

Abstract: The invention relates to bicyclic heterocycles of formulae I and II with anti-cancer and/or anti-inflammatory activity and more specifically with MEK kinase inhibitory activity. The invention provides compositions and methods useful for inhibiting abnormal cell growth, treating a hyperproliferative disorder, or treating an inflammatory disease in a mammal. The invention also relates to methods of using the compounds for in vitro, in situ, and in vivo diagnosis or treatment of mammalian cells, or associated pathological conditions.

Abstract: Compounds of the formula (I): wherein A and B together represent an optionally substituted, fused aromatic ring; X can be NRX or CRXRY; if X?NRX then n is 1 or 2 and if X?CRXRY then n is 1; RX is selected from the group consisting of H, optionally substituted C1-20 alkyl, C5-20 aryl, C3-20 heterocyclyl, amido, thioamido, ester, acyl, and sulfonyl groups; RY is selected from H, hydroxy, amino; or RX and RY may together form a spiro-C3-7 cycloalkyl or heterocyclyl group; RC1 and RC2 are both hydrogen, or when X is CRXRY, RC1, RC2, RX and RY, together with the carbon atoms to which they are attached, may form an optionally substituted fused aromatic ring; and R1 is selected from H and halo.

Abstract: The invention relates to isoindolones of formula, (I) with anti-cancer and/or anti-inflammatory activity and more specifically with MEK kinase inhibitory activity. The invention provides compositions and methods useful for inhibiting abnormal cell growth, treating a hyperproliferative disorder, or treating an inflammatory disease in a mammal. The invention also relates to methods of using the compounds for in vitro, in situ, and in vivo diagnosis or treatment of mammalian cells, or associated pathological conditions.

Abstract: A compound of the formula II wherein one of R1 and R2 is halo and the other is H or halo; R3 is C1-C4 straight or branched chain, optionally fluorinated, alkyl; R4 is H; or R3 together with R4 and the adjoining backbone carbon defines: a spiro-C5-C7 cycloalkyl, optionally substituted with 1 to 3 substituents selected from halo, hydroxyl, C1-C4 alkyl or C1-C4 haloalkyl; or optionally bridged with a methylene group; or a C4-C6 saturated heterocycle having a hetero atom selected from O, NRa, S, S(?O)2; where Ra is H, C1-C4 alkyl or CH3C(?O); R5 is independently selected from H or methyl; E is —C(?O)—, —S(?O)m—, —NR5S(?O)m—, —NR5C(?O)—, —OC(?O)—, R6 is a stable, optionally substituted, monocyclic or bicyclic, carbocycle or hetorocycle; m is independently 0, 1 or 2; are inhibitors of cathepsin K and useful in the treatment or prophylaxis of osteoporosis.

Abstract: A compound of the formula II wherein one of R1 and R2 is halo and the other is H or halo; R3 is C1-C4 straight or branched chain, optionally fluorinated, alkyl; R4 is H; or R3 together with R4 and the adjoining backbone carbon defines: a spiro-C5-C7 cycloalkyl, optionally substituted with 1 to 3 substituents selected from halo, hydroxyl, C1-C4 alkyl or C1-C4 haloalkyl; or optionally bridged with a methylene group; or a C4-C6 saturated heterocycle having a hetero atom selected from O, NRa, S, S(?O)2; where Ra is H, C1-C4 alkyl or CH3C(?O); R5 is independently selected from H or methyl; E is —C(?O)—, —S(?O)m—, —NR5S(?O)m—, —NR5C(?O)—, —OC(?O)—, R6 is a stable, optionally substituted, monocyclic or bicyclic, carbocycle or heterocycle; m is independently 0,1 or 2; are inhibitors of cathepsin K and useful in the treatment or prophylaxis of osteoporosis.

Abstract: One particular implementation of the present invention may involve a flexible material infused with fine iron particles to form at least a portion of a flexible character or object. The flexible creation may be animated by one or more magnets or electromagnets brought near the flexible creation such that the iron particles blended with the flexible material may interact with the magnetic fields generated by the magnets. The infused iron particles may be attracted to the magnets, causing the object or portions of the object to move toward or away from the controlling magnets, thereby animating the object or portions of the object. Another implementation may use a magnetic field of a magnet to create an iron-infused flexible plant-like object that may be animated by a magnet. The object may be constructed of a flexible iron-infused material that is introduced into the magnetic field while the material is in a liquid or semi-liquid state.

Abstract: Compounds of the formula (I): wherein A and B together represent an optionally substituted, fused aromatic ring; X can be NRX or CRXRY; if X=NRX then n is 1 or 2 and if X=CRXRY then n is 1; RX is selected from the group consisting of H, optionally substituted C1-20 alkyl, C5-20 aryl, C3-20 heterocyclyl, amido, thioamido, ester, acyl, and sulfonyl groups; RY is selected from H, hydroxy, amino; or RX and RY may together form a spiro-C3-7 cycloalkyl or heterocyclyl group; RC1 and RC2 are both hydrogen, or when X is CRXRY, RC1, RC2, RX and RY, together with the carbon atoms to which they are attached, may form an optionally substituted fused aromatic ring; and R1 is selected from H and halo.